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  1. Article ; Online: Genetic and Other Determinants for the Severity of Coccidioidomycosis: A Clinician's Perspective.

    Galgiani, John N / Hsu, Amy P / Powell, Daniel A / Vyas, Jatin M / Holland, Steven M

    Journal of fungi (Basel, Switzerland)

    2023  Volume 9, Issue 5

    Abstract: The endemic fungal infection, coccidioidomycosis, occurs after inhalation of one or very ... ...

    Abstract The endemic fungal infection, coccidioidomycosis, occurs after inhalation of one or very few
    Language English
    Publishing date 2023-05-11
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof9050554
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Differential skin immune responses in mice intradermally infected with

    Datta, Abhishek / Das, Diprasom / Nett, Jeniel E / Vyas, Jatin M / Lionakis, Michail S / Thangamani, Shankar

    Microbiology spectrum

    2023  Volume 11, Issue 6, Page(s) e0221523

    Abstract: Importance: Candida ... ...

    Abstract Importance: Candida auris
    MeSH term(s) Animals ; Mice ; Candida albicans ; Candida ; Candida auris ; Disease Outbreaks ; Immunity ; Antifungal Agents
    Chemical Substances Antifungal Agents
    Language English
    Publishing date 2023-10-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.02215-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The first line of defense: effector pathways of anti-fungal innate immunity.

    Ward, Rebecca A / Vyas, Jatin M

    Current opinion in microbiology

    2020  Volume 58, Page(s) 160–165

    Abstract: The innate immune system is critical to proper host defense against fungal pathogens, which is highlighted by increased susceptibility to invasive disease in immunocompromised patients. Innate cells (e.g. macrophages, neutrophils, dendritic cells, ... ...

    Abstract The innate immune system is critical to proper host defense against fungal pathogens, which is highlighted by increased susceptibility to invasive disease in immunocompromised patients. Innate cells (e.g. macrophages, neutrophils, dendritic cells, eosinophils) are equipped with intricate cell machinery to detect invading fungi and facilitate fungal killing, recruit additional immune cells, and direct the adaptive immune system responses. Understanding the mechanisms that govern a protective response will enable the development of novel treatment strategies. This review focuses on recent insights of signaling and regulation of C-type lectin receptors and their effector mechanisms enabling an effective host antifungal immunity.
    MeSH term(s) Animals ; Fungi/genetics ; Fungi/physiology ; Humans ; Immunity, Innate ; Macrophages/immunology ; Mycoses/genetics ; Mycoses/immunology ; Mycoses/microbiology ; Neutrophils/immunology
    Language English
    Publishing date 2020-11-17
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1418474-6
    ISSN 1879-0364 ; 1369-5274
    ISSN (online) 1879-0364
    ISSN 1369-5274
    DOI 10.1016/j.mib.2020.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5514: Show issues Location:
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  4. Article ; Online: Case 9-2022: A 56-Year-Old Woman with Fever, Myalgias, Diarrhea, and Cough.

    Vyas, Jatin M / Castle, Alison C / Bourgouin, Patrick P / Turbett, Sarah E

    The New England journal of medicine

    2022  Volume 386, Issue 12, Page(s) 1166–1174

    MeSH term(s) Anaplasma phagocytophilum/isolation & purification ; Anaplasmosis/complications ; Anaplasmosis/diagnosis ; Bias ; COVID-19/diagnosis ; Cough/etiology ; Decision Making ; Diagnosis, Differential ; Diarrhea/etiology ; Female ; Fever/etiology ; Humans ; Lung/diagnostic imaging ; Lung/pathology ; Middle Aged ; Myalgia/etiology ; Symptom Assessment
    Language English
    Publishing date 2022-03-23
    Publishing country United States
    Document type Case Reports ; Clinical Conference ; Journal Article
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMcpc2115846
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Cross-kingdom anti-inflammatory effects of fungal melanin on airway epithelium by post-translational blockade of chemokine secretion.

    Reedy, Jennifer L / Crossen, Arianne J / Ward, Rebecca A / Reardon, Christopher M / Harding, Hannah Brown / Basham, Kyle J / Rajagopal, Jayaraj / Vyas, Jatin M

    bioRxiv : the preprint server for biology

    2023  

    Abstract: Respiratory infections caused by the human fungal pathogens, ...

    Abstract Respiratory infections caused by the human fungal pathogens,
    Language English
    Publishing date 2023-03-29
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.03.28.534632
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Single-Cell Transcriptomes, Lineage, and Differentiation of Functional Airway Microfold Cells.

