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Article ; Online: Analgesic effect of Botulinum toxin in neuropathic pain is sodium channel independent.

Kesdoğan, Aylin B / Neureiter, Anika / Gaebler, Arnim J / Kalia, Anil K / Körner, Jannis / Lampert, Angelika

2024 , Page(s) 109967

Abstract: ... suffering from a hereditary neuropathic pain syndrome (inherited erythromelalgia) carrying the Nav1.7/p ...

Abstract	Botulinum neurotoxin type A BoNT/A is used off-label as a third line therapy for neuropathic pain. However, the mechanism of action remains unclear. In recent years, the role of voltage-gated sodium channels (Nav) in neuropathic pain became evident and it was suggested that block of sodium channels by BoNT/A would contribute to its analgesic effect. We assessed sodium channel function in the presence of BoNT/A in heterologously expressed Nav1.7, Nav1.3, and the neuronal cell line ND7/23 by high throughput automated and manual patch-clamp. We used both the full protein and the isolated catalytic light chain LC/A for acute or long-term extracellular or intracellular exposure. To assess the toxin's effect in a human cellular system, we differentiated induced pluripotent stem cells (iPSC) into sensory neurons from a healthy control and a patient suffering from a hereditary neuropathic pain syndrome (inherited erythromelalgia) carrying the Nav1.7/p.Q875E-mutation and carried out multi electrode array measurements. Both BoNT/A and the isolated catalytic light chain LC/A showed limited effects in heterologous expression systems and the neuronal cell line ND7/23. Spontaneous activity in iPSC derived sensory neurons remained unaltered upon BoNT/A exposure both in neurons from the healthy control and the mutation carrying patient. BoNT/A may not specifically be beneficial in pain syndromes linked to sodium channel variants. The favorable effects of BoNT/A in neuropathic pain are likely based on mechanisms other than sodium channel blockage and new approaches to understand BoNT/A's therapeutic effects are necessary.
Language	English
Publishing date	2024-04-22
Publishing country	England
Document type	Journal Article
ZDB-ID	218272-5
ISSN	1873-7064 ; 0028-3908
ISSN (online)	1873-7064
ISSN	0028-3908
DOI	10.1016/j.neuropharm.2024.109967
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Article ; Online: Kardiorespiratorische Effekte perioperativer Positionierungsmaßnahmen.

Zeuzem-Lampert, C / Groene, P / Brummer, V / Hofmann-Kiefer, K

Der Anaesthesist

2019 Volume 68, Issue 12, Page(s) 805–813

Abstract: The supine position is still the most frequently used type of positioning during surgical procedures. Positions other than the supine position lead to physiological alterations that have a relevant influence on the course of anesthesia and surgery. As a ... ...

Title translation	Cardiorespiratory effects of perioperative positioning techniques.
Abstract	The supine position is still the most frequently used type of positioning during surgical procedures. Positions other than the supine position lead to physiological alterations that have a relevant influence on the course of anesthesia and surgery. As a matter of principle, hemodynamic stability is at risk because venous blood is pooled in the lower positioned body parts. In addition, head down positions (Trendelenburg position) may lead to an impairment of respiratory function by reducing lung volumes as well as lung compliance. Upright positions (beach chair position) are characterized by a relative hypovolemia accompanied by a reduction of mean arterial pressure, cardiac output and stroke volume, whereas pulmonary functions remain unchanged. Some severe adverse events have been described in the literature (e.g. intraoperative apoplexy, postoperative blindness). The pathophysiological principles and effects of hemodynamic alterations as well as potential strategies to avoid complications are presented and discussed in this lead article. Head down positions, especially the Trendelenburg position, cause a relative (intrathoracic) hypervolemia and an increase in cardiac preload that is usually well-tolerated in patients without heart problems; however, the Trendelenburg position, especially if combined with a capnoperitoneum, significantly impairs pulmonary function, can have a negative effect on intracerebral pressure and may reduce blood flow of intra-abdominal organs. The pathophysiological intraoperative changes caused by Trendelenburg positioning are described and approaches suitable for risk reduction are discussed. The prone position and lateral decubitus position have little influence on the intraoperative homeostasis. Nevertheless, there is an ongoing discussion concerning the efficacy of a 15° left lateral position during caesarean section, which is also discussed in a separate section of this review.
MeSH term(s)	Blood Pressure ; Cardiac Output ; Cesarean Section ; Head-Down Tilt/physiology ; Heart Rate ; Hemodynamics/physiology ; Humans ; Hypovolemia ; Lung Compliance ; Patient Positioning/methods ; Prone Position/physiology ; Stroke Volume
Language	German
Publishing date	2019-11-11
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	260-4
ISSN	1432-055X ; 0003-2417
ISSN (online)	1432-055X
ISSN	0003-2417
DOI	10.1007/s00101-019-00674-9
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Article ; Online: Postoperative cognitive dysfunction after beach chair positioning compared to supine position in orthopaedic surgery in the elderly.

Groene, Philipp / Schaller, Tanja / Zeuzem-Lampert, Catharina / Rudy, Margret / Ockert, Ben / Siebenbürger, Georg / Saller, Thomas / Conzen, Peter / Hofmann-Kiefer, Klaus

Archives of orthopaedic and trauma surgery

2023 Volume 144, Issue 2, Page(s) 575–581

Abstract: ... in both groups. POCD after 1 week occurred in 10.5% of SP patients and in 21.1% of BCP patients (p = 0.123 ... 5.3%; p = 0.463). 12/18 patients with POCD showed changes in their Word Fluency Tests ... 57% (51/61); p = 0.671).: Conclusion: POCD at 1 week after surgery tended to occur more often ...

Abstract	Introduction: Postoperative cognitive dysfunction (POCD) occurs in up to 26% of patients older than 60 years 1 week after non-cardiac surgery. Intraoperative beach chair positioning (BCP) is advantageous for some types of shoulder surgery. However, this kind of positioning leads to a downward bound redistribution of blood volume, with possible hypoperfusion of the brain. We hypothesized that patients > 60 years undergoing orthopaedic shoulder surgery in a BCP might experience more POCD than patients operated in the supine position (SP). Material and methods: A single-centre, prospective observational trial of 114 orthopaedic patients was performed. Study groups were established according to the type of intraoperative positioning. Anaesthesiological management was carried out similarly in both groups, including types of anaesthetics and blood pressure levels. POCD was evaluated using the Trail Making Test, the Letter-Number Span and the Regensburger Word Fluency Test. The frequency of POCD 1 week after surgery was considered primary outcome. Results: Baseline characteristics, including duration of surgery, were comparable in both groups. POCD after 1 week occurred in 10.5% of SP patients and in 21.1% of BCP patients (p = 0.123; hazard ratio 2.0 (CI 95% 0.794-5.038)). After 4 weeks, the incidence of POCD decreased (SP: 8.8% vs. BCP: 5.3%; p = 0.463). 12/18 patients with POCD showed changes in their Word Fluency Tests. Near-infrared spectroscopy (NIRS) values were not lower in patients with POCD compared to those without POCD (54% (50/61) vs. 57% (51/61); p = 0.671). Conclusion: POCD at 1 week after surgery tended to occur more often in patients operated in beach chair position compared to patients in supine position without being statistically significant.
MeSH term(s)	Aged ; Humans ; Orthopedic Procedures ; Orthopedics ; Oxygen ; Patient Positioning/methods ; Postoperative Cognitive Complications ; Supine Position ; Prospective Studies
Chemical Substances	Oxygen (S88TT14065)
Language	English
Publishing date	2023-10-27
Publishing country	Germany
Document type	Observational Study ; Journal Article
ZDB-ID	80407-1
ISSN	1434-3916 ; 0003-9330 ; 0344-8444
ISSN (online)	1434-3916
ISSN	0003-9330 ; 0344-8444
DOI	10.1007/s00402-023-05109-0
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Article ; Online: Patient-specific 3D-printed mini-versus reconstruction plates for free flap fixation at the mandible: Retrospective study of clinical outcomes and complication rates.

Kreutzer, Kilian / Lampert, Philipp / Doll, Christian / Voss, Jan O / Koerdt, Steffen / Heiland, Max / Steffen, Claudius / Rendenbach, Carsten

Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery

2023 Volume 51, Issue 10, Page(s) 621–628

Abstract: ... p < 0.001) and in an outpatient setting (p = 0.002). Univariate analysis showed a higher fistula ... rate with reconstruction plates (p = 0.037). Multivariate analysis showed no significant differences ... in complications. Case-control matching demonstrated significantly lower rates of fistula (p = 0.017) and non-union ...

Abstract	This study aimed to compare the clinical outcomes and complication rates of patient-specific 3D-printed mini- and reconstruction plates for free flap fixation in mandibular reconstruction. A retrospective monocentric study was carried out between April 2017 and December 2021 to analyze patients undergoing immediate mandibular reconstruction using fibula free flaps and osteosynthesis using patient-specific 3D-printed implants. Eighty-three patients with a mean age of 63.6 years were included. The mean follow-up period was 18.5 months. Patient-specific 3D-printed plates were designed as reconstruction plates (38 patients), miniplates (21 patients) or a combination of reconstruction- and miniplates (24 patients). With miniplates, plate removal was performed significantly more often via an intraoral approach (p < 0.001) and in an outpatient setting (p = 0.002). Univariate analysis showed a higher fistula rate with reconstruction plates (p = 0.037). Multivariate analysis showed no significant differences in complications. Case-control matching demonstrated significantly lower rates of fistula (p = 0.017) and non-union (p = 0.029) in the combined group. This retrospective study shows a tendency towards reduced complication rates with patient-specific 3D-printed miniplates in comparison to patient-specific 3D-printed reconstruction plates for immediate mandibular reconstruction with fibula free flaps.
MeSH term(s)	Humans ; Middle Aged ; Free Tissue Flaps ; Retrospective Studies ; Mandible/surgery ; Mandibular Reconstruction ; Bone Plates ; Fistula ; Printing, Three-Dimensional
Language	English
Publishing date	2023-10-06
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	91267-0
ISSN	1878-4119 ; 1010-5182 ; 0301-0503
ISSN (online)	1878-4119
ISSN	1010-5182 ; 0301-0503
DOI	10.1016/j.jcms.2023.09.019
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Article ; Online: A large, multi-center survey assessing health, social support, literacy, and self-management resources in patients with heart failure.

Chamberlain, Alanna M / Hade, Erinn M / Haller, Irina V / Horne, Benjamin D / Benziger, Catherine P / Lampert, Brent C / Rasmusson, Kismet D / Boddicker, Kimberly / Manemann, Sheila M / Roger, Véronique L

BMC public health

2024 Volume 24, Issue 1, Page(s) 1141

Abstract: Background: Most patients with heart failure (HF) have multimorbidity which may cause difficulties with self-management. Understanding the resources patients draw upon to effectively manage their health is fundamental to designing new practice models to ...

Abstract	Background: Most patients with heart failure (HF) have multimorbidity which may cause difficulties with self-management. Understanding the resources patients draw upon to effectively manage their health is fundamental to designing new practice models to improve outcomes in HF. We describe the rationale, conceptual framework, and implementation of a multi-center survey of HF patients, characterize differences between responders and non-responders, and summarize patient characteristics and responses to the survey constructs among responders. Methods: This was a multi-center cross-sectional survey study with linked electronic health record (EHR) data. Our survey was guided by the Chronic Care Model to understand the distribution of patient-centric factors, including health literacy, social support, self-management, and functional and mental status in patients with HF. Most questions were from existing validated questionnaires. The survey was administered to HF patients aged ≥ 30 years from 4 health systems in PCORnet® (the National Patient-Centered Clinical Research Network): Essentia Health, Intermountain Health, Mayo Clinic, and The Ohio State University. Each health system mapped their EHR data to a standardized PCORnet Common Data Model, which was used to extract demographic and clinical data on survey responders and non-responders. Results: Across the 4 sites, 10,662 patients with HF were invited to participate, and 3330 completed the survey (response rate: 31%). Responders were older (74 vs. 71 years; standardized difference (95% CI): 0.18 (0.13, 0.22)), less racially diverse (3% vs. 12% non-White; standardized difference (95% CI): -0.32 (-0.36, -0.28)), and had higher prevalence of many chronic conditions than non-responders, and thus may not be representative of all HF patients. The internal reliability of the validated questionnaires in our survey was good (range of Cronbach's alpha: 0.50-0.96). Responders reported their health was generally good or fair, they frequently had cardiovascular comorbidities, > 50% had difficulty climbing stairs, and > 10% reported difficulties with bathing, preparing meals, and using transportation. Nearly 80% of patients had family or friends sit with them during a doctor visit, and 54% managed their health by themselves. Patients reported generally low perceived support for self-management related to exercise and diet. Conclusions: More than half of patients with HF managed their health by themselves. Increased understanding of self-management resources may guide the development of interventions to improve HF outcomes.
MeSH term(s)	Humans ; Heart Failure/therapy ; Heart Failure/psychology ; Cross-Sectional Studies ; Female ; Male ; Aged ; Health Literacy/statistics & numerical data ; Middle Aged ; Self-Management ; Social Support ; Adult ; Surveys and Questionnaires ; Aged, 80 and over ; Health Status
Language	English
Publishing date	2024-04-24
Publishing country	England
Document type	Journal Article ; Multicenter Study ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-024-18533-7
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Article ; Online: Facultative parthenogenesis in vertebrates: reproductive error or chance?

Lampert, K P

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation

2008 Volume 2, Issue 6, Page(s) 290–301

Abstract: Parthenogenesis, the development of an embryo from a female gamete without any contribution of a male gamete, is very rare in vertebrates. Parthenogenetically reproducing species have, so far, only been found in the Squamate reptiles (lizards and snakes). ...

Abstract	Parthenogenesis, the development of an embryo from a female gamete without any contribution of a male gamete, is very rare in vertebrates. Parthenogenetically reproducing species have, so far, only been found in the Squamate reptiles (lizards and snakes). Facultative parthenogenesis, switching between sexual and clonal reproduction, although quite common in invertebrates, e.g. Daphnia and aphids, seems to be even rarer in vertebrates. However, isolated cases of parthenogenetic development have been reported in all vertebrate groups. Facultative parthenogenesis in vertebrates has only been found in captive animals but might simply have been overlooked in natural populations. Even though its evolutionary impact is hard to determine and very likely varies depending on the ploidy restoration mechanisms and sex-determining mechanisms involved, facultative parthenogenesis is already discussed in conservation biology and medical research. To raise interest for facultative parthenogenesis especially in evolutionary biology, I summarize the current knowledge about facultative parthenogenesis in the different vertebrate groups, introduce mechanisms of diploid oocyte formation and discuss the genetic consequences and potential evolutionary impact of facultative parthenogenesis in vertebrates.
MeSH term(s)	Animals ; Biological Evolution ; Female ; Male ; Parthenogenesis/genetics ; Parthenogenesis/physiology ; Reproduction/genetics ; Reproduction/physiology ; Vertebrates/physiology
Language	English
Publishing date	2008
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2253672-3
ISSN	1661-5433 ; 1661-5425
ISSN (online)	1661-5433
ISSN	1661-5425
DOI	10.1159/000195678
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Article ; Online: Spielerische Ansätze in Prävention und Gesundheitsförderung: Serious Games und Gamification.

Tolks, Daniel / Lampert, Claudia / Dadaczynski, Kevin / Maslon, Eveline / Paulus, Peter / Sailer, Michael

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz

2020 Volume 63, Issue 6, Page(s) 698–707

Abstract: Digital game-based approaches can be used in the field of prevention and health promotion, for example to promote health-related information or to foster health behavior change. The two most relevant game approaches are "serious games" (games with a ... ...

Title translation	Game-based approaches to prevention and health promotion: serious games and gamification.
Abstract	Digital game-based approaches can be used in the field of prevention and health promotion, for example to promote health-related information or to foster health behavior change. The two most relevant game approaches are "serious games" (games with a serious background) and "gamification" (the application of game-typical elements in nongame contexts). The term serious games is used to describe games that are used to convey serious content, such as health issues. Gamification uses game-design elements such as points, leaderboards, awards, profile design, and team events to increase motivation and performance, for example in learning environments. This narrative article examines the mode of action and study situation as well as the advantages and disadvantages of playful applications in prevention and health promotion and exemplifies some of these applications.Serious games and gamification show great potential in prevention and health promotion. Especially in the case of target groups that are difficult to reach and disinterested, a direct connection to their living environment can be established. The foundations for the effective use of playful approaches in the work and training of health professionals are their already high level of familiarity with the medium of games and that games directly address the basic psychological needs to increase motivation.
MeSH term(s)	Germany ; Health Behavior ; Health Education/methods ; Health Promotion/methods ; Humans ; Learning ; Motivation ; Video Games/psychology
Language	German
Publishing date	2020-05-25
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	1461973-8
ISSN	1437-1588 ; 1436-9990
ISSN (online)	1437-1588
ISSN	1436-9990
DOI	10.1007/s00103-020-03156-1
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Article ; Online: Should we Oppose or Combine Waveforms for Spinal Cord Stimulation in PSPS-T2 Patients? A Prospective Randomized Crossover Trial (MULTIWAVE Study).

Rigoard, Philippe / Ounajim, Amine / Moens, Maarten / Goudman, Lisa / Roulaud, Manuel / Lorgeoux, Bertille / Baron, Sandrine / Nivole, Kévin / Many, Mathilde / Lampert, Lucie / David, Romain / Billot, Maxime

The journal of pain

2023 Volume 24, Issue 12, Page(s) 2319–2339

Abstract: ... the follow-up periods. No difference between the waveforms was observed in this study (P = .08). SCS led ...

Abstract	Refractory persistent spinal pain syndrome after surgery (PSPS-T2) can be successfully addressed by spinal cord stimulation (SCS). While conventional stimulation generates paresthesia, recent systems enable the delivery of paresthesia-free stimulation. Studies have claimed non-inferiority/superiority of selected paresthesia-free stimulation compared with paresthesia-based stimulation, but the comparative efficacy between different waveforms still needs to be determined in a given patient. We designed a randomized controlled 3-month crossover trial to compare pain relief of paresthesia-based stimulation versus high frequency versus burst in 28 PSPS-T2 patients implanted with multiwave SCS systems. Our secondary objectives were to determine the efficacy of these 3 waveforms on pain surface, quality of life, functional capacity, psychological distress, and validated composite multidimensional clinical response index to provide holistic comparisons at 3-, 6-, 9-, and 15-month post-randomization. The preferred stimulation modality was documented during the follow-up periods. No difference between the waveforms was observed in this study (P = .08). SCS led to significant pain relief, quality of life improvement, improvement of multidimensional clinical response index, and of all other clinical outcomes at all follow-up visits. Forty-four percent of the patients chose to keep the paresthesia-based stimulation modality after the 15-month follow-up period. By giving the possibility to switch and/or to combine several waveforms, the overall rate of SCS responders further increased with 25%. In this study, high frequency or burst do not appear superior to paresthesia-based stimulation, wherefore paresthesia-based stimulation should still be considered as a valid option. However, combining paresthesia-based stimulation with paresthesia-free stimulation, through personalized multiwave therapy, might significantly improve SCS responses. PERSPECTIVE: This article assesses clinical SCS efficacy on pain relief, by comparing paresthesia-based stimulation and paresthesia-free stimulation (including high frequency and burst) modalities in patient presenting with PSPS-T2. Switching and/or combining waveforms contribute to increasing the global SCS responders rate.
MeSH term(s)	Humans ; Spinal Cord Stimulation/methods ; Cross-Over Studies ; Paresthesia/etiology ; Paresthesia/therapy ; Prospective Studies ; Quality of Life ; Pain Measurement ; Treatment Outcome ; Pain, Intractable ; Spinal Cord ; Chronic Pain
Language	English
Publishing date	2023-07-18
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2018789-0
ISSN	1528-8447 ; 1526-5900
ISSN (online)	1528-8447
ISSN	1526-5900
DOI	10.1016/j.jpain.2023.07.015
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Article: Facultative Parthenogenesis in Vertebrates: Reproductive Error or Chance?

Lampert, K.P.

Sexual Development

2009 Volume 2, Issue 6, Page(s) 290–301

Institution	Evolutionary Ecology and Biodiversity of Animals, University of Bochum, Bochum, Germany
Abstract	Parthenogenesis, the development of an embryo from a female gamete without any contribution of a male gamete, is very rare in vertebrates. Parthenogenetically reproducing species have, so far, only been found in the Squamate reptiles (lizards and snakes). Facultative parthenogenesis, switching between sexual and clonal reproduction, although quite common in invertebrates, e.g. Daphnia and aphids, seems to be even rarer in vertebrates. However, isolated cases of parthenogenetic development have been reported in all vertebrate groups. Facultative parthenogenesis in vertebrates has only been found in captive animals but might simply have been overlooked in natural populations. Even though its evolutionary impact is hard to determine and very likely varies depending on the ploidy restoration mechanisms and sex-determining mechanisms involved, facultative parthenogenesis is already discussed in conservation biology and medical research. To raise interest for facultative parthenogenesis especially in evolutionary biology, I summarize the current knowledge about facultative parthenogenesis in the different vertebrate groups, introduce mechanisms of diploid oocyte formation and discuss the genetic consequences and potential evolutionary impact of facultative parthenogenesis in vertebrates.
Keywords	Sex determination ; Terminal fusion ; All-female species ; Apomixis ; Automixis ; Clonal reproduction
Language	English
Publishing date	2009-03-10
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Review Article
ZDB-ID	2253672-3
ISSN	1661-5433 ; 1661-5425
ISSN (online)	1661-5433
ISSN	1661-5425
DOI	10.1159/000195678
Database	Karger publisher's database

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Article ; Online: Novel uses for implanted haemodynamic monitoring in adults with subaortic right ventricles.

Marshall V, William H / Mah, May Ling / DeSalvo, Jennifer / Rajpal, Saurabh / Lastinger, Lauren T / Salavitabar, Arash / Armstrong, Aimee K / Berman, Darren / Lampert, Brent / Wright, Lydia K / Hickey, Jenne / Metzger, Rachel / Nandi, Deipanjan / Gajarski, Robert / Daniels, Curt J

Heart (British Cardiac Society)

2024 Volume 110, Issue 7, Page(s) 491–499

Abstract: ... similar to the year prior to IHM (median 0 (IQR 0-1.0) before vs 0 (0-0.8) after, p=0.984). Device ...

Abstract	Background: Pulmonary hypertension (PH) is a common complication in patients with complete dextro-transposition of the great arteries (TGA) after atrial switch (D-TGA/AS) and congenitally corrected TGA (ccTGA). In this population with subaortic right ventricles (sRVs), echocardiography is a poor screening tool for PH; implantable invasive haemodynamic monitoring (IHM) could be used for this purpose, but data are limited. The aim of this study is to report on novel uses of IHM in patients with sRV. Methods: This retrospective study describes the uses of IHM, impact of IHM on heart failure hospitalisation (HFH) and device-related complications in adults with sRV from a single centre (2015-2022). Results: IHM was placed in 18 patients with sRV (median age 43 (range 30-54) years, 8 female, 16 with D-TGA/AS, 2 with ccTGA); 16 had moderate or severe sRV systolic dysfunction, 13 had PH on catheterisation. IHM was used for (1) Medical therapy titration, (2) Medical management after ventricular assist device in patients with transplant-limiting PH and (3) Serial monitoring of pulmonary artery pressures without repeat catheterisations to help identify the optimal time for heart transplant referral. In follow-up (median 23 months), HFHs/year were similar to the year prior to IHM (median 0 (IQR 0-1.0) before vs 0 (0-0.8) after, p=0.984). Device migration occurred in one, without long-term sequelae. Conclusions: Uses of IHM in patients with sRV are described which may minimise the need for serial catheterisations in a population where PH is prevalent. HFHs were low overall but not impacted by IHM. One device-related complication occurred without long-term consequence.
MeSH term(s)	Adult ; Humans ; Female ; Middle Aged ; Transposition of Great Vessels ; Retrospective Studies ; Heart Ventricles ; Hemodynamic Monitoring ; Congenitally Corrected Transposition of the Great Arteries
Language	English
Publishing date	2024-03-12
Publishing country	England
Document type	Journal Article
ZDB-ID	1303417-0
ISSN	1468-201X ; 1355-6037
ISSN (online)	1468-201X
ISSN	1355-6037
DOI	10.1136/heartjnl-2023-323206
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In stock of ZB MED Cologne/Königswinter

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In stock of ZB MED Cologne/Königswinter

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Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito