LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 53

Search options

  1. Book: Demenzerkrankungen

    Adler, Georg / Mahlberg, Richard

    erkennen, behandeln und versorgen ; mit 50 Tabellen

    2009  

    Author's details R. Mahlberg ... (Hrsg.). Unter Mitarb. von Georg Adler
    Keywords Demenz
    Subject Anoia ; Dementia ; Chronische Verwirrtheit
    Language German
    Size XII, 342 S. : Ill., graph. Darst.
    Publisher Dt. Ärzte-Verl
    Publishing place Köln
    Publishing country Germany
    Document type Book
    HBZ-ID HT015797000
    ISBN 978-3-7691-0563-6 ; 3-7691-0563-X
    Database Catalogue ZB MED Medicine, Health

    More links

    Kategorien

  2. Article ; Online: Schlafstörungen im Alter.

    Mahlberg, Richard

    Deutsche medizinische Wochenschrift (1946)

    2016  Volume 141, Issue 16, Page(s) 1138–1140

    Abstract: Sleep disturbances are common in the elderly. Endogen regulation mechanisms are often unstable. Light treatment and melatonin are proved chronobiological interventions. Cataract surgery is effective to enhance the sleep-wake-rhythm.Mandibular advancement ...

    Title translation Sleep Disturbances in the Elderly.
    Abstract Sleep disturbances are common in the elderly. Endogen regulation mechanisms are often unstable. Light treatment and melatonin are proved chronobiological interventions. Cataract surgery is effective to enhance the sleep-wake-rhythm.Mandibular advancement devices are a reliable alternative to continuous positive air pressure (CPAP) in obstructive sleep apnea syndrome (OSAS).
    MeSH term(s) Aged ; Aged, 80 and over ; Aging ; Cataract ; Circadian Rhythm ; Humans ; Melatonin ; Sleep Apnea Syndromes ; Sleep Wake Disorders
    Chemical Substances Melatonin (JL5DK93RCL)
    Language German
    Publishing date 2016-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0042-107441
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Book ; Thesis: Störungen sakkadischer Augenbewegungen bei schizophren Erkrankten

    Mahlberg, Richard

    1998  

    Author's details vorgelegt von: Richard Mahlberg
    Language German
    Size II, 74 Bl., graph. Darst.
    Edition [Mikrofiche-Ausg.]
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Berlin, Freie Univ., Diss., 1998
    HBZ-ID HT013113207
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  4. Article: Running on Empty: Of Hypopinealism and Human Seasonality.

    Kunz, Dieter / Wahnschaffe, Amely / Kaempfe, Nina / Mahlberg, Richard

    Frontiers in pharmacology

    2021  Volume 12, Page(s) 681582

    Abstract: The pineal hormone melatonin is the natural transducer of the environmental light-dark signal to the body. Although the responsiveness to photoperiod is well-conserved in humans, only about 25 percent of the human population experiences seasonal changes ... ...

    Abstract The pineal hormone melatonin is the natural transducer of the environmental light-dark signal to the body. Although the responsiveness to photoperiod is well-conserved in humans, only about 25 percent of the human population experiences seasonal changes in behavior. As a consequence, humans seem to have adapted-at least partly-to the seasonal changes in day length. The aim of the study was to demonstrate that the individual melatonin deficit marker DOC (degree of pineal calcification) is related to variation of seasonal phenomena in humans. Out of 3,011 patients in which cranial computer tomography (cCT) was performed for diagnostic reasons, 97 consecutive "healthy" subjects (43 female, 54 male; age 18-68 yrs, mean ± SD: 35.0 ± 13.1) were included. Exclusion criteria were pathological finding in cCT, acute/chronic illness including alcohol/drug abuse, shift work, and medication, which are known to influence melatonin excretion. The degree of pineal calcification (DOC) was semiquantitatively determined using the previously validated method. The Seasonal Pattern Assessment Questionnaire (SPAQ) was performed in a telephone interview. Twenty-six subjects fulfilled the criteria for seasonal affective disorder (SAD) or subsyndromal (S) SAD. Seasonality was more pronounced in women than in men (SPAQ seasonality score: 7.8 ± 4.0 vs. 4.9 ± 4.5;
    Language English
    Publishing date 2021-10-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2021.681582
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: Schlafstörungen im Alter

    Mahlberg, Richard

    DMW - Deutsche Medizinische Wochenschrift

    2016  Volume 141, Issue 16, Page(s) 1138–1140

    Abstract: Schlafstörungen sind ein häufiges Gesundheitsproblem im Alter. Die endogene Regulierung von Müdigkeit ist bei älteren Menschen häufig gestört. Mit Licht und Melatonin stehen chronobiologische Interventionsmöglichkeiten zur Verfügung. Eine ... ...

    Abstract Schlafstörungen sind ein häufiges Gesundheitsproblem im Alter. Die endogene Regulierung von Müdigkeit ist bei älteren Menschen häufig gestört. Mit Licht und Melatonin stehen chronobiologische Interventionsmöglichkeiten zur Verfügung. Eine Kataraktoperation trägt zur Verbesserung der Wahrnehmung des Hell-Dunkel-Kontrastes und damit zur Schlagregulation bei. Eine weitere häufige Störung im Alter ist das obstruktive Schlafapnoesyndrom. Als Alternative zur kontinuierliche Überdruckbeatmung Beatmung (CPAP) bieten sich Protrusionsschienen an.
    Keywords Schlaf ; ältere Menschen ; zirkadianer Rhythmus ; Licht ; Melatonin ; Schlafapnoesyndrom ; CPAP-Beatmung ; Protrusionsschiene ; sleep ; elderly ; circadian rhythm ; light treatment ; melatonin ; Obstructive Sleep Apnea Syndrome (OSAS) ; Continuous Positive Air Pressure (CPAP) ; mandibular advancement device
    Language German
    Publishing date 2016-08-01
    Publisher © Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 200446-x
    ISSN 1439-4413 ; 0012-0472
    ISSN (online) 1439-4413
    ISSN 0012-0472
    DOI 10.1055/s-0042-107441
    Database Thieme publisher's database

    More links

    Kategorien

  6. Article ; Online: The investigation and differential diagnosis of dementias.

    Mahlberg, Richard

    Deutsches Arzteblatt international

    2010  Volume 107, Issue 39, Page(s) 675–676

    MeSH term(s) Brain/pathology ; Brain/physiopathology ; Cognition Disorders/diagnosis ; Cognition Disorders/physiopathology ; Dementia/diagnosis ; Dementia/physiopathology ; Diagnosis, Differential ; Diagnostic Imaging ; Early Diagnosis ; Humans ; International Classification of Diseases ; Mental Status Schedule ; Neuropsychological Tests ; Spinal Puncture
    Language English
    Publishing date 2010-10-01
    Publishing country Germany
    Document type Comment ; Editorial
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.2010.0675
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Book: Alzheimer: was tun, wenn die Krankheit beginnt?

    Niemann-Mirmehdi, Mechthild / Mahlberg, Richard

    Alles über Diagnose und Therapie ; wie Sie sich auf ein verändertes Leben einstellen ; ein einfühlsamer Ratgeber für Betroffene und Angehörige

    2003  

    Author's details Mechthild Niemann-Mirmehdi ; Richard Mahlberg
    Keywords Alzheimerkrankheit
    Subject Alzheimer-Krankheit ; Alzheimersche Krankheit ; Alzheimer-Demenz ; Morbus Alzheimer ; Greisenblödsinn ; Alzheimer's Disease
    Language German
    Size 135 S. : Ill.
    Publisher Trias
    Publishing place Stuttgart
    Publishing country Germany
    Document type Book
    HBZ-ID HT013776055
    ISBN 3-8304-3034-5 ; 978-3-8304-3034-6
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  8. Article ; Online: A two-part, double-blind, placebo-controlled trial of exogenous melatonin in REM sleep behaviour disorder.

    Kunz, Dieter / Mahlberg, Richard

    Journal of sleep research

    2010  Volume 19, Issue 4, Page(s) 591–596

    Abstract: Rapid eye movement (REM) sleep behaviour disorder (RBD) has been suggested to predict the development of neurodegenerative disorders. Patients with RBD are acting out dream behaviour associated with loss of normal muscle atonia of REM sleep. The aim of ... ...

    Abstract Rapid eye movement (REM) sleep behaviour disorder (RBD) has been suggested to predict the development of neurodegenerative disorders. Patients with RBD are acting out dream behaviour associated with loss of normal muscle atonia of REM sleep. The aim of the present study was to confirm that exogenous melatonin improves RBD. Eight consecutively recruited males (mean age 54 years) with a polysomnographically (PSG) confirmed diagnosis of RBD were included in a two-part, randomized, double-blind, placebo-controlled cross-over study. Patients received placebo and 3 mg of melatonin daily in a cross-over design, administered between 22:00 h and 23:00 h over a period of 4 weeks. PSG recordings were performed in all patients at baseline, at the end of Part I of the trial and at the end of Part II of the trial. Compared to baseline, melatonin significantly reduced the number of 30-s REM sleep epochs without muscle atonia (39% versus 27%; P = 0.012), and led to a significant improvement in clinical global impression (CGI: 6.1 versus 4.6; P = 0.024). Interestingly, the number of REM sleep epochs without muscle atonia remained lower in patients who took placebo during Part II after having received melatonin in Part I (-16% compared to baseline; P = 0.043). In contrast, patients who took placebo during Part I showed improvements in REM sleep muscle atonia only during Part II (i.e. during melatonin treatment). The data suggest that melatonin might be a second useful agent besides clonazepam in the treatment of RBD.
    MeSH term(s) Adult ; Aged ; Central Nervous System Depressants/therapeutic use ; Double-Blind Method ; Humans ; Male ; Melatonin/therapeutic use ; Middle Aged ; Polysomnography/drug effects ; REM Sleep Behavior Disorder/drug therapy ; Sleep/drug effects ; Sleep, REM/drug effects ; Treatment Outcome
    Chemical Substances Central Nervous System Depressants ; Melatonin (JL5DK93RCL)
    Language English
    Publishing date 2010-12
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1122722-9
    ISSN 1365-2869 ; 0962-1105
    ISSN (online) 1365-2869
    ISSN 0962-1105
    DOI 10.1111/j.1365-2869.2010.00848.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Decreased Verbal Learning but not Recognition Performance in Alcohol-dependent Individuals During Early Abstinence.

    Daig, Isolde / Mahlberg, Richard / Stethin, Julia / Schroeder, Franziska / Wrase, Jana / Knoll, Nina / Bschor, Tom / Esser, Guenter / Heinz, Andreas / Kienast, Thorsten

    Irish journal of psychological medicine

    2018  Volume 29, Issue 2, Page(s) 96–101

    Abstract: Objective: Alcoholism ultimately leads to impairment of memory and other cognitive functions. This can interfere with treatment, if cognitively impaired alcohol-dependent individuals have difficulties recalling and implementing skills acquired during ... ...

    Abstract Objective: Alcoholism ultimately leads to impairment of memory and other cognitive functions. This can interfere with treatment, if cognitively impaired alcohol-dependent individuals have difficulties recalling and implementing skills acquired during therapy. We investigate if alcohol-dependent individuals without clinically apparent withdrawal symptoms may still be impaired in higher-order cognitive functions.
    Methods: Thirty-four alcohol-dependent patients and 20 matched healthy controls were tested with the Verbal Learning and Memory Test which includes seven measurement points. The test comprises free recall, free recall after distraction and after 30 minute delay, and a word recognition task. Testing was performed between day seven and day 10 after the beginning of abstinence, when clinical withdrawal symptoms had ceased.
    Results: Compared to healthy controls, alcohol-dependent patients performed worse in free recall after delay, but not in word recognition. Healthy controls showed a more linear progression of improvement in verbal memory performance. Overall, alcohol-dependent individuals showed reduced verbal learning efficiency. The extent of impaired recall after distraction was positively associated (one-tailed test) with history of delirium (r=0.34, p=0.04), seizures (r=0.46, p=0.01), and years since diagnosis for alcohol dependency (r=0.39, p=0.01).
    Conclusions: Our results provide evidence that unmedicated alcohol-dependent patients without obvious withdrawal symptoms had impaired verbal recall, but normal recognition performance, at seven to 10 days after onset of abstinence. This deficit may deteriorate treatment outcomes due to poorer implementation of skills newly-learned during this time period.
    Language English
    Publishing date 2018-09-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2118675-3
    ISSN 2051-6967 ; 0790-9667
    ISSN (online) 2051-6967
    ISSN 0790-9667
    DOI 10.1017/S0790966700017377
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article: Veränderungen der Zeitbeurteilung im Alter.

    Mahlberg, Richard / Bschor, Tom

    Psychiatrische Praxis

    2007  Volume 34, Issue 3, Page(s) 117–121

    Abstract: Objective: Time perception can be divided into two processes: time experience and time judgement. Although there have been frequent reports of changes in these two processes with increasing age, none of these changes has been demonstrated using ... ...

    Title translation Alterations of time judgement with age.
    Abstract Objective: Time perception can be divided into two processes: time experience and time judgement. Although there have been frequent reports of changes in these two processes with increasing age, none of these changes has been demonstrated using objective measures.
    Methods: We evaluated time judgement by employing time estimation, time production, and time reproduction tasks in 33 healthy subjects of all age groups. In addition, we used the Trail-Making Test to measure attentional performance.
    Results: For both time estimation and time reproduction, we found positive correlations between length of time interval and age (overestimation). After we calculated partial correlations controlling for the results of the Trail-Making Test, the age-related changes we initially observed in the time estimation task disappeared, but the age-related changes seen in the time reproduction task remained significant.
    Conclusions: Considering the Scalar Timing Theory and the Attentional Gate Theory, our findings indicated that age-related effects on time estimation may be due to attentional factors. In contrast, the age-related changes seen in the time reproduction task may be due to disturbances in working memory function.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Aging/psychology ; Attention ; Female ; Humans ; Judgment ; Male ; Memory, Short-Term ; Middle Aged ; Neuropsychological Tests ; Perceptual Distortion ; Statistics as Topic ; Time Perception ; Trail Making Test
    Language German
    Publishing date 2007-04
    Publishing country Germany
    Document type English Abstract ; Journal Article
    ZDB-ID 124981-2
    ISSN 1439-0876 ; 0303-4259
    ISSN (online) 1439-0876
    ISSN 0303-4259
    DOI 10.1055/s-2006-951972
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top