    Surve, Manalee V / Lin, Brian / Reedy, Jennifer L / Crossen, Arianne J / Xu, Anthony / Klein, Bruce S / Vyas, Jatin M / Rajagopal, Jayaraj

    American journal of respiratory cell and molecular biology

    2023  Volume 69, Issue 6, Page(s) 698–701

    MeSH term(s) Transcriptome/genetics ; M Cells ; Cell Differentiation/physiology ; Respiratory System ; Cell Lineage/genetics
    Language English
    Publishing date 2023-12-07
    Publishing country United States
    Document type Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 1025960-0
    ISSN 1535-4989 ; 1044-1549
    ISSN (online) 1535-4989
    ISSN 1044-1549
    DOI 10.1165/rcmb.2023-0292LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2851: Show issues Location:
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  7. Article: Single Cell Transcriptomes, Lineage, and Differentiation of Functional Airway Microfold Cells.

    Surve, Manalee V / Lin, Brian / Reedy, Jennifer L / Crossen, Arianne J / Xu, Anthony / Klein, Bruce S / Vyas, Jatin M / Rajagopal, Jayaraj

    bioRxiv : the preprint server for biology

    2023  

    Abstract: ... transcriptomes of airway Microfold (M) cells, whose gut counterparts have long been known for their antigen ... governing the differentiation and functions of airway M cells are largely unknown. Here, we shed light ... on the pathways of airway M cell differentiation, establish their lineage, and identify a functional M cell ...

    Abstract The airway epithelium is frequently exposed to pathogens and allergens, but the cells that are responsible for sampling these inhaled environmental agents have not been fully defined. Thus, there is a critical void in our understanding of how luminal antigens are delivered to the immune cells that drive the appropriate immune defenses against environmental assaults. In this study, we report the first single cell transcriptomes of airway Microfold (M) cells, whose gut counterparts have long been known for their antigen sampling abilities. Given their very recent discovery in the lower respiratory airways, the mechanisms governing the differentiation and functions of airway M cells are largely unknown. Here, we shed light on the pathways of airway M cell differentiation, establish their lineage, and identify a functional M cell-specific endocytic receptor, the complement receptor 2 (CR2). Lastly, we demonstrate that airway M cells can endocytose
    Language English
    Publishing date 2023-08-07
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.08.06.552176
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Diagnostic Reasoning.

    Simpkin, Arabella L / Vyas, Jatin M / Armstrong, Katrina A

    Annals of internal medicine

    2018  Volume 168, Issue 10, Page(s) 751–752

    MeSH term(s) Internal Medicine/education ; Thinking
    Language English
    Publishing date 2018-05-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 336-0
    ISSN 1539-3704 ; 0003-4819
    ISSN (online) 1539-3704
    ISSN 0003-4819
    DOI 10.7326/L18-0012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.178/2: Show issues Location:
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  9. Article ; Online: The dendritic cell: the general of the army.

    Vyas, Jatin M

    Virulence

    2012  Volume 3, Issue 7, Page(s) 601–602

    MeSH term(s) Adaptive Immunity ; Animals ; Dendritic Cells/immunology ; Humans ; Immunity, Innate
    Language English
    Publishing date 2012-11-15
    Publishing country United States
    Document type Editorial ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2657572-3
    ISSN 2150-5608 ; 2150-5594
    ISSN (online) 2150-5608
    ISSN 2150-5594
    DOI 10.4161/viru.22975
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The first line of defense: effector pathways of anti-fungal innate immunity

    Ward, Rebecca A / Vyas, Jatin M

    Current opinion in microbiology. 2020 Dec., v. 58

    2020  

    Abstract: The innate immune system is critical to proper host defense against fungal pathogens, which is highlighted by increased susceptibility to invasive disease in immunocompromised patients. Innate cells (e.g. macrophages, neutrophils, dendritic cells, ... ...

    Abstract The innate immune system is critical to proper host defense against fungal pathogens, which is highlighted by increased susceptibility to invasive disease in immunocompromised patients. Innate cells (e.g. macrophages, neutrophils, dendritic cells, eosinophils) are equipped with intricate cell machinery to detect invading fungi and facilitate fungal killing, recruit additional immune cells, and direct the adaptive immune system responses. Understanding the mechanisms that govern a protective response will enable the development of novel treatment strategies. This review focuses on recent insights of signaling and regulation of C-type lectin receptors and their effector mechanisms enabling an effective host antifungal immunity.
    Keywords adaptive immunity ; eosinophils ; fungi ; innate immunity ; lectins ; macrophages ; neutrophils
    Language English
    Dates of publication 2020-12
    Size p. 160-165.
    Publishing place Elsevier Ltd
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1418474-6
    ISSN 1879-0364 ; 1369-5274
    ISSN (online) 1879-0364
    ISSN 1369-5274
    DOI 10.1016/j.mib.2020.10.003
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5514: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
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    Zs.MG 51: Show issues

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