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  1. Article ; Online: Lipoprotein turnover and possible remnant accumulation in preeclampsia: insights from the Freiburg Preeclampsia H.E.L.P.-apheresis study.

    Contini, Christine / Jansen, Martin / König, Brigitte / Markfeld-Erol, Filiz / Kunze, Mirjam / Zschiedrich, Stefan / Massing, Ulrich / Merfort, Irmgard / Prömpeler, Heinrich / Pecks, Ulrich / Winkler, Karl / Pütz, Gerhard

    Lipids in health and disease

    2018  Volume 17, Issue 1, Page(s) 49

    Abstract: ... for preeclamptic lipid metabolism are discussed.: Methods: In the Freiburg H.E.L.P.-Apheresis Study, 6 early ...

    Abstract Background: Preeclampsia is a life-threatening disease in pregnancy, and its complex pathomechanisms are poorly understood. In preeclampsia, lipid metabolism is substantially altered. In late onset preeclampsia, remnant removal disease like lipoprotein profiles have been observed. Lipid apheresis is currently being explored as a possible therapeutic approach to prolong preeclamptic pregnancies. Here, apheresis-induced changes in serum lipid parameters are analyzed in detail and their implications for preeclamptic lipid metabolism are discussed.
    Methods: In the Freiburg H.E.L.P.-Apheresis Study, 6 early onset preeclamptic patients underwent repeated apheresis treatments. Serum lipids pre- and post-apheresis and during lipid rebound were analyzed in depth via ultracentrifugation to yield lipoprotein subclasses.
    Results: The net elimination of Apolipoprotein B and plasma lipids was lower than theoretically expected. Lipids returned to previous pre-apheresis levels before the next apheresis even though apheresis was repeated within 2.9 ± 1.2 days. Apparent fractional catabolic rates and synthetic rates were substantially elevated, with fractional catabolic rates for Apolipoprotein B / LDL-cholesterol being 0.7 ± 0.3 / 0.4 ± 0.2 [day
    Conclusion: Lipid metabolism seems to be highly accelerated in preeclampsia, likely outbalancing remnant removal mechanisms. Since cholesterol-rich lipoprotein remnants are able to accumulate in the vessel wall, remnant lipoproteins may contribute to the severe endothelial dysfunction observed in preeclampsia.
    Trial registration: ClinicalTrails.gov, NCT01967355 .
    MeSH term(s) Adult ; Apolipoproteins B/blood ; Blood Component Removal ; Cholesterol/blood ; Cholesterol, LDL/blood ; Female ; Humans ; Lipid Metabolism ; Lipoproteins/blood ; Pre-Eclampsia/blood ; Pre-Eclampsia/pathology ; Pregnancy ; Triglycerides/blood
    Chemical Substances Apolipoproteins B ; Cholesterol, LDL ; Lipoproteins ; Triglycerides ; lipoprotein cholesterol ; Cholesterol (97C5T2UQ7J)
    Language English
    Publishing date 2018-03-14
    Publishing country England
    Document type Clinical Trial ; Journal Article
    ZDB-ID 2091381-3
    ISSN 1476-511X ; 1476-511X
    ISSN (online) 1476-511X
    ISSN 1476-511X
    DOI 10.1186/s12944-018-0698-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cyclopentene ring effects in cyanine dyes: a handle to fine-tune photophysical properties.

    P Neme, Natália / Jansen, Thomas L C / Havenith, Remco W A

    Physical chemistry chemical physics : PCCP

    2024  Volume 26, Issue 7, Page(s) 6235–6241

    Abstract: The aim of this study is to investigate the photophysical properties of a cyanine dye analogue by performing first-principles calculations based on density functional theory (DFT) and time dependent-DFT. Cationic cyanine dyes are the subject of great ... ...

    Abstract The aim of this study is to investigate the photophysical properties of a cyanine dye analogue by performing first-principles calculations based on density functional theory (DFT) and time dependent-DFT. Cationic cyanine dyes are the subject of great importance due to their versatile applications and the tunability of their photophysical properties, such as by modifying their end groups and chain length. An example of this is the vinylene shift, which is experimentally known for these molecules, and it consists of a bathochromic (red) shift of approximately 100 nm of the 0-0 vibronic transition when a vinyl group is added to the polymethine chain. Our study shows that when the saturated moiety C
    Language English
    Publishing date 2024-02-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1476244-4
    ISSN 1463-9084 ; 1463-9076
    ISSN (online) 1463-9084
    ISSN 1463-9076
    DOI 10.1039/d3cp05219b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Echinochloa P. Beauvois (87-90); Eleusine coracana (L.) Gaertner cv. group Finger Millet (90-95); Panicum miliaceum L. cv. group Proso Millet (115-119); Setaria italica (L.) P. Beauvois cv. group Foxtail Millet (127-130); Minor cereals (150-156).

    Jansen, P.C.M.

    Cereals. Plant Resources of South-East Asia No 10

    1996  

    Keywords Life Science
    Language English
    Publisher Backhuys Publishers
    Publishing country nl
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The influence of the design of mental rotation trials on performance and possible differences between sexes: A theoretical review and experimental investigation.

    Jost, Leonardo / Jansen, Petra

    Quarterly journal of experimental psychology (2006)

    2023  , Page(s) 17470218231200127

    Abstract: Sex differences in mental rotation performance are one of the largest in cognitive psychology. Men outperform women by up to ... ...

    Abstract Sex differences in mental rotation performance are one of the largest in cognitive psychology. Men outperform women by up to 1
    Language English
    Publishing date 2023-10-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 219170-2
    ISSN 1747-0226 ; 0033-555X ; 1747-0218
    ISSN (online) 1747-0226
    ISSN 0033-555X ; 1747-0218
    DOI 10.1177/17470218231200127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1109: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Gender stereotypes in preschoolers' mental rotation.

    Ebert, W Miro / Jost, Leonardo / Jansen, Petra

    Frontiers in psychology

    2024  Volume 15, Page(s) 1284314

    Language English
    Publishing date 2024-02-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2024.1284314
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Synergistic interplay of UV radiation and urban particulate matter induces impairment of autophagy and alters cellular fate in senescence-prone human dermal fibroblasts.

    Guerrero-Navarro, Lena / Jansen-Dürr, Pidder / Cavinato, Maria

    Aging cell

    2024  Volume 23, Issue 4, Page(s) e14086

    Abstract: Skin aging is a complex process influenced by intrinsic factors and environmental stressors, including ultraviolet (UV) radiation and air pollution, among others. In this study, we investigated the effects of UVA and UVB radiation, combined with urban ... ...

    Abstract Skin aging is a complex process influenced by intrinsic factors and environmental stressors, including ultraviolet (UV) radiation and air pollution, among others. In this study, we investigated the effects of UVA and UVB radiation, combined with urban particulate matter (UPM), on human dermal fibroblasts (HDF). We show here that treatment of HDF with a subcytotoxic dose of UVA/UVB results in a series of events leading to mitochondrial dysfunction, increased ROS levels, and DNA damage. These effects are known to trigger either cellular senescence or cell death, depending on the cells' ability to clear damage by activating autophagy. Whereas UPM treatment in isolation did not affect proliferation or survival of HDF, of note, simultaneous UPM treatment of UV-irradiated cells selectively inhibited autophagic flux, thereby changing cell fate of a fraction of the cell population from senescence to apoptotic cell death. Our findings highlight the synergistic effects of UV radiation and UPM on skin aging, emphasizing the need to consider these factors in assessing the impact of environmental stressors on human health and opening opportunities for developing comprehensive approaches to protect and preserve skin integrity in the face of growing environmental challenges.
    MeSH term(s) Humans ; Ultraviolet Rays ; Cells, Cultured ; Skin/metabolism ; Cellular Senescence ; Skin Aging ; Fibroblasts/metabolism ; Autophagy
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2113083-8
    ISSN 1474-9726 ; 1474-9718
    ISSN (online) 1474-9726
    ISSN 1474-9718
    DOI 10.1111/acel.14086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6581: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  7. Article: Reciprocating subsurface-flow constructed wetlands: a microcosm treatability study.

    Behrends, Leslie / Houke, Laura / Bailey, Earl / Jansen, Pat

    Water science and technology : a journal of the International Association on Water Pollution Research

    2022  Volume 86, Issue 1, Page(s) 152–172

    Abstract: ... than 0.4 mg/L., while reciprocating treatments without P. arundinacea accumulated from 15-26 mg/L ... with P. arundinacea. Treatments with P. arundinacea had less accumulation of nitrate nitrogen; less ...

    Abstract Two batch-loaded microcosm treatability studies of eight days' duration (192 hours) were conducted concurrently from July 26 through August 3 in an environmentally controlled greenhouse at the Tennessee Valley Authority's (TVA) Constructed Wetlands Research Facility in Muscle Shoals, Alabama, USA. These, the first of five treatability studies, were conducted in batch-loaded wetland microcosms, with and without reciprocation. Reciprocation refers to the process of filling and draining paired wetland cells on a recurrent and timed basis to facilitate passive aeration of fixed microbial biofilms during the drain phase and oxygen depletion during the fill phase. The study was designed to simultaneously evaluate the influence of three treatment parameters with respect to removal dynamics of chemical oxygen demand (COD), total ammonia-nitrogen (TAN), nitrate-nitrogen, and orthophosphorus. The treatment parameters evaluated included four COD concentrations, two reciprocation cycle times, and the presence or absence of reed canary grass (Phalaris arundinacea), a plant with an anoxic rootzone. Temperature, pH, dissolved oxygen, electrical conductivity, redox potential, and evapotranspiration were also monitored. Results showed that treatments with reciprocation vs. no reciprocation provided significantly enhanced aerobic and anoxic treatment of wastewater and improved removal of COD and ammonium, irrespective of initial COD concentrations or planted vs. not planted with P. arundinacea. Treatments with P. arundinacea had less accumulation of nitrate nitrogen; less than 0.4 mg/L., while reciprocating treatments without P. arundinacea accumulated from 15-26 mg/L nitrate nitrogen over the 192-hour treatment period.
    MeSH term(s) Nitrates ; Nitrogen ; Organic Chemicals ; Oxygen ; Plants ; Waste Disposal, Fluid/methods ; Water Purification/methods ; Wetlands
    Chemical Substances Nitrates ; Organic Chemicals ; Nitrogen (N762921K75) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2022-07-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 764273-8
    ISSN 1996-9732 ; 0273-1223
    ISSN (online) 1996-9732
    ISSN 0273-1223
    DOI 10.2166/wst.2022.184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Einzelsignatur: Show issues

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  8. Article: SDHAF2

    de Jong, Monique A M / Corssmit, Eleonora P M / Jansen, Jeroen C / Potjer, Thomas P / Bayley, Jean-Pierre L / Hensen, Erik F

    Case reports in otolaryngology

    2024  Volume 2024, Page(s) 2111531

    Abstract: Head and neck paragangliomas are slow growing and highly vascular neuroendocrine tumors. It is currently assumed ... ...

    Abstract Head and neck paragangliomas are slow growing and highly vascular neuroendocrine tumors. It is currently assumed that
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2648756-1
    ISSN 2090-6773 ; 2090-6765
    ISSN (online) 2090-6773
    ISSN 2090-6765
    DOI 10.1155/2024/2111531
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Self-concept explains gender differences in mental rotation performance after stereotype activation.

    Rahe, Martina / Schürmann, Linda / Jansen, Petra

    Frontiers in psychology

    2023  Volume 14, Page(s) 1168267

    Language English
    Publishing date 2023-05-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2563826-9
    ISSN 1664-1078
    ISSN 1664-1078
    DOI 10.3389/fpsyg.2023.1168267
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Heartfulness in Vegans, Vegetarians, and Omnivores.

    Voll, Antonia / Jost, Leonardo / Jansen, Petra

    International journal of environmental research and public health

    2023  Volume 20, Issue 6

    Abstract: Background: The primary goal of this study was to investigate the relation between the choice of a vegan or vegetarian diet as a criterion of sustainability and the aspect of heartfulness. We also analyzed which demographic, diet-related, and ... ...

    Abstract Background: The primary goal of this study was to investigate the relation between the choice of a vegan or vegetarian diet as a criterion of sustainability and the aspect of heartfulness. We also analyzed which demographic, diet-related, and mindfulness practice-related variables could predict the different facets of heartfulness.
    Methods: In total, 419 persons participated. After providing demographic, diet-related, and mindfulness practice-related information, participants completed a gratitude questionnaire, a self-compassion scale, a compassion scale, and an equanimity scale.
    Results: The results show that vegans and vegetarians indicated higher scores than omnivores in some aspects of heartfulness, such as both self-compassion scales. These effects could not be shown for the two equanimity scales and for the gratitude questionnaire. Most aspects of heartfulness could either be predicted by demographic or diet-related variables. The best predictors of the elements of heartfulness were the ecological, ethical, or health-related reasons for choosing their diet stated by the participants, as well as the importance the participants attached to nutrition.
    Conclusion: This study provides evidence that vegans and vegetarians scored higher in several aspects of heartfulness. Vegans tended to score even higher than vegetarians. Both demographic and diet-related variables could predict heartfulness.
    MeSH term(s) Humans ; Vegans ; Vegetarians ; Diet, Vegan ; Diet, Vegetarian ; Diet
    Language English
    Publishing date 2023-03-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20064943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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