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  1. Book ; Online: Climate change, human health, and sustainable development / W. J. M. Martens, R. Slooff, & E. K. Jackson ; Changements climatiques, santé et développement durable

    Martens, W. J. M / Slooff, Rudolf / Jackson, E. K

    1997  

    Abstract: In English with summary in French ... Published in Spanish in Revista Panamericana de Salud Pública Pan American Journal of Public Health 1998 ... 4(2) : 100- ... ...

    Abstract In English with summary in French

    Published in Spanish in Revista Panamericana de Salud Pública Pan American Journal of Public Health 1998

    4(2) : 100-105
    Keywords Climate ; Environmental policy ; Ecosystem ; Sustainability ; Models ; Statistical ; Development indicators ; Environment and Public Health
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Book ; Article ; Online: Climate change, human health, and sustainable development / W. J. M. Martens, R. Slooff, & E. K. Jackson ; Changements climatiques, santé et développement durable

    Martens, W. J. M / Slooff, Rudolf / Jackson, E. K

    1997  

    Abstract: In English with summary in French ... Published in Spanish in Revista Panamericana de Salud Pública Pan American Journal of Public Health 1998 ... 4(2) : 100- ... ...

    Abstract In English with summary in French

    Published in Spanish in Revista Panamericana de Salud Pública Pan American Journal of Public Health 1998

    4(2) : 100-105
    Keywords Climate ; Environmental Policy ; Ecosystem ; Models ; Statistical ; Sustainable Development ; Environment and Public Health
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Towards Detection of a Long-lived Protonated Metal Cation: Generation of GeH(2+) Using High-Energy Collisions This research was supported by the Deutsche Forschungsgemeinschaft, the Volkswagen-Stiftung, and the Fonds der Chemischen Industrie. The Konrad-Zuse-Zentrum, Berlin, is acknowledged for generous allocation of computer time. R.S. is grateful to the Deutscher Akademischer Austauschdienst (DAAD) for financial support, and thanks Dr. K. V. Raghavan, Director of the Indian Institute of Chemical Technology, for his encouragement and assistance.

    Jackson / Diefenbach / Srinivas / Schröder / Schwarz

    Angewandte Chemie (International ed. in English)

    2000  Volume 39, Issue 8, Page(s) 1445–1447

    Language English
    Publishing date 2000-04
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/(sici)1521-3773(20000417)39:8<1445::aid-anie1445>3.0.co;2-y
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  4. Article ; Online: Trends in revenue on undergraduate and graduate medical education recruitment, 2004-2021.

    Das, Rishub K / Makhoul, Alan T / Jackson, Kianna R / Drolet, Brian C

    American journal of surgery

    2024  

    Language English
    Publishing date 2024-04-17
    Publishing country United States
    Document type Editorial
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/j.amjsurg.2024.04.019
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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: Rapid isolation and quantification of extracellular vesicles from suspension-adapted human embryonic kidney cells using capillary-channeled polymer fiber spin-down tips.

    Jackson, Kaylan K / Marcus, R Kenneth

    Electrophoresis

    2022  Volume 44, Issue 1-2, Page(s) 190–202

    Abstract: Exosomes, a subset of extracellular vesicles (EVs, 30-200-nm diameter), serve as biomolecular snapshots of their cell of origin and vehicles for intercellular communication, playing roles in biological processes, including homeostasis maintenance and ... ...

    Abstract Exosomes, a subset of extracellular vesicles (EVs, 30-200-nm diameter), serve as biomolecular snapshots of their cell of origin and vehicles for intercellular communication, playing roles in biological processes, including homeostasis maintenance and immune modulation. The large-scale processing of exosomes for use as therapeutic vectors has been proposed, but these applications are limited by impure, low-yield recoveries from cell culture milieu (CCM). Current isolation methods are also limited by tedious and laborious workflows, especially toward an isolation of EVs from CCM for therapeutic applications. Employed is a rapid (<10 min) EV isolation method on a capillary-channeled polymer fiber spin-down tip format. EVs are isolated from the CCM of suspension-adapted human embryonic kidney cells (HEK293), one of the candidate cell lines for commercial EV production. This batch solid-phase extraction technique allows 10
    MeSH term(s) Humans ; Polymers ; HEK293 Cells ; Extracellular Vesicles/metabolism ; Exosomes ; Kidney
    Chemical Substances Polymers
    Language English
    Publishing date 2022-09-04
    Publishing country Germany
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 619001-7
    ISSN 1522-2683 ; 0173-0835
    ISSN (online) 1522-2683
    ISSN 0173-0835
    DOI 10.1002/elps.202200149
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1868: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Habitat and respiratory strategy effects on hypoxia performance in anuran tadpoles.

    Phillips, Jackson R / Nicolau, Gary K / Ngwenya, Shane S / Jackson, Emily A / Womack, Molly C

    Integrative and comparative biology

    2024  

    Abstract: A critical component of animal conservation in a changing world is an understanding of the physiological resilience of animals to different conditions. In many aquatic animals, hypoxia (low environmental oxygen levels) is a regular occurrence, but the ... ...

    Abstract A critical component of animal conservation in a changing world is an understanding of the physiological resilience of animals to different conditions. In many aquatic animals, hypoxia (low environmental oxygen levels) is a regular occurrence, but the likelihood and severity of hypoxia varies across habitats. Fast-flowing, stream-like habitats are never hypoxic, so long as flow is maintained. Do animals from such habitats retain the capacity to survive hypoxic conditions? We use aquatic frog tadpoles to test the effects of natural habitat on performance in hypoxia in an experimental framework, finding that stream-living tadpoles have reduced performance in hypoxia. Tadpoles also vary in lung presence, with some species able to breathe air during hypoxia. We found that among lunged tadpoles, air-breathing rates increase in hypoxia in pond-living species but not stream-living species. Lung presence was also found to influence hypoxia performance, as lungless, stream-living tadpoles were found to be especially vulnerable to hypoxia, while pond-living, lungless tadpoles appeared largely resilient to hypoxia. We consider the ramifications of our findings on conservation outlooks and strategies for frogs and their tadpoles, suggesting that stream-living tadpoles, and especially lungless, stream-living tadpoles, may be particularly at risk to factors that reduce stream flow. Thus, a primary goal for conservation and management of species with stream-living tadpoles should be the maintenance of year-round streamflow, which oxygenates waters and prevents hypoxia.
    Language English
    Publishing date 2024-04-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2159110-6
    ISSN 1557-7023 ; 1540-7063
    ISSN (online) 1557-7023
    ISSN 1540-7063
    DOI 10.1093/icb/icae017
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  7. Article: Sir Percy W. G. Sargent, K.B., C.M.G., M.A., M.B., M. Ch. (Cantab.), F.R.C.S.

    Jackson, H

    Surgical neurology

    1976  Volume 6, Issue 4, Page(s) 209–210

    MeSH term(s) History, 20th Century ; Neurosurgery/history ; United Kingdom
    Language English
    Publishing date 1976-10
    Publishing country United States
    Document type Biography ; Historical Article ; Journal Article
    ZDB-ID 221938-4
    ISSN 1879-3339 ; 0090-3019
    ISSN (online) 1879-3339
    ISSN 0090-3019
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1159: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article: A rapid capillary-channeled polymer (C-CP) fiber spin-down tip approach for the isolation of plant-derived extracellular vesicles (PDEVs) from 20 common fruit and vegetable sources

    Jackson, Kaylan K. / Mata, Carolina / Marcus, R. Kenneth

    Talanta. 2023 Jan. 15, v. 252

    2023  

    Abstract: In the emerging field of phyto-nanotechnology, 30–200 nm plant-derived extracellular vesicles (PDEVs) are now known to contain active biomolecules that mediate cell-to-cell communication processes in a manner very similar to exosomes in mammalian cells. ... ...

    Abstract In the emerging field of phyto-nanotechnology, 30–200 nm plant-derived extracellular vesicles (PDEVs) are now known to contain active biomolecules that mediate cell-to-cell communication processes in a manner very similar to exosomes in mammalian cells. The ability to deliver cargo across cellular membranes suggests that botanical systems could be used in the mass production of therapeutic vectors to transport exogenous molecules into human cells. The fundamental biochemical characteristics of PDEVs remain poorly understood due to the lack of efficient methods to isolate and characterize these nanovesicles. Described here is a rapid PDEV isolation method using a hydrophobic interaction chromatography (HIC)-based extraction performed on a capillary-channeled polymer (C-CP) fiber spin-down tip. The C-CP solid-phase extraction method is performed using a standard table-top centrifuge, enabling the isolation and concentration of PDEVs (>1 × 10¹⁰ particles from 100 μL of sample). PDEVs of 189 nm average diameter were obtained from 20 common fruit and vegetable stocks. The size, integrity, and purity of the recovered PDEVs were assessed using transmission electron microscopy (TEM), multi-angle light scattering (MALS), absorbance quantification, a protein purity assay, and an enzyme-linked immunosorbent assay (ELISA) to the PEN1 PDEV surface marker protein. The HIC C-CP tip isolation method allows for concentrated PDEV recoveries (up to 2 × 10¹¹ EVs) on reasonable time scales (<15 min) and low cost (<$1), with the purity and integrity fit for fundamental research and downstream applications.
    Keywords absorbance ; biochemical compounds ; cell communication ; enzyme-linked immunosorbent assay ; exosomes ; fruits ; humans ; hydrophobic interaction chromatography ; isolation techniques ; polymers ; solid phase extraction ; therapeutics ; transmission electron microscopy ; vegetables
    Language English
    Dates of publication 2023-0115
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2022.123779
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  9. Article ; Online: Rapid isolation and quantification of extracellular vesicles from suspension‐adapted human embryonic kidney cells using capillary‐channeled polymer fiber spin‐down tips

    Jackson, Kaylan K. / Marcus, R. Kenneth

    ELECTROPHORESIS. 2023 Jan., v. 44, no. 1-2 p.190-202

    2023  

    Abstract: Exosomes, a subset of extracellular vesicles (EVs, 30–200‐nm diameter), serve as biomolecular snapshots of their cell of origin and vehicles for intercellular communication, playing roles in biological processes, including homeostasis maintenance and ... ...

    Abstract Exosomes, a subset of extracellular vesicles (EVs, 30–200‐nm diameter), serve as biomolecular snapshots of their cell of origin and vehicles for intercellular communication, playing roles in biological processes, including homeostasis maintenance and immune modulation. The large‐scale processing of exosomes for use as therapeutic vectors has been proposed, but these applications are limited by impure, low‐yield recoveries from cell culture milieu (CCM). Current isolation methods are also limited by tedious and laborious workflows, especially toward an isolation of EVs from CCM for therapeutic applications. Employed is a rapid (<10 min) EV isolation method on a capillary‐channeled polymer fiber spin‐down tip format. EVs are isolated from the CCM of suspension‐adapted human embryonic kidney cells (HEK293), one of the candidate cell lines for commercial EV production. This batch solid‐phase extraction technique allows 10¹² EVs to be obtained from only 100‐µl aliquots of milieu, processed using a benchtop centrifuge. The tip‐isolated EVs were characterized using transmission electron microscopy, multi‐angle light scattering, absorbance quantification, an enzyme‐linked immunosorbent assay to tetraspanin marker proteins, and a protein purity assay. It is believed that the demonstrated approach has immediate relevance in research and analytical laboratories, with opportunities for production‐level scale‐up projected.
    Keywords absorbance ; cell communication ; cell culture ; electrophoresis ; enzyme-linked immunosorbent assay ; exosomes ; homeostasis ; humans ; immunomodulation ; isolation techniques ; kidneys ; polymers ; solid phase extraction ; therapeutics ; transmission electron microscopy
    Language English
    Dates of publication 2023-01
    Size p. 190-202.
    Publishing place John Wiley & Sons, Ltd
    Document type Article ; Online
    Note JOURNAL ARTICLE
    ZDB-ID 619001-7
    ISSN 1522-2683 ; 0173-0835
    ISSN (online) 1522-2683
    ISSN 0173-0835
    DOI 10.1002/elps.202200149
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    In stock of ZB MED Bonn / Germany

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  10. Article ; Online: What are the evidence bases for developing models of rehabilitation for older people with mental illness in Australia?

    McKay, Roderick / Jackson, Kate

    Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists

    2023  Volume 31, Issue 5, Page(s) 601–606

    Abstract: Objective: This paper updates clinicians and service leaders on evidence bases relevant to rehabilitation for older Australians with mental illness.: Methods: Narrative review of literature and relevant public domain data supported by reflections on ... ...

    Abstract Objective: This paper updates clinicians and service leaders on evidence bases relevant to rehabilitation for older Australians with mental illness.
    Methods: Narrative review of literature and relevant public domain data supported by reflections on NSW service development.
    Results: There is a paucity of high-quality evidence regarding mental health rehabilitation in older people. Available evidence supports integrating lessons from physical healthcare with adaptations of 'adult' mental health rehabilitation. Adaptation is required to respond to the specific needs, strengths and service use of older people with mental illness. Challenges for older people include ageism, increased physical and cognitive comorbidities, lower access to mental health services and earlier residential aged care entry. Strengths of older people include an ongoing desire for recovery, ongoing developmental change and often closer connections with carers and GPs. Evidence is consistent with evaluation of relevant NSW service models and initiatives including the Pathways to Community Living Initiative. Integration of recovery-oriented practice and wellness models may provide a framework for future innovative inpatient and community-based models.
    Conclusions: There is sufficient evidence to guide development of models of rehabilitation with older people, but innovation and evaluation are essential if older people are to have equal opportunities in their recovery journeys.
    MeSH term(s) Humans ; Aged ; Australia ; Mental Disorders/psychology ; Mental Health Services ; Psychiatric Rehabilitation ; Health Services Accessibility
    Language English
    Publishing date 2023-08-24
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 2213198-X
    ISSN 1440-1665 ; 1039-8562
    ISSN (online) 1440-1665
    ISSN 1039-8562
    DOI 10.1177/10398562231190831
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    Zs.MO 581: Show issues

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