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  1. Article ; Online: A Brief Tutorial on Manuscript Preparation: From Journal Selection to Manuscript Review.

    Ochner, Christopher N / Mineo, Jocelyn

    HCA healthcare journal of medicine

    2020  Volume 1, Issue 1, Page(s) 3–10

    Abstract: Description This article is designed to introduce the novice researcher to the process of journal selection, manuscript submission and manuscript review. PubMed indexing, journal readership, scope, focus, impact factor, fees and acceptable manuscript ... ...

    Abstract Description This article is designed to introduce the novice researcher to the process of journal selection, manuscript submission and manuscript review. PubMed indexing, journal readership, scope, focus, impact factor, fees and acceptable manuscript types are discussed in the first section. The remainder of this article focuses on manuscript preparation, submission and review, including formatting, pre-submission inquiry, submission portals, and the manuscript review process. Specific recommendations are provided to assist the reader in navigating these stages.
    Language English
    Publishing date 2020-02-27
    Publishing country United States
    Document type Journal Article
    ISSN 2689-0216
    ISSN (online) 2689-0216
    DOI 10.36518/2689-0216.1023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Effects of Perioperative Peripheral Nerve Blocks on Peri- and Postoperative Opioid Use and Pain Management.

    Cardwell, Taylor W / Zabala, Vanessa / Mineo, Jocelyn / Ochner, Christopher N

    The American surgeon

    2021  Volume 88, Issue 12, Page(s) 2842–2850

    Abstract: Introduction: The amount of peri- and post-operative use of opioids for pain management, and the duration in which they are used following surgery, are positively associated with the likelihood of subsequent opioid use and addiction. Aware of this issue, ...

    Abstract Introduction: The amount of peri- and post-operative use of opioids for pain management, and the duration in which they are used following surgery, are positively associated with the likelihood of subsequent opioid use and addiction. Aware of this issue, many clinicians are seeking ways to reduce opioid use while maintaining adequate pain management. Recent evidence suggests that peripheral nerve block utilization may present a viable mechanism by which clinicians can accomplish this goal.
    Methods: Ovid MEDLINE and Pubmed databases were searched to identify relevant articles. Using the advanced search option, the key terms "opioid," "morphine," "nerve block," "peripheral anesthesia," "pain management," "preoperative,", "intraoperative," and "postoperative" were used and combined with the Boolean terms "AND" and "OR." This review examines the extant literature surrounding the use of peripheral nerve blocks in relation to patient-reported pain scores, intraoperative opioids, postoperative opioids, patient-controlled analgesic with opioids, and opioid consumption once the patient has left the hospital. Further, the effect peripheral nerve blocks have on postoperative physical therapy, surgery related complications, and overall patient satisfaction are briefly discussed.
    Results: The use of perioperative peripheral nerve blocks decreases opioid consumption not only in the postoperative period, but also intraoperatively as well. The most significant decrease in opioid consumption is seen in the first 24-72 hours postoperatively. Patient reported pain scores were also lower in patients who received peripheral nerve blocks.
    Discussion: Despite relatively robust efficacy data, utilization of peripheral nerve blocks is not ubiquitous; the potential reasons for which are also discussed. Lastly, clinical recommendations based on the available data are provided.
    MeSH term(s) Humans ; Pain Management ; Analgesics, Opioid/therapeutic use ; Pain, Postoperative/drug therapy ; Pain Measurement ; Peripheral Nerves ; Opioid-Related Disorders ; Postoperative Period
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2021-06-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348211023395
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cultivating a Resiliency Model for Emergency Department and Intensive Care Unit Staff Through Peer Support: A Program Description.

    Cipriano, Robert J / Shaver, Brenda / Sinyor, Benjamin / Jafri, Asma / Ochner, Christopher N / Van Hasselt, Vincent

    Advanced emergency nursing journal

    2022  Volume 44, Issue 3, Page(s) 242–247

    Abstract: Emergency department (ED) and intensive care unit (ICU) staff experience significant and ongoing exposure to mental health trauma due to the extremely high number of tragic cases consistently seen. Despite awareness of the magnitude of this problem, ... ...

    Abstract Emergency department (ED) and intensive care unit (ICU) staff experience significant and ongoing exposure to mental health trauma due to the extremely high number of tragic cases consistently seen. Despite awareness of the magnitude of this problem, there is a scarcity of clinical efforts directed toward reducing and managing secondary traumatic stress and vicarious trauma. In an effort to promote resiliency in these frontline workers, we describe development and implementation of the Adapted Peer Support Resiliency Program (APSRP), a psychoeducational and cognitive reframing behavioral-based program equipped with peer support professionals who are trained in cognitive-behavioral strategies specifically tailored toward the needs of this population. The APSRP is an adaption of concepts and coping skills utilized by the Penn Resilience Program, which has previously demonstrated efficacy in combating a range of psychological problems (e.g., anxiety, depression, substance abuse, eating disorders, and severe mental illness). The APSRP incorporates a range of cognitive-behavioral strategies inclusive of cognitive reframing skills, role-playing, and behavior rehearsal. This proposed program was facilitated and supervised by a licensed mental health professional and implemented by fellow ED and ICU peer professionals. Components of the APSRP model are discussed. Suggestions for directing future efforts within this needed area are offered.
    MeSH term(s) Adaptation, Psychological ; Anxiety ; Emergency Service, Hospital ; Humans ; Intensive Care Units ; Program Development
    Language English
    Publishing date 2022-07-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2257871-7
    ISSN 1931-4493 ; 1931-4485
    ISSN (online) 1931-4493
    ISSN 1931-4485
    DOI 10.1097/TME.0000000000000420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Negative Troponin I as a Predictor of Survival in Patients With Coronavirus Disease 2019.

    Losiniecki, Fergie J / Lopez, Jose / Jazaerly, Majd / Menchaca, Kristina / Kothari, Vivek / Cornett, Brendon / Ochner, Christopher N / Chait, Robert

    International journal of cardiology. Heart & vasculature

    2023  Volume 45, Page(s) 101196

    Abstract: Background: Despite a large amount of evidence evaluating elevated troponin I levels and adverse clinical outcomes, little is known about the role of a normal (negative) troponin I during the first 24 h of admission for risk stratification in patients ... ...

    Abstract Background: Despite a large amount of evidence evaluating elevated troponin I levels and adverse clinical outcomes, little is known about the role of a normal (negative) troponin I during the first 24 h of admission for risk stratification in patients with Coronavirus Disease 2019 (COVID-19). This study aims to evaluate the utility and negative predictive value of a serum troponin I level to predict in-hospital mortality.
    Methods: We retrospectively analyzed all adult patients (>18 years of age) with COVID-19 admitted to an HCA Healthcare facility between March 2020 and March 2021 who had a troponin I level drawn at admission. Patients were initially stratified into two groups based on their cardiac troponin I value in the first 24 h of admission (elevated vs negative).
    Results: A total of 65,580 patients were included in the final analysis. A negative troponin I value was associated with lesser odds of death during admission (OR = 0.32, 95 % CI 0.31-0.34, p < 0.01) and cardiac complications (OR = 0.38, 95 % CI 0.37-0.40, p < 0.01). The negative predictive value of a negative troponin value for all-cause in-hospital mortality was 85.7 %.
    Conclusions: Our study found a significant association between a negative troponin I value in the first 24 h of admission and decreased odds of death during admission in patients with confirmed COVID-19 infection, in addition to decreased odds of cardiac complications but no significant difference in hospital length of stay. Therefore, the authors suggest that the absence of troponin I elevation may serve as an indicator of a more benign hospital course.
    Language English
    Publishing date 2023-03-16
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 2818464-6
    ISSN 2352-9067
    ISSN 2352-9067
    DOI 10.1016/j.ijcha.2023.101196
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Neurobiological evidence for attention bias to food, emotional dysregulation, disinhibition and deficient somatosensory awareness in obesity with binge eating disorder.

    Aviram-Friedman, Roni / Astbury, Nerys / Ochner, Christopher N / Contento, Isobel / Geliebter, Allan

    Physiology & behavior

    2018  Volume 184, Page(s) 122–128

    Abstract: ... LEUF), or non-foods (NF) in 42 adults (obese with BED [obese -BED; n=13] and obese with no BED [obese ... non-BED; n=29]) selected via ads. Two blood oxygenated level dependent (BOLD) signal contrast maps ...

    Abstract Objectives: To refine the biobehavioral markers of binge eating disorder (BED).
    Methods: We conducted fMRI brain scans using images of high energy processed food (HEPF), low energy unprocessed food (LEUF), or non-foods (NF) in 42 adults (obese with BED [obese -BED; n=13] and obese with no BED [obese non-BED; n=29]) selected via ads. Two blood oxygenated level dependent (BOLD) signal contrast maps were examined: food versus nonfood, and HEPF versus LEUF. In addition, score differences on the disinhibition scale were correlated with BOLD signals.
    Results: food versus nonfood showed greater BOLD activity for BED in emotional, motivational and somatosensory brain areas: insula, anterior cingulate cortex (ACC), Brodmann areas (BA) 19 & 32, inferior parietal lobule (IPL), posterior cingulate cortex (PCC), and lingual, postcentral, middle temporal and cuneate gyri (p≤0.005; k≥88). HEPF versus LEUF showed greater BOLD activity for BED in inhibitory brain regions: BA 6, middle and superior frontal gyri (p<0.01; k≥119). The groups also differed in the relationships between disinhibition and BOLD activity in the postcentral gyrus (PCG; p=0.04) and ACC-BA 32 (p=0.02). For all participants jointly, PCG BOLD amplitude predicted greater disinhibition (p=0.04).
    Discussion: Food images elicited neural activity indicating attention bias (cuneate & PCG), emotion dysregulation (BA 19 & 32), and disinhibition (MFG, BA6 & SFG) in obese with BED. These may help tailor a treatment for the obesity with BED phenotype.
    MeSH term(s) Adolescent ; Adult ; Affective Symptoms/diagnostic imaging ; Affective Symptoms/etiology ; Aged ; Attention/physiology ; Awareness/physiology ; Binge-Eating Disorder/complications ; Binge-Eating Disorder/pathology ; Binge-Eating Disorder/psychology ; Brain/diagnostic imaging ; Female ; Food ; Functional Laterality ; Humans ; Image Processing, Computer-Assisted ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Obesity/complications ; Obesity/pathology ; Oxygen/blood ; Psychiatric Status Rating Scales ; Somatosensory Disorders/diagnostic imaging ; Somatosensory Disorders/etiology ; Somatosensory Disorders/psychology ; Young Adult
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2018--01
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 3907-x
    ISSN 1873-507X ; 0031-9384
    ISSN (online) 1873-507X
    ISSN 0031-9384
    DOI 10.1016/j.physbeh.2017.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Reversible biological adaptations in obesity - Authors' reply.

    Ochner, Christopher N / Tsai, Adam G / Kushner, Robert F / Wadden, Thomas A

    The lancet. Diabetes & endocrinology

    2015  Volume 3, Issue 5, Page(s) 314–315

    MeSH term(s) Adaptation, Physiological/physiology ; Caloric Restriction ; Humans ; Life Style ; Obesity/therapy
    Language English
    Publishing date 2015-05
    Publishing country England
    Document type Comment ; Letter
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(15)00091-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Treating obesity seriously: when recommendations for lifestyle change confront biological adaptations.

    Ochner, Christopher N / Tsai, Adam G / Kushner, Robert F / Wadden, Thomas A

    The lancet. Diabetes & endocrinology

    2015  Volume 3, Issue 4, Page(s) 232–234

    MeSH term(s) Adaptation, Physiological/physiology ; Adipocytes/physiology ; Caloric Restriction ; Cell Proliferation/physiology ; Dopamine/physiology ; Habituation, Psychophysiologic/physiology ; Humans ; Life Style ; Obesity/therapy ; Signal Transduction ; Treatment Failure
    Chemical Substances Dopamine (VTD58H1Z2X)
    Language English
    Publishing date 2015-04
    Publishing country England
    Document type Journal Article
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(15)00009-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The Body Shape Questionnaire Is Not Invariant Across Sex: Evidence From Portuguese-Speaking University Students.

    da Silva, Wanderson Roberto / Swami, Viren / Nogueira Neves, Angela / Marôco, João / Ochner, Christopher N / Alvares Duarte Bonini Campos, Juliana

    Perceptual and motor skills

    2019  Volume 126, Issue 3, Page(s) 462–476

    Abstract: ... To determine the extent to which BSQ scores are sex invariant, we asked Portuguese-speaking women ( n = 1,613 ... and men ( n = 871) to complete the full BSQ (34 items). Confirmatory factor analysis indicated ...

    Abstract The Body Shape Questionnaire (BSQ) is a widely used measure of body shape concerns that was originally designed for use with women but has more recently been used with boys and men. The latter use may be problematic, given that no previous study has demonstrated sex invariance for BSQ scores. To determine the extent to which BSQ scores are sex invariant, we asked Portuguese-speaking women ( n = 1,613) and men ( n = 871) to complete the full BSQ (34 items). Confirmatory factor analysis indicated that a hypothesized 32-item model of BSQ scores and shorter versions had acceptable fit indices in women and men, separately. However, multigroup confirmatory factor analysis showed that these BSQ model scores had configural but not metric, scalar, or strict sex invariance. Differential item analysis indicated significant item-functioning differences on 19 of the 32 retained BSQ items. Thus, BSQ scores are not sex invariant, making problematic the results of previous studies that have compared latent BSQ scores across sex.
    MeSH term(s) Adult ; Body Image ; Brazil ; Female ; Humans ; Male ; Portugal ; Psychometrics/instrumentation ; Psychometrics/standards ; Reproducibility of Results ; Sex Factors ; Surveys and Questionnaires/standards ; Young Adult
    Language English
    Publishing date 2019-03-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 204507-2
    ISSN 1558-688X ; 0031-5125
    ISSN (online) 1558-688X
    ISSN 0031-5125
    DOI 10.1177/0031512519839537
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Male body dissatisfaction scale (MBDS): proposal for a reduced model.

    da Silva, Wanderson Roberto / Marôco, João / Ochner, Christopher N / Campos, Juliana Alvares Duarte Bonini

    Eating and weight disorders : EWD

    2017  Volume 22, Issue 3, Page(s) 515–525

    Abstract: Aims: To evaluate the psychometric properties of the male body dissatisfaction scale (MBDS) in Brazilian and Portuguese university students; to present a reduced model of the scale; to compare two methods of computing global scores for participants' ... ...

    Abstract Aims: To evaluate the psychometric properties of the male body dissatisfaction scale (MBDS) in Brazilian and Portuguese university students; to present a reduced model of the scale; to compare two methods of computing global scores for participants' body dissatisfaction; and to estimate the prevalence of participants' body dissatisfaction.
    Methods: A total of 932 male students participated in this study. A confirmatory factor analysis (CFA) was used to assess the scale's psychometric properties. Multi-group analysis was used to test transnational invariance and invariance in independent samples. The body dissatisfaction score was calculated using two methods (mean and matrix of weights in the CFA), which were compared. Finally, individuals were classified according to level of body dissatisfaction, using the best method.
    Results: The MBDS model did not show adequate fit for the sample and was, therefore, refined. Thirteen items were excluded and two factors were combined. A reduced model of 12 items and 2 factors was proposed and shown to have adequate psychometric properties. There was a significant difference (p < 0.001) between the methods for calculating the score for body dissatisfaction, since the mean overestimated the scores. Among student participants, the prevalence of body dissatisfaction with musculature and general appearance was 11.2 and 5.3%, respectively.
    Conclusions: The reduced bi-factorial model of the MBDS showed adequate validity, reliability, and transnational invariance and invariance in independent samples for Brazilian and Portuguese students. The new proposal for calculating the global score was able to more accurately show their body dissatisfaction. No level of evidence Basic Science.
    MeSH term(s) Adolescent ; Adult ; Body Image/psychology ; Brazil ; Cross-Sectional Studies ; Humans ; Male ; Men/psychology ; Models, Psychological ; Personal Satisfaction ; Portugal ; Psychometrics ; Reproducibility of Results ; Young Adult
    Language English
    Publishing date 2017-08-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2038625-4
    ISSN 1590-1262 ; 1124-4909
    ISSN (online) 1590-1262
    ISSN 1124-4909
    DOI 10.1007/s40519-017-0420-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Obesity-Related Hormones and Metabolic Risk Factors: A Randomized Trial of Diet plus Either Strength or Aerobic Training versus Diet Alone in Overweight Participants.

    Geliebter, Allan / Ochner, Christopher N / Dambkowski, Carl L / Hashim, Sami A

    Journal of diabetes and obesity

    2014  Volume 1, Issue 1, Page(s) 1–7

    Abstract: There is debate about the additive effects of exercise in conjunction with diet to treat obesity, and not much is known about the differential effects of strength versus aerobic training. This randomized controlled trial examined the effects of diet plus ...

    Abstract There is debate about the additive effects of exercise in conjunction with diet to treat obesity, and not much is known about the differential effects of strength versus aerobic training. This randomized controlled trial examined the effects of diet plus strength training, diet plus aerobic training, or diet only on metabolic risk factors associated with obesity. Eighty-one overweight and obese participants completed the 8-week intervention. All participants received an energy-restrictive formula diet with an energy content based on 70% of measured resting metabolic rate (RMR). Participants assigned to an exercise group trained 3 days/week under supervision. Anthropometrics and fasting hormones were assessed pre- and post-intervention. Mean weight loss (8.5 ± 4.3kg SD) did not differ between groups nor did reductions in BMI or body fat, although the diet plus strength training group showed marginally greater lean mass retention. There were significant improvements in the values and number of metabolic syndrome risk factors, and decreases in insulin concentrations and insulin resistance, which did not vary between groups. For men, testosterone increased significantly more in the diet plus aerobic training as compared to the other groups. As compared to diet alone, the addition of strength or aerobic training did not improve changes in BMI, body fat or metabolic risk factors although the diet plus strength training group showed a trend toward preservation of lean mass, and the diet plus aerobic group in men resulted in increased testosterone concentrations.
    Language English
    Publishing date 2014-12-30
    Publishing country United States
    Document type Journal Article
    ISSN 2376-0494
    ISSN 2376-0494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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