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  1. Article ; Online: p

    Pal, Sanchari / Das, Debjit / Bhunia, Sabyasachi

    Organic & biomolecular chemistry

    2024  Volume 22, Issue 8, Page(s) 1527–1579

    Abstract: Since the beginning of this century, ...

    Abstract Since the beginning of this century,
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2097583-1
    ISSN 1477-0539 ; 1477-0520
    ISSN (online) 1477-0539
    ISSN 1477-0520
    DOI 10.1039/d3ob01766d
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: P

    Sil, Amrita / Betkerur, Jayadev / Das, Nilay Kanti

    Indian dermatology online journal

    2019  Volume 10, Issue 6, Page(s) 745–750

    Abstract: Biomedical research relies on proving (or disproving) a research hypothesis, ... ...

    Abstract Biomedical research relies on proving (or disproving) a research hypothesis, and
    Language English
    Publishing date 2019-11-01
    Publishing country India
    Document type Journal Article
    ZDB-ID 2585814-2
    ISSN 2249-5673 ; 2229-5178
    ISSN (online) 2249-5673
    ISSN 2229-5178
    DOI 10.4103/idoj.IDOJ_368_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Analysis of the P

    Frankel, Bruce M / Cachia, David / Patel, Sunil J / Das, Arabinda

    Journal of molecular neuroscience : MN

    2021  Volume 71, Issue 8, Page(s) 1714–1722

    Abstract: The P ...

    Abstract The P
    MeSH term(s) Brain Neoplasms/genetics ; Brain Neoplasms/metabolism ; Chromosomes, Human, Pair 22/genetics ; Cloning, Molecular ; Ependymoma/genetics ; Ependymoma/metabolism ; Glioblastoma/genetics ; Glioblastoma/metabolism ; High Mobility Group Proteins/chemistry ; High Mobility Group Proteins/genetics ; High Mobility Group Proteins/metabolism ; Humans ; Protein Domains
    Chemical Substances High Mobility Group Proteins
    Language English
    Publishing date 2021-02-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1043392-2
    ISSN 1559-1166 ; 0895-8696
    ISSN (online) 1559-1166
    ISSN 0895-8696
    DOI 10.1007/s12031-021-01808-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3006: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article: Electroless Ni-P-MoS

    Mohanty, Shalini / Jamal, Naghma / Das, Alok Kumar / Prashanth, Konda Gokuldoss

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 19

    Abstract: The work aimed to produce Ni-P-MoS ...

    Abstract The work aimed to produce Ni-P-MoS
    Language English
    Publishing date 2022-09-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15196806
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Analysis of P

    Frankel, Bruce M / Cachia, David / Patel, Sunil J / Das, Arabinda

    Journal of molecular neuroscience : MN

    2020  Volume 70, Issue 9, Page(s) 1415–1424

    Abstract: ... for these malignancies. The P ...

    Abstract Allelic losses of the q13.3 region of chromosome 19 have been documented in all major types of diffuse gliomas, strongly suggesting the presence of a 19q13.3 tumor suppressor gene responsible for these malignancies. The P
    MeSH term(s) Brain/metabolism ; Brain Neoplasms/genetics ; Brain Neoplasms/pathology ; Cell Membrane/metabolism ; Chromosomes, Human, Pair 19/genetics ; Epithelial Cells/metabolism ; Glioma/genetics ; Glioma/pathology ; Humans ; Mediator Complex/genetics ; Mediator Complex/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism
    Chemical Substances MED25 protein, human ; Mediator Complex ; RNA, Messenger
    Language English
    Publishing date 2020-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1043392-2
    ISSN 1559-1166 ; 0895-8696
    ISSN (online) 1559-1166
    ISSN 0895-8696
    DOI 10.1007/s12031-020-01562-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3006: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  6. Article: The "P"-Value: The Primary Alphabet of Research Revisited.

    Das, Debasish / Das, Tutan

    International journal of preventive medicine

    2023  Volume 14, Page(s) 41

    Abstract: Each research roves around ... ...

    Abstract Each research roves around the
    Language English
    Publishing date 2023-04-26
    Publishing country Iran
    Document type Journal Article
    ZDB-ID 2574680-7
    ISSN 2008-8213 ; 2008-7802
    ISSN (online) 2008-8213
    ISSN 2008-7802
    DOI 10.4103/ijpvm.ijpvm_200_22
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Development of direct compression Acetazolamide tablet with improved bioavailability in healthy human volunteers enabled by cocrystallization with p-Aminobenzoic acid.

    Kumari, Nimmy / Roy, Parag / Roy, Sukanta / Wang, Chenguang / Das, Sourav / Pandey, Noopur / Mondal, Susanta Kumar / Bose, Anirbandeep / Sun, Changquan Calvin / Ghosh, Animesh

    International journal of pharmaceutics

    2024  Volume 652, Page(s) 123793

    Abstract: ... of acetazolamide (ACZ), using a 1:1 cocrystal of acetazolamide with p-aminobenzoic acid (ACZ-PABA). The ACZ-PABA ...

    Abstract Pharmaceutical cocrystallization has been widely used to improve physicochemical properties of APIs. However, developing cocrystal formulation with proven clinical success remains scarce. Successful translation of a cocrystal to suitable dosage forms requires simultaneously improvement of several deficient physicochemical properties over the parent API, without deteriorating other properties critical for successful product development. In the present work, we report the successful development of a direct compression tablet product of acetazolamide (ACZ), using a 1:1 cocrystal of acetazolamide with p-aminobenzoic acid (ACZ-PABA). The ACZ-PABA tablet exhibits superior biopharmaceutical performance against the commercial tablet, DIAMOX® (250 mg), in healthy human volunteers, leading to more than 50 % reduction in the required dose.
    MeSH term(s) Humans ; Acetazolamide/chemistry ; 4-Aminobenzoic Acid/chemistry ; Crystallization ; Biological Availability ; Healthy Volunteers ; Solubility ; Tablets/chemistry
    Chemical Substances Acetazolamide (O3FX965V0I) ; 4-Aminobenzoic Acid (TL2TJE8QTX) ; Tablets
    Language English
    Publishing date 2024-01-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 428962-6
    ISSN 1873-3476 ; 0378-5173
    ISSN (online) 1873-3476
    ISSN 0378-5173
    DOI 10.1016/j.ijpharm.2024.123793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1409: Show issues Location:
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  8. Article ; Online: Experimental Evidence for an Attractive p-ϕ Interaction.

    Acharya, S / Adamová, D / Adler, A / Adolfsson, J / Aglieri Rinella, G / Agnello, M / Agrawal, N / Ahammed, Z / Ahmad, S / Ahn, S U / Ahuja, I / Akbar, Z / Akindinov, A / Al-Turany, M / Alam, S N / Aleksandrov, D / Alessandro, B / Alfanda, H M / Alfaro Molina, R /
    Ali, B / Ali, Y / Alici, A / Alizadehvandchali, N / Alkin, A / Alme, J / Alt, T / Altenkamper, L / Altsybeev, I / Anaam, M N / Andrei, C / Andreou, D / Andronic, A / Angeletti, M / Anguelov, V / Antinori, F / Antonioli, P / Anuj, C / Apadula, N / Aphecetche, L / Appelshäuser, H / Arcelli, S / Arnaldi, R / Arsene, I C / Arslandok, M / Augustinus, A / Averbeck, R / Aziz, S / Azmi, M D / Badalà, A / Baek, Y W / Bai, X / Bailhache, R / Bailung, Y / Bala, R / Balbino, A / Baldisseri, A / Balis, B / Ball, M / Banerjee, D / Barbera, R / Barioglio, L / Barlou, M / Barnaföldi, G G / Barnby, L S / Barret, V / Bartels, C / Barth, K / Bartsch, E / Baruffaldi, F / Bastid, N / Basu, S / Batigne, G / Batyunya, B / Bauri, D / Bazo Alba, J L / Bearden, I G / Beattie, C / Belikov, I / Bell Hechavarria, A D C / Bellini, F / Bellwied, R / Belokurova, S / Belyaev, V / Bencedi, G / Beole, S / Bercuci, A / Berdnikov, Y / Berdnikova, A / Berenyi, D / Bergmann, L / Besoiu, M G / Betev, L / Bhaduri, P P / Bhasin, A / Bhat, I R / Bhat, M A / Bhattacharjee, B / Bhattacharya, P / Bianchi, L / Bianchi, N / Bielčík, J / Bielčíková, J / Biernat, J / Bilandzic, A / Biro, G / Biswas, S / Blair, J T / Blau, D / Blidaru, M B / Blume, C / Boca, G / Bock, F / Bogdanov, A / Boi, S / Bok, J / Boldizsár, L / Bolozdynya, A / Bombara, M / Bond, P M / Bonomi, G / Borel, H / Borissov, A / Bossi, H / Botta, E / Bratrud, L / Braun-Munzinger, P / Bregant, M / Broz, M / Bruno, G E / Buckland, M D / Budnikov, D / Buesching, H / Bufalino, S / Bugnon, O / Buhler, P / Buthelezi, Z / Butt, J B / Bysiak, S A / Caffarri, D / Cai, M / Caines, H / Caliva, A / Calvo Villar, E / Camacho, J M M / Camacho, R S / Camerini, P / Canedo, F D M / Carnesecchi, F / Caron, R / Castillo Castellanos, J / Casula, E A R / Catalano, F / Ceballos Sanchez, C / Chakraborty, P / Chandra, S / Chapeland, S / Chartier, M / Chattopadhyay, S / Chauvin, A / Chavez, T G / Cheshkov, C / Cheynis, B / Chibante Barroso, V / Chinellato, D D / Chizzali, E S / Cho, S / Chochula, P / Christakoglou, P / Christensen, C H / Christiansen, P / Chujo, T / Cicalo, C / Cifarelli, L / Cindolo, F / Ciupek, M R / Clai, G / Cleymans, J / Colamaria, F / Colburn, J S / Colella, D / Collu, A / Colocci, M / Concas, M / Conesa Balbastre, G / Conesa Del Valle, Z / Contin, G / Contreras, J G / Coquet, M L / Cormier, T M / Cortese, P / Cosentino, M R / Costa, F / Costanza, S / Crochet, P / Cuautle, E / Cui, P / Cunqueiro, L / Dainese, A / Damas, F P A / Danisch, M C / Danu, A / Das, I / Das, P / Das, P / Das, S / Dash, S / De, S / De Caro, A / de Cataldo, G / De Cilladi, L / de Cuveland, J / De Falco, A / De Gruttola, D / De Marco, N / De Martin, C / De Pasquale, S / Deb, S / Degenhardt, H F / Deja, K R / Del Grande, R / Dello Stritto, L / Delsanto, S / Deng, W / Dhankher, P / Di Bari, D / Di Mauro, A / Diaz, R A / Dietel, T / Ding, Y / Divià, R / Dixit, D U / Djuvsland, Ø / Dmitrieva, U / Do, J / Dobrin, A / Dönigus, B / Dordic, O / Dubey, A K / Dubla, A / Dudi, S / Dukhishyam, M / Dupieux, P / Dzalaiova, N / Eder, T M / Ehlers, R J / Eikeland, V N / Eisenhut, F / Elia, D / Erazmus, B / Ercolessi, F / Erhardt, F / Erokhin, A / Ersdal, M R / Espagnon, B / Eulisse, G / Evans, D / Evdokimov, S / Fabbietti, L / Faggin, M / Faivre, J / Fan, F / Fantoni, A / Fasel, M / Fecchio, P / Feliciello, A / Feofilov, G / Fernández Téllez, A / Ferrero, A / Ferretti, A / Feuillard, V J G / Figiel, J / Filchagin, S / Finogeev, D / Fionda, F M / Fiorenza, G / Flor, F / Flores, A N / Foertsch, S / Foka, P / Fokin, S / Fragiacomo, E / Frajna, E / Fuchs, U / Funicello, N / Furget, C / Furs, A / Gaardhøje, J J / Gagliardi, M / Gago, A M / Gal, A / Galvan, C D / Ganoti, P / Garabatos, C / Garcia, J R A / Garcia-Solis, E / Garg, K / Gargiulo, C / Garibli, A / Garner, K / Gasik, P / Gauger, E F / Gautam, A / Gay Ducati, M B / Germain, M / Ghosh, J / Ghosh, P / Ghosh, S K / Giacalone, M / Gianotti, P / Giubellino, P / Giubilato, P / Glaenzer, A M C / Glässel, P / Goh, D J Q / Gonzalez, V / González-Trueba, L H / Gorbunov, S / Gorgon, M / Görlich, L / Gotovac, S / Grabski, V / Graczykowski, L K / Greiner, L / Grelli, A / Grigoras, C / Grigoriev, V / Grigoryan, A / Grigoryan, S / Groettvik, O S / Grosa, F / Grosse-Oetringhaus, J F / Grosso, R / Guardiano, G G / Guernane, R / Guilbaud, M / Gulbrandsen, K / Gunji, T / Gupta, A / Gupta, R / Guzman, I B / Guzman, S P / Gyulai, L / Habib, M K / Hadjidakis, C / Halimoglu, G / Hamagaki, H / Hamar, G / Hamid, M / Hannigan, R / Haque, M R / Harlenderova, A / Harris, J W / Harton, A / Hasenbichler, J A / Hassan, H / Hatzifotiadou, D / Hauer, P / Havener, L B / Hayashi, S / Heckel, S T / Hellbär, E / Helstrup, H / Herman, T / Hernandez, E G / Herrera Corral, G / Herrmann, F / Hetland, K F / Hillemanns, H / Hills, C / Hippolyte, B / Hofman, B / Hohlweger, B / Honermann, J / Hong, G H / Horak, D / Hornung, S / Horzyk, A / Hosokawa, R / Hristov, P / Huang, C / Hughes, C / Huhn, P / Humanic, T J / Hushnud, H / Husova, L A / Hutson, A / Hutter, D / Iddon, J P / Ilkaev, R / Ilyas, H / Inaba, M / Innocenti, G M / Ippolitov, M / Isakov, A / Islam, M S / Ivanov, M / Ivanov, V / Izucheev, V / Jablonski, M / Jacak, B / Jacazio, N / Jacobs, P M / Jadlovska, S / Jadlovsky, J / Jaelani, S / Jahnke, C / Jakubowska, M J / Janik, M A / Janson, T / Jercic, M / Jevons, O / Jonas, F / Jones, P G / Jowett, J M / Jung, J / Jung, M / Junique, A / Jusko, A / Kaewjai, J / Kalinak, P / Kalweit, A / Kaplin, V / Kar, S / Karasu Uysal, A / Karatovic, D / Karavichev, O / Karavicheva, T / Karczmarczyk, P / Karpechev, E / Kazantsev, A / Kebschull, U / Keidel, R / Keijdener, D L D / Keil, M / Ketzer, B / Khabanova, Z / Khan, A M / Khan, S / Khanzadeev, A / Kharlov, Y / Khatun, A / Khuntia, A / Kileng, B / Kim, B / Kim, D / Kim, D J / Kim, E J / Kim, J / Kim, J S / Kim, M / Kim, S / Kim, T / Kirsch, S / Kisel, I / Kiselev, S / Kisiel, A / Kitowski, J P / Klay, J L / Klein, J / Klein, S / Klein-Bösing, C / Kleiner, M / Klemenz, T / Kluge, A / Knospe, A G / Kobdaj, C / Köhler, M K / Kollegger, T / Kondratyev, A / Kondratyeva, N / Kondratyuk, E / Konig, J / Konigstorfer, S A / Konopka, P J / Kornakov, G / Koryciak, S D / Koska, L / Kotliarov, A / Kovalenko, O / Kovalenko, V / Kowalski, M / Králik, I / Kravčáková, A / Kreis, L / Krivda, M / Krizek, F / Krizkova Gajdosova, K / Kroesen, M / Krüger, M / Kryshen, E / Krzewicki, M / Kučera, V / Kuhn, C / Kuijer, P G / Kumaoka, T / Kumar, D / Kumar, L / Kumar, N / Kundu, S / Kurashvili, P / Kurepin, A / Kurepin, A B / Kuryakin, A / Kushpil, S / Kvapil, J / Kweon, M J / Kwon, J Y / Kwon, Y / La Pointe, S L / La Rocca, P / Lai, Y S / Lakrathok, A / Lamanna, M / Langoy, R / Lapidus, K / Larionov, P / Laudi, E / Lautner, L / Lavicka, R / Lazareva, T / Lea, R / Lee, J / Lehrbach, J / Lemmon, R C / León Monzón, I / Lesser, E D / Lettrich, M / Lévai, P / Li, X / Li, X L / Lien, J / Lietava, R / Lim, B / Lim, S H / Lindenstruth, V / Lindner, A / Lippmann, C / Liu, A / Liu, J / Lofnes, I M / Loginov, V / Loizides, C / Loncar, P / Lopez, J A / Lopez, X / López Torres, E / Luhder, J R / Lunardon, M / Luparello, G / Ma, Y G / Maevskaya, A / Mager, M / Mahmoud, T / Maire, A / Malaev, M / Malik, Q W / Malinina, L / Mal'Kevich, D / Mallick, N / Malzacher, P / Mandaglio, G / Manko, V / Manso, F / Manzari, V / Mao, Y / Mareš, J / Margagliotti, G V / Margotti, A / Marín, A / Markert, C / Marquard, M / Martin, N A / Martinengo, P / Martinez, J L / Martínez, M I / Martínez García, G / Masciocchi, S / Masera, M / Masoni, A / Massacrier, L / Mastroserio, A / Mathis, A M / Matonoha, O / Matuoka, P F T / Matyja, A / Mayer, C / Mazuecos, A L / Mazzaschi, F / Mazzilli, M / Mazzoni, M A / Mdhluli, J E / Mechler, A F / Meddi, F / Melikyan, Y / Menchaca-Rocha, A / Meninno, E / Menon, A S / Meres, M / Mhlanga, S / Miake, Y / Micheletti, L / Migliorin, L C / Mihaylov, D L / Mikhaylov, K / Mishra, A N / Miśkowiec, D / Modak, A / Mohanty, A P / Mohanty, B / Mohisin Khan, M / Moravcova, Z / Mordasini, C / Moreira De Godoy, D A / Moