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  1. AU=Sirven J
  2. AU=Bramwell Byrom
  3. AU=Decaris Martin L AU=Decaris Martin L
  4. AU="Palanisamy, Navaneethan"
  5. AU="Ruiz, R"
  6. AU="Kabir, Mahvish"
  7. AU="Mu, Erzhen"
  8. AU="Maghoul, Shahin"
  9. AU=Elder George
  10. AU="Lefever, S."
  11. AU="St Sauver, Jennifer L"
  12. AU="McDonnell, David"
  13. AU="Costa, Carolina Oliveira"
  14. AU="Meriggi, Antonio"
  15. AU=Hadjipavlou George
  16. AU="Burchard, Rene"
  17. AU="Mohammad Tolouei"
  18. AU="Sugimachi, Keishi"
  19. AU="Renziehausen, Laura"
  20. AU="De Andrés-Laguillo, Macarena"
  21. AU="Sheila V. Kusnoor"
  22. AU="Aydoğdu, İsmet"
  23. AU=Fried Jonathan E
  24. AU="April C. Roslani"
  25. AU="Scott, Jeffrey F"
  26. AU=Piscaglia Anna Chiara AU=Piscaglia Anna Chiara
  27. AU="Ziya Bozkurt"
  28. AU="Morris, Michael A."
  29. AU="Low, Keat"
  30. AU="Zick, G."
  31. AU=Miles Alexander
  32. AU="Orzan, Fulvio"
  33. AU="Shruti A. Anant"
  34. AU="Jin, Hong-Wei"
  35. AU="Gonzalez, Louis"
  36. AU=Torres Victor J.
  37. AU="Manning, Nyla"
  38. AU="Sindkar, Anushka"
  39. AU=Rodieux Frdrique
  40. AU="Tote, Sachin"

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  1. Artikel: Mechanical stirring: Novel engineering approach for in situ spectroscopic analysis of melt at high temperature.

    Belrhiti, Y / Albaric, M / Benmansour, M / Sirven, J-B / Chabli, A

    Heliyon

    2024  Band 10, Heft 4, Seite(n) e25626

    Abstract: This paper proposes a novel engineering approach to control molten metals at high temperatures considering the industrial environment of such materials. To reduce analysis time and cost, in-line analysis techniques are more advantageous as they provide ... ...

    Abstract This paper proposes a novel engineering approach to control molten metals at high temperatures considering the industrial environment of such materials. To reduce analysis time and cost, in-line analysis techniques are more advantageous as they provide real-time information about melt composition. For this reason, recent research works focus on the development of new devices based on LIBS (Laser Induced Breakdown Spectroscopy). These devices allowed for analyzing impurities inside molten metals with great performance. However, improvements related to the immersion probe conception are still required. Indeed, the previous design used bubbling inside the melt, leading to spatial instabilities of the surface analyzed by LIBS. The solution presented here is mechanical stirring by innovative rotary blades which will be a part of an immersion LIBS probe. Their rotation will generate a representative, renewed, and stable surface that will be targeted by spectroscopic techniques in general and particularly by LIBS laser for molten metal monitoring at high temperatures. This solution was validated using experimental tests based on particle imaging velocimetry (PIV) in water at room temperature and then applied to silicon melt at high temperatures. To do so, it was necessary to design a system that allows the introduction of the blade in the melt and controls its rotation.
    Sprache Englisch
    Erscheinungsdatum 2024-02-05
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2024.e25626
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Comment on: Failure to use new breakthrough treatments for epilepsy.

    Peters, Jurriaan M / Becker, Danielle A / Verma, Amit / Sirven, Joseph

    Epilepsia

    2023  Band 64, Heft 11, Seite(n) 3109–3110

    Mesh-Begriff(e) Humans ; Epilepsy/drug therapy ; Seizures
    Sprache Englisch
    Erscheinungsdatum 2023-09-05
    Erscheinungsland United States
    Dokumenttyp Letter ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 216382-2
    ISSN 1528-1167 ; 0013-9580
    ISSN (online) 1528-1167
    ISSN 0013-9580
    DOI 10.1111/epi.17764
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Treatment of Seizure Clusters in Epilepsy: A Narrative Review on Rescue Therapies.

    Becker, Danielle A / Wheless, James W / Sirven, Joseph / Tatum, William O / Rabinowicz, Adrian L / Carrazana, Enrique

    Neurology and therapy

    2023  Band 12, Heft 5, Seite(n) 1439–1455

    Abstract: Epilepsy is a common neurological disorder in the United States, affecting approximately 1.2% of the population. Some people with epilepsy may experience seizure clusters, which are acute repetitive seizures that differ from the person's usual seizure ... ...

    Abstract Epilepsy is a common neurological disorder in the United States, affecting approximately 1.2% of the population. Some people with epilepsy may experience seizure clusters, which are acute repetitive seizures that differ from the person's usual seizure pattern. Seizure clusters are unpredictable, are emotionally burdensome to patients and caregivers (including care partners), and require prompt treatment to prevent progression to serious outcomes, including status epilepticus and associated morbidity (e.g., lacerations, fractures due to falls) and mortality. Rescue medications for community use can be administered to terminate a seizure cluster, and benzodiazepines are the cornerstone of rescue treatment. Despite the effectiveness of benzodiazepines and the importance of a rapid treatment approach, as many as 80% of adult patients do not use rescue medication to treat seizure clusters. This narrative review provides an update on rescue medications used for treatment of seizure clusters, with an emphasis on clinical development and study programs for diazepam rectal gel, midazolam nasal spray, and diazepam nasal spray. Results from long-term clinical trials have shown that treatments for seizure clusters are effective. Intranasal benzodiazepines provide ease of use and patient and caregiver satisfaction in pediatric and adult patients. Adverse events attributed to acute rescue treatments have been characterized as mild to moderate, and no reports of respiratory depression have been attributed to treatment in long-term safety studies. The implementation of an acute seizure action plan to facilitate optimal use of rescue medications provides an opportunity for improved management of seizure clusters, allowing those affected to resume normal daily activities more quickly.
    Sprache Englisch
    Erscheinungsdatum 2023-06-21
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article ; Review
    ISSN 2193-8253
    ISSN 2193-8253
    DOI 10.1007/s40120-023-00515-3
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Looks can be deceptive: A primary generalized epilepsy mimicking a lesional focal-reflex epilepsy.

    Cheng, Christopher / Sirven, Joseph I / Ryan, Daniel J / Feyissa, Anteneh M

    Seizure

    2021  Band 91, Seite(n) 114–116

    Mesh-Begriff(e) Electroencephalography ; Epilepsies, Partial ; Epilepsy, Generalized ; Epilepsy, Reflex/diagnosis ; Humans
    Sprache Englisch
    Erscheinungsdatum 2021-06-10
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1137610-7
    ISSN 1532-2688 ; 1059-1311
    ISSN (online) 1532-2688
    ISSN 1059-1311
    DOI 10.1016/j.seizure.2021.06.005
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: FRAILTY, SARCOPENIA AND LONG TERM CARE UTILIZATION IN OLDER POPULATIONS: A SYSTEMATIC REVIEW.

    Roquebert, Q / Sicsic, J / Santos-Eggimann, B / Sirven, N / Rapp, T

    The Journal of frailty & aging

    2021  Band 10, Heft 3, Seite(n) 272–280

    Abstract: This systematic literature review documents the link between frailty or sarcopenia, conceptualized as dimensions of physical health, and the use of long-term care services by older individuals. Long-term care services include formal and informal care ... ...

    Abstract This systematic literature review documents the link between frailty or sarcopenia, conceptualized as dimensions of physical health, and the use of long-term care services by older individuals. Long-term care services include formal and informal care provided at home as well as in institutions. A systematic review was performed according to PRISMA requirements using the following databases: PubMed-Medline, Embase, CINAHL, Web of Science, and Academic Search Premier. We included all quantitative studies published in English between January 2000 and December 2018 focusing on individuals aged 50 or more, using a relevant measurement of sarcopenia or physical frailty and a long-term care related outcome. A quality assessment was carried out using the questionnaire established by the Good Practice Task Force Report of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Five subsets of long-term care outcome were considered: 1/ nursing home placement (NHP), 2/ nursing home short stay (NHSS), 3/ formal personal care (FPC), 4/ formal home help (FHH), 5/ informal care (IC). Out of 1943 studies, 17 were finally included in the review. With some studies covering several LTC outcomes, frailty and / or sarcopenia were associated with increased LTC use in 17 out of 26 cases (NHP: 5/6, NHSS: 3/4, FPC: 5/7, FHH: 1/4, IC: 3/5) The association was not consistent in 5 cases (NHP: 1/6, NHSS: 1/4, FPC: 2/7, FHH: 0/4, IC: 1/5) and the association was either not significant or the results inconclusive in the remaining 9 cases. Overall, while results on sarcopenia are scarce, evidence support a positive association between frailty and LTC use. The evidence is stronger for the association of physical frailty with nursing home placement / short stay as well as on FPC. There is less (more heterogeneous) evidence regarding the correlation between physical frailty and FHH or IC use. Results need to be confirmed by more advanced statistical methods or design based on longitudinal data.
    Mesh-Begriff(e) Aged ; Frailty/epidemiology ; Humans ; Long-Term Care ; Nursing Homes ; Outcome Assessment, Health Care ; Sarcopenia/epidemiology
    Sprache Englisch
    Erscheinungsdatum 2021-06-04
    Erscheinungsland France
    Dokumenttyp Journal Article ; Systematic Review
    ZDB-ID 2856228-8
    ISSN 2273-4309 ; 2260-1341
    ISSN (online) 2273-4309
    ISSN 2260-1341
    DOI 10.14283/jfa.2021.7
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: The silent gap between epilepsy surgery evaluations and clinical practice guidelines.

    Sirven, J I

    European journal of neurology

    2010  Band 17, Heft 4, Seite(n) 522–523

    Mesh-Begriff(e) Brain/physiopathology ; Brain/surgery ; Epilepsy/diagnosis ; Epilepsy/epidemiology ; Epilepsy/physiopathology ; Epilepsy/surgery ; Humans ; Patient Selection ; Practice Guidelines as Topic ; Sweden
    Sprache Englisch
    Erscheinungsdatum 2010-04
    Erscheinungsland England
    Dokumenttyp Comment ; Editorial
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/j.1468-1331.2009.02892.x
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel ; Online: Comment on "Intranasal midazolam versus intravenous/rectal benzodiazepines for acute seizure control in children: A systematic review and meta-analysis".

    Wheless, James / Peters, Jurriaan / Misra, Sunita N / Becker, Danielle / Rabinowicz, Adrian L / Sirven, Joseph / Carrazana, Enrique

    Epilepsy & behavior : E&B

    2022  Band 128, Seite(n) 108550

    Mesh-Begriff(e) Administration, Intranasal ; Benzodiazepines/therapeutic use ; Child ; Diazepam/therapeutic use ; Humans ; Seizures/drug therapy ; Status Epilepticus/drug therapy
    Chemische Substanzen Benzodiazepines (12794-10-4) ; Diazepam (Q3JTX2Q7TU)
    Sprache Englisch
    Erscheinungsdatum 2022-01-19
    Erscheinungsland United States
    Dokumenttyp Letter ; Comment
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2021.108550
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Generation of Rossby waves off the Cape Verde Peninsula

    J. Sirven / J. Mignot / M. Crépon

    Ocean Science, Vol 15, Pp 1667-

    the role of the coastline

    2019  Band 1690

    Abstract: In December 2002 and January 2003 satellite observations of chlorophyll showed a strong coastal signal along the west African coast between 10 and 22 ∘ N. In addition, a wavelike pattern with a wavelength of about 750 km was observed from 20 December ... ...

    Abstract In December 2002 and January 2003 satellite observations of chlorophyll showed a strong coastal signal along the west African coast between 10 and 22 ∘ N. In addition, a wavelike pattern with a wavelength of about 750 km was observed from 20 December 2002 and was detectable for 1 month in the open sea, south-west of the Cape Verde Peninsula. Such a pattern suggests the existence of a locally generated Rossby wave which slowly propagated westward during this period. This hypothesis was confirmed by analysing sea surface height provided by satellite altimeter during this period. To decipher the mechanisms at play, a numerical study based on a reduced-gravity shallow-water model has first been conducted. A wind burst, broadly extending over the region where the offshore oceanic signal is observed, is applied for 5 d. A Kelvin wave quickly develops along the northern edge of the cape, then propagates and leaves the area in a few days. Simultaneously, a Rossby wave whose characteristics seem similar to the observed pattern forms and slowly propagates westward. The existence of the peninsula limits the extent of the wave to the north. The spatial extent of the wind burst determines the extent of the response and correspondingly the timescale of the phenomenon (about 100 d in the present case). When the wind burst has a large zonal and small meridional extent, the behaviour of a wave to the north of the peninsula differs from that to the south. These results are corroborated and completed by an analytical study of a linear reduced-gravity model using a non-Cartesian coordinate system. This system is introduced to evaluate the potential impact of the coastline shape. The analytical computations confirm that a period of around 100 d can be associated with the observed wave considering the value of the wavelength; they also show that the role of the coastline remains moderate at such timescales. By contrast, when the period becomes shorter (smaller than 20–30 d), the behaviour of the waves is modified because of the shape ...
    Schlagwörter Geography. Anthropology. Recreation ; G ; Environmental sciences ; GE1-350
    Thema/Rubrik (Code) 551
    Sprache Englisch
    Erscheinungsdatum 2019-12-01T00:00:00Z
    Verlag Copernicus Publications
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Risk factors for preoperative and postoperative seizures in patients with glioblastoma according to the 2021 World Health Organization classification.

    Feyissa, Anteneh M / Sanchez-Boluarte, Sofia S / Moniz-Garcia, Diogo / Chaichana, Kaisorn L / Sherman, Wendy J / Freund, Brin E / Tatum, William O / Middlebrooks, Erik H / Sirven, Joseph I / Quinones-Hinojosa, Alfredo

    Seizure

    2023  Band 112, Seite(n) 26–31

    Abstract: Objective: To identify risk factors for developing glioblastoma (GBM) related preoperative (PRS) and postoperative seizures (POS). Also, we aimed to analyze the impact of PRS and POS on survival in a GBM cohort according to the revised 2021 WHO glioma ... ...

    Abstract Objective: To identify risk factors for developing glioblastoma (GBM) related preoperative (PRS) and postoperative seizures (POS). Also, we aimed to analyze the impact of PRS and POS on survival in a GBM cohort according to the revised 2021 WHO glioma classification.
    Methods: We performed a single-center retrospective cohort study of patients with GBM (according to the 2021 World Health Organization Classification) treated at Mayo Clinic Florida between January 2018 and July 2022. Seizures were stratified into preoperative seizures (PRS) and postoperative seizures (POS, >7 days after surgery). Associations between patients' characteristics and overall survival with PRS and POS were assessed.
    Results: One hundred nineteen adults (mean =60.9 years), 49 (41.2 %) females, were identified. The rates of PRS and POS in the cohort were 35.3 % (n = 42) and 37.8 % (n = 45), respectively. Patients with PRS were younger (p = 0.035) and were likely to undergo intraoperative electrocorticography. The incidence of PRS (p = 0.049) and POS (p<0.001) was lower among patients with tumors located in the occipital location. PRS increased the risk of POS after adjusting for age and sex (RR: 2.59, CI = 1.44-4.65, p = 0.001). There was no association between PRS or POS and other patient-related factors, including several tumor molecular markers (TMMs) examined. PRS (p = 0.036), POS (p<0.001), and O6-Methylguanine-DNA Methyltransferase (MGMT) promotor methylation status (p = 0.032) were associated with longer survival time.
    Conclusions: PRS and POS are associated with non-occipital tumor location and longer survival time in patients with GBM. While younger ages predicted PRS, PRS predicted POS. Well-designed prospective studies with larger sample sizes are needed to clarify the influence of TMMs in the genesis of epileptic seizures in patients with GBM.
    Mesh-Begriff(e) Adult ; Female ; Humans ; Male ; Glioblastoma/complications ; Glioblastoma/surgery ; Retrospective Studies ; Prospective Studies ; Brain Neoplasms/complications ; Brain Neoplasms/surgery ; Brain Neoplasms/genetics ; Seizures/complications ; Risk Factors ; Prognosis ; DNA Methylation
    Sprache Englisch
    Erscheinungsdatum 2023-09-17
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 1137610-7
    ISSN 1532-2688 ; 1059-1311
    ISSN (online) 1532-2688
    ISSN 1059-1311
    DOI 10.1016/j.seizure.2023.09.013
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Buch ; Online: Generation of Rossby waves off the Cape Verde Peninsula

    Sirven, Jérôme / Mignot, Juliette / Crépon, Michel

    eISSN: 1812-0792

    the role of the coastline

    2019  

    Abstract: In December 2002 and January 2003 satellite observations of chlorophyll showed a strong coastal signal along the west African coast between 10 and 22 ∘ N. In addition, a wavelike pattern with a wavelength of about 750 km was observed from 20 December ... ...

    Abstract In December 2002 and January 2003 satellite observations of chlorophyll showed a strong coastal signal along the west African coast between 10 and 22 ∘ N. In addition, a wavelike pattern with a wavelength of about 750 km was observed from 20 December 2002 and was detectable for 1 month in the open sea, south-west of the Cape Verde Peninsula. Such a pattern suggests the existence of a locally generated Rossby wave which slowly propagated westward during this period. This hypothesis was confirmed by analysing sea surface height provided by satellite altimeter during this period. To decipher the mechanisms at play, a numerical study based on a reduced-gravity shallow-water model has first been conducted. A wind burst, broadly extending over the region where the offshore oceanic signal is observed, is applied for 5 d. A Kelvin wave quickly develops along the northern edge of the cape, then propagates and leaves the area in a few days. Simultaneously, a Rossby wave whose characteristics seem similar to the observed pattern forms and slowly propagates westward. The existence of the peninsula limits the extent of the wave to the north. The spatial extent of the wind burst determines the extent of the response and correspondingly the timescale of the phenomenon (about 100 d in the present case). When the wind burst has a large zonal and small meridional extent, the behaviour of a wave to the north of the peninsula differs from that to the south. These results are corroborated and completed by an analytical study of a linear reduced-gravity model using a non-Cartesian coordinate system. This system is introduced to evaluate the potential impact of the coastline shape. The analytical computations confirm that a period of around 100 d can be associated with the observed wave considering the value of the wavelength; they also show that the role of the coastline remains moderate at such timescales. By contrast, when the period becomes shorter (smaller than 20–30 d), the behaviour of the waves is modified because of the shape of the coast. South of the peninsula, a narrow band of sea isolated from the rest of the ocean by two critical lines appears. Its meridional extent is about 100 km and Rossby waves could propagate there towards the coast.
    Thema/Rubrik (Code) 551
    Sprache Englisch
    Erscheinungsdatum 2019-12-13
    Erscheinungsland de
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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