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Article: [Angiodynamic and optical coupling analysis of skin tissue model under finite pressure].

Zhao, Hetong / Zhou, Liang / Liu, Zhaohui / Qiao, Wenlong / Sun, Xiaoxiao / Jiang, Le / Lyu, Yuanyuan

Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi

2024 Volume 39, Issue 3, Page(s) 527–536

Abstract: The pulse amplitude of fingertip volume could be improved by selecting the vascular dense area and applying appropriate pressure above it. In view of this phenomenon, this paper used Comsol Multiphysics 5.6 (Comsol, Sweden), the finite element analysis ... ...

Abstract	The pulse amplitude of fingertip volume could be improved by selecting the vascular dense area and applying appropriate pressure above it. In view of this phenomenon, this paper used Comsol Multiphysics 5.6 (Comsol, Sweden), the finite element analysis software of multi-physical field coupling simulation, to establish the vascular tissue model of a single small artery in fingertips for simulation. Three dimensional Navier-Stokes equations were solved by finite element method, the velocity field and pressure distribution of blood were calculated, and the deformation of blood vessels and surrounding tissues was analyzed. Based on Lambert Beer's Law, the influence of the longitudinal compression displacement of the lateral light surface region and the tissue model on the light intensity signal is investigated. The results show that the light intensity signal amplitude could be increased and its peak value could be reduced by selecting the area with dense blood vessels. Applying deep pressure to the tissue increased the amplitude and peak of the signal. It is expected that the simulation results combined with the previous experimental experience could provide a feasible scheme for improving the quality of finger volume pulse signal.
MeSH term(s)	Computer Simulation ; Fingers ; Finite Element Analysis ; Skin ; Software
Language	Chinese
Publishing date	2024-03-20
Publishing country	China
Document type	Journal Article
ZDB-ID	2576847-5
ISSN	1001-5515
ISSN	1001-5515
DOI	10.7507/1001-5515.202106039
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Article: Trichoderma harzianum

Wei, Yanli / Yang, Han / Hu, Jindong / Li, Hongmei / Zhao, Zhongjuan / Wu, Yuanzheng / Li, Jishun / Zhou, Yi / Yang, Kai / Yang, Hetong

Frontiers in plant science

2023 Volume 14, Page(s) 1258131

Abstract: As one of the major abiotic stresses, salinity can affect crop growth and plant productivity worldwide. The inoculation of rhizosphere or endophytic microorganisms can enhance plant tolerance to salt stresses, but the potential mechanism is not clear. In ...

Abstract	As one of the major abiotic stresses, salinity can affect crop growth and plant productivity worldwide. The inoculation of rhizosphere or endophytic microorganisms can enhance plant tolerance to salt stresses, but the potential mechanism is not clear. In this study,
Language	English
Publishing date	2023-09-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2613694-6
ISSN	1664-462X
ISSN	1664-462X
DOI	10.3389/fpls.2023.1258131
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Article ; Online: Changes in the femoral trochlear induced with estradiol exposure, an experimental study on rats.

Wu, Yu / Zhou, Jin / Li, Yanjun / Yu, Hetong / Li, Weifeng / Guo, Pengfei / Han, Zitao / Guo, Lan / Ma, Zhanbei

Journal of orthopaedic surgery (Hong Kong)

2024 Volume 32, Issue 1, Page(s) 10225536241228344

Abstract: Background: It is well known that estrogen is closely related to bone and joint tissue. Findings indicate that estradiol, injected during pregnancy, passes through the placental barrier and reaches the fetuses in utero where it exerts its action. Since ... ...

Abstract	Background: It is well known that estrogen is closely related to bone and joint tissue. Findings indicate that estradiol, injected during pregnancy, passes through the placental barrier and reaches the fetuses in utero where it exerts its action. Since trochlea appears well established in the prenatal period, however, whether trochlear dysplasia is related to estradiol exposure has not been confirmed, and the pathological process of estradiol exposure-induced trochlear dysplasia remains unclear. This study aimed to establish an estradiol exposure animal model in fetuses and to analyze the morphology of the femoral trochlear in neonatal rats. Methods: 30 pregnant Wistar rats provided by the local Animal Center were assigned randomly into three groups, a high dose estradiol injection group, a low dose estradiol injection group and a blank control group. Gross, cross-sectional observation, histological staining measurement and microcomputed tomography of the rat offspring were conducted to evaluate the morphological changes of the femoral trochlea. Results: The incidence of trochlear dysplasia increased with the concentration of estradiol injection. Gross and cross-sectional observation showed a shallower trochlea groove in two groups with estradiol injection. Histological staining measurement indicated that the trochlear sulcus angle and trochlear sulcus depth were significantly different between the two groups with estradiol injection and the blank control group at 0,5 and 10 days after birth. Subchondral bone loss was observed in the two estradiol injection groups by micro-CT, and the bone loss was found to deteriorate over time. Conclusion: In this study, estradiol exposure in fetuses had an adverse effect on intrauterine development and could induce trochlear dysplasia and bone loss in rat offspring. In addition, this study also showed that the higher concentration of estradiol injection in pregnant rats, the more incidence of trochlear dysplasia in rat offspring.
MeSH term(s)	Female ; Pregnancy ; Rats ; Animals ; Estradiol ; Rats, Wistar ; Cross-Sectional Studies ; X-Ray Microtomography ; Placenta
Chemical Substances	Estradiol (4TI98Z838E)
Language	English
Publishing date	2024-03-15
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1493368-8
ISSN	2309-4990 ; 1022-5536
ISSN (online)	2309-4990
ISSN	1022-5536
DOI	10.1177/10225536241228344
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Zs.A 5104: Show issues

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Article ; Online: Rationally Designed Matrix-Free Carbon Dots with Wavelength-Tunable Room-Temperature Phosphorescence.

Qi, Hetong / Cui, Xiaofeng / Zhang, Hengqi / Tong, Yuxi / Qian, Manping / Zhou, Wenshuai / Ding, Shujiang / Qi, Honglan

Chemistry, an Asian journal

2023 Volume 18, Issue 6, Page(s) e202201284

Abstract: We report the rational design of the matrix-free carbon dots (C-dots) with long wavelength and wavelength-tunable room-temperature phosphorescence (RTP). Taking advantage of microwave-assisted heating treatment, three RTP C-dots in boric acid (BA) ... ...

Abstract	We report the rational design of the matrix-free carbon dots (C-dots) with long wavelength and wavelength-tunable room-temperature phosphorescence (RTP). Taking advantage of microwave-assisted heating treatment, three RTP C-dots in boric acid (BA) composites are synthesized by using diethylenetriaminepentakis (methylphosphonic acid) as a multiple-sites crosslink agent, a moderately acid catalyst and P source; phenylenediamines (either o-PD, m-PD, or p-PD, respectively) as building block while BA as a carbonization-retardant matrix. After the water-soluble BA matrix is removed by dialysis, three matrix-free C-dots are obtained with RTP emission at 540, 550 and 570 nm under an excitation wavelength of 365 nm. Alterations of RTP emission of three matrix-free C-dots are ascribed to the difference in their particle size and band gap from n-π* transition. Furthermore, the application of three matrix-free C-dots are successfully performed in information encryption and decryption.
Language	English
Publishing date	2023-02-13
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2233006-9
ISSN	1861-471X ; 1861-4728
ISSN (online)	1861-471X
ISSN	1861-4728
DOI	10.1002/asia.202201284
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Article: Green credit policy, government behavior and green innovation quality of enterprises

Wang, Hetong / Qi, Shaozhou / Zhou, Chaobo / Zhou, Jingjie / Huang, Xiaoyan

Journal of cleaner production. 2022 Jan. 10, v. 331

2022

Abstract: This study takes Green Credit Guidelines in China as a quasi-natural experiment to examine its effect on the quality of green innovation in heavily polluting enterprises. Based on the data of Chinese listed companies from 2008 to 2019, DID model, and a ... ...

Abstract	This study takes Green Credit Guidelines in China as a quasi-natural experiment to examine its effect on the quality of green innovation in heavily polluting enterprises. Based on the data of Chinese listed companies from 2008 to 2019, DID model, and a series of robustness tests, findings show that Green Credit Guidelines significantly improve the quality of enterprises' green innovation. The positive effect is more significant in state-owned enterprises and those in the eastern region and less financially developed areas. The officials' promotion pressure and fiscal decentralization have negative and positive moderating effects, respectively. Additional analysis demonstrates that the quality improvement of enterprises’ green innovation can further increase their economic returns. Specifically, the competitiveness and market value of enterprise products are enhanced. The results provide enterprises with theoretical guidance on how to deal with environmental regulation. The results also provide countries around the world, especially developing countries, with important reference to implement green credit policy to achieve sustainable development.
Keywords	business enterprises ; credit ; decentralization ; environmental law ; issues and policy ; market value ; public ownership ; sustainable development ; sustainable technology ; China
Language	English
Dates of publication	2022-0110
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0959-6526
DOI	10.1016/j.jclepro.2021.129834
Database	NAL-Catalogue (AGRICOLA)

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Article: Comprehensive Study of Tumor Immune Microenvironment and Relevant Genes in Hepatocellular Carcinoma Identifies Potential Prognostic Significance.

Chen, Wenbiao / Zhang, Xujun / Bi, Kefan / Zhou, Hetong / Xu, Jia / Dai, Yong / Diao, Hongyan

Frontiers in oncology

2020 Volume 10, Page(s) 554165

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2020-09-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2020.554165
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Article ; Online: Clinical characteristics and prognosis of patients with hypertrophic cardiomyopathy and heart failure with preserved ejection fraction.

Chen, Qin-Fen / Hu, Jiandong / Hu, Jie / Nijjar, Prabhjot S / Xu, Jiahui / Shi, Shanzhen / Liang, Dongjie / Liao, Hetong / Gao, Jiaqi / Lin, Wei-Hong / You, Shenban / Zhou, Xiao-Dong

Clinical research in cardiology : official journal of the German Cardiac Society

2024 Volume 113, Issue 5, Page(s) 761–769

Abstract: Background: Whether heart failure with preserved ejection fraction (HFpEF) is associated with an increased risk of developing systolic dysfunction and a poor prognosis in hypertrophic cardiomyopathy (HCM) patients is unknown.: Objective: We aimed to ... ...

Abstract	Background: Whether heart failure with preserved ejection fraction (HFpEF) is associated with an increased risk of developing systolic dysfunction and a poor prognosis in hypertrophic cardiomyopathy (HCM) patients is unknown. Objective: We aimed to assess risk factors for the development of end-stage (ES) heart failure (HF) (ejection fraction < 50%) and compare the prognosis of different HF phenotypes. Methods: This retrospective study was conducted on patients with HCM in China between January 2009 and February 2023. Patients were stratified into three different groups: HCM-non-HF, HCM-HFpEF and HCM-heart failure with reduced ejection fraction (HCM-HFrEF). The primary outcome was a composite of major adverse cardiac events (MACEs), including all-cause deaths, HF hospitalization, sudden cardiac death and ventricular tachycardia. Results: Of 3,620 HCM patients enrolled, 1,553 (42.9%) had non-HF, 1,666 (46.0%) had HFpEF, and 579 patients (11.1%) had HFrEF at baseline. During the median follow-up period of 4.0 years (IQR 1.4-9.4 years), patients with HCM-HFpEF exhibited a higher incidence of ES-HF than those with HCM-non-HF (12.4% vs. 2.7%, P < 0.001). HFpEF was an independent risk factor for ES-HF development (HR 3.84, 2.54-5.80, P < 0.001). MACEs occurred in 26.9% with a higher incidence in HCM-HFpEF than HCM-non-HF (36.6% vs 12.2%, P < 0.001). HFpEF was an independent predictor of MACEs (HR 2.13, 1.75-2.59, P < 0.001). Conclusions: HFpEF is common in HCM. Compared to non-HF, it increases the risk of LVEF decline and poor prognosis. It may aid in risk stratification and need close echocardiography follow-up.
MeSH term(s)	Humans ; Heart Failure ; Stroke Volume ; Retrospective Studies ; Prognosis ; Cardiomyopathy, Hypertrophic/complications ; Ventricular Function, Left
Language	English
Publishing date	2024-01-10
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2213295-8
ISSN	1861-0692 ; 1861-0684
ISSN (online)	1861-0692
ISSN	1861-0684
DOI	10.1007/s00392-023-02371-5
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Article ; Online: IL-17A produced by invariant natural killer T cells and CD3

Jia, Hongyu / Chen, Jianing / Zhang, Xujun / Bi, Kefan / Zhou, Hetong / Liu, Tianxing / Xu, Jia / Diao, Hongyan

Journal of leukocyte biology

2022 Volume 112, Issue 5, Page(s) 1079–1087

Abstract: Primary biliary cholangitis (PBC) is characterized as interlobular bile duct injury and fibrosis, which results from the loss of tolerance to self-antigens. However, the exact pathologic mechanism leading to injury and fibrosis in PBC patients is not ... ...

Abstract	Primary biliary cholangitis (PBC) is characterized as interlobular bile duct injury and fibrosis, which results from the loss of tolerance to self-antigens. However, the exact pathologic mechanism leading to injury and fibrosis in PBC patients is not fully understood. Therefore, in this study, we examined the role of the T cell subsets in PBC patients and healthy controls (HCs). A higher number of invariant Natual killer T (iNKT) cells as well as CD3
MeSH term(s)	Humans ; Liver Cirrhosis, Biliary ; Natural Killer T-Cells ; Interleukin-17 ; Liver Cirrhosis ; Fibrosis ; Autoantigens ; Autoantibodies ; Antigens, CD1d
Chemical Substances	Interleukin-17 ; Autoantigens ; Autoantibodies ; CD1D protein, human ; Antigens, CD1d
Language	English
Publishing date	2022-06-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	605722-6
ISSN	1938-3673 ; 0741-5400
ISSN (online)	1938-3673
ISSN	0741-5400
DOI	10.1002/JLB.2A0622-586RRRR
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Article ; Online: Seroprevalence and risk factor analysis of Toxoplasma gondii infection in Siberian tigers (Panthera tigris altaica) and giant pandas (Ailuropoda melanoleuca) in China.

Liu, Hetong / Deng, Linhua / Xu, Haitao / Lu, Yaxian / Tian, Lihong / Chai, Hongliang / Liu, Quan / Wang, Yajun / Zhou, Xiaoyu / Hou, Zhijun

Parasitology research

2022 Volume 122, Issue 2, Page(s) 493–496

Abstract: Toxoplasmosis, caused by Toxoplasma gondii, is a worldwide zoonosis. The aim of the present study was to detect the seroprevalence of T. gondii infection and associated risk factors among Siberian tigers (Panthera tigris altaica) and giant pandas ( ... ...

Abstract	Toxoplasmosis, caused by Toxoplasma gondii, is a worldwide zoonosis. The aim of the present study was to detect the seroprevalence of T. gondii infection and associated risk factors among Siberian tigers (Panthera tigris altaica) and giant pandas (Ailuropoda melanoleuca) in China. Blood samples from 112 Siberian tigers and 22 giant pandas were tested for immunoglobulin G (IgG) against T. gondii by enzyme-linked immunosorbent assay (ELISA). The seroprevalence of T. gondii infection was 7.14% among Siberian tigers and 9.09% among giant pandas. No risk factors were found to be significantly associated with seroprevalence (P > 0.05). This is the first study to evaluate T. gondii infection in Siberian tigers on a large scale in China, and it also updates the information regarding the positivity rate of T. gondii infection among giant pandas in China.
MeSH term(s)	Animals ; Humans ; Ursidae ; Tigers ; Seroepidemiologic Studies ; Toxoplasmosis ; Toxoplasma ; China/epidemiology ; Antibodies, Protozoan
Chemical Substances	Antibodies, Protozoan
Language	English
Publishing date	2022-12-06
Publishing country	Germany
Document type	Journal Article
ZDB-ID	284966-5
ISSN	1432-1955 ; 0932-0113 ; 0044-3255
ISSN (online)	1432-1955
ISSN	0932-0113 ; 0044-3255
DOI	10.1007/s00436-022-07747-6
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Article ; Online: Soil salinity determines the assembly of endophytic bacterial communities in the roots but not leaves of halophytes in a river delta ecosystem

Zhou, Yi / Wei, Yanli / Ryder, Maarten / Li, Hongmei / Zhao, Zhongjuan / Toh, Ruey / Yang, Peizhi / Li, Jishun / Yang, Hetong / Denton, Matthew D

Geoderma. 2023 May, v. 433 p.116447-

2023

Abstract: Although soil and rhizosphere microbiomes in highly saline environments have been well-studied, the role of soil salinity in the ecological processes affecting endophyte colonization and persistence remain largely unclear in halophytic plants. The ... ...

Abstract	Although soil and rhizosphere microbiomes in highly saline environments have been well-studied, the role of soil salinity in the ecological processes affecting endophyte colonization and persistence remain largely unclear in halophytic plants. The present study sampled young and mature plants of the halophyte Suaeda salsa from 42 sites in the Yellow River Delta, China that varied in soil salinity. Soil physicochemical properties, root and leaf microbiomes, phylogenetic variation among plant ecotypes, and leaf metabolites were analysed. In the roots of both young and mature plants, soil salinity significantly influenced the composition of the endophytic microbiota (r = 0.29 ∼ 0.45, P < 0.001), and negatively correlated with endophyte alpha-diversity (r = -0.75 ∼ -0.78, P < 0.001). Leaf microbiome dissimilarity increased with geographic distance (r = 0.17 ∼ 0.26, P < 0.001), based on a distance-decay model, and was associated with plant phylogenetic variation (r = 0.15, P = 0.015 for young plants only). Additionally, leaf microbiome diversity and composition were correlated with soil age, pH, P content, and certain leaf metabolite compounds, but not with soil salinity. The dominant genera observed in young roots were Mesorhizobium spp. and Rhodomicrobium spp., while Pelagibius spp. was dominant in mature roots, and Pseudomonas spp. and Kushneria spp. were dominant in leaves. Soil salinity exerted a strong deterministic effect on the diversity and composition of the root endophyte community, while the acquisition and assembly of the leaf microbiome was affected by the dispersal effects, and the leaf metabolism of the host halophyte.
Keywords	Mesorhizobium ; Pseudomonas ; Rhodomicrobium ; Suaeda salsa ; age of soil ; ecosystems ; ecotypes ; endophytes ; halophytes ; leaves ; metabolism ; metabolites ; microbiome ; microorganisms ; models ; pH ; phylogeny ; rhizosphere ; river deltas ; soil salinity ; species diversity ; China ; Yellow River ; YRD ; ASV ; KEGG ; MSTFA ; ML ; NMDS ; PERMANOVA ; AIC ; STAMP ; MaAsLin2 ; Bacteria ; Endosphere ; Phyllosphere ; Beneficial microbe ; Plant-growth promoting bacteria
Language	English
Dates of publication	2023-05
Publishing place	Elsevier B.V.
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	281080-3
ISSN	1872-6259 ; 0016-7061
ISSN (online)	1872-6259
ISSN	0016-7061
DOI	10.1016/j.geoderma.2023.116447
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