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Article ; Online: Low-profile and wide-band RCS-reduction antenna array based on the metasurface polarization converter.

Tian, Ying / Gao, Huotao / Yao, Wang / Wu, Jiong / Guo, Linyan

2022 Volume 30, Issue 23, Page(s) 41313–41327

Abstract: Antenna elements with a low profile and high front-to-back (FB) ratio mean that no additional reflective cavity is required when forming the array, which greatly helps to simplify and lighten the entire array system. In this paper, we enhance the FB ... ...

Abstract	Antenna elements with a low profile and high front-to-back (FB) ratio mean that no additional reflective cavity is required when forming the array, which greatly helps to simplify and lighten the entire array system. In this paper, we enhance the FB ratio of the antenna to 35 dB while maintaining an ultra-low profile of 0.05 λ
Language	English
Publishing date	2022-11-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.473892
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Corrigendum to "A novel HIF2A mutation causes dyslipidemia and promotes hepatic lipid accumulation" [Pharmacol. Res. 194 (2023) 106851].

Gao, Feiqiong / Yao, Qigu / Zhu, Jiaqi / Chen, Wenyi / Feng, Xudong / Feng, Bing / Wu, Jian / Pacak, Karel / Rosenblum, Jared / Yu, Jiong / Zhuang, Zhengping / Cao, Hongcui / Li, Lanjuan

Pharmacological research

2024 Volume 202, Page(s) 107135

Language	English
Publishing date	2024-03-08
Publishing country	Netherlands
Document type	Published Erratum
ZDB-ID	1003347-6
ISSN	1096-1186 ; 0031-6989 ; 1043-6618
ISSN (online)	1096-1186
ISSN	0031-6989 ; 1043-6618
DOI	10.1016/j.phrs.2024.107135
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: MSC-derived exosomes attenuate hepatic fibrosis in primary sclerosing cholangitis through inhibition of Th17 differentiation.

Chen, Wenyi / Lin, Feiyan / Feng, Xudong / Yao, Qigu / Yu, Yingduo / Gao, Feiqiong / Zhou, Jiahang / Pan, Qiaoling / Wu, Jian / Yang, Jinfeng / Yu, Jiong / Cao, Hongcui / Li, Lanjuan

Asian journal of pharmaceutical sciences

2024 Volume 19, Issue 1, Page(s) 100889

Abstract: Primary sclerosing cholangitis (PSC) is an autoimmune cholangiopathy characterized by chronic inflammation of the biliary epithelium and periductal fibrosis, with no curative treatment available, and liver transplantation is inevitable for end-stage ... ...

Abstract	Primary sclerosing cholangitis (PSC) is an autoimmune cholangiopathy characterized by chronic inflammation of the biliary epithelium and periductal fibrosis, with no curative treatment available, and liver transplantation is inevitable for end-stage patients. Human placental mesenchymal stem cell (hpMSC)-derived exosomes have demonstrated the ability to prevent fibrosis, inhibit collagen production and possess immunomodulatory properties in autoimmune liver disease. Here, we prepared hpMSC-derived exosomes (Exo
Language	English
Publishing date	2024-02-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2650931-3
ISSN	2221-285X ; 1818-0876 ; 2221-285X
ISSN (online)	2221-285X
ISSN	1818-0876 ; 2221-285X
DOI	10.1016/j.ajps.2024.100889
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Serum vitamin C levels and risk of non-alcoholic fatty liver disease: results from a cross-sectional study and Mendelian randomization analysis.

Wu, Hui / Guo, Jiang-Long / Yao, Jing-Jiong / Yu, Jia-Jun / Xia, Run-Yu / Huang, Wei-Qing / Tang, Xuan / He, Guang-Ming

Frontiers in nutrition

2023 Volume 10, Page(s) 1162031

Abstract: Background and aims: Vitamin C, as an antioxidant, may play a role in the treatment of NAFLD. This research aimed to investigate the association of serum vitamin C levels with the risk of NAFLD and to further examine the causal relationship by Mendelian ...

Abstract	Background and aims: Vitamin C, as an antioxidant, may play a role in the treatment of NAFLD. This research aimed to investigate the association of serum vitamin C levels with the risk of NAFLD and to further examine the causal relationship by Mendelian randomization (MR) method. Methods: The cross-sectional study selected 5,578 participants of the National Health and Nutrition Examination Survey (NHANES), 2005-2006 and 2017-2018. The association of serum vitamin C levels with NAFLD risk was evaluated under a multivariable logistic regression model. A two-sample MR study, using genetic data from large-scale genome-wide association studies (GWAS) of serum vitamin C levels (52,014 individuals) and NAFLD (primary analysis: 1,483 cases /17,781 controls; secondary analysis: 1,908 cases/340,591 controls), was conducted to infer causality between them. The inverse-variance-weighted (IVW) was applied as the main method of MR analysis. A series of sensitivity analyzes were used to evaluate the pleiotropy. Results: In the cross-sectional study, results showed that Tertile 3 group (Tertile 3: ≥1.06 mg/dl) had a significantly lower risk (OR = 0.59, 95% CI: 0.48 ~ 0.74, Conclusion: Our MR study did not support a causal association between serum vitamin C levels and NAFLD risk. Further studies with greater cases are warranted to confirm our findings.
Language	English
Publishing date	2023-05-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2776676-7
ISSN	2296-861X
ISSN	2296-861X
DOI	10.3389/fnut.2023.1162031
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Article ; Online: Human Placental Mesenchymal Stem Cells Relieve Primary Sclerosing Cholangitis via Upregulation of TGR5 in Mdr2

Yao, Qigu / Chen, Wenyi / Yu, Yingduo / Gao, Feiqiong / Zhou, Jiahang / Wu, Jian / Pan, Qiaoling / Yang, Jinfeng / Zhou, Lingling / Yu, Jiong / Cao, Hongcui / Li, Lanjuan

Research (Washington, D.C.)

2023 Volume 6, Page(s) 207

Abstract: Primary sclerosing cholangitis (PSC) is a biliary disease accompanied by chronic inflammation of the liver and biliary stricture. Mesenchymal stem cells (MSCs) are used to treat liver diseases because of their immune regulation and regeneration-promoting ...

Abstract	Primary sclerosing cholangitis (PSC) is a biliary disease accompanied by chronic inflammation of the liver and biliary stricture. Mesenchymal stem cells (MSCs) are used to treat liver diseases because of their immune regulation and regeneration-promoting functions. This study was performed to explore the therapeutic potential of human placental MSCs (hP-MSCs) in PSC through the Takeda G protein-coupled receptor 5 (TGR5) receptor pathway. Liver tissues were collected from patients with PSC and healthy donors (
Language	English
Publishing date	2023-08-17
Publishing country	United States
Document type	Journal Article
ISSN	2639-5274
ISSN (online)	2639-5274
DOI	10.34133/research.0207
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression

Hongjia Zhang / Xueqian Sun / Zhanming Li / Tingting Liu / Fang Zhang / Xinyu Meng / Kaimi Li / Jianhua Xu / Wei He / Bo Jing / Tong Wang / Na Ni / Beibei Sun / Feng Yao / Yadi Wu / Qi Wang / Jing Du / Eugene Y. Chin / Binhua P. Zhou /

Ping Jiang / Lishun Wang / Jiong Deng

Genes and Diseases, Vol 11, Iss 3, Pp 100999- (2024)

2024

Keywords	Medicine (General) ; R5-920 ; Genetics ; QH426-470
Language	English
Publishing date	2024-05-01T00:00:00Z
Publisher	KeAi Communications Co., Ltd.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Characteristics of early gastric tumors with different differentiation and predictors of long-term outcomes after endoscopic submucosal dissection.

Zhu, Hong-Yi / Wu, Jie / Zhang, Yuan-Miao / Li, Fang-Lan / Yang, Jin / Qin, Bin / Jiang, Jiong / Zhu, Ning / Chen, Meng-Yao / Zou, Bai-Cang

World journal of gastroenterology

2024 Volume 30, Issue 14, Page(s) 1990–2005

Abstract: Background: Gastric cancer is a common malignant tumor of the digestive tract, and endoscopic submucosal dissection (ESD) is the preferred treatment for early-stage gastric cancer. The analysis of the epidemiological characteristics of gastric mucosal ... ...

Abstract	Background: Gastric cancer is a common malignant tumor of the digestive tract, and endoscopic submucosal dissection (ESD) is the preferred treatment for early-stage gastric cancer. The analysis of the epidemiological characteristics of gastric mucosal tumors with different differentiation degrees and the influencing factors of long-term ESD efficacy may have certain significance for revealing the development of gastric cancer and ESD. Aim: To analyze the features of gastric mucosal tumors at different differentiation levels, and to explore the prognostic factors of ESD. Methods: We retrospectively studied 301 lesions in 285 patients at The Second Affiliated Hospital of Xi'an Jiaotong University from 2014 to 2021, according to the latest Japanese guidelines (sixth edition), and divided them into low-grade intraepithelial neoplasia (LGIN), high-grade intraepithelial neoplasia (HGIN), and differentiated and undifferentiated early carcinoma. They are followed up by endoscopy, chest and abdominal computed tomography at 3, 6 and 12 months after ESD. We compared clinicopathologic characteristics, ESD efficacy, and complications with different degrees of differentiation, and analyzed the related factors associated with ESD. Results: HGIN and differentiated carcinoma patients were significantly older compared with LGIN patients ( Conclusion: Differentiations of gastric mucosal tumors have different epidemiological and endoscopic characteristics, which are closely related to the safety and efficacy of ESD.
MeSH term(s)	Humans ; Stomach Neoplasms/surgery ; Stomach Neoplasms/pathology ; Endoscopic Mucosal Resection/adverse effects ; Endoscopic Mucosal Resection/methods ; Male ; Female ; Middle Aged ; Retrospective Studies ; Gastric Mucosa/surgery ; Gastric Mucosa/pathology ; Gastric Mucosa/diagnostic imaging ; Aged ; Treatment Outcome ; Prognosis ; Adult ; Carcinoma in Situ/surgery ; Carcinoma in Situ/pathology ; Cell Differentiation ; Neoplasm Grading ; Gastroscopy/adverse effects ; Gastroscopy/methods ; Time Factors ; Neoplasm Staging ; Follow-Up Studies
Language	English
Publishing date	2024-02-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	2185929-2
ISSN	2219-2840 ; 1007-9327
ISSN (online)	2219-2840
ISSN	1007-9327
DOI	10.3748/wjg.v30.i14.1990
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Article ; Online: Aldh2 deficiency plays a dual role in lung tumorigenesis and tumor progression.

Zhang, Hongjia / Sun, Xueqian / Li, Zhanming / Liu, Tingting / Zhang, Fang / Meng, Xinyu / Li, Kaimi / Xu, Jianhua / He, Wei / Jing, Bo / Wang, Tong / Ni, Na / Sun, Beibei / Yao, Feng / Wu, Yadi / Wang, Qi / Du, Jing / Chin, Eugene Y / Zhou, Binhua P /

Jiang, Ping / Wang, Lishun / Deng, Jiong

Genes & diseases

2023 Volume 11, Issue 3, Page(s) 100999

Language	English
Publishing date	2023-06-24
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2821806-1
ISSN	2352-3042 ; 2352-3042
ISSN (online)	2352-3042
ISSN	2352-3042
DOI	10.1016/j.gendis.2023.04.030
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Red Blood Cell-Mimic Nanocatalyst Triggering Radical Storm to Augment Cancer Immunotherapy.

Li, Jiong / Wang, Sijia / Lin, Xinyi / Cao, Yanbing / Cai, Zhixiong / Wang, Jing / Zhang, Zhenxi / Liu, Xiaolong / Wu, Ming / Yao, Cuiping

Nano-micro letters

2022 Volume 14, Issue 1, Page(s) 57

Abstract: Red blood cells (RBCs) have recently emerged as promosing candidates for cancer treatment in terms of relieving tumor hypoxia and inducing oxidative damage against cancer cells, but they are still far from satisfactory due to their limited oxygen ... ...

Abstract	Red blood cells (RBCs) have recently emerged as promosing candidates for cancer treatment in terms of relieving tumor hypoxia and inducing oxidative damage against cancer cells, but they are still far from satisfactory due to their limited oxygen transport and reactive oxygen species generation rate in tumor tissue. Herein, artificial RBCs (designated FTP@RBCM) with radical storm production ability were developed for oncotherapy through multidimensional reactivity pathways of Fe-protoporphyrin-based hybrid metal-organic frameworks (FTPs, as the core), including photodynamic/chemodynamic-like, catalase-like and glutathione peroxidase-like activities. Meanwhile, owing to the advantages of long circulation abilities of RBCs provided by their cell membranes (RBCMs), FTP with a surface coated with RBCMs (FTP@RBCM) could enormously accumulate at tumor site to achieve remarkably enhanced therapeutic efficiency. Intriguingly, this ROS-mediated dynamic therapy was demonstrated to induce acute local inflammation and high immunogenic cancer death, which evoked a systemic antitumor immune response when combined with the newly identified T cell immunoglobulin and mucin-containing molecule 3 (Tim-3) checkpoint blockade, leading to not only effective elimination of primary tumors but also an abscopal effect of growth suppression of distant tumors. Therefore, such RBC-mimic nanocatalysts with multidimensional catalytic capacities might provide a promising new insight into synergistic cancer treatment.
Language	English
Publishing date	2022-02-05
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2642093-4
ISSN	2150-5551 ; 2150-5551
ISSN (online)	2150-5551
ISSN	2150-5551
DOI	10.1007/s40820-022-00801-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: TrichomeYOLO: A Neural Network for Automatic Maize Trichome Counting.

Xu, Jie / Yao, Jia / Zhai, Hang / Li, Qimeng / Xu, Qi / Xiang, Ying / Liu, Yaxi / Liu, Tianhong / Ma, Huili / Mao, Yan / Wu, Fengkai / Wang, Qingjun / Feng, Xuanjun / Mu, Jiong / Lu, Yanli

Plant phenomics (Washington, D.C.)

2023 Volume 5, Page(s) 24

Abstract: Plant trichomes are epidermal structures with a wide variety of functions in plant development and stress responses. Although the functional importance of trichomes has been realized, the tedious and time-consuming manual phenotyping process greatly ... ...

Abstract	Plant trichomes are epidermal structures with a wide variety of functions in plant development and stress responses. Although the functional importance of trichomes has been realized, the tedious and time-consuming manual phenotyping process greatly limits the research progress of trichome gene cloning. Currently, there are no fully automated methods for identifying maize trichomes. We introduce TrichomeYOLO, an automated trichome counting and measuring method that uses a deep convolutional neural network, to identify the density and length of maize trichomes from scanning electron microscopy images. Our network achieved 92.1% identification accuracy on scanning electron microscopy micrographs of maize leaves, which is much better performed than the other 5 currently mainstream object detection models, Faster R-CNN, YOLOv3, YOLOv5, DETR, and Cascade R-CNN. We applied TrichomeYOLO to investigate trichome variations in a natural population of maize and achieved robust trichome identification. Our method and the pretrained model are open access in Github (https://github.com/yaober/trichomecounter). We believe TrichomeYOLO will help make efficient trichome identification and help facilitate researches on maize trichomes.
Language	English
Publishing date	2023-02-28
Publishing country	United States
Document type	Journal Article
ISSN	2643-6515
ISSN (online)	2643-6515
DOI	10.34133/plantphenomics.0024
Database	MEDical Literature Analysis and Retrieval System OnLINE

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