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  1. Article ; Online: The 11th Annual Joseph M. Still Burn Symposium.

    Hills, Jocelyn / Culnan, Derek M / Lineaweaver, William C / Mullins, Fred

    Annals of plastic surgery

    2019  Volume 82, Issue 3 Suppl 2, Page(s) S145

    MeSH term(s) Burn Units/history ; Burn Units/organization & administration ; Burns/diagnosis ; Burns/therapy ; Congresses as Topic/history ; History, 21st Century ; Humans ; United States
    Language English
    Publishing date 2019-02-06
    Publishing country United States
    Document type Biography ; Historical Article ; Introductory Journal Article
    ZDB-ID 423835-7
    ISSN 1536-3708 ; 0148-7043
    ISSN (online) 1536-3708
    ISSN 0148-7043
    DOI 10.1097/SAP.0000000000001824
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1419: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  2. Article ; Online: Sensitive quantification of m.3243A>G mutational proportion in non-retinal tissues and its relationship with visual symptoms.

    Mullin, Nathaniel K / Anfinson, Kristin R / Riker, Megan J / Wieland, Kelsey L / Tatro, Nicole J / Scheetz, Todd E / Mullins, Robert F / Stone, Edwin M / Tucker, Budd A

    Human molecular genetics

    2021  Volume 31, Issue 5, Page(s) 775–782

    Abstract: The m.3243A>G mutation in the mitochondrial genome commonly causes retinal degeneration in patients ... episodes. Like other mitochondrial mutations, m.3243A>G is inherited from the mother with a variable ... proportion of wild type and mutant mitochondrial genomes in different cells. The mechanism by which the m ...

    Abstract The m.3243A>G mutation in the mitochondrial genome commonly causes retinal degeneration in patients with maternally inherited diabetes and deafness and mitochondrial encephalopathy, lactic acidosis and stroke-like episodes. Like other mitochondrial mutations, m.3243A>G is inherited from the mother with a variable proportion of wild type and mutant mitochondrial genomes in different cells. The mechanism by which the m.3243A>G variant in each tissue relates to the manifestation of disease phenotype is not fully understood. Using a digital PCR assay, we found that the % m.3243G in skin derived dermal fibroblasts was positively correlated with that of blood from the same individual. The % m.3243G detected in fibroblast cultures remained constant over multiple passages and was negatively correlated with mtDNA copy number. Although the % m.3243G present in blood was not correlated with severity of vision loss, as quantified by Goldmann visual field, a significant negative correlation between % m.3243G and the age of onset of visual symptoms was detected. Altogether, these results indicate that precise measurement of % m.3243G in clinically accessible tissues such as skin and blood may yield information relevant to the management of retinal m.3243A>G-associated disease.
    MeSH term(s) DNA, Mitochondrial/genetics ; Deafness ; Diabetes Mellitus, Type 2/genetics ; Humans ; MELAS Syndrome/genetics ; Mitochondrial Diseases/genetics ; Mutation
    Chemical Substances DNA, Mitochondrial
    Language English
    Publishing date 2021-09-29
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1108742-0
    ISSN 1460-2083 ; 0964-6906
    ISSN (online) 1460-2083
    ISSN 0964-6906
    DOI 10.1093/hmg/ddab289
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3469: Show issues Location:
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  3. Article ; Online: Reply to M. Schlumbrecht et al.

    Mullins, Megan A / Cote, Michele L

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2019  Volume 37, Issue 35, Page(s) 3465–3466

    MeSH term(s) Continental Population Groups ; Female ; Humans ; Hysterectomy ; Incidence ; Neoplasms
    Language English
    Publishing date 2019-10-02
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.19.01883
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 650: Show issues

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  4. Article ; Online: The 12th Annual Joseph M. Still Burn Symposium.

    Lineaweaver, William C / Hills, Jocelyn / Mullins, Fred

    Annals of plastic surgery

    2020  Volume 84, Issue 3S Suppl 2, Page(s) S133

    MeSH term(s) Burn Units/history ; Burn Units/organization & administration ; Burns/therapy ; Congresses as Topic/history ; History, 21st Century ; Humans ; United States
    Language English
    Publishing date 2020-02-05
    Publishing country United States
    Document type Historical Article ; Journal Article
    ZDB-ID 423835-7
    ISSN 1536-3708 ; 0148-7043
    ISSN (online) 1536-3708
    ISSN 0148-7043
    DOI 10.1097/SAP.0000000000002306
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1419: Show issues Location:
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  5. Article ; Online: Label-free quantitative proteomic analysis of M. longissimus dorsi from cattle during dietary restriction and subsequent compensatory growth.

    Mullins, Yvonne / Keogh, Kate / Kenny, David A / Kelly, Alan / O' Boyle, Padraig / Waters, Sinéad M

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 2613

    Abstract: ... access to feed for successive 55 days (Period 2). M. longissimus dorsi samples were collected ...

    Abstract Compensatory growth (CG) is a naturally occurring physiological process whereby an animal has the ability to undergo enhanced growth following a period of restricted feeding. This studies objective was to identify key proteins involved in the expression of CG. Forty Holstein Friesian bulls were equally assigned to one of four groups. R1 and R2 groups were subjected to restricted feed allowance for 125 days (Period 1). A1 and A2 animals had ad libitum access to feed in Period 1. Following Period 1, all animals from R1 and A1 were slaughtered. Remaining animals (R2 and A2) were slaughtered following ad libitum access to feed for successive 55 days (Period 2). M. longissimus dorsi samples were collected at slaughter from all animals. Proteins were isolated from samples and subjected to label-free mass spectrometry proteomic quantification. Proteins which were differentially abundant during CG (n = 39) were involved in cellular binding processes, oxidative phosphorylation and mitochondrial function. There was also evidence for up regulation of three pathways involved in nucleotide biosynthesis. Genetic variants in or regulating genes pertaining to proteins identified in this study may hold potential for use as DNA based biomarkers for genomic selection of animals with a greater ability to undergo CG.
    MeSH term(s) Animal Feed/analysis ; Animal Nutritional Physiological Phenomena ; Animals ; Cattle/genetics ; Cattle/growth & development ; Cattle/physiology ; Diet/veterinary ; Food Deprivation ; Male ; Muscle, Skeletal/growth & development ; Muscle, Skeletal/physiology ; Proteins/analysis ; Proteins/genetics ; Proteins/metabolism ; Transcriptome
    Chemical Substances Proteins
    Language English
    Publishing date 2020-02-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-59412-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Joseph M. Still Burn Symposium.

    Lineaweaver, William C / Hills, Jocelyn / Mullins, Fred

    Annals of plastic surgery

    2018  Volume 80, Issue 3 Suppl 2, Page(s) S87

    Language English
    Publishing date 2018-01-06
    Publishing country United States
    Document type Editorial
    ZDB-ID 423835-7
    ISSN 1536-3708 ; 0148-7043
    ISSN (online) 1536-3708
    ISSN 0148-7043
    DOI 10.1097/SAP.0000000000001269
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1419: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Human Colorectal Carcinoma Infiltrating B Lymphocytes Are Active Secretors of the Immunoglobulin Isotypes A, G, and M.

    Mullins, Christina Susanne / Gock, Michael / Krohn, Mathias / Linnebacher, Michael

    Cancers

    2019  Volume 11, Issue 6

    Abstract: Despite the importance of tumor infiltrating B cells (TiBc) in immunological circuits, their functional role is scarcely investigated. Here, we analyzed immunoglobulin (Ig) secretion of the subtypes IgA, IgG, and IgM of TiBc from freshly resected primary ...

    Abstract Despite the importance of tumor infiltrating B cells (TiBc) in immunological circuits, their functional role is scarcely investigated. Here, we analyzed immunoglobulin (Ig) secretion of the subtypes IgA, IgG, and IgM of TiBc from freshly resected primary and secondary colorectal carcinomas (CRC) by FluoroSpot (
    Language English
    Publishing date 2019-06-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers11060776
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: HIV-1 group M conserved elements vaccine.

    Rolland, Morgane / Nickle, David C / Mullins, James I

    PLoS pathogens

    2007  Volume 3, Issue 11, Page(s) e157

    MeSH term(s) AIDS Vaccines/genetics ; Amino Acid Sequence ; Animals ; Base Sequence ; Conserved Sequence ; HIV-1/genetics ; Humans ; Immunotherapy, Active/methods ; Mutation ; Viral Proteins/genetics
    Chemical Substances AIDS Vaccines ; Viral Proteins
    Language English
    Publishing date 2007-12-06
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2205412-1
    ISSN 1553-7374 ; 1553-7366
    ISSN (online) 1553-7374
    ISSN 1553-7366
    DOI 10.1371/journal.ppat.0030157
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Soft X-ray spectroscopic studies of the electronic structure of M:BiVO4 (M = Mo, W) single crystals

    Jovic, V / Bluhm, H / Jovic, B / Lamoureux, B / Laverock, J / Mullins, C. B / Rettie, A. J. E / Singh, V. R / Smith, K. E / Söhnel, T / Su, T.-Y / Wilson, D / Zhou, J.-S

    Journal of materials chemistry A. 2015 Nov. 24, v. 3, no. 47

    2015  

    Abstract: ... structure of 0.3–0.6 at% M:BiVO4 (M = Mo or W). The results are interpreted in the context of current ... measured in valence band resonant photoelectron spectroscopy of M:BiVO4, point to the population of inter ... of an applied bias in M:BiVO4, linked to small-polaron formation. We tentatively assign it as a deep trap state ...

    Abstract Bismuth vanadate, BiVO4, is a promising material for use as an anode in photoelectrochemical water splitting. However, its conversion efficiency is limited by poor bulk charge transport, which is via small-polarons. We report here the use of a suite of X-ray spectroscopic probes to determine the electronic structure of 0.3–0.6 at% M:BiVO4 (M = Mo or W). The results are interpreted in the context of current theories regarding the influence of doping on the existence of inter-band gap small-polaron states and their effect on the conversion efficiency of BiVO4. Preliminary X-ray absorption and emission measurements reveal that doping widens the band gap from 2.50 to 2.75 eV, whereas the indirect nature of the band gap remains unaffected. X-ray absorption spectroscopy verified that the doping levels did not affect the distorted tetrahedral environment of V5+ in BiVO4. For BiVO4 and W:BiVO4, V L3 resonant inelastic X-ray scattering showed energy loss features related to charge transfer from low lying valence metal/oxygen states to unoccupied V eg conduction band states. A 3.8 eV energy loss feature, coupled with small polaron-like peaks measured in valence band resonant photoelectron spectroscopy of M:BiVO4, point to the population of inter-band gap V 3d states of eg symmetry. The data reveals the existence of a band gap state in the absence of an applied bias in M:BiVO4, linked to small-polaron formation. We tentatively assign it as a deep trap state, which suggests that the improved conversion efficiency of M:BiVO4 relative to the undoped material is largely due to the increased carrier concentration in spite of increased carrier recombination rates.
    Keywords absorption ; anodes ; bismuth ; crystals ; electrochemistry ; energy ; molybdenum ; oxygen ; photochemistry ; spectral analysis ; X-radiation ; X-ray absorption spectroscopy ; X-ray scattering
    Language English
    Dates of publication 2015-1124
    Size p. 23743-23753.
    Publishing place The Royal Society of Chemistry
    Document type Article
    ZDB-ID 2702232-8
    ISSN 2050-7496 ; 2050-7488
    ISSN (online) 2050-7496
    ISSN 2050-7488
    DOI 10.1039/c5ta07898a
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Effect of adrenocortical hormones on serum proteins of adrenalectomized mice infected with M. tuberculosis.

    SCHULTZ, R L / OKAWAKI, M S / SEERVELD, H L / MULLINS, J S

    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

    2003  Volume 96, Issue 3, Page(s) 664–667

    MeSH term(s) Adrenal Cortex Hormones/pharmacology ; Animals ; Blood Proteins/drug effects ; Mice ; Mycobacterium tuberculosis ; Tuberculosis
    Chemical Substances Adrenal Cortex Hormones ; Blood Proteins
    Language English
    Publishing date 2003-09-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4015-0
    ISSN 1535-3699 ; 1525-1373 ; 0037-9727
    ISSN (online) 1535-3699 ; 1525-1373
    ISSN 0037-9727
    DOI 10.3181/00379727-96-23571
    Database MEDical Literature Analysis and Retrieval System OnLINE

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