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  1. Article ; Online: Reply to A. Braillon, M. Boulin et al, and J.-H. Zhong et al.

    Brown, Karen T / Do, Richard / Gönen, Mithat / Covey, Anne M / Getrajdman, George I / Sofocleous, Constantinos T / Jarnagin, William R / D'Angelica, Michael I / Allen, Peter J / Erinjeri, Joseph P / Brody, Lynn A / O'Neill, Gerald P / Johnson, Kristian / Garcia, Alessandra R / Beattie, Christopher M / Zhao, Binsheng / Solomon, Stephen B / Schwartz, Lawrence H / DeMatteo, Ronald P /
    Abou-Alfa, Ghassan K

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2016  Volume 35, Issue 2, Page(s) 258–259

    MeSH term(s) Carcinoma, Hepatocellular ; Embolization, Therapeutic ; Humans ; Liver Neoplasms
    Language English
    Publishing date 2016-10-23
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.2016.69.7961
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reply to B. Bennani-Baiti et al, H.J.A. Adams et al, E. Laffon et al, and E.A. Hawkes et al.

    Barrington, Sally F / Mikhaeel, N George / Kostakoglu, Lale / Meignan, Michel / Hutchings, Martin / Müeller, Stefan / Schwartz, Lawrence H / Zucca, Emanuele / Fisher, Richard I / Trotman, Judith / Hoekstra, Otto S / Hicks, Rodney J / O'Doherty, Michael J / Hustinx, Roland / Biggi, Alberto / Cavalli, Franco / Lister, T Andrew / Cheson, Bruce D

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2015  Volume 33, Issue 10, Page(s) 1221–1223

    MeSH term(s) Fluorodeoxyglucose F18 ; Humans ; Lymphoma/diagnostic imaging ; Lymphoma/therapy ; Positron-Emission Tomography ; Radiopharmaceuticals ; Tomography, X-Ray Computed
    Chemical Substances Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
    Language English
    Publishing date 2015-04-01
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.2014.59.9373
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Synthesis and characterization of membrane immunoglobulin, Ia, and H-2 molecules of thy 1+ AKR/J lymphomas.

    Schwartz, B D / Campbell, P S / Asofsky, R / Greenberg, R S / Zatz, M M

    Journal of immunology (Baltimore, Md. : 1950)

    1977  Volume 119, Issue 5, Page(s) 1706–1710

    Abstract: ... Because of the proclivity of normal AKR/J mice to develop T cell lymphomas, and the rarity of lymphomas with dual ...

    Abstract Three AKR lymphomas displaying B cell and T cell characteristics have been described. Because of the proclivity of normal AKR/J mice to develop T cell lymphomas, and the rarity of lymphomas with dual characteristics, the B cell markers of these tumors were studied more intensively. Fluorescence data with class-specific anti-immunoglobulin reagents demonstrated that the tumor cells stained only with class-specific anti-IgM reagents. Because of the possibility that the surface Ig was passively acquired and of reports that certain anti-mu-chain sera react with "IgT", chemical characterization of the immunoglobulin molecules was performed. Using 3H-leucine internal labeling, we showed that all three tumor lines synthesized the immunoglobulin found on their surface, and that the immunoglobulin had the chemical and immunologic characteristics most typical of monomeric surface IgM, and was composed of mu-chains and light chains. The Ia antigens found on these cells were also examined. These antigens were also synthesized by the cells and were present in the same molecular form and in the same approximate quantity as Ia antigens on normal spleen cells.
    MeSH term(s) Animals ; B-Lymphocytes/immunology ; Cell Membrane/immunology ; Electrophoresis, Polyacrylamide Gel ; H-2 Antigens/isolation & purification ; Immunodiffusion ; Immunoglobulin M/isolation & purification ; Isoantigens/isolation & purification ; Lymphoma/immunology ; Mice ; Mice, Inbred AKR ; Neoplasm Transplantation ; Neoplasms, Experimental/immunology ; Receptors, Antigen, B-Cell/isolation & purification ; T-Lymphocytes/immunology
    Chemical Substances H-2 Antigens ; Immunoglobulin M ; Isoantigens ; Receptors, Antigen, B-Cell
    Language English
    Publishing date 1977-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3056-9
    ISSN 1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
    ISSN (online) 1550-6606
    ISSN 0022-1767 ; 1048-3233 ; 1047-7381
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Demonstrating the utility of Instrumented Gait Analysis in the treatment of children with cerebral palsy.

    Schwartz, Michael H / Ries, Andrew J / Georgiadis, Andrew G / Kainz, Hans

    PloS one

    2024  Volume 19, Issue 4, Page(s) e0301230

    Abstract: Background: Instrumented gait analysis (IGA) has been around for a long time but has never been shown to be useful for improving patient outcomes. In this study we demonstrate the potential utility of IGA by showing that machine learning models are ... ...

    Abstract Background: Instrumented gait analysis (IGA) has been around for a long time but has never been shown to be useful for improving patient outcomes. In this study we demonstrate the potential utility of IGA by showing that machine learning models are better able to estimate treatment outcomes when they include both IGA and clinical (CLI) features compared to when they include CLI features alone.
    Design: We carried out a retrospective analysis of data from ambulatory children diagnosed with cerebral palsy who were seen at least twice at our gait analysis center. Individuals underwent a variety of treatments (including no treatment) between sequential gait analyses. We fit Bayesian Additive Regression Tree (BART) models that estimated outcomes for mean stance foot progression to demonstrate the approach. We built two models: one using CLI features only, and one using CLI and IGA features. We then compared the models' performance in detail. We performed similar, but less detailed, analyses for a number of other outcomes. All results were based on independent test data from a 70%/30% training/testing split.
    Results: The IGA model was more accurate than the CLI model for mean stance-phase foot progression outcomes (RMSEIGA = 11∘, RMSECLI = 13∘) and explained more than 1.5 × as much of the variance (R2IGA = .45, R2CLI = .28). The IGA model outperformed the CLI model for every level of treatment complexity, as measured by number of simultaneous surgeries. The IGA model also exhibited superior performance for estimating outcomes of mean stance-phase knee flexion, mean stance-phase ankle dorsiflexion, maximum swing-phase knee flexion, gait deviation index (GDI), and dimensionless speed.
    Interpretation: The results show that IGA has the potential to be useful in the treatment planning process for ambulatory children diagnosed with cerebral palsy. We propose that the results of machine learning outcome estimators-including estimates of uncertainty-become the primary IGA tool utilized in the clinical process, complementing the standard medical practice of conducting a through patient history and physical exam, eliciting patient goals, reviewing relevant imaging data, and so on.
    MeSH term(s) Child ; Humans ; Gait Analysis ; Retrospective Studies ; Cerebral Palsy/surgery ; Bayes Theorem ; Gait ; Range of Motion, Articular ; Immunoglobulin A ; Biomechanical Phenomena ; Gait Disorders, Neurologic/therapy
    Chemical Substances Immunoglobulin A
    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0301230
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Reflections on Sandy Hook: a Decade Later.

    Sukhera, Javeed / Schwartz, Harold

    Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

    2023  Volume 47, Issue 5, Page(s) 486–487

    Language English
    Publishing date 2023-05-16
    Publishing country United States
    Document type Editorial
    ZDB-ID 1045331-3
    ISSN 1545-7230 ; 1042-9670
    ISSN (online) 1545-7230
    ISSN 1042-9670
    DOI 10.1007/s40596-023-01792-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: C-Reactive Protein Does Not Predict Future Depression Onset in Adolescents: Preliminary Findings from a Longitudinal Study.

    Schwartz, Joshua J / Roske, Chloe / Liu, Qi / Tobe, Russel H / Ely, Benjamin A / Gabbay, Vilma

    Journal of child and adolescent psychopharmacology

    2024  

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-04-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1055410-5
    ISSN 1557-8992 ; 1044-5463
    ISSN (online) 1557-8992
    ISSN 1044-5463
    DOI 10.1089/cap.2023.0091
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [Besprechung von:] Daus, P. H., and W. W. Whyburn: Algebra with applications to business and economics. London 1961 - Yamane, T.: Mathematics for economists: An elementary survey. Englewood Cliffs, N. J. 1962 - Schwartz, J. T.: Lectures on the mathematical method in analytical economics. New York 1961

    Kade, Gerhard / Daus, P. H / Schwartz, J. T / Whyburn, W. W / Yamane, T

    Jahrbücher für Nationalökonomie und Statistik Vol. 175, No. 3 , p. 278-279

    1963  Volume 175, Issue 3, Page(s) 278–279

    Author's details Gerhard Kade
    Publisher Lucius und Lucius
    Publishing place Stuttgart
    Document type Article
    ZDB-ID 215643x
    Database ECONomics Information System

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  8. Article ; Online: Soft tissue displacement for detection of left ventricle apical dyskinesis with transthoracic echocardiography.

    Schwartz, Brandon H / Tamarappoo, Balaji K / Shmueli, Hezzy / Siegel, Robert J

    The international journal of cardiovascular imaging

    2023  Volume 39, Issue 8, Page(s) 1425–1430

    Abstract: We tested the hypothesis that the use of outward displacement of the soft tissue between the apex and the chest wall as seen in TTE, is a sign of apical displacement and would allow for more accurate diagnosis of apical dyskinesis. This is a ... ...

    Abstract We tested the hypothesis that the use of outward displacement of the soft tissue between the apex and the chest wall as seen in TTE, is a sign of apical displacement and would allow for more accurate diagnosis of apical dyskinesis. This is a retrospective study of 123 patients who underwent TTE and cardiac magnetic resonance imaging (MRI) within a time frame of 6 months between 2008 and 2019. 110 subjects were deemed to have good quality studies and included in the final analysis. An observer blinded to the study objectives evaluated the echocardiograms and recorded the presence or absence of apical dyskinesis. Two independent observers evaluated the echocardiograms based on the presence or absence of outward displacement of the overlying tissue at the LV apex. Cardiac MRI was used to validate the presence of apical dyskinesis. The proportion of studies which were identified as having apical dyskinesis with conventional criteria defined as outward movement of the left ventricular apex during systole were compared to those deemed to have dyskinesis based on tissue displacement. By cardiac MRI, 90 patients had apical dyskinesis. Using conventional criteria on TTE interpretation, 21 were diagnosed with apical dyskinesis (23.3%). However, when soft tissue displacement was used as the diagnostic marker of dyskinesis, 78 patients (86.7%) were diagnosed with dyskinesis, p < 0.01. Detection of displacement of soft tissue overlying the LV apex facilitates better recognition of LV apical dyskinesis.
    MeSH term(s) Humans ; Heart Ventricles/diagnostic imaging ; Heart Ventricles/pathology ; Retrospective Studies ; Predictive Value of Tests ; Echocardiography/methods ; Heart ; Ventricular Function, Left
    Language English
    Publishing date 2023-05-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2055311-0
    ISSN 1875-8312 ; 1573-0743 ; 1569-5794 ; 0167-9899
    ISSN (online) 1875-8312 ; 1573-0743
    ISSN 1569-5794 ; 0167-9899
    DOI 10.1007/s10554-023-02856-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A patella marker to improve hip and knee kinematics for models with functionally defined joint axes.

    Ries, Andrew J / Schwartz, Michael H

    Gait & posture

    2021  Volume 87, Page(s) 43–48

    Abstract: Background: The clinical utility of motion capture modeling relies on the accurate tracking of segment motions. Soft tissue artefact presents a particular challenge for modeling hip rotation, knee rotation, and knee varus-valgus motions. The integration ...

    Abstract Background: The clinical utility of motion capture modeling relies on the accurate tracking of segment motions. Soft tissue artefact presents a particular challenge for modeling hip rotation, knee rotation, and knee varus-valgus motions. The integration of a patella marker has been shown to significantly improve hip rotation tracking for models that utilize anatomical definitions of joint axes (e.g. anatomical models). However, these modeling improvements have not been extended to models that use functional segment motion to define joint axes (e.g. functional models).
    Research question: How does the positioning of a patella marker influence functional model performance?
    Methods: A patella functional model (PFM) was created by integrating a patella marker into the functional model (FM) used at our center. Nine distinct versions of the PFM were created using a 3 × 3 grid of markers placed across the patella. Ten typically developing participants performed controlled hip rotation, controlled knee flexion-extension, and free speed walking trials to assess FM and PFM performance differences.
    Results: The top performing PFM modeled 98 ± 8 % of the reference hip rotation range of motion compared to 71 ± 9 % for the FM. This PFM had low sensitivity to knee flexion-extension motion, 5 ± 10 %. For walking kinematics, this top performing PFM reported 14 % greater hip rotation ROM during stance, 46 % less knee rotation ROM over the entire gait cycle, and 32 % less knee varus-valgus during swing compared to the FM. The differences in modeling are nearly identical to those reported between skin mounted marker and fluoroscopy-based models, indicating that utilization of the patella marker leads to improvements in tracking accuracy.
    Significance: Utilization of a precisely placed patella marker led to substantial improvements in modeled hip rotation, knee rotation, and knee varus-valgus. These improvements have the potential to positively impact those specialties that rely on motion capture modeling for clinical decision-making, such as orthopedic surgery.
    MeSH term(s) Biomechanical Phenomena ; Hip Joint ; Humans ; Knee Joint ; Patella ; Range of Motion, Articular ; Rotation ; Walking
    Language English
    Publishing date 2021-04-14
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1162323-8
    ISSN 1879-2219 ; 0966-6362
    ISSN (online) 1879-2219
    ISSN 0966-6362
    DOI 10.1016/j.gaitpost.2021.04.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Current spread of the grapevine yellows and characterization methods for the MLO pathogen (in: Stanek, G., Cassel, G. H., Tully, J. G., Whitcomb, R. F. (Eds.): Recent Advances in Mycoplasmology. Proceedings of the 7th Congress of the International Organization for Mycoplasmology, Baden near Vienna, 1988)

    Caudwell, A. / Padieu, E. / Lherminier, J. / Schwartz, Y. / Meignoz, R.

    Zentralblatt fuer Bakteriologie

    1990  Volume Supplement, Page(s) Supplement 20 916–918

    Abstract: This study shows that ELISA can be used to identify leafhoppers (Scaphoideus littoralis) carrying the mycoplasma-like organism (MLO) which causes flavescence doree (FD). It was also effective in identifying FD in cuttings collected in winter from ... ...

    Abstract This study shows that ELISA can be used to identify leafhoppers (Scaphoideus littoralis) carrying the mycoplasma-like organism (MLO) which causes flavescence doree (FD). It was also effective in identifying FD in cuttings collected in winter from infected vineyards and grown under glasshouse conditions and gave a positive response in cuttings following controlled feeding by the leafhopper. It was not effective in identifying FD in field samples of infected vines collected during symptom development in summer. (M. Barlass, Adelaide) [10344]
    Keywords flavescence doree ; detection ; vector ; transmission ; france
    Language English
    Document type Article
    Database Viticulture and Oenology Abstracts

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