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  1. Article: Authentication of Golden-Berry P. ginseng Cultivar'Gumpoong' from a Landrace'Hwangsook' Based on Pooling Method Using Chloroplast-Derived Markers Ho Jun Joh, Nam-Hoon Kim, Murukarthick Jayakodi, Woojong Jang, Jee Young Park, Young Chang Kim,

    In, Jun-gyo / Yang, Tae-jin

    Plant breeding and biotechnology

    2017  Volume 5, Issue 1, Page(s) 16

    Language English
    Document type Article
    ZDB-ID 2827037-X
    ISSN 2287-9358
    Database Current Contents Nutrition, Environment, Agriculture

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    In stock of ZB MED Bonn / Germany

    Z 7958: Show issues

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  2. Article ; Online: Lateral Deviation of the Hyoid Bone and Thyroid Cartilage Influences Prevertebral Soft-Tissue Swelling and Dysphagia After Anterior Cervical Diskectomy and Fusion.

    Yang, Jae Jun / Lee, Jin-Bog / Choi, Jun-Young

    Neurosurgery

    2024  

    Abstract: Background and objectives: Prevertebral soft-tissue swelling (PSTS) after anterior cervical diskectomy and fusion (ACDF) is known to be influenced by several factors. We considered the effect of lateral deviation on the traction force and attempted to ... ...

    Abstract Background and objectives: Prevertebral soft-tissue swelling (PSTS) after anterior cervical diskectomy and fusion (ACDF) is known to be influenced by several factors. We considered the effect of lateral deviation on the traction force and attempted to find a relationship with the PSTS. This study was designed to evaluate the preoperative lateral deviation of the hyoid bone and thyroid cartilage and its effect on PSTS, airway collapse, and clinical outcomes after ACDF.
    Methods: Preoperative lateral deviations of the hyoid bone and thyroid cartilage at the superior cornu and inferior cornu were measured. To assess the effect of lateral deviation, patients who underwent 1 or 2 level ACDF with the left-sided approach were divided into a deviation group (left-sided deviation >5 mm or >10 mm) and a nondeviation group (left-sided deviation <5 mm or <10 mm). Difference of preoperative and postoperative PSTS (dPSTS), airway collapse, dysphagia score, and Neck Disability Index were compared between the 2 groups.
    Results: Lateral deviation was measured in 290 patients, and 145 were enrolled to assess the effect of lateral deviation. Left-sided deviation was more common than right-sided deviation in all 3 structures (the hyoid bone, superior cornu, and inferior cornu of the thyroid cartilage). The deviation group demonstrated a significantly larger dPSTS at the C3 and C4 levels, more airway collapse at the C4 level, and a higher dysphagia score. There was no significant difference in the Neck Disability Index between the 2 groups. Lateral deviation significantly correlated with dPSTS (C3, C4, C5, and C6 levels) and airway collapse (C3 and C4 levels).
    Conclusion: A left-sided deviation of more than 5 mm of the hyoid bone or thyroid cartilage discouraged the left-sided approach for ACDF because of the aggravation of dPSTS, airway collapse, and dysphagia postoperatively.
    Language English
    Publishing date 2024-04-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 135446-2
    ISSN 1524-4040 ; 0148-396X
    ISSN (online) 1524-4040
    ISSN 0148-396X
    DOI 10.1227/neu.0000000000002963
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1424: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 539: Show issues

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  3. Article: Expression Profiles of Hypoxia-Related Genes of Cancers Originating from Anatomically Similar Locations Using TCGA Database Analysis.

    Bae, Hye Lim / Jeong, Kyeonghun / Yang, Suna / Jun, Hyeji / Kim, Kwangsoo / Chai, Young Jun

    Medicines (Basel, Switzerland)

    2023  Volume 11, Issue 1

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2023-12-31
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2777965-8
    ISSN 2305-6320
    ISSN 2305-6320
    DOI 10.3390/medicines11010002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Anticoagulation in patients with end-stage kidney disease and atrial fibrillation: a national population-based study.

    Kim, Deok-Gie / Kim, Sung Hwa / Park, Sung Yong / Han, Byoung Geun / Kim, Jae Seok / Yang, Jae Won / Park, Young Jun / Lee, Jun Young

    Clinical kidney journal

    2024  Volume 17, Issue 2, Page(s) sfae029

    Abstract: Background: The prevalence of atrial fibrillation (AF) in patients with end-stage kidney disease (ESKD) is high and increasing. However, evidence regarding oral anticoagulant (OAC) use in these patients is insufficient and conflicting.: Methods: This ...

    Abstract Background: The prevalence of atrial fibrillation (AF) in patients with end-stage kidney disease (ESKD) is high and increasing. However, evidence regarding oral anticoagulant (OAC) use in these patients is insufficient and conflicting.
    Methods: This retrospective cohort study included patients in the Korea National Health Insurance System diagnosed with AF after ESKD onset from January 2007 to December 2017. The primary outcome was all-cause death. Secondary outcomes were ischaemic stroke, hospitalization for major bleeding and major adverse cardiovascular events (MACE). Outcomes were compared between OAC users and non-users using 6-month landmark analysis and 1:3 propensity score matching (PSM).
    Results: Among patients with ESKD and AF, the number of prescribed OACs increased 2.3-fold from 2012 (
    Conclusions: In patients with ESKD and AF, OACs were associated with reduced all-cause death, ischaemic stroke and MACE.
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfae029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6587: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Significant wave height prediction from X-band marine radar images using deep learning with 3D convolutions

    Ji-Woo Kwon / Won-Du Chang / Young Jun Yang

    PLoS ONE, Vol 18, Iss

    2023  Volume 10

    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  6. Article: Role of Recurrence Pattern Multiplicity in Predicting Post-recurrence Survival in Patients Who Underwent Curative Gastrectomy for Gastric Cancer.

    Yang, Jun-Young / Park, Ji-Hyeon / Choi, Seung Joon / Lee, Woon Kee

    Journal of gastric cancer

    2024  Volume 24, Issue 2, Page(s) 231–242

    Abstract: Purpose: This study aimed to investigate the recurrence patterns in patients who underwent curative surgery for gastric cancer (GC) and analyze their prognostic value for post-recurrence survival (PRS).: Materials and methods: We retrospectively ... ...

    Abstract Purpose: This study aimed to investigate the recurrence patterns in patients who underwent curative surgery for gastric cancer (GC) and analyze their prognostic value for post-recurrence survival (PRS).
    Materials and methods: We retrospectively reviewed the medical records of 204 patients who experienced GC recurrence following curative gastrectomy for GC at a single institution between January 2012 and December 2017. Specific recurrence patterns (lymph node, peritoneal, and hematogenous) and their multiplicity were analyzed as prognostic factors of PRS.
    Results: The median PRS of the 204 patients was 8.3 months (interquartile range [IQR]: 3.2-17.4). For patients with a single recurrence pattern (n=164), the difference in each recurrence pattern did not show a significant prognostic value for PRS (lymph node vs. peritoneal, P=0.343; peritoneal vs. hematogenous, P=0.660; lymph node vs. hematogenous, P=0.822). However, the patients with a single recurrence pattern had significantly longer PRS than those with multiple recurrence patterns (median PRS: 10.2 months [IQR: 3.7-18.7] vs. 3.9 months [IQR: 1.8-10.4]; P=0.037). In the multivariate analysis, multiple recurrence patterns emerged as independent prognostic factors for poor PRS (hazard ratio, 1.553; 95% confidence interval, 1.092-2.208; P=0.014) along with serosal invasion, recurrence within 1 year after gastrectomy, and the absence of post-recurrence chemotherapy.
    Conclusions: Regardless of the specific recurrence pattern, multiple recurrence patterns emerged as independent prognostic factors for poor PRS compared with a single recurrence pattern.
    Language English
    Publishing date 2024-04-04
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2637180-7
    ISSN 2093-5641 ; 2093-582X
    ISSN (online) 2093-5641
    ISSN 2093-582X
    DOI 10.5230/jgc.2024.24.e18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Efficacy and safety of mineralocorticoid receptor antagonists for the treatment of low-renin hypertension: a systematic review and meta-analysis.

    Shah, Sonali S / Zhang, Jinghong / Gwini, Stella May / Young, Morag J / Fuller, Peter J / Yang, Jun

    Journal of human hypertension

    2024  Volume 38, Issue 5, Page(s) 383–392

    Abstract: Hypertension is the leading risk factor for premature death. The optimal treatment of low-renin hypertension (LRH), present in 30% of hypertensive individuals, is not known. LRH likely reflects a state of excess salt, expanded volume and/or ... ...

    Abstract Hypertension is the leading risk factor for premature death. The optimal treatment of low-renin hypertension (LRH), present in 30% of hypertensive individuals, is not known. LRH likely reflects a state of excess salt, expanded volume and/or mineralocorticoid receptor (MR) activation. Therefore, targeted treatment with MR antagonists (MRA) may be beneficial. The objective of this systematic review was to assess the efficacy of MRA therapy in LRH. MEDLINE, Embase and Cochrane databases were searched for randomised controlled trials of adults with LRH that compared the efficacy of MRA to placebo or other antihypertensive treatments. Risk of bias was assessed using the Cochrane risk of bias tool. A meta-analysis was performed using a random-effects model to estimate the difference in blood pressure and the certainty of evidence was assessed using the GRADE approach. The protocol is registered on PROSPERO (CRD42022318763). From the 1612 records identified, 17 studies met the inclusion criteria with a total sample size of 1043 participants. Seven studies (n = 345) were assessed as having a high risk of bias. Meta-analysis indicated that MRA reduced systolic blood pressure by -6.8 mmHg (95% confidence interval -9.6 to -4.1) and -4.8 mmHg (95% confidence interval -11.9 to 2.4) compared to angiotensin-converting enzyme inhibitors/angiotensin receptor blockers (ACEi/ARB) and diuretics. The certainty of the evidence was assessed as moderate and very low, respectively. The findings of this systematic review suggest that MRA is effective in lowering blood pressure in LRH and may be better than ACEi/ARB. Translation to clinical practice is limited by the uncertainty of evidence.
    MeSH term(s) Humans ; Mineralocorticoid Receptor Antagonists/therapeutic use ; Mineralocorticoid Receptor Antagonists/adverse effects ; Hypertension/drug therapy ; Hypertension/physiopathology ; Treatment Outcome ; Renin/antagonists & inhibitors ; Blood Pressure/drug effects ; Antihypertensive Agents/therapeutic use ; Antihypertensive Agents/adverse effects
    Chemical Substances Mineralocorticoid Receptor Antagonists ; Renin (EC 3.4.23.15) ; Antihypertensive Agents
    Language English
    Publishing date 2024-01-11
    Publishing country England
    Document type Systematic Review ; Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't
    ZDB-ID 639472-3
    ISSN 1476-5527 ; 0950-9240
    ISSN (online) 1476-5527
    ISSN 0950-9240
    DOI 10.1038/s41371-023-00891-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2380: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  8. Article: Correction of pixie ear: infraauricular skin redraping method.

    Kim, Jun Hyeok / Yang, Young Bin / Oh, Deuk Young

    Archives of craniofacial surgery

    2022  Volume 23, Issue 4, Page(s) 187–189

    Abstract: Patients with pixie ear have an attached, tapering, and low-set earlobe. Traditional methods usually describe excision of the caudal portion of the lobule and reattachment in a more superior position. The present report suggests a simplified skin ... ...

    Abstract Patients with pixie ear have an attached, tapering, and low-set earlobe. Traditional methods usually describe excision of the caudal portion of the lobule and reattachment in a more superior position. The present report suggests a simplified skin redraping method for correction of pixie ear. The procedure provides easy method to design and perform, which only requires elevation and trimming of the skin. Other ancillary procedures, such as flap design, anchoring, plication, and subdermal fixation, are not required. This method produces satisfactory results. Postoperative scar is invisible because the incision is on the retroauricular region, and the corrected earlobe has a more natural appearance than the repositioned earlobe. Moreover, skin redraping avoids tension, which contributes to minimization of the postoperative scar.
    Language English
    Publishing date 2022-08-20
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2800630-6
    ISSN 2287-5603 ; 2287-1152
    ISSN (online) 2287-5603
    ISSN 2287-1152
    DOI 10.7181/acfs.2022.00675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Mineralocorticoid receptor signalling in primary aldosteronism.

    Yang, Jun / Young, Morag J / Cole, Timothy J / Fuller, Peter J

    The Journal of endocrinology

    2023  Volume 259, Issue 1

    Abstract: Primary aldosteronism, or Conn syndrome, is the most common endocrine cause of hypertension. It is associated with a higher risk of cardiovascular, metabolic and renal diseases, as well as a lower quality of life than for hypertension due to other causes. ...

    Abstract Primary aldosteronism, or Conn syndrome, is the most common endocrine cause of hypertension. It is associated with a higher risk of cardiovascular, metabolic and renal diseases, as well as a lower quality of life than for hypertension due to other causes. The multi-systemic effects of primary aldosteronism can be attributed to aldosterone-mediated activation of the mineralocorticoid receptor in a range of tissues. In this review, we explore the signalling pathways of the mineralocorticoid receptor, with a shift from the traditional focus on the regulation of renal sodium-potassium exchange to a broader understanding of its role in the modulation of tissue inflammation, fibrosis and remodelling. The appreciation of primary aldosteronism as a multi-system disease with tissue-specific pathophysiology may lead to more vigilant testing and earlier institution of targeted interventions.
    MeSH term(s) Humans ; Hyperaldosteronism/complications ; Receptors, Mineralocorticoid/metabolism ; Quality of Life ; Mineralocorticoid Receptor Antagonists ; Aldosterone/metabolism ; Hypertension/complications
    Chemical Substances Receptors, Mineralocorticoid ; Mineralocorticoid Receptor Antagonists ; Aldosterone (4964P6T9RB)
    Language English
    Publishing date 2023-08-28
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 3028-4
    ISSN 1479-6805 ; 0022-0795
    ISSN (online) 1479-6805
    ISSN 0022-0795
    DOI 10.1530/JOE-22-0249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Uh III Zs.133: Show issues Location:
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  10. Article: Identification and Growth Characteristics of a Gluten-Degrading Bacterium from Wheat Grains for Gluten-Degrading Enzyme Production.

    Lee, Ga-Yang / Jung, Min-Jeong / Kim, Byoung-Mok / Jun, Joon-Young

    Microorganisms

    2023  Volume 11, Issue 12

    Abstract: Immunogenic peptides from wheat gluten can be produced during digestion, which are difficult to digest by gastrointestinal proteases and negatively affect immune responses in humans. Gluten intolerance is a problem in countries where wheat is a staple ... ...

    Abstract Immunogenic peptides from wheat gluten can be produced during digestion, which are difficult to digest by gastrointestinal proteases and negatively affect immune responses in humans. Gluten intolerance is a problem in countries where wheat is a staple food, and a gluten-free diet is commonly recommended for its treatment and prevention. Enzyme approaches for degradation of the peptides can be considered as a strategy for its prevention. Here, we isolated a gluten-degrading bacterium,
    Language English
    Publishing date 2023-11-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720891-6
    ISSN 2076-2607
    ISSN 2076-2607
    DOI 10.3390/microorganisms11122884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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