LIVIVO - Search results -

Search results

Result 1 - 10 of total 23

Search options

Article: Silent witnesses: the experience of having a sibling with anorexia nervosa.

Hutchison, Suzanne / House, Jennifer / McDermott, Beth / Simic, Mima / Baudinet, Julian / Eisler, Ivan

2022 Volume 10, Issue 1, Page(s) 134

Abstract: Background: This study explored the experience of having a sibling with anorexia nervosa and the sibling perspectives on service provision.: Method: Four focus groups were conducted with 14 siblings (8 female, 6 male, age 11-19 years) of adolescents ... ...

Abstract	Background: This study explored the experience of having a sibling with anorexia nervosa and the sibling perspectives on service provision. Method: Four focus groups were conducted with 14 siblings (8 female, 6 male, age 11-19 years) of adolescents with anorexia nervosa or related restrictive eating disorders. Group discussions were transcribed and analysed using thematic analysis. Results: Four themes and eight sub-themes were generated. These illustrated siblings feel greatly affected by the way the family needs to change to support someone with anorexia nervosa. Feelings of ambivalence and acceptance were also evident. They described silencing their own emotions and needs so as not to trouble others, and distancing themselves from their families in order to cope. Some female (but no male) siblings identified an impact on their own perceptions of eating and body image. Siblings generally felt that services had not attended to their needs, and that they had not been appropriately included in treatment. Conclusions: Data from this study suggest the sibling experience needs to be more carefully considered and included in treatment. This may include a more explicit invitation to sessions and a more active discussion about their own needs and useful involvement in treatment sessions. Findings point to ways siblings may be better supported, such as peer support groups.
Language	English
Publishing date	2022-09-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2699357-0
ISSN	2050-2974
ISSN	2050-2974
DOI	10.1186/s40337-022-00655-1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: CaMKII-delta isoform regulation of neointima formation after vascular injury.

House, Suzanne J / Singer, Harold A

Arteriosclerosis, thrombosis, and vascular biology

2007 Volume 28, Issue 3, Page(s) 441–447

Abstract: Objective: The purpose of this study was to test the function of the calcium/calmodulin-dependent protein kinase II delta2 isoform (CaMKIIdelta2) in regulating vascular smooth muscle (VSM) cell proliferation and migration in response to vascular injury.! ...

Abstract	Objective: The purpose of this study was to test the function of the calcium/calmodulin-dependent protein kinase II delta2 isoform (CaMKIIdelta2) in regulating vascular smooth muscle (VSM) cell proliferation and migration in response to vascular injury. Methods and results: CaMKII isoform content was assessed in rat carotid arteries after balloon angioplasty-induced injury by Western blotting with isoform specific antibodies. Within 3 days after injury, a significant increase in CaMKIIdelta2 and decrease in CaMKIIgamma isoform content was observed in both medial smooth muscle and adventitial fibroblasts. Neointimal VSM cells expressed primarily the delta2 isoform. Incubation of the injured vessel with adenovirus encoding siRNA targeting CaMKIIdelta isoforms prevented upregulation of the delta2 isoform in the media and adventitia; inhibited cell proliferation assessed by PCNA expression in both layers and markedly inhibited neointima formation and adventitial thickening. Conclusions: CaMKIIdelta2 is specifically induced in VSM and adventitial fibroblasts during the response of an artery to injury and is a positive regulator of proliferation and migration in the vessel wall contributing to neointima formation and vascular remodeling. This provides a potential mechanism for Ca2+-dependent regulation of VSM and myofibroblast proliferation and migration in response to vascular injury or disease.
MeSH term(s)	Adenoviridae ; Angioplasty, Balloon ; Animals ; Biomarkers/metabolism ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Carotid Artery Injuries/enzymology ; Carotid Artery Injuries/pathology ; Cell Movement/physiology ; Cell Proliferation ; Cells, Cultured ; Disease Models, Animal ; Gene Expression Regulation, Enzymologic ; Immunohistochemistry ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Male ; Muscle, Smooth, Vascular/cytology ; Muscle, Smooth, Vascular/metabolism ; Myocytes, Smooth Muscle/cytology ; Myocytes, Smooth Muscle/enzymology ; Neovascularization, Physiologic/genetics ; Neovascularization, Physiologic/physiology ; Rats ; Rats, Sprague-Dawley ; Sensitivity and Specificity ; Tunica Intima/enzymology ; Tunica Intima/pathology ; Up-Regulation
Chemical Substances	Biomarkers ; Isoenzymes ; Calcium-Calmodulin-Dependent Protein Kinase Type 2 (EC 2.7.11.17)
Language	English
Publishing date	2007-12-20
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1221433-4
ISSN	1524-4636 ; 1079-5642
ISSN (online)	1524-4636
ISSN	1079-5642
DOI	10.1161/ATVBAHA.107.156810
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1705: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Pediatric and neonatal intubation training gap analysis: instruction, assessment, and technology.

Klotz, Jessica J / Dooley-Hash, Suzanne L / House, Joseph B / Andreatta, Pamela B

Simulation in healthcare : journal of the Society for Simulation in Healthcare

2014 Volume 9, Issue 6, Page(s) 377–383

Abstract: Summary statement: Intubating adult patients presents numerous challenges for clinicians. Procedural complexities associated with performing pediatric and neonatal intubation, along with a lower frequency of a need for intubating pediatric and neonatal ... ...

Abstract	Summary statement: Intubating adult patients presents numerous challenges for clinicians. Procedural complexities associated with performing pediatric and neonatal intubation, along with a lower frequency of a need for intubating pediatric and neonatal patients, further amplifies the difficulties associated with acquiring and maintaining relevant clinical skills. Clinicians must develop and maintain competency through training and continuing medical education. A systematic review was conducted through June 2012 to examine current instructional methods, assessment tools, and training models in pediatric and neonatal intubation training. Variability among the included literature on instruction, assessment, and models used to support training makes direct comparison problematic. The results of this review emphasize the need for improvement of current instructional methods to promote competency acquisition; development of valid, reliable assessment tools to evaluate clinician competency; and identification of a superior training model to promote acquisition and maintenance of skills associated with intubation of pediatric patients.
MeSH term(s)	Child, Preschool ; Humans ; Infant ; Infant, Newborn ; Inservice Training/standards ; Intubation/instrumentation ; Intubation/standards ; Teaching
Language	English
Publishing date	2014-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2223429-9
ISSN	1559-713X ; 1559-2332
ISSN (online)	1559-713X
ISSN	1559-2332
DOI	10.1097/SIH.0000000000000057
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: An intervention to support stroke survivors and their carers in the longer term: results of a cluster randomised controlled feasibility trial (LoTS2Care).

Forster, Anne / Ozer, Seline / Brindle, Richard / Barnard, Lorna / Hardicre, Natasha / Crocker, Thomas F / Chenery, Marie / Moreau, Lauren / Wright, Alan / Burton, Louisa-Jane / Hartley, Suzanne / Hulme, Claire / Dawkins, Bryony / Holloway, Ivana / House, Allan / Hewison, Jenny / Farrin, Amanda

Pilot and feasibility studies

2023 Volume 9, Issue 1, Page(s) 40

Abstract: Background: To address the limited provision of longer-term stroke care, we conducted a programme of research (LoTS2Care) to develop and test an intervention to form part of a replicable longer-term care strategy. New Start, a programme of facilitated ... ...

Abstract	Background: To address the limited provision of longer-term stroke care, we conducted a programme of research (LoTS2Care) to develop and test an intervention to form part of a replicable longer-term care strategy. New Start, a programme of facilitated self-management, was developed to be delivered at 6 months post-stroke by trained facilitators. Here, we report the findings from the final workstream of this programme, which aimed to evaluate the feasibility and acceptability of implementing a future definitive cluster randomised controlled trial of the developed intervention (New Start) to support stroke survivors and their carers in the longer term. Methods: A feasibility cluster randomised controlled trial was conducted in English and Welsh NHS stroke services. Stroke services (clusters) were randomised on a 1:1 basis to implement New Start or continue with usual care only. Community-dwelling stroke survivors between 4 and 6 months post-stroke were invited to participate in the trial by post. Outcome measures were collected via post at 3, 6 and 9 months after recruitment. Recruitment and follow-up rates, delivery and uptake of the intervention, data collection feasibility (including postal outcome measures of health and disability, mental well-being at 3, 6, and 9 months post-recruitment) and safety were assessed. Results: Ten stroke services were recruited. A total of 1127 stroke survivors were screened for participation, and 269 were registered (New Start, n = 145; usual care, n = 124). Retention was high with 239 (89%) stroke survivors being available for follow-up at 9 months, and high return rates of postal questionnaires were achieved (80.3% at 9 months). Intervention training was successfully delivered, and New Start was offered to 95.2% of trial participants in the intervention arm. Uptake was variable, however, ranging from 11.8 to 75.0%. There were no safety concerns. Conclusions: Stroke service recruitment and longer-term stroke survivor postal recruitment and outcome data collection are feasible; however, refinement of intervention targeting and delivery is required prior to undertaking a definitive trial. Trial registration: ISRCTN38920246. Registered 22 June 2016 ( http://www.isrctn.com/ISRCTN38920246 ).
Language	English
Publishing date	2023-03-15
Publishing country	England
Document type	Journal Article
ZDB-ID	2809935-7
ISSN	2055-5784
ISSN	2055-5784
DOI	10.1186/s40814-023-01258-6
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Effects of rhinovirus 39 infection on airway hyperresponsiveness to carbachol in human airways precision cut lung slices.

Kennedy, Joshua L / Koziol-White, Cynthia J / Jeffus, Susanne / Rettiganti, Mallikarjuna R / Fisher, Paige / Kurten, Megan / Eze, Anthony / House, Suzanne / Sikes, James D / Askew, Emily / Putt, Claire / Panettieri, Reynold A / Jones, Stacie M / Kurten, Richard C

The Journal of allergy and clinical immunology

2018 Volume 141, Issue 5, Page(s) 1887–1890.e1

MeSH term(s)	Adult ; Carbachol/immunology ; Female ; Humans ; Lung/immunology ; Lung/virology ; Male ; Picornaviridae Infections/immunology ; Picornaviridae Infections/virology ; Respiratory Hypersensitivity/immunology ; Respiratory Hypersensitivity/virology ; Rhinovirus/immunology ; Young Adult
Chemical Substances	Carbachol (8Y164V895Y)
Language	English
Publishing date	2018-01-06
Publishing country	United States
Document type	Letter ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	121011-7
ISSN	1097-6825 ; 1085-8725 ; 0091-6749
ISSN (online)	1097-6825 ; 1085-8725
ISSN	0091-6749
DOI	10.1016/j.jaci.2017.11.041
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Uh III Zs.92: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Retention Curves for Pediatric and Neonatal Intubation Skills After Simulation-Based Training.

Andreatta, Pamela B / Dooley-Hash, Suzanne L / Klotz, Jessica J / Hauptman, Joe G / Biddinger, Bea / House, Joseph B

Pediatric emergency care

2016 Volume 32, Issue 2, Page(s) 71–76

Abstract: Objectives: We evaluated the retention of pediatric and neonatal intubation performance abilities of clinicians trained on a simulated or live tissue model at 3 intervals after initial training to assess competency degradation related to either training ...

Abstract	Objectives: We evaluated the retention of pediatric and neonatal intubation performance abilities of clinicians trained on a simulated or live tissue model at 3 intervals after initial training to assess competency degradation related to either training modality or retention interval. Methods: We implemented a quasi-experimental design with purposive sampling to assess performance differences between 171 subjects randomly assigned to 1 of 3 intervals after initial training: 6 weeks, 18 weeks, or 52 weeks. Training followed the American Heart Association Pediatric Advanced Life Support and Neonatal Resuscitation Program protocols with hands-on practice using 1 of 2 models (live feline or simulated feline). Assessment data were captured using validated instruments and analyzed using analysis of variance with repeated measures (statistical significance set at P < 0.05). Results: Cognitive retention scores decreased significantly (P = 0.000) from posttraining cognitive scores. There were no significant differences between posttraining and retention scores for pediatric and neonatal performances. Both affect and self-efficacy retention scores decreased significantly (P = 0.000) from posttraining scores at 18 and 52 weeks, but remained constant at 6 weeks. Retention scores for all dimensions showed a significant difference between subjects with varying amounts of experience performing pediatric and neonatal intubation, such that those with more experience scored higher those with less (P < 0.003). Conclusions: Retention performance outcomes decreased sufficiently from posttraining scores to suggest that training refreshment could serve to maintain posttraining competency in the ability to perform pediatric and neonatal intubation. Retraining intervals may be best aligned with provider experience levels. Future research focusing on the effect of variable interval refresher training on retention in pediatric and neonatal intubation is merited.
MeSH term(s)	Animals ; Cats ; Child ; Clinical Competence ; Computer Simulation ; Educational Measurement/methods ; Humans ; Infant, Newborn ; Intubation, Intratracheal/methods ; Manikins ; Non-Randomized Controlled Trials as Topic ; Pediatrics/education ; Time Factors ; United States
Language	English
Publishing date	2016-02
Publishing country	United States
Document type	Journal Article
ZDB-ID	632588-9
ISSN	1535-1815 ; 0749-5161
ISSN (online)	1535-1815
ISSN	0749-5161
DOI	10.1097/PEC.0000000000000603
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2083: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Metabolism of megestrol acetate in vitro and the role of oxidative metabolites.

