LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 2626

Search options

  1. Book: Anesthesia considerations for the oral and maxillofacial surgeon

    Mizukawa, Matthew / McKenna, Samuel J. / Vega, Luis G.

    2017  

    Author's details edited by Matthew Mizukawa, Samuel J. McKenna, Luis G. Vega
    Keywords Oral Surgical Procedures ; Anesthesia ; Ambulatory Surgical Procedures ; Intraoperative Complications / prevention & control ; Postoperative Complications / prevention & control
    Language English
    Size xiv, 467 Seiten, Illustrationen, Diagramme
    Publisher Quintessence Publishing
    Publishing place Hanover Park, IL
    Publishing country United States
    Document type Book
    HBZ-ID HT019550405
    ISBN 978-0-86715-713-0 ; 0-86715-713-5
    Database Catalogue ZB MED Medicine, Health

    Kategorien

  2. Article ; Online: Identifying the Optimal Heat Exposure Metric for Predicting the Physiological Response to Dry or Humid Heat Stress in Young and Older Adults: A Randomized Controlled Study.

    Foster, Josh / McKenna, Zachary J / Atkins, Whitey C / Jarrard, Caitlin P / Crandall, Craig G

    Environmental health perspectives

    2024  Volume 132, Issue 1, Page(s) 17701

    MeSH term(s) Humans ; Aged ; Aging/physiology ; Hot Temperature ; Heat Stress Disorders ; Heat-Shock Response/physiology ; Humidity
    Language English
    Publishing date 2024-01-12
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 195189-0
    ISSN 1552-9924 ; 0091-6765 ; 1078-0475
    ISSN (online) 1552-9924
    ISSN 0091-6765 ; 1078-0475
    DOI 10.1289/EHP13733
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: What's better for our health? Conducting protective actions during a nuclear emergency or accepting a certain radiation dose?

    Callen-Kovtunova, J / McKenna, T / Steinhauser, G

    Journal of radiological protection : official journal of the Society for Radiological Protection

    2022  Volume 42, Issue 2

    Abstract: ... balance between the benefit of a certain protective action (e.g. evacuation) and its risks is not always ... accounted for properly. Deaths and mental health problems have been associated with protective actions (e.g ...

    Abstract The threat caused by ionising radiation has resulted in the establishment of strict radiation protection guidelines. This is especially true for severe nuclear power plant (NPP) accident scenarios, which may involve the release of significant amounts of ionising radiation. However, we believe that the fine balance between the benefit of a certain protective action (e.g. evacuation) and its risks is not always accounted for properly. Deaths and mental health problems have been associated with protective actions (e.g. evacuation) implemented in the response to the Fukushima Daiichi (NPP) accident in 2011. The protective actions were implemented consistent with international recommendations, to reduce radiation-induced health effects, even though the off-site effective doses were too low to indicate that there would be any discernible radiation-induced health effects. In this paper, we will provide a first step for the development of tools to evaluate the risk of protective actions versus the radiation-induced health risk. Over 50 papers were selected as useful from more than 600 reviewed papers to characterise the health impact of protective actions taken during different emergencies (including, technical and natural emergencies). An analysis was performed comparing the radiation-induced health effects averted by protective actions with the health effects associated with the protective actions. We concentrated our analysis on deaths and mental health problems associated with protective actions compared with the inferred radiation-induced deaths averted by the protective actions. Our analysis is stated in terms of absolute risk (cases per 1000) of health effects to allow for a direct comparison. It indicates that taking protective actions consistent with dose criteria typically used in many countries could result in more excess deaths than the inferred radiation-induced deaths prevented, as well as resulting in mental health problems. We identified that residents of facilities for long stays and the elderly are particularly vulnerable and a significant number of the deaths among the general public are associated with a lack of emergency preparedness provisions.
    MeSH term(s) Aged ; Emergencies ; Fukushima Nuclear Accident ; Humans ; Japan ; Nuclear Power Plants ; Radiation Dosage ; Radiation Injuries/etiology ; Radiation Injuries/prevention & control ; Radiation Protection/methods
    Language English
    Publishing date 2022-03-25
    Publishing country England
    Document type Journal Article
    ZDB-ID 639411-5
    ISSN 1361-6498 ; 0952-4746
    ISSN (online) 1361-6498
    ISSN 0952-4746
    DOI 10.1088/1361-6498/ac5bde
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Cutaneous metastases as the presenting feature of lung cancer.

    Irvine, James / McKenna, Louise / Wylie, Grant

    BMJ case reports

    2023  Volume 16, Issue 12

    Abstract: Lung cancer is the second most common cancer diagnosed in men and women worldwide with the highest mortality. A rare site of metastases for lung cancer is the skin. Typically, the diagnosis is secure prior to developing cutaneous metastases. We present a ...

