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  1. Article ; Online: Infection control in dental health care during and after the SARS-CoV-2 outbreak.

    Volgenant, Catherine M C / Persoon, Ilona F / de Ruijter, Rolf A G / de Soet, J J Hans

    Oral diseases

    2020  Volume 27 Suppl 3, Page(s) 674–683

    Abstract: COVID-19 is an emerging infectious disease caused by the widespread transmission of the coronavirus SARS-CoV-2. Some of those infected become seriously ill. Others do not show any symptoms, but can still contribute to transmission of the virus. SARS-CoV- ... ...

    Abstract COVID-19 is an emerging infectious disease caused by the widespread transmission of the coronavirus SARS-CoV-2. Some of those infected become seriously ill. Others do not show any symptoms, but can still contribute to transmission of the virus. SARS-CoV-2 is excreted in the oral cavity and can be spread via aerosols. Aerosol generating procedures in dental health care can increase the risk of transmission of the virus. Due to the risk of infection of both dental healthcare workers and patients, additional infection control measures for all patients are strongly recommended when providing dental health care. Consideration should be given to which infection control measures are necessary when providing care in both the current situation and in the future.
    MeSH term(s) COVID-19 ; Delivery of Health Care ; Dental Care ; Disease Outbreaks ; Health Personnel ; Humans ; Infection Control ; Infectious Disease Transmission, Patient-to-Professional/prevention & control ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-25
    Publishing country Denmark
    Document type Journal Article ; Review
    ZDB-ID 1290529-x
    ISSN 1601-0825 ; 1354-523X
    ISSN (online) 1601-0825
    ISSN 1354-523X
    DOI 10.1111/odi.13408
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Impact of the Coronavirus on Providing Oral Health Care in the Netherlands.

    Persoon, Ilona F / Volgenant, Catherine M C / van der Veen, Monique H / Opdam, Niek J M / Manton, David J / Bruers, Josef J M

    International dental journal

    2021  Volume 72, Issue 4, Page(s) 545–551

    Abstract: Objective: Transmission of SARS-CoV-2 during oral health care is potentially increased compared to regular social activities. Specific amendments to the Dutch national infection control guidelines were promulgated. This study aimed to map the impact of ... ...

    Abstract Objective: Transmission of SARS-CoV-2 during oral health care is potentially increased compared to regular social activities. Specific amendments to the Dutch national infection control guidelines were promulgated. This study aimed to map the impact of the coronavirus pandemic on providing oral health care during the first wave of the coronavirus pandemic in 2020 in the Netherlands.
    Methods: A cross-sectional web-based survey was sent via email to a representative sample of dental hygienists and dentists in the Netherlands.
    Results: Of the 1700 oral health care practitioners approached, 440 (25.9%) responded to the survey. Patient access to oral health care was severely restricted during the lockdown in the spring of 2020. A total of 1.6% of the oral health care practitioners had laboratory-confirmed COVID-19 during the study period, although this is likely to be an underrepresentation due to limited access to testing at that time. Over half of the participants perceived an increased risk of virus transmission during aerosol-generating treatments in their practices. A large majority (65.0%-87.1%) of the oral health care practitioners followed the COVID-19-specific amendments to the national infection control guidelines. Compared to the pre-pandemic period, additional personal protective equipment and protocols were applied. Factors related with compliance with the additional recommendations were age, employment status, and occupation.
    Conclusions: The pandemic had a profound impact on both the accessibility and practice of oral health care. This survey study found that most Dutch oral health care practitioners paid extra attention to hygiene and infection control. Also, a low number of COVID-19 infections detected amongst Dutch oral health care practitioners was reported in the Netherlands. These overall outcomes suggest that safe oral health care can be provided when following the current infection control recommendations.
    MeSH term(s) COVID-19/epidemiology ; COVID-19/prevention & control ; Cross-Sectional Studies ; Delivery of Health Care ; Dentists ; Humans ; Infection Control ; Netherlands/epidemiology ; SARS-CoV-2 ; Surveys and Questionnaires
    Language English
    Publishing date 2021-09-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 218262-2
    ISSN 1875-595X ; 0020-6539
    ISSN (online) 1875-595X
    ISSN 0020-6539
    DOI 10.1016/j.identj.2021.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A review of respiratory protection measures recommended in Europe for dental procedures during the COVID-19 pandemic

    Persoon, Ilona F. / Stankiewicz, Nikolai / Smith, Andrew / de Soet, Hans (J.J.) / Volgenant, Catherine M.C.

    2020  

    Abstract: No abstract available. ...

    Abstract No abstract available.
    Keywords covid19
    Language English
    Publisher Elsevier
    Publishing country uk
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Infection control in dental health care during and after the SARS‐CoV‐2 outbreak

    Volgenant, Catherine M. C. / Persoon, Ilona F. / Ruijter, Rolf A. G. / Soet, J. J. (Hans)

    Oral Diseases ; ISSN 1354-523X 1601-0825

    2020  

    Keywords Otorhinolaryngology ; General Dentistry ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/odi.13408
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Infection control in dental health care during and after the SARS-CoV-2 outbreak

    Volgenant, Catherine M C / Persoon, Ilona F / de Ruijter, Rolf A G / de Soet, J J Hans

    Oral dis

    Abstract: COVID-19 is an emerging infectious disease caused by the widespread transmission of the coronavirus SARS-CoV-2. Some of those infected become seriously ill. Others do not show any symptoms, but can still contribute to transmission of the virus. SARS-CoV- ... ...

    Abstract COVID-19 is an emerging infectious disease caused by the widespread transmission of the coronavirus SARS-CoV-2. Some of those infected become seriously ill. Others do not show any symptoms, but can still contribute to transmission of the virus. SARS-CoV-2 is excreted in the oral cavity and can be spread via aerosols. Aerosol generating procedures in dental health care can increase the risk of transmission of the virus. Due to the risk of infection of both dental healthcare workers and patients, additional infection control measures for all patients are strongly recommended when providing dental health care. Consideration should be given to which infection control measures are necessary when providing care in both the current situation and in the future.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #232609
    Database COVID19

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  6. Article ; Online: The mycobiome of root canal infections is correlated to the bacteriome.

    Persoon, Ilona F / Buijs, Mark J / Özok, Ahmet R / Crielaard, Wim / Krom, Bastiaan P / Zaura, Egija / Brandt, Bernd W

    Clinical oral investigations

    2017  Volume 21, Issue 5, Page(s) 1871–1881

    Abstract: Objectives: Bacterial infection of the root canal system causes apical periodontitis. Less is known about the role of fungi in these infections. This study aimed to assess the fungal prevalence, abundance, and diversity of root canal infections, as well ...

    Abstract Objectives: Bacterial infection of the root canal system causes apical periodontitis. Less is known about the role of fungi in these infections. This study aimed to assess the fungal prevalence, abundance, and diversity of root canal infections, as well as the relation between fungi and bacteria present in different parts of the root canal.
    Materials and methods: Twenty-six teeth with primary apical periodontitis were extracted, split in apical and coronal root segments, and cryo-pulverized. Bacteriome profiles of 23 teeth were analyzed based on the V3-V4 hypervariable region of the 16S ribosomal RNA gene. Mycobiome profiles of six teeth were analyzed based on the internal transcribed spacer (ITS) 1 or ITS2 region. Samples were sequenced on the Illumina MiSeq platform.
    Results: A total of 338 bacterial operational taxonomic units (OTUs), 28 ITS1 OTUs, and 24 ITS2 OTUs were identified. Candida and Malassezia were the most frequently identified fungi. No differences could be found between the bacteriome and mycobiome profiles of the apical and coronal root segments. The bacteriome of fungi-positive root segments contained more Actinomyces, Bifidobacterium, four different Lactobacillus OTUs, Propionibacterium, and Streptococcus. A Spearman correlation matrix between bacteriomes and mycobiomes identified no correlations, but separate clusters could be observed.
    Conclusions: A considerable proportion of the root canal infections contain fungi, although fungal diversity is limited. However, when fungi are present, the composition of the bacteriome is clearly different.
    Clinical relevance: Interaction between bacteria and fungi in root canal infections may complicate the infection and require alternative treatment strategies.
    Language English
    Publishing date 2017-06
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1364490-7
    ISSN 1436-3771 ; 1432-6981
    ISSN (online) 1436-3771
    ISSN 1432-6981
    DOI 10.1007/s00784-016-1980-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Antimicrobial effect of a modified vanadium chloroperoxidase on Enterococcus faecalis biofilms at root canal pH.

    Persoon, Ilona F / Hoogenkamp, Michel A / Bury, Aleksandra / Wesselink, Paul R / Hartog, Aloysius F / Wever, Ronald / Crielaard, Wim

    Journal of endodontics

    2013  Volume 39, Issue 8, Page(s) 1035–1038

    Abstract: Introduction: Previous research showed an antimicrobial effect of vanadium chloroperoxidase (VCPO) on in vitro Enterococcus faecalis biofilms. The current study aimed to optimize the use of this enzyme at the root canal pH using a modified VCPO (mVCPO) ... ...

    Abstract Introduction: Previous research showed an antimicrobial effect of vanadium chloroperoxidase (VCPO) on in vitro Enterococcus faecalis biofilms. The current study aimed to optimize the use of this enzyme at the root canal pH using a modified VCPO (mVCPO) that was adapted to function at a higher pH and to explore the biocompatibility of mVCPO.
    Methods: The activity of the original and modified VCPO was assessed using the monochlorodimedone assay. For antimicrobial assessment, 48-hour biofilms of E. faecalis OS-16 were incubated 5 or 30 minutes with mVCPO, bromide, and hydrogen peroxide, and colony-forming units were determined. A metabolic activity assay was used to evaluate the cytotoxic effect of mVCPO on oral fibroblasts.
    Results: Reaction products generated by mVCPO at a root canal pH of 7.7 significantly inactivated the biofilm after 5 minutes and even more after 30 minutes (Mann-Whitney U test, P < .05). The mVCPO reaction products showed less cytotoxic effects than control solutions and 0.5% sodium hypochlorite (Kruskal-Wallis test, P < .05).
    Conclusions: The incubation of mVCPO in the presence of its substrates with in vitro E. faecalis biofilms showed a significant antimicrobial effect at the root canal pH. Also, cytotoxicity tests showed preliminary biocompatibility. Therefore, an interappointment dressing containing mVCPO could aid in improving current endodontic treatment through continuous and local generation of antimicrobials.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/toxicity ; Biocompatible Materials/pharmacology ; Biocompatible Materials/toxicity ; Biofilms/drug effects ; Bromides/pharmacology ; Chloride Peroxidase/pharmacology ; Chloride Peroxidase/toxicity ; Cyclohexanones ; Dental Pulp Cavity/drug effects ; Dental Pulp Cavity/microbiology ; Enterococcus faecalis/drug effects ; Fibroblasts/drug effects ; Humans ; Hydrogen Peroxide/pharmacology ; Hydrogen-Ion Concentration ; Materials Testing ; Mouth Mucosa/cytology ; Mouth Mucosa/drug effects ; Oxidants/pharmacology ; Root Canal Irrigants/pharmacology ; Root Canal Irrigants/toxicity ; Sodium Hypochlorite/pharmacology ; Time Factors
    Chemical Substances Anti-Bacterial Agents ; Biocompatible Materials ; Bromides ; Cyclohexanones ; Oxidants ; Root Canal Irrigants ; chlorodimedone (7298-89-7) ; Hydrogen Peroxide (BBX060AN9V) ; Sodium Hypochlorite (DY38VHM5OD) ; vanadium chloroperoxidase (EC 1.11.1.-) ; Chloride Peroxidase (EC 1.11.1.10)
    Language English
    Publishing date 2013-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752412-2
    ISSN 1878-3554 ; 0099-2399
    ISSN (online) 1878-3554
    ISSN 0099-2399
    DOI 10.1016/j.joen.2013.04.038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effect of vanadium chloroperoxidase on Enterococcus faecalis biofilms.

    Persoon, Ilona F / Hoogenkamp, Michel A / Bury, Aleksandra / Wesselink, Paul R / Hartog, Aloysius F / Wever, Ronald / Crielaard, Wim

    Journal of endodontics

    2012  Volume 38, Issue 1, Page(s) 72–74

    Abstract: Introduction: The aim of this study was to explore the antimicrobial effect of vanadium chloroperoxidase (VCPO) reaction products on Enterococcus faecalis biofilms of 4 different strains.: Methods: Twenty-four-hour biofilms of E. faecalis strains ... ...

    Abstract Introduction: The aim of this study was to explore the antimicrobial effect of vanadium chloroperoxidase (VCPO) reaction products on Enterococcus faecalis biofilms of 4 different strains.
    Methods: Twenty-four-hour biofilms of E. faecalis strains V583, ER5/1, E2, and OS-16 were incubated in mixtures with VCPO, halide (either bromide or chloride), and hydrogen peroxide. The antibacterial efficacy was assessed by colony-forming unit counts.
    Results: The VCPO reaction products had a similar efficacy in reducing the viability of the 4 strains of E. faecalis (94%; range, 87%-100%). Bromide as the halogen of choice was more effective on E. faecalis strains E2 and OS-16, as compared with chloride (Mann-Whitney U test; P < .05). Despite different quantities of produced biofilms by the 4 strains, VCPO treatment was similarly effective toward all strains (Kruskal-Wallis test; P < .05).
    Conclusions: VCPO treatment results in an antimicrobial effect toward in vitro E. faecalis biofilms and might provide an addition to current endodontic treatment, possibly as an antimicrobial dressing.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Bacterial Load/drug effects ; Bacteriological Techniques ; Biofilms/drug effects ; Bromides/pharmacology ; Chloride Peroxidase/pharmacology ; Chlorides/pharmacology ; Enterococcus faecalis/classification ; Enterococcus faecalis/drug effects ; Humans ; Hydrogen Peroxide/pharmacology ; Microbial Viability/drug effects ; Sodium Hypochlorite/pharmacology
    Chemical Substances Anti-Bacterial Agents ; Bromides ; Chlorides ; Hydrogen Peroxide (BBX060AN9V) ; Sodium Hypochlorite (DY38VHM5OD) ; vanadium chloroperoxidase (EC 1.11.1.-) ; Chloride Peroxidase (EC 1.11.1.10)
    Language English
    Publishing date 2012-01
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 752412-2
    ISSN 1878-3554 ; 0099-2399
    ISSN (online) 1878-3554
    ISSN 0099-2399
    DOI 10.1016/j.joen.2011.09.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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