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Article ; Online: Parkinsonism in GPi-DBS for Dystonia; When to Suspect Degenerative Parkinsonism?

Swinnen, B E K S / Beudel, M / Schuurman, P R / de Bie, R M A

Movement disorders clinical practice

2022 Volume 9, Issue 7, Page(s) 990–991

Language	English
Publishing date	2022-09-08
Publishing country	United States
Document type	Journal Article
ISSN	2330-1619
ISSN (online)	2330-1619
DOI	10.1002/mdc3.13552
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Article ; Online: Reply. Beyond the plate: exploring the complexities of using dietary approaches to manage endometriosis.

van Haaps, A P / Wijbers, J V / Schreurs, A M F / Vlek, S / Tuynman, J / De Bie, B / de Vogel, A L / van Wely, M / Mijatovic, V

Human reproduction (Oxford, England)

2024 Volume 39, Issue 4, Page(s) 865–866

MeSH term(s)	Female ; Humans ; Endometriosis/surgery ; Diet
Language	English
Publishing date	2024-02-17
Publishing country	England
Document type	Journal Article
ZDB-ID	632776-x
ISSN	1460-2350 ; 0268-1161 ; 1477-741X
ISSN (online)	1460-2350
ISSN	0268-1161 ; 1477-741X
DOI	10.1093/humrep/deae021
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Article ; Online: Exercise- and education-based prehabilitation before total knee arthroplasty: a pilot study.

Gränicher, Pascale / Mulder, Loes / Lenssen, Ton / Fucentese, Sandro F / Swanenburg, Jaap / De Bie, Rob / Scherr, Johannes

Journal of rehabilitation medicine

2024 Volume 56, Page(s) jrm18326

Abstract: ... subscale of the Knee Osteoarthritis Outcome Score (F(3/54) = 2.895, p = 0.043, η² = 0.139) and Tegner ... Activity Scale (F(2.2/39.1) = 3.20, p = 0.048, η² = 0.151).: Conclusion: The absence of adverse events ...

Abstract	Objective: To determine the feasibility and estimates of effects of a supervised exercise- and education-based prehabilitation programme aiming to improve knee functioning compared with usual care in patients awaiting total knee arthroplasty. Design: A randomized controlled pilot study. Subjects: Patients receiving primary, unilateral total knee arthroplasty. Methods: Patients randomized to the intervention group participated in a personalized 4-8-week prehabilitation programme before surgery. Feasibility of the intervention and self-reported knee functioning, pain, physical performance and hospital stay were assessed at baseline, immediately preoperatively, 6 and 12 weeks after surgery. Results: Twenty patients (mean age 72.7±5.95 years) were enrolled in this study. The personalized prehabilitation programme was found to be feasible and safe, with an exercise adherence of 90%. Significant medium interaction effects between groups and over time favouring prehabilitation were reported for the sport subscale of the Knee Osteoarthritis Outcome Score (F(3/54) = 2.895, p = 0.043, η² = 0.139) and Tegner Activity Scale (F(2.2/39.1) = 3.20, p = 0.048, η² = 0.151). Conclusion: The absence of adverse events and high adherence to the programme, coupled with beneficial changes shown in the intervention group, support the conduct of a full-scale trial investigating the effectiveness of prehabilitation.
MeSH term(s)	Humans ; Aged ; Preoperative Exercise ; Pilot Projects ; Arthroplasty, Replacement, Knee ; Exercise ; Knee Joint
Language	English
Publishing date	2024-01-08
Publishing country	Sweden
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2039427-5
ISSN	1651-2081 ; 1651-2235 ; 0891-060X ; 1650-1977
ISSN (online)	1651-2081 ; 1651-2235
ISSN	0891-060X ; 1650-1977
DOI	10.2340/jrm.v56.18326
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Article ; Online: Bidirectional Interplay between Deep Brain Stimulation and Cognition in Parkinson's Disease: A Systematic Review.

Sisodia, Vibuthi / Malekzadeh, Arjan / Verwijk, Esmée / Schuurman, P Richard / de Bie, Rob M A / Swinnen, Bart E K S

Movement disorders : official journal of the Movement Disorder Society

2024

Abstract: Background: Deep brain stimulation (DBS) is efficacious for treating motor symptoms in Parkinson's disease (PD).: Objectives: The aim is to evaluate the evidence regarding DBS effectiveness after postoperative cognitive deterioration, the impact of ... ...

Abstract	Background: Deep brain stimulation (DBS) is efficacious for treating motor symptoms in Parkinson's disease (PD). Objectives: The aim is to evaluate the evidence regarding DBS effectiveness after postoperative cognitive deterioration, the impact of preoperative cognition on DBS effectiveness, and the impact of DBS on cognition. Methods: Literature searches were performed on MEDLINE, EMBASE, and CENTRAL (Cochrane library). Primary outcomes were OFF-drug Unified Parkinson Disease Rating Scale Part III score and cognitive test scores. Results: DBS effectiveness did not differ in patients with postoperative declining compared to stable cognition (n = 5 studies). Preoperative cognition did not influence DBS effectiveness (n = 1 study). DBS moderately decreased verbal fluency compared to the best medical treatment (n = 24 studies), which may be transient. Conclusion: DBS motor effectiveness in PD does not appear to be influenced by cognition. DBS in PD seems cognitively safe, except for a moderate decline in verbal fluency. Further research is warranted. © 2024 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Language	English
Publishing date	2024-03-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	607633-6
ISSN	1531-8257 ; 0885-3185
ISSN (online)	1531-8257
ISSN	0885-3185
DOI	10.1002/mds.29772
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Article ; Online: Predicting Delayed In-Hospital Recovery of Physical Function After Total Knee Arthroplasty.

Mulder, Louisa T M A / Berghmans, Danielle D P / Feczko, Peter Z / van Kuijk, Sander M J / de Bie, Rob A / Lenssen, Antoine F

Archives of rehabilitation research and clinical translation

2024 Volume 6, Issue 1, Page(s) 100321

Abstract: ... modeling was applied to develop the initial model. A low de Morton Mobility Index (DEMMI), walking aid use ...

Abstract	Objective: To identify patients at high risk of delayed in-hospital functional recovery after knee replacement surgery by developing and validating a prediction model, including a combination of preoperative physical fitness parameters and patient characteristics. Design: Retrospective cohort study using binary logistic regression. Setting: University hospital, orthopedic department. Participants: 260 adults (N=260) (≥18y) with knee osteoarthritis awaiting primary unilateral total knee arthroplasty and assessed during usual care between 2016 and 2020. Intervention: Not applicable. Main outcome measures: Time to reach in-hospital functional independence (in days), measured by the modified Iowa Level of Assistance Scale. A score of 0 means completely independent. Potential predictor variables are a combination of preoperative physical fitness parameters and patient characteristics. Results: Binary logistic regression modeling was applied to develop the initial model. A low de Morton Mobility Index (DEMMI), walking aid use indoors, and a low handgrip strength (HGS) were the most important predictors of delayed in-hospital recovery. This model was internally validated and had an optimism-corrected Conclusions: The model has a low predictive value and a poor discriminative ability. However, there is a positive association between preoperative physical fitness and postoperative recovery of physical function. The validity of our model to distinguish between high and low risk, based on preoperative fitness values and patient characteristics, is limited.
Language	English
Publishing date	2024-01-20
Publishing country	United States
Document type	Journal Article
ISSN	2590-1095
ISSN (online)	2590-1095
DOI	10.1016/j.arrct.2024.100321
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Book ; Online: Risk management in projects

de Bie, P.A.F.

WI0033 WEnR

2019

Keywords	Life Science
Publisher	Wageningen Environmental Research
Publishing country	nl
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Advanced practice providers in critical care improve team performances. A post-hoc analysis of the BASIC trial.

Kreeftenberg, H G / de Bie, A J R / Subbe, C P / van der Voort, P H J

Resuscitation

2021 Volume 170, Page(s) 207–208

MeSH term(s)	Critical Care ; Humans ; Patient Care Team
Language	English
Publishing date	2021-12-14
Publishing country	Ireland
Document type	Letter
ZDB-ID	189901-6
ISSN	1873-1570 ; 0300-9572
ISSN (online)	1873-1570
ISSN	0300-9572
DOI	10.1016/j.resuscitation.2021.12.012
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Article: Thyroid stimulating immunoglobulin concentration is associated with disease activity and predicts response to treatment with intravenous methylprednisolone in patients with Graves' orbitopathy.

Hötte, Gijsbert J / Kolijn, P Martijn / de Bie, Maaike / de Keizer, Ronald O B / Medici, Marco / van der Weerd, Kim / van Hagen, P Martin / Paridaens, Dion / Dik, Willem A

Frontiers in endocrinology

2024 Volume 15, Page(s) 1340415

Abstract: ... from patient files.: Results: Higher sIL-2R levels were observed in GO patients compared to controls (p < 0 ...

Abstract	Background: Thyroid stimulating immunoglobulins (TSI) play a central role in the pathogenesis of Graves' orbitopathy (GO), while soluble interleukin-2 receptor (sIL-2R) is a marker for T-cell activity. We investigated TSI and sIL-2R levels in relation to thyroid function, disease activity and severity and response to treatment with intravenous methylprednisolone (IVMP) in patients with GO. Methods: TSI (bridge-based TSI binding assay), sIL-2R, TSH and fT4 levels were measured in biobank serum samples from 111 GO patients (37 male, 74 female; mean age 49.2 years old) and 25 healthy controls (5 male, 20 female; mean age 39.8 years old). Clinical characteristics and response to treatment were retrospectively retrieved from patient files. Results: Higher sIL-2R levels were observed in GO patients compared to controls (p < 0.001). sIL-2R correlated with fT4 ( Conclusions: High TSI levels are associated with active disease (cut-off 2.62 IU/L) and predict poor response to IVMP treatment (cut-off 19.4 IU/L) in GO. While sIL-2R correlates with disease activity, it is also related to thyroid function, making it less useful as an additional biomarker in GO.
MeSH term(s)	Humans ; Male ; Female ; Middle Aged ; Adult ; Immunoglobulins, Thyroid-Stimulating ; Graves Ophthalmopathy/drug therapy ; Retrospective Studies ; Receptors, Thyrotropin ; Thyrotropin
Chemical Substances	Immunoglobulins, Thyroid-Stimulating ; Receptors, Thyrotropin ; Thyrotropin (9002-71-5)
Language	English
Publishing date	2024-03-21
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2592084-4
ISSN	1664-2392
ISSN	1664-2392
DOI	10.3389/fendo.2024.1340415
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Article ; Online: A multicenter double-blind randomized crossover study comparing the impact of dorsal subthalamic nucleus deep brain stimulation versus standard care on apathy in Parkinson's disease: a study protocol.

Zoon, T J C / van Rooijen, G / Contarino, M F / van der Gaag, S / Zutt, R / van Asseldonk, J T / van den Munckhof, P / Schuurman, P R / Denys, D A J P / de Bie, R M A

Trials

2024 Volume 25, Issue 1, Page(s) 104

Abstract: Background: Neuroimaging studies suggest an association between apathy after deep brain stimulation (DBS) and stimulation of the ventral part of the subthalamic nucleus (STN) due to the associative fibers connected to the non-motor limbic circuits that ... ...

Abstract	Background: Neuroimaging studies suggest an association between apathy after deep brain stimulation (DBS) and stimulation of the ventral part of the subthalamic nucleus (STN) due to the associative fibers connected to the non-motor limbic circuits that are involved in emotion regulation and motivation. We have previously described three patients with severe apathy that could be fully treated after switching stimulation from a ventral electrode contact point to a more dorsal contact point. Objectives: To determine whether more dorsal stimulation of the STN decreases apathy compared to standard care in a multicenter randomized controlled trial with a crossover design. Methods: We will include 26 patients with a Starkstein Apathy Scale (SAS) score of 14 or more after subthalamic nucleus (STN) deep brain stimulation (DBS) for refractory Parkinson's disease. This is a multicenter trial conducted in two teaching hospitals and one university medical center in the Netherlands after at least 3 months of STN DBS. Our intervention will consist of 1 month of unilateral dorsal STN stimulation compared to treatment as usual. The primary outcome is a change in SAS score following 1 month of DBS on the original contact compared to the SAS score following 1 month of DBS on the more dorsal contact. Secondary outcomes are symptom changes on the Movement Disorders Society-Unified Parkinson's Disease Rating Scale motor part III, Montgomery-Åsberg Depression Rating Scale, 39-item Parkinson's disease questionnaire, Parkinson's disease impulsive-compulsive disorders questionnaire, changes in levodopa-equivalent daily dosage, apathy rated by the caregiver, and burden and quality of life of the caregiver. Trial registration: ClinicalTrials.gov NL8279. Registered on January 10, 2020.
MeSH term(s)	Humans ; Parkinson Disease/therapy ; Parkinson Disease/psychology ; Subthalamic Nucleus ; Apathy ; Cross-Over Studies ; Deep Brain Stimulation/adverse effects ; Deep Brain Stimulation/methods ; Quality of Life ; Treatment Outcome ; Randomized Controlled Trials as Topic ; Multicenter Studies as Topic
Language	English
Publishing date	2024-02-03
Publishing country	England
Document type	Clinical Trial Protocol ; Journal Article
ZDB-ID	2040523-6
ISSN	1745-6215 ; 1468-6694 ; 1745-6215
ISSN (online)	1745-6215
ISSN	1468-6694 ; 1745-6215
DOI	10.1186/s13063-024-07938-9
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Article: Evaluation of the accuracy of established patient inspiratory effort estimation methods during mechanical support ventilation.

van Diepen, A / Bakkes, T H G F / De Bie, A J R / Turco, S / Bouwman, R A / Woerlee, P H / Mischi, M

Heliyon

2023 Volume 9, Issue 2, Page(s) e13610

Abstract: There is a clinical need for monitoring inspiratory effort to prevent lung- and diaphragm injury in patients who receive supportive mechanical ventilation in an Intensive Care Unit. Different pressure-based techniques are available to estimate this ... ...

Abstract	There is a clinical need for monitoring inspiratory effort to prevent lung- and diaphragm injury in patients who receive supportive mechanical ventilation in an Intensive Care Unit. Different pressure-based techniques are available to estimate this inspiratory effort at the bedside, but the accuracy of their effort estimation is uncertain since they are all based on a simplified linear model of the respiratory system, which omits gas compressibility of air, and the viscoelasticity and nonlinearities of the respiratory system. The aim of this in-silico study was to provide an overview of the pressure-based estimation techniques and to evaluate their accuracy using a more sophisticated model of the respiratory system and ventilator. The influence of the following parameters on the accuracy of the pressure-based estimation techniques was evaluated using the in-silico model: 1) the patient's respiratory mechanics 2) PEEP and the inspiratory pressure of the ventilator 3) gas compressibility of air 4) viscoelasticity of the respiratory system 5) the strength of the inspiratory effort. The best-performing technique in terms of accuracy was the whole breath occlusion. The average error and maximum error were the lowest for all patient archetypes. We found that the error was related to the expansion of gas in the breathing set and lungs and respiratory compliance. However, concerns exist that other factors not included in the model, such as a changed muscle-force relation during an occlusion, might influence the true accuracy. The estimation techniques based on the esophageal pressure showed an error related to the viscoelastic element in the model which leads to a higher error than the occlusion. The error of the esophageal pressure-based techniques is therefore highly dependent on the pathology of the patient and the settings of the ventilator and might change over time while a patient recovers or becomes more ill.
Language	English
Publishing date	2023-02-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e13610
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