House, Larry / Seminerio, Michael J / Mirkov, Snezana / Ramirez, Jacqueline / Skor, Maxwell / Sachleben, Joseph R / Isikbay, Masis / Singhal, Hari / Greene, Geoffrey L / Vander Griend, Donald / Conzen, Suzanne D / Ratain, Mark J

Xenobiotica; the fate of foreign compounds in biological systems

2017 Volume 48, Issue 10, Page(s) 973–983

Abstract: 1. There is limited knowledge regarding the metabolism of megestrol acetate (MA), as it was approved by FDA in 1971, prior to the availability of modern tools for identifying specific drug-metabolizing enzymes. We determined the cytochrome P450s (P450s) ... ...

Abstract	1. There is limited knowledge regarding the metabolism of megestrol acetate (MA), as it was approved by FDA in 1971, prior to the availability of modern tools for identifying specific drug-metabolizing enzymes. We determined the cytochrome P450s (P450s) and UDP-glucuronosyltransferases (UGTs) that metabolize MA, identified oxidative metabolites and determined pharmacologic activity at the progesterone, androgen and glucocorticoid receptors (PR, AR and GR, respectively). 2. Oxidative metabolites were produced using human liver microsomes (HLMs), and isolated for mass spectral (MS) and nuclear magnetic resonance (NMR) analyses. We screened recombinant P450s using MA at 62 μM (HLM K
MeSH term(s)	Cell Line, Tumor ; Cytochrome P-450 CYP3A/metabolism ; Cytochrome P-450 CYP3A Inhibitors/pharmacology ; Glucuronides/metabolism ; Humans ; Ketoconazole/pharmacology ; Kinetics ; Megestrol Acetate/chemistry ; Megestrol Acetate/metabolism ; Metabolome ; Microsomes, Liver/drug effects ; Microsomes, Liver/metabolism ; Oxidation-Reduction ; Prostate-Specific Antigen/metabolism ; Proton Magnetic Resonance Spectroscopy ; Receptors, Cytoplasmic and Nuclear/metabolism ; Recombinant Proteins/metabolism ; Substrate Specificity/drug effects ; Troleandomycin/pharmacology
Chemical Substances	Cytochrome P-450 CYP3A Inhibitors ; Glucuronides ; Receptors, Cytoplasmic and Nuclear ; Recombinant Proteins ; Troleandomycin (C4DZ64560D) ; Cytochrome P-450 CYP3A (EC 1.14.14.1) ; Prostate-Specific Antigen (EC 3.4.21.77) ; Ketoconazole (R9400W927I) ; Megestrol Acetate (TJ2M0FR8ES)
Language	English
Publishing date	2017-11-10
Publishing country	England
Document type	Journal Article
ZDB-ID	120287-x
ISSN	1366-5928 ; 0049-8254
ISSN (online)	1366-5928
ISSN	0049-8254
DOI	10.1080/00498254.2017.1386335
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 782: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Performance-based comparison of neonatal intubation training outcomes: simulator and live animal.

Andreatta, Pamela B / Klotz, Jessica J / Dooley-Hash, Suzanne L / Hauptman, Joe G / Biddinger, Bea / House, Joseph B

Advances in neonatal care : official journal of the National Association of Neonatal Nurses

2015 Volume 15, Issue 1, Page(s) 56–64

Abstract: The purpose of this article was to establish psychometric validity evidence for competency assessment instruments and to evaluate the impact of 2 forms of training on the abilities of clinicians to perform neonatal intubation. To inform the development ... ...

Abstract	The purpose of this article was to establish psychometric validity evidence for competency assessment instruments and to evaluate the impact of 2 forms of training on the abilities of clinicians to perform neonatal intubation. To inform the development of assessment instruments, we conducted comprehensive task analyses including each performance domain associated with neonatal intubation. Expert review confirmed content validity. Construct validity was established using the instruments to differentiate between the intubation performance abilities of practitioners (N = 294) with variable experience (novice through expert). Training outcomes were evaluated using a quasi-experimental design to evaluate performance differences between 294 subjects randomly assigned to 1 of 2 training groups. The training intervention followed American Heart Association Pediatric Advanced Life Support and Neonatal Resuscitation Program protocols with hands-on practice using either (1) live feline or (2) simulated feline models. Performance assessment data were captured before and directly following the training. All data were analyzed using analysis of variance with repeated measures and statistical significance set at P < .05. Content validity, reliability, and consistency evidence were established for each assessment instrument. Construct validity for each assessment instrument was supported by significantly higher scores for subjects with greater levels of experience, as compared with those with less experience (P = .000). Overall, subjects performed significantly better in each assessment domain, following the training intervention (P = .000). After controlling for experience level, there were no significant differences among the cognitive, performance, and self-efficacy outcomes between clinicians trained with live animal model or simulator model. Analysis of retention scores showed that simulator trained subjects had significantly higher performance scores after 18 weeks (P = .01) and 52 weeks (P = .001) and cognitive scores after 52 weeks (P = .001). The results of this study demonstrate the feasibility of using valid, reliable assessment instruments to assess clinician competency and self-efficacy in the performance of neonatal intubation. We demonstrated the relative equivalency of live animal and simulation-based models as tools to support acquisition of neonatal intubation skills. Retention of performance abilities was greater for subjects trained using the simulator, likely because it afforded greater opportunity for repeated practice. Outcomes in each assessment area were influenced by the previous intubation experience of participants. This suggests that neonatal intubation training programs could be tailored to the level of provider experience to make efficient use of time and educational resources. Future research focusing on the uses of assessment in the applied clinical environment, as well as identification of optimal training cycles for performance retention, is merited.
MeSH term(s)	Anesthesiology/education ; Animals ; Cats ; Clinical Competence ; Educational Measurement/methods ; Emergency Medicine/education ; Humans ; Infant, Newborn ; Intubation, Intratracheal ; Manikins ; Models, Animal ; Neonatal Nursing/education ; Neonatology/education ; Pediatrics/education ; Reproducibility of Results
Language	English
Publishing date	2015-02
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2171013-2
ISSN	1536-0911 ; 1536-0903
ISSN (online)	1536-0911
ISSN	1536-0903
DOI	10.1097/ANC.0000000000000130
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6005: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Prospective comparison of live evaluation and video review in the evaluation of operator performance in a pediatric emergency airway simulation.

House, Joseph B / Dooley-Hash, Suzanne / Kowalenko, Terry / Sikavitsas, Athina / Seeyave, Desiree M / Younger, John G / Hamstra, Stanley J / Nypaver, Michele M

Journal of graduate medical education

2013 Volume 4, Issue 3, Page(s) 312–316

Abstract: Introduction: Real-time assessment of operator performance during procedural simulation is a common practice that requires undivided attention by 1 or more reviewers, potentially over many repetitions of the same case.: Objective: To determine ... ...

Abstract	Introduction: Real-time assessment of operator performance during procedural simulation is a common practice that requires undivided attention by 1 or more reviewers, potentially over many repetitions of the same case. Objective: To determine whether reviewers display better interrater agreement of procedural competency when observing recorded, rather than live, performance; and to develop an assessment tool for pediatric rapid sequence intubation (pRSI). Methods: A framework of a previously established Objective Structured Assessment of Technical Skills (OSATS) tool was modified for pRSI. Emergency medicine residents (postgraduate year 1-4) were prospectively enrolled in a pRSI simulation scenario and evaluated by 2 live raters using the modified tool. Sessions were videotaped and reviewed by the same raters at least 4 months later. Raters were blinded to their initial rating. Interrater agreement was determined by using the Krippendorff generalized concordance method. Results: Overall interrater agreement for live review was 0.75 (95% confidence interval [CI], 0.72-0.78) and for video was 0.79 (95% CI, 0.73-0.82). Live review was significantly superior to video review in only 1 of the OSATS domains (Preparation) and was equivalent in the other domains. Intrarater agreement between the live and video evaluation was very good, greater than 0.75 for all raters, with a mean of 0.81 (95% CI, 0.76-0.85). Conclusion: The modified OSATS assessment tool demonstrated some evidence of validity in discriminating among levels of resident experience and high interreviewer reliability. With this tool, intrareviewer reliability was high between live and 4-months' delayed video review of the simulated procedure, which supports feasibility of delayed video review in resident assessment.
Language	English
Publishing date	2013-08-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2578612-X
ISSN	1949-8357 ; 1949-8349
ISSN (online)	1949-8357
ISSN	1949-8349
DOI	10.4300/JGME-D-11-00123.1
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Longer-term health and social care strategies for stroke survivors and their carers

Anne Forster / Seline Ozer / Thomas F Crocker / Allan House / Jenny Hewison / Elaine Roberts / Josie Dickerson / Gill Carter / Claire Hulme / Matthew Fay / Gillian Richardson / Alan Wright / Christopher McKevitt / Rosemary McEachan / Robbie Foy / Lorna Barnard / Lauren Moreau / Arvin Prashar / David Clarke /

Natasha Hardicre / Ivana Holloway / Richard Brindle / Jessica Hall / Louisa-Jane Burton / Ross Atkinson / Rebecca J Hawkins / Lesley Brown / Nicola Cornwall / Bryony Dawkins / David Meads / Laetitia Schmitt / Marie Fletcher / Michael Speed / Katie Grenfell / Suzanne Hartley / John Young / Amanda Farrin

Programme Grants for Applied Research, Vol 9, Iss

the LoTS2Care research programme including cluster feasibility RCT

2021 Volume 3

Abstract: Background: It is reported that the longer-term outcomes for stroke survivors are poor, with a range of unmet needs identified. Objectives: The aims were to develop and test a longer-term stroke care strategy focused on improving the quality of life of ... ...

Abstract	Background: It is reported that the longer-term outcomes for stroke survivors are poor, with a range of unmet needs identified. Objectives: The aims were to develop and test a longer-term stroke care strategy focused on improving the quality of life of stroke survivors and their carers by addressing unmet needs, and maintenance and enhancement of participation (i.e. involvement in life situations). Design: Five overlapping workstreams were undertaken – (1) refinement of content by semistructured interviews with stroke survivors and their carers and by a review of the literature to inform content and delivery of the care strategy; (2) exploration of service models by national survey and focus groups with purposely selected services; (3) intervention development by interaction with a reference group of stroke survivors, carers, and health and social care professionals; (4) refinement and pilot implementation of the developed intervention in three stroke services (case studies); and (5) a cluster randomised controlled feasibility trial in 10 stroke services across England and Wales. Setting: The intervention development work and feasibility trial were in stroke services (inclusive of primary, secondary, community and social care provision) across England and Wales. Participants: Participants were stroke survivors resident in the community and their carers, and health and social care professionals in the included stroke services. Data sources: Interviews with 28 stroke survivors and their carers at least 9 months post stroke ascertained their needs and the barriers to and facilitators of addressing those needs. Additional literature reviews identified 23 needs. No evidence-based interventions to address these needs were reported; self-management was highlighted as a possible delivery mechanism. In workstream 2, a national survey revealed that the most common model of stroke service provision was care up to 12 months post stroke, reported by 46 (40%) services. Thirty-five (30%) services provided care up to 6 months ...
Keywords	stroke ; quality of life ; activities of daily living ; health services research ; feasibility ; cluster randomised controlled trial ; action research ; process evaluation ; economic evaluation ; supported self-management ; Public aspects of medicine ; RA1-1270
Subject code	360
Language	English
Publishing date	2021-03-01T00:00:00Z
Publisher	NIHR Journals Library
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED