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  1. Article ; Online: Hepatitis C.

    McGoldrick, Mary

    Home healthcare nurse

    2014  Volume 32, Issue 6, Page(s) 373

    MeSH term(s) Age Distribution ; Aged ; Centers for Disease Control and Prevention (U.S.) ; Disease Progression ; Female ; Hepatitis C/epidemiology ; Hepatitis C/prevention & control ; Hepatitis C, Chronic/epidemiology ; Hepatitis C, Chronic/prevention & control ; Humans ; Male ; Mass Screening/organization & administration ; Middle Aged ; Prevalence ; Sex Distribution ; United States/epidemiology
    Language English
    Publishing date 2014-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 605757-3
    ISSN 1539-0713 ; 0884-741X
    ISSN (online) 1539-0713
    ISSN 0884-741X
    DOI 10.1097/NHH.0000000000000093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Response to Shtarbanov et al paper: Raising of bi-pedicled flaps increases operative time and complications.

    Reid, L A / Hoo, C / Isaac, A / McGoldrick, C

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS

    2023  Volume 88, Page(s) 243–244

    MeSH term(s) Humans ; Operative Time ; Surgical Flaps ; Plastic Surgery Procedures/adverse effects
    Language English
    Publishing date 2023-10-17
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2217750-4
    ISSN 1878-0539 ; 1748-6815 ; 0007-1226
    ISSN (online) 1878-0539
    ISSN 1748-6815 ; 0007-1226
    DOI 10.1016/j.bjps.2023.10.057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: An assessment of the reporting of tapering methods in antidepressant discontinuation trials using the TIDieR checklist.

    McGoldrick, Amy / Byrne, Helen / Cadogan, Cathal

    International journal of clinical pharmacy

    2023  Volume 45, Issue 5, Page(s) 1074–1087

    Abstract: Background: The importance of tapering is increasingly recognised when discontinuing antidepressant medication. However, no previous studies have examined the reporting of antidepressant tapering methods in published studies.: Aim: The aim of this ... ...

    Abstract Background: The importance of tapering is increasingly recognised when discontinuing antidepressant medication. However, no previous studies have examined the reporting of antidepressant tapering methods in published studies.
    Aim: The aim of this study was to assess the completeness of reporting of antidepressant tapering methods in a published systematic review using the Template for Intervention Description and Replication (TIDieR) checklist.
    Method: A secondary analysis was conducted of studies included in a Cochrane systematic review that examined the effectiveness of approaches for discontinuing long-term antidepressant use. The completeness of reporting of antidepressant tapering methods in included studies was independently assessed by two researchers using the 12 items from the TIDieR checklist.
    Results: Twenty-two studies were included in the analysis. None of the study reports described all checklists items. No study clearly reported what materials had been provided (item 3) or whether tailoring had occurred (item 9). With the exception of providing a name for the intervention or study procedures (item 1), only a minority of studies clearly reported on any of the remaining checklist items.
    Conclusion: The findings highlight a lack of detailed reporting of antidepressant tapering methods in published trials to date. This needs to be addressed as poor reporting could hinder replication and adaptation of existing interventions, as well as the potential for successful translation of effective tapering interventions into clinical practice.
    MeSH term(s) Humans ; Checklist ; Research Design
    Language English
    Publishing date 2023-06-03
    Publishing country Netherlands
    Document type Systematic Review ; Journal Article
    ZDB-ID 2601204-2
    ISSN 2210-7711 ; 2210-7703 ; 0928-1231
    ISSN (online) 2210-7711
    ISSN 2210-7703 ; 0928-1231
    DOI 10.1007/s11096-023-01602-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Aesthetic Breast Surgery: What Do the Measurements Reveal? A Practical Visual Application of the Results.

    Bolletta, Elisa / McGoldrick, Ciara / Hall-Findlay, Elizabeth J

    Aesthetic surgery journal

    2023  Volume 43, Issue 11, Page(s) NP866–NP877

    Abstract: Background: The results of preoperative and 1-year postoperative measurements in aesthetic breast surgery were outlined in chart form in the Aesthetic Surgery Journal in 2020. Measurements were performed preoperatively and postoperatively, but the ... ...

    Abstract Background: The results of preoperative and 1-year postoperative measurements in aesthetic breast surgery were outlined in chart form in the Aesthetic Surgery Journal in 2020. Measurements were performed preoperatively and postoperatively, but the authors concentrated on 1-year follow-up because it was generally accepted as the minimum time to define a stable surgical result. Extensive statistical analysis was outlined in the previous paper.
    Objectives: This paper translates those results into a visual form so that the surgeon can see the changes that occur in breast reduction, breast augmentation, mastopexy, mastopexy-augmentation, and implant removal with mastopexy.
    Methods: There were 548 patients in the breast augmentation group, 388 patients in the breast reduction group, 244 patients for mastopexy-augmentation, and 90 patients for mastopexy. Only primary surgeries that had a full year follow-up comparing preoperative and postoperative measurements were reviewed. Measurements were performed by E.H.F. preoperatively and at each postoperative visit. The measurements that were included in this study were clavicle to upper breast border, upper breast border to nipple, suprasternal notch to nipple, suprasternal notch to inframammary fold, and midline to nipple.
    Results: The preoperative and postoperative measurement changes in aesthetic breast surgery were consistent, with minimal variation for each of the aesthetic breast surgery procedures.
    Conclusions: The visual interpretation of these results allows the surgeon to accurately plan preoperatively to achieve good, predictable results.
    MeSH term(s) Humans ; Female ; Mammaplasty/methods ; Mastectomy ; Reoperation ; Esthetics ; Breast Neoplasms ; Retrospective Studies ; Breast Implants ; Treatment Outcome
    Language English
    Publishing date 2023-07-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2087022-X
    ISSN 1527-330X ; 1090-820X ; 1084-0761
    ISSN (online) 1527-330X
    ISSN 1090-820X ; 1084-0761
    DOI 10.1093/asj/sjad243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Healthy eating index-C is positively associated with family dinner frequency among students in grades 6-8 from Southern Ontario, Canada.

    Woodruff, S J / Hanning, R M / McGoldrick, K / Brown, K S

    European journal of clinical nutrition

    2010  Volume 64, Issue 5, Page(s) 454–460

    Abstract: ... calculated using the Healthy Eating Index-C (HEI-C), which is a recently modified diet quality index ... reporting 6-7 dinners/week (HEI-C=66.2 versus 62.1 and 62.8 for 0-2 and 3-5 days/week, respectively, P<0.001 ...

    Abstract Background/objectives: Unhealthy eating behaviours may contribute to the rising prevalence of childhood obesity in Canada. The purpose of this study was to describe family dinner frequency (FDF) and its associations with overall diet quality.
    Subjects/methods: The sample included grades six (n=372), seven (n=429) and eight (n=487) students from Southern Ontario. Data were collected with the Food Behaviour Questionnaire, including a single 24-h dietary recall and questions about individual meals. Diet quality was calculated using the Healthy Eating Index-C (HEI-C), which is a recently modified diet quality index.
    Results: The majority of participants (65%) reported frequent family dinner meals (6-7 days/week versus 20% on 3-5 days/week and 15% on 0-2 days/week). Diet quality scores were higher among participants reporting 6-7 dinners/week (HEI-C=66.2 versus 62.1 and 62.8 for 0-2 and 3-5 days/week, respectively, P<0.001). Adjusted models reported that diet quality scores were also associated with whom participants consumed breakfast (P<0.001), lunch (P<0.001) and dinner (P<0.001), yet they were most strongly associated (negatively) with participants who skipped the meal altogether.
    Conclusions: Increased family dinner meals were positively associated with daily diet quality and negatively associated with breakfast and lunch skipping. Promoting family dinner meals in healthy living intervention strategies is advised.
    MeSH term(s) Child ; Child Behavior ; Cross-Sectional Studies ; Diet/standards ; Diet Records ; Diet Surveys ; Family ; Feeding Behavior ; Female ; Humans ; Male ; Obesity/etiology ; Ontario ; Social Environment ; Students ; Time Factors
    Language English
    Publishing date 2010-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639358-5
    ISSN 1476-5640 ; 0954-3007
    ISSN (online) 1476-5640
    ISSN 0954-3007
    DOI 10.1038/ejcn.2010.14
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Social Interest Data as a Proxy for Off-Label Performance-Enhancing Drug Use: Implications and Clinical Considerations.

    Holubeck, Philip A / Eksi, Andrew C / Gillett, Kyle / O'Hara, James / McGoldrick, Daniel J / Brown, Demi R / McCarthy, Alec D

    Cureus

    2024  Volume 16, Issue 1, Page(s) e52011

    Abstract: Performance-enhancing drugs (PEDs) can be categorized into various classes based on the physiological mechanism of the compound, with the most popular being anabolic steroids, selective androgen receptor modulators, and growth hormones. Ancillary ... ...

    Abstract Performance-enhancing drugs (PEDs) can be categorized into various classes based on the physiological mechanism of the compound, with the most popular being anabolic steroids, selective androgen receptor modulators, and growth hormones. Ancillary compounds, such as selective estrogen receptor modulators (SERMs) and selective estrogen receptor degraders, are commonly utilized alongside a PED to counterbalance any potential undesired side effects. With little clinically relevant data to support the use of these ancillary compounds, medical education and evidence-based approaches aimed at monitoring the potential adverse effects of PED use are sparse.This study aims to identify emerging trends in the interest of PEDs and related ancillary compounds, hypothesize the physiological effects of the continued respective behavior, and propose a proxy for use by clinicians to approximate off-label drug use and subsequently modify their practices accordingly. Several significant trends were identified for non-FDA-regulated compounds (i.e., selective androgen receptor modulators such as RAD-140) and off-label indications for FDA-regulated drugs (i.e., SERMs such as tamoxifen). A significant increase in interest regarding selective androgen receptor modulators, mirrored by anecdotal reports in clinical settings and online forums, is coupled with stagnant or decreasing interest in both post-cycle therapies and anabolic steroids. Ultimately, we propose a call to action for utilizing social data and/or prescription data as a proxy for clinicians to better understand trends in these compounds and thus refine their treatment protocols in a concordant manner.
    Language English
    Publishing date 2024-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.52011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Facing the Unknown: Idiopathic Giant Cell Hepatitis.

    McGoldrick, Meaghan / Castrodad-Rodríguez, Carlos A / Huang, Yan / Tow, Clara

    ACG case reports journal

    2023  Volume 10, Issue 1, Page(s) e00966

    Abstract: Giant cell hepatitis is a rare infiltrative disease associated with several viruses, drugs, malignancies, and autoimmune conditions. To date, treatment aims at controlling the underlying etiology, and there are limited data on the clinical course and ... ...

    Abstract Giant cell hepatitis is a rare infiltrative disease associated with several viruses, drugs, malignancies, and autoimmune conditions. To date, treatment aims at controlling the underlying etiology, and there are limited data on the clinical course and treatment of idiopathic cases. We present a case of idiopathic giant cell hepatitis in an otherwise healthy adult man and review the literature regarding treatment and outcomes in this population.
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2814825-3
    ISSN 2326-3253
    ISSN 2326-3253
    DOI 10.14309/crj.0000000000000966
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Healthy eating index-C is positively associated with family dinner frequency among students in grades 6–8 from Southern Ontario, Canada

    Woodruff, S.J / Hanning, R.M / McGoldrick, K / Brown, K.S

    European journal of clinical nutrition. 2010 May, v. 64, issue 5

    2010  

    Abstract: ... calculated using the Healthy Eating Index-C (HEI-C), which is a recently modified diet quality index. Results ... dinners/week (HEI-C=66.2 versus 62.1 and 62.8 for 0–2 and 3–5 days/week, respectively, P<0.001). Adjusted ...

    Abstract Background/Objectives: Unhealthy eating behaviours may contribute to the rising prevalence of childhood obesity in Canada. The purpose of this study was to describe family dinner frequency (FDF) and its associations with overall diet quality. Subjects/Methods: The sample included grades six (n=372), seven (n=429) and eight (n=487) students from Southern Ontario. Data were collected with the Food Behaviour Questionnaire, including a single 24-h dietary recall and questions about individual meals. Diet quality was calculated using the Healthy Eating Index-C (HEI-C), which is a recently modified diet quality index. Results: The majority of participants (65%) reported frequent family dinner meals (6–7 days/week versus 20% on 3-5 days/week and 15% on 0-2 days/week). Diet quality scores were higher among participants reporting 6-7 dinners/week (HEI-C=66.2 versus 62.1 and 62.8 for 0–2 and 3–5 days/week, respectively, P<0.001). Adjusted models reported that diet quality scores were also associated with whom participants consumed breakfast (P<0.001), lunch (P<0.001) and dinner (P<0.001), yet they were most strongly associated (negatively) with participants who skipped the meal altogether. Conclusions: Increased family dinner meals were positively associated with daily diet quality and negatively associated with breakfast and lunch skipping. Promoting family dinner meals in healthy living intervention strategies is advised.
    Keywords diet ; child nutrition ; adolescent nutrition ; school children ; adolescents ; nutritional adequacy ; eating habits ; family relations ; dinner ; breakfast ; boys ; girls ; gender differences ; age ; body weight ; Ontario
    Language English
    Dates of publication 2010-05
    Size p. 454-460.
    Document type Article
    ZDB-ID 639358-5
    ISSN 1476-5640 ; 0954-3007
    ISSN (online) 1476-5640
    ISSN 0954-3007
    DOI 10.1038/ejcn.2010.14
    Database NAL-Catalogue (AGRICOLA)

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  9. Article ; Online: Evaluation of an online advanced suicide prevention training for pharmacists.

    Pilbrow, Samantha / Staniland, Lexy / Uren, Hannah V / Shand, Fiona / McGoldrick, Janey / Thorp, Emily / MacKrill, Monique / Moullin, Joanna C

    International journal of clinical pharmacy

    2023  Volume 45, Issue 5, Page(s) 1203–1211

    Abstract: Background: With the pharmacist role extending internationally to include health promotion and harm reduction, pharmacists are well-suited to adopt a frontline role within suicide prevention efforts. To maximise their abilities to implement suicide ... ...

    Abstract Background: With the pharmacist role extending internationally to include health promotion and harm reduction, pharmacists are well-suited to adopt a frontline role within suicide prevention efforts. To maximise their abilities to implement suicide prevention strategies, suicide prevention training is essential to improve pharmacists' knowledge of, attitudes towards, and confidence in pharmacy-based suicide prevention.
    Aim: This study aimed to evaluate the impact of an online Advanced Suicide Prevention Training for Pharmacists and explore how participant feedback may direct training improvements.
    Method: One hundred and fifty pharmacists in Tasmania, Australia, completed the training. Of these, 109 participants completed surveys pre-, post- and 6-months post-training to evaluate changes in suicide prevention knowledge, confidence, and attitudes, and explore participants' perceptions of the training.
    Results: Significant improvements were observed in suicide prevention attitudes (F(2, 20) = 4.12, p = 0.032, partial η
    Conclusion: Training is an effective means of improving pharmacists' suicide prevention knowledge, confidence, and attitudes. While personal barriers to suicide prevention improved, contextual and social barriers continue to impede pharmacists' implementation of suicide prevention in practice.
    MeSH term(s) Humans ; Pharmacists ; Suicide Prevention ; Pharmacy ; Australia ; Community Pharmacy Services ; Attitude of Health Personnel ; Professional Role
    Language English
    Publishing date 2023-09-13
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2601204-2
    ISSN 2210-7711 ; 2210-7703 ; 0928-1231
    ISSN (online) 2210-7711
    ISSN 2210-7703 ; 0928-1231
    DOI 10.1007/s11096-023-01636-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Understanding the Role of Biofilms in Acute Recurrent Tonsillitis through 3D Bioprinting of a Novel Gelatin-PEGDA Hydrogel.

    Denton, Oliver / Wan, Yifei / Beattie, Laura / Jack, Téa / McGoldrick, Preston / McAllister, Holly / Mullan, Cara / Douglas, Catriona M / Shu, Wenmiao

    Bioengineering (Basel, Switzerland)

    2024  Volume 11, Issue 3

    Abstract: ... computer-aided design to mimic the tonsillar biofilm environment. The bioprinted constructs were cultured at 37 °C ...

    Abstract Acute recurrent tonsillitis is a chronic, biofilm-related infection that is a significant burden to patients and healthcare systems. It is often treated with repeated courses of antibiotics, which contributes to antimicrobial resistance. Studying biofilms is key to understanding this disease. In vitro modelling using 3D bioprinted hydrogels is a promising approach to achieve this. A novel gelatin-PEGDA pseudomonas fluorescens-laden bioink was developed and bioprinted in a 3D hydrogel construct fabricated using computer-aided design to mimic the tonsillar biofilm environment. The bioprinted constructs were cultured at 37 °C in lysogeny broth for 12 days. Bacterial growth was assessed by spectrophotometry. Cellular viability analysis was conducted using optical fluorescence microscopy (FDA/PI staining). A biocompatible 3D-printed bacteria-laden hydrogel construct was successfully fabricated. Bacterial growth was observed using optical fluorescence microscopy. A live/dead cellular-staining protocol demonstrated bacterial viability. Results obtained after the 12-day culture period showed higher bacterial growth in the 1% gelatin concentration construct compared to the 0% control. This study demonstrates the first use of a bacteria-laden gelatin-PEGDA hydrogel for biofabrication of a 3D-printed construct designed to model acute recurrent tonsillitis. Initiating a study with clinically relevant ex vivo tonsil bacteria will be an important next step in improving treatment of this impactful but understudied disease.
    Language English
    Publishing date 2024-02-21
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2746191-9
    ISSN 2306-5354
    ISSN 2306-5354
    DOI 10.3390/bioengineering11030202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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