    Abstract Lung cancer is the second most common cancer diagnosed in men and women worldwide with the highest mortality. A rare site of metastases for lung cancer is the skin. Typically, the diagnosis is secure prior to developing cutaneous metastases. We present a case of a man in his mid-70s who presented to dermatology with cutaneous metastases. We outline the presentation, diagnostic workup and management of this case. We also review the literature of cutaneous metastases in lung cancer; highlighting the clinical need for a timely accurate diagnosis and the implication in terms of prognosis.
    MeSH term(s) Male ; Humans ; Female ; Lung Neoplasms/pathology ; Skin Neoplasms/pathology ; Prognosis ; Skin/pathology ; Neoplasms, Second Primary
    Language English
    Publishing date 2023-12-23
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-255225
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Haemoglobin mass responses and performance outcomes among high-performance swimmers following a 3-week live-high, train-high camp at 2320 m.

    Astridge, Daniel J / McKenna, Michael / Campbell, Adrian / Turner, Anthony P

    European journal of applied physiology

    2024  

    Abstract: ... increased significantly from 798 ± 182 g pre-ALT to 828 ± 187 g at 7 days post (p = 0.013) and 833 ± 205 g ...

    Abstract Aim: Greater quantification and characterisation of training load (TL) throughout Live-high, train-high (LHTH) altitude (ALT) training is required to identify periodisation strategies that may lead to physiological and performance improvements in swimmers.
    Purpose: This study aimed to examine the physiological responses and performance outcomes of 14 high-performance swimmers (FINA points: 836.0 ± 35.1) following 3 weeks of LHTH at 2320 m, while characterising the training load periodisation strategy adopted during the intervention.
    Methods: Haemoglobin (Hb) mass was measured pre-, 7 and 14 days post-ALT via CO rebreathing. Performance in each athlete's primary event at national standard meets were converted to FINA points and compared from pre-to-post-ALT. TL was quantified at sea level (SL) and ALT through session rating of perceived exertion (RPE), where duration of each session was multiplied by its RPE for each athlete, with all sessions totalled to give a weekly TL. Pre-to-post-ALT changes were evaluated using repeated-measures ANOVA.
    Results: Hb mass increased significantly from 798 ± 182 g pre-ALT to 828 ± 187 g at 7 days post (p = 0.013) and 833 ± 205 g 14 days post-ALT (p = 0.026). Weekly TL increased from SL (3179 ± 638 au) during week one (4797 ± 1349 au, p < 0.001) and week two (4373 ± 967 au, p < 0.001), but not week three (3511 ± 730 au, p = 0.149). No evidence of improved SL swimming performance was identified.
    Conclusion: A periodisation strategy characterised by a sharp spike in TL followed by a slight de-load towards the end of a LHTH intervention led to improved physiological characteristics but no change in the competitive performance of high-performance swimmers.
    Language English
    Publishing date 2024-03-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 124793-1
    ISSN 1439-6327 ; 1432-1025 ; 0301-5548 ; 1439-6319
    ISSN (online) 1439-6327 ; 1432-1025
    ISSN 0301-5548 ; 1439-6319
    DOI 10.1007/s00421-024-05454-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Microbial Biosurfactants: Antimicrobial Activity and Potential Biomedical and Therapeutic Exploits.

    Puyol McKenna, Patricia / Naughton, Patrick J / Dooley, James S G / Ternan, Nigel G / Lemoine, Patrick / Banat, Ibrahim M

    Pharmaceuticals (Basel, Switzerland)

    2024  Volume 17, Issue 1

    Abstract: The rapid emergence of multidrug-resistant pathogens worldwide has raised concerns regarding the effectiveness of conventional antibiotics. This can be observed in ESKAPE pathogens, among others, whose multiple resistance mechanisms have led to a ... ...

    Abstract The rapid emergence of multidrug-resistant pathogens worldwide has raised concerns regarding the effectiveness of conventional antibiotics. This can be observed in ESKAPE pathogens, among others, whose multiple resistance mechanisms have led to a reduction in effective treatment options. Innovative strategies aimed at mitigating the incidence of antibiotic-resistant pathogens encompass the potential use of biosurfactants. These surface-active agents comprise a group of unique amphiphilic molecules of microbial origin that are capable of interacting with the lipidic components of microorganisms. Biosurfactant interactions with different surfaces can affect their hydrophobic properties and as a result, their ability to alter microorganisms' adhesion abilities and consequent biofilm formation. Unlike synthetic surfactants, biosurfactants present low toxicity and high biodegradability and remain stable under temperature and pH extremes, making them potentially suitable for targeted use in medical and pharmaceutical applications. This review discusses the development of biosurfactants in biomedical and therapeutic uses as antimicrobial and antibiofilm agents, in addition to considering the potential synergistic effect of biosurfactants in combination with antibiotics. Furthermore, the anti-cancer and anti-viral potential of biosurfactants in relation to COVID-19 is also discussed.
    Language English
    Publishing date 2024-01-22
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph17010138
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: Sex Differences in Sympathetic Responses to Lower Body Negative Pressure.

    Jarrard, Caitlin P / Watso, Joseph C / Atkins, Whitley C / McKenna, Zachary J / Foster, Josh / Huang, Mu / Belval, Luke N / Crandall, Craig G

    Medicine and science in sports and exercise

    2024  

    Abstract: Introduction: Trauma-induced hemorrhage is a leading cause of death in prehospital settings. Experimental data demonstrate that females have a lower tolerance to simulated hemorrhage (i.e., central hypovolemia). However, the mechanism(s) underpinning ... ...

    Abstract Introduction: Trauma-induced hemorrhage is a leading cause of death in prehospital settings. Experimental data demonstrate that females have a lower tolerance to simulated hemorrhage (i.e., central hypovolemia). However, the mechanism(s) underpinning these responses are unknown. Therefore, this study aimed to compare autonomic cardiovascular responses during central hypovolemia between the sexes. We hypothesized that females would have a lower tolerance and smaller increase in muscle sympathetic nerve activity (MSNA) to simulated hemorrhage.
    Methods: Data from 17 females and 19 males, aged 19-45, were retrospectively analyzed. Participants completed a progressive lower-body negative pressure (LBNP) protocol to presyncope to simulate hemorrhagic tolerance with continuous measures of MSNA and beat-to-beat hemodynamic variables. We compared responses at baseline, at two LBNP stages (40 mmHg and 50 mmHg), and at immediately before presyncope. In addition, we compared responses at relative percentages (33%, 66%, and 100%) of hemorrhagic tolerance, calculated via the cumulative stress index (i.e., the sum of the product of time and pressure at each LBNP stage).
    Results: Females had lower tolerance to central hypovolemia (female: 561 ± 309 vs. male: 894 ± 304 min*mmHg [time*LBNP]; p = 0.003). At LBNP 40 mmHg and 50 mmHg, females had lower diastolic blood pressures (main effect of sex: p = 0.010). For the relative LBNP analysis, females exhibited lower MSNA burst frequency (main effect of sex: p = 0.016) accompanied by a lower total vascular conductance (sex: p = 0.028; main effect of sex).
    Conclusions: Females have a lower tolerance to central hypovolemia, which was accompanied by lower diastolic blood pressure at 40 and 50 mmHg LBNP. Notably, females had attenuated MSNA responses when assessed as relative LBNP tolerance time.
    Language English
    Publishing date 2024-01-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603994-7
    ISSN 1530-0315 ; 0195-9131 ; 0025-7990
    ISSN (online) 1530-0315
    ISSN 0195-9131 ; 0025-7990
    DOI 10.1249/MSS.0000000000003392
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: A systematic review of the association of Type I diabetes with sensorineural hearing loss.

    Mittal, Rahul / McKenna, Keelin / Keith, Grant / Lemos, Joana R N / Mittal, Jeenu / Hirani, Khemraj

    PloS one

    2024  Volume 19, Issue 2, Page(s) e0298457

    Abstract: Objectives: Type 1 diabetes (T1D) has been associated with several comorbidities such as ocular, renal, and cardiovascular complications. However, the effect of T1D on the auditory system and sensorineural hearing loss (SNHL) is still not clear. The aim ...

    Abstract Objectives: Type 1 diabetes (T1D) has been associated with several comorbidities such as ocular, renal, and cardiovascular complications. However, the effect of T1D on the auditory system and sensorineural hearing loss (SNHL) is still not clear. The aim of this study was to conduct a systematic review to evaluate whether T1D is associated with hearing impairment.
    Methods: The databases PubMed, Science Direct, Scopus, and EMBASE were searched in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria. Three reviewers independently screened, selected, and extracted data. The Joanna Briggs Institute (JBI) Critical Appraisal Tools for Analytical cross-sectional and case-control studies were used to perform quality assessment and risk of bias analysis on eligible studies.
    Results: After screening a total of 463 studies, 11 eligible original articles were included in the review to analyze the effects of T1D on the auditory system. The included studies comprised cross-sectional and case-control investigations. A total of 5,792 patients were evaluated across the 11 articles included. The majority of the studies showed that T1D was associated with hearing impairment compared to controls, including differences in PTAs and OAEs, increased mean hearing thresholds, altered acoustic reflex thresholds, and problems with the medial olivocochlear (MOC) reflex inhibitory effect. Significant risk factors included older age, increased disease duration, and higher HbA1C levels.
    Conclusions: This systematic review suggests that there is a correlation between T1D and impairment on the auditory system. A multidisciplinary collaboration between endocrinologists, otolaryngologists, and audiologists will lead to early detection of hearing impairment in people with T1D resulting in early intervention and better clinical outcomes in pursuit of improving the quality of life of affected individuals.
    Registration: This systematic review is registered in PROSPERO (CRD42023438576).
    MeSH term(s) Humans ; Diabetes Mellitus, Type 1/complications ; Quality of Life ; Cross-Sectional Studies ; Hearing Loss, Sensorineural/complications ; Hearing Loss
    Language English
    Publishing date 2024-02-09
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298457
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article ; Online: Recognizing and Adapting to Cultural Differences: Influence of International Educational Programs on Future Nursing and Midwifery Practice.

    Johnston, Jacqueline / McKenna, Lisa / Malik, Gulzar / Reisenhofer, Sonia

    Journal of transcultural nursing : official journal of the Transcultural Nursing Society

    2023  Volume 34, Issue 6, Page(s) 423–430

    Abstract: Introduction: International educational programs build cultural humility and safety skills in nursing and midwifery students; however, long-term outcomes of these programs are unclear. The purpose of this study was to explore the impact of international ...

    Abstract Introduction: International educational programs build cultural humility and safety skills in nursing and midwifery students; however, long-term outcomes of these programs are unclear. The purpose of this study was to explore the impact of international educational programs on nurses' and midwives' future professional practice.
    Method: Using grounded theory informed by Charmaz, 13 general nurses, two mental health nurses, three midwives, and four dual-qualified nurse/midwives across eight different countries were interviewed. Three categories evolved from the analysis. This article reports on the category
    Findings: Participants developed cultural safety and awareness from participation in programs extending into future practice. Experiencing and adapting to cultural similarities and differences, they developed culturally congruent practices many years after program completion.
    Discussion: International programs contributed to participants' professional practice. Positive and ongoing influences are important for employers to promote patient safety and culturally congruent quality care. Findings are also relevant for education providers to inform quality cultural learning.
    MeSH term(s) Pregnancy ; Humans ; Female ; Midwifery ; Nurse Midwives/psychology ; Culturally Competent Care ; Learning ; Students, Nursing/psychology
    Language English
    Publishing date 2023-09-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1291524-5
    ISSN 1552-7832 ; 1043-6596
    ISSN (online) 1552-7832
    ISSN 1043-6596
    DOI 10.1177/10436596231198276
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Experiences of nurses and midwives with disabilities: A scoping review.

    Baker, Christine / Malik, Gulzar / Davis, Jenny / McKenna, Lisa

    Journal of advanced nursing

    2023  Volume 79, Issue 11, Page(s) 4149–4163

    Abstract: Aim: To identify the extent and type of evidence exploring the workplace experiences of nurses and midwives with disabilities.: Design: Scoping Review.: Data sources: Four electronic databases were systematically searched in February 2022 to ... ...

    Abstract Aim: To identify the extent and type of evidence exploring the workplace experiences of nurses and midwives with disabilities.
    Design: Scoping Review.
    Data sources: Four electronic databases were systematically searched in February 2022 to identify studies discussing the experiences of nurses and midwives with disabilities, published between 2012 and 2022. Google Scholar and Theses Global were also searched.
    Review methods: All search results, irrespective of their format, were uploaded to Covidence to assist with the selection of evidence. Studies discussing the experiences of nurses and midwives with disabilities were included. Two reviewers conducted screening and data extraction independently, and a third reviewer resolved conflicts.
    Results: Searches identified 130 studies. After screening for title and abstract, full-text review identified 23 studies for data extraction and analysis. Data were summarized and presented in tabular form under two categories (1) workplace experiences and (2) impact in the workplace. Results were presented in a descriptive, narrative form with accompanying tables.
    Conclusion: The nurse or midwife can be impacted significantly by disability. Currently, little is known about the workplace experiences of nurses and midwives with disabilities. Therefore, a better understanding of the experiences of the nurse and midwives with disabilities is important to increase diversity, equity, accessibility, and inclusion.
    Impact: Shortage of nurses and midwives worldwide highlights the need to understand why nurses and midwives with disabilities decide to leave the profession. Further research exploring the experiences of nurses or midwives with disabilities will help identify support requirements, develop frameworks for reasonable adjustment accommodations, and assist with future workforce planning. The EQUATOR guidelines for PRISMA have been met. No Patient or Public Contribution.
    Language English
    Publishing date 2023-08-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 197634-5
    ISSN 1365-2648 ; 0309-2402
    ISSN (online) 1365-2648
    ISSN 0309-2402
    DOI 10.1111/jan.15802
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top