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  1. Article: The bivariate probit model, maximum likelihood estimation, pseudo true parameters and partial identification

    Li, Chuhui / D.S. Poskitt / Xueyan Zhao

    Journal of econometrics. 2019 Mar., v. 209, no. 1

    2019  

    Abstract: This paper examines the notion of “identification by functional form” for two equation triangular systems for binary endogenous variables by providing a bridge between the literature on the recursive bivariate probit model and that on partial ... ...

    Abstract This paper examines the notion of “identification by functional form” for two equation triangular systems for binary endogenous variables by providing a bridge between the literature on the recursive bivariate probit model and that on partial identification. We evaluate the impact of functional form on the performance of (quasi) maximum likelihood estimators, and investigate the practical importance of available instruments in both cases of correct and incorrect distributional specification. Finally, we calculate average treatment effect bounds and demonstrate how properties of the estimators are explicable via a link between the notion of pseudo-true parameters and the concepts of partial identification.
    Keywords econometric models ; economic analysis ; economic theory ; equations ; statistical analysis
    Language English
    Dates of publication 2019-03
    Size p. 94-113.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 1460617-3
    ISSN 0304-4076
    ISSN 0304-4076
    DOI 10.1016/j.jeconom.2018.07.009
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Complementary feeding and non communicable diseases: current knowledge and future research needs.

    Poskitt, E M E / Breda, J

    Nutrition, metabolism, and cardiovascular diseases : NMCD

    2012  Volume 22, Issue 10, Page(s) 819–822

    Abstract: ... b) how different body composition in infancy contributes to later NCDs, (c) whether there is an age ... window' when high protein intake is particularly associated with later overweight and obesity, (d ...

    Abstract Early diet and nutrition may set in place growth patterns and/or metabolic pathways that promote risk factors for later NCDs. Most relevant studies so far available have a cross-sectional or retrospective design and are thus of limited validity for evaluating the impact of early feeding on later disease. Standardised protocols for prospective research should be developed. The contribution of protein intake in early life to later NCD development has been the object of several studies; however future research should specifically target the effects of early protein intake on (a) how protein intake influences body composition, (b) how different body composition in infancy contributes to later NCDs, (c) whether there is an age 'window' when high protein intake is particularly associated with later overweight and obesity, (d) what levels of protein intake may protect against later overweight/obesity, (e) what level of cow milk intake in the first years of life minimises risk-inducing growth whilst meeting recommended calcium intakes. The role of the quality of fat and carbohydrate intakes at early ages should be better investigated. There is a dearth of data from many communities about the foods introduced as complementary feeds, the ages at which they are introduced and why mothers use these foods. Definitely more information is needed on how and to what extent mothers' behaviour is influenced by media, advertising and other commercial pressures and why formula fed infants are started on other foods much earlier than breast fed infants. Standardized protocols are needed to develop more data on complementary feeding in different regions, different countries and different socio-economic environments.
    MeSH term(s) Body Composition ; Breast Feeding/trends ; Chronic Disease/prevention & control ; Diet/trends ; Dietary Carbohydrates/administration & dosage ; Dietary Fats/administration & dosage ; Dietary Proteins/administration & dosage ; Energy Intake ; Feeding Behavior ; Humans ; Infant ; Infant Formula ; Infant Nutritional Physiological Phenomena ; Nutritional Status ; Obesity/physiopathology ; Obesity/prevention & control ; Overweight/physiopathology ; Overweight/prevention & control ; Risk Factors ; Sodium Chloride, Dietary/administration & dosage
    Chemical Substances Dietary Carbohydrates ; Dietary Fats ; Dietary Proteins ; Sodium Chloride, Dietary
    Language English
    Publishing date 2012-10
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1067704-5
    ISSN 1590-3729 ; 0939-4753
    ISSN (online) 1590-3729
    ISSN 0939-4753
    DOI 10.1016/j.numecd.2012.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Assessing the magnitude of the concentration parameter in a simultaneous equations model

    Poskitt, D. S / Skeels, C. L

    The econometrics journal Vol. 12, No. 1 , p. 26-44

    2009  Volume 12, Issue 1, Page(s) 26–44

    Author's details D. S. Poskitt and C. L. Skeels
    Language English
    Size graph. Darst.
    Publisher Wiley-Blackwell
    Publishing place Oxford [u.a.]
    Document type Article
    ZDB-ID 1412265-0 ; 1475536-1
    ISSN 1368-423X ; 1368-4221
    ISSN (online) 1368-423X
    ISSN 1368-4221
    Database ECONomics Information System

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  4. Article: Complementary feeding and non communicable diseases: Current knowledge and future research needs

    Poskitt, E.M.E / Breda, J

    Nutrition, metabolism and cardiovascular diseases. 2012 Oct., v. 22, no. 10

    2012  

    Abstract: ... b) how different body composition in infancy contributes to later NCDs, (c) whether there is an age ... window’ when high protein intake is particularly associated with later overweight and obesity, (d ...

    Abstract Early diet and nutrition may set in place growth patterns and/or metabolic pathways that promote risk factors for later NCDs. Most relevant studies so far available have a cross-sectional or retrospective design and are thus of limited validity for evaluating the impact of early feeding on later disease. Standardised protocols for prospective research should be developed. The contribution of protein intake in early life to later NCD development has been the object of several studies; however future research should specifically target the effects of early protein intake on (a) how protein intake influences body composition, (b) how different body composition in infancy contributes to later NCDs, (c) whether there is an age ‘window’ when high protein intake is particularly associated with later overweight and obesity, (d) what levels of protein intake may protect against later overweight/obesity, (e) what level of cow milk intake in the first years of life minimises risk-inducing growth whilst meeting recommended calcium intakes. The role of the quality of fat and carbohydrate intakes at early ages should be better investigated. There is a dearth of data from many communities about the foods introduced as complementary feeds, the ages at which they are introduced and why mothers use these foods. Definitely more information is needed on how and to what extent mothers' behaviour is influenced by media, advertising and other commercial pressures and why formula fed infants are started on other foods much earlier than breast fed infants. Standardized protocols are needed to develop more data on complementary feeding in different regions, different countries and different socio-economic environments.
    Keywords advertising ; biochemical pathways ; body composition ; breast feeding ; calcium ; infancy ; infant formulas ; infants ; infectious diseases ; milk ; milk consumption ; mothers ; obesity ; protein intake ; risk factors
    Language English
    Dates of publication 2012-10
    Size p. 819-822.
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 1067704-5
    ISSN 0939-4753
    ISSN 0939-4753
    DOI 10.1016/j.numecd.2012.08.005
    Database NAL-Catalogue (AGRICOLA)

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  5. Article: Conceptual frameworks and experimental design in simultaneous equations

    Poskitt, D. S / Skeels, C. L

    Economics letters Vol. 100, No. 1 , p. 138-142

    2008  Volume 100, Issue 1, Page(s) 138–142

    Author's details D. S. Poskitt; C. L. Skeels
    Keywords Test ; Simultanes Gleichungssystem
    Language English
    Size graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam [u.a.]
    Document type Article
    ZDB-ID 717210-2
    Database ECONomics Information System

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  6. Article ; Online: Neonatal Brain Injury and Timing of Neurodevelopmental Assessment in Patients With Congenital Heart Disease.

    Peyvandi, Shabnam / Chau, Vann / Guo, Ting / Xu, Duan / Glass, Hannah C / Synnes, Anne / Poskitt, Kenneth / Barkovich, A James / Miller, Steven P / McQuillen, Patrick S

    Journal of the American College of Cardiology

    2018  Volume 71, Issue 18, Page(s) 1986–1996

    Abstract: ... with single ventricle physiology (SVP) and d-transposition of the great arteries (d-TGA).: Methods: Term ... newborns with d-TGA and SVP had pre-operative and post-operative brain magnetic resonance imaging and ND ... minimal WMI for d-TGA and SVP (p = 0.03 and p = 0.05, respectively) after adjusting for various factors ...

    Abstract Background: Brain injury (BI) is reported in 60% of newborns with critical congenital heart disease as white matter injury (WMI) or stroke. Neurodevelopmental (ND) impairments are reported in these patients. The relationship between neonatal BI and ND outcome has not been established.
    Objectives: This study sought to determine the association between peri-operative BI and ND outcomes in infants with single ventricle physiology (SVP) and d-transposition of the great arteries (d-TGA).
    Methods: Term newborns with d-TGA and SVP had pre-operative and post-operative brain magnetic resonance imaging and ND outcomes assessed at 12 and 30 months with the Bayley Scales of Infant Development-II. BI was categorized by the brain injury severity score and WMI was quantified by volumetric analysis.
    Results: A total of 104 infants had follow-up at 12 months and 70 had follow-up at 30 months. At 12 months, only clinical variables were associated with ND outcome. At 30 months, subjects with moderate-to-severe WMI had significantly lower Psychomotor Development Index (PDI) scores (13 points lower) as compared with those with none or minimal WMI for d-TGA and SVP (p = 0.03 and p = 0.05, respectively) after adjusting for various factors. Quantitative WMI volume was likewise associated. Stroke was not associated with outcome. The Bland-Altman limits of agreement for PDI scores at 12 and 30 months were wide (-40.3 to 31.2) across the range of mean PDI values.
    Conclusions: Increasing burden of WMI is associated with worse motor outcomes at 30 months for infants with critical congenital heart disease, whereas no adverse association was seen between small strokes and outcome. These results support the utility of neonatal brain magnetic resonance imaging in this population to aid in predicting later outcomes and the importance of ND follow-up beyond 1 year of age.
    MeSH term(s) Brain Injuries/diagnostic imaging ; Brain Injuries/etiology ; Cardiac Surgical Procedures/adverse effects ; Female ; Humans ; Infant, Newborn ; Longitudinal Studies ; Male ; Neurodevelopmental Disorders/diagnostic imaging ; Neurodevelopmental Disorders/etiology ; Neuroimaging ; Perioperative Care ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/etiology ; Prospective Studies ; Transposition of Great Vessels/surgery
    Language English
    Publishing date 2018-05-03
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2018.02.068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Approximating the distribution of the two-stage least squares estimator when the concentration parameter is small

    Poskitt, D. S / Skeels, C. L

    Journal of econometrics Vol. 139, No. 1 , p. 217-236

    2007  Volume 139, Issue 1, Page(s) 217–236

    Author's details D. S. Poskitt; C. L. Skeels
    Keywords Schätztheorie ; Statistischer Test
    Language English
    Size graph. Darst.
    Publisher Elsevier
    Publishing place Amsterdam [u.a.]
    Document type Article
    ZDB-ID 184861-6
    Database ECONomics Information System

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  8. Article ; Online: Glutaric acidemia type 1: Treatment and outcome of 168 patients over three decades.

    Strauss, Kevin A / Williams, Katie B / Carson, Vincent J / Poskitt, Laura / Bowser, Lauren E / Young, Millie / Robinson, Donna L / Hendrickson, Christine / Beiler, Keturah / Taylor, Cora M / Haas-Givler, Barbara / Hailey, Jennifer / Chopko, Stephanie / Puffenberger, Erik G / Brigatti, Karlla W / Miller, Freeman / Morton, D Holmes

    Molecular genetics and metabolism

    2020  Volume 131, Issue 3, Page(s) 325–340

    Abstract: Glutaric acidemia type 1 (GA1) is a disorder of cerebral organic acid metabolism resulting from biallelic mutations of GCDH. Without treatment, GA1 causes striatal degeneration in >80% of affected children before two years of age. We analyzed clinical, ... ...

    Abstract Glutaric acidemia type 1 (GA1) is a disorder of cerebral organic acid metabolism resulting from biallelic mutations of GCDH. Without treatment, GA1 causes striatal degeneration in >80% of affected children before two years of age. We analyzed clinical, biochemical, and developmental outcomes for 168 genotypically diverse GA1 patients managed at a single center over 31 years, here separated into three treatment cohorts: children in Cohort I (n = 60; DOB 2006-2019) were identified by newborn screening (NBS) and treated prospectively using a standardized protocol that included a lysine-free, arginine-enriched metabolic formula, enteral l-carnitine (100 mg/kg•day), and emergency intravenous (IV) infusions of dextrose, saline, and l-carnitine during illnesses; children in Cohort II (n = 57; DOB 1989-2018) were identified by NBS and treated with natural protein restriction (1.0-1.3 g/kg•day) and emergency IV infusions; children in Cohort III (n = 51; DOB 1973-2016) did not receive NBS or special diet. The incidence of striatal degeneration in Cohorts I, II, and III was 7%, 47%, and 90%, respectively (p < .0001). No neurologic injuries occurred after 19 months of age. Among uninjured children followed prospectively from birth (Cohort I), measures of growth, nutritional sufficiency, motor development, and cognitive function were normal. Adherence to metabolic formula and l-carnitine supplementation in Cohort I declined to 12% and 32%, respectively, by age 7 years. Cessation of strict dietary therapy altered plasma amino acid and carnitine concentrations but resulted in no serious adverse outcomes. In conclusion, neonatal diagnosis of GA1 coupled to management with lysine-free, arginine-enriched metabolic formula and emergency IV infusions during the first two years of life is safe and effective, preventing more than 90% of striatal injuries while supporting normal growth and psychomotor development. The need for dietary interventions and emergency IV therapies beyond early childhood is uncertain.
    MeSH term(s) Amino Acid Metabolism, Inborn Errors/diet therapy ; Amino Acid Metabolism, Inborn Errors/epidemiology ; Amino Acid Metabolism, Inborn Errors/genetics ; Amino Acid Metabolism, Inborn Errors/metabolism ; Brain/metabolism ; Brain/pathology ; Brain Diseases, Metabolic/diet therapy ; Brain Diseases, Metabolic/epidemiology ; Brain Diseases, Metabolic/genetics ; Brain Diseases, Metabolic/metabolism ; Carnitine/metabolism ; Child ; Child, Preschool ; Corpus Striatum/metabolism ; Corpus Striatum/pathology ; Diet ; Female ; Glutaryl-CoA Dehydrogenase/deficiency ; Glutaryl-CoA Dehydrogenase/genetics ; Glutaryl-CoA Dehydrogenase/metabolism ; Humans ; Infant ; Infant, Newborn ; Lysine/metabolism ; Male
    Chemical Substances Glutaryl-CoA Dehydrogenase (EC 1.3.8.6) ; Lysine (K3Z4F929H6) ; Carnitine (S7UI8SM58A)
    Language English
    Publishing date 2020-10-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1418518-0
    ISSN 1096-7206 ; 1096-7192
    ISSN (online) 1096-7206
    ISSN 1096-7192
    DOI 10.1016/j.ymgme.2020.09.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Hippocampus, Amygdala, and Thalamus Volumes in Very Preterm Children at 8 Years: Neonatal Pain and Genetic Variation.

    Chau, Cecil M Y / Ranger, Manon / Bichin, Mark / Park, Min Tae M / Amaral, Robert S C / Chakravarty, Mallar / Poskitt, Kenneth / Synnes, Anne R / Miller, Steven P / Grunau, Ruth E

    Frontiers in behavioral neuroscience

    2019  Volume 13, Page(s) 51

    Abstract: ... preterm (<32 weeks GA) followed longitudinally from birth who underwent 3-D T1 MRI neuroimaging at ∼8 ...

    Abstract Altered hippocampal morphology and reduced volumes have been found in children born preterm compared to full-term. Stress inhibits neurogenesis in the hippocampus, and neonatal stress/noxious stimulation in rodent pups are associated with long-term alterations in hippocampal volumes. We have previously shown reduced cortical thickness and cerebellar volumes in relation to more exposure to pain-related stress of neonatal invasive procedures in children born very preterm. We have reported targeted gene-by-pain environment interactions that contribute to long-term brain development and outcomes in this population. We now aim to determine whether exposure to pain-related stress (adjusted for clinical factors and genotype) differentially impacts regional structures within the limbic system and thalamus, and investigate relationships with outcomes in very preterm children. Our study included 57 children born very preterm (<32 weeks GA) followed longitudinally from birth who underwent 3-D T1 MRI neuroimaging at ∼8 years. Hippocampal subfields and white matter tracts, thalamus and amygdala were automatically segmented using the MAGeT Brain algorithm. The relationship between those subcortical brain volumes (adjusted for total brain volume) and neonatal invasive procedures, gestational age (GA), illness severity, postnatal infection, days of mechanical ventilation, number of surgeries, morphine exposure, and genotype (
    Language English
    Publishing date 2019-03-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2452960-6
    ISSN 1662-5153
    ISSN 1662-5153
    DOI 10.3389/fnbeh.2019.00051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book: Small concentration asymptotics and instrumental variables inference

    Poskitt, D. S / Skeels, C. L

    (Working paper / Monash University, Department of Econometrics and Business Statistics ; 05,4)

    2005  

    Author's details D. S. Poskitt and C. L. Skeels
    Series title Working paper / Monash University, Department of Econometrics and Business Statistics ; 05,4
    Keywords Schätztheorie ; Mathematische Optimierung ; Inferenzstatistik
    Language English
    Size 19 S, graph. Darst
    Publishing place Clayton, Vic
    Document type Book
    Database ECONomics Information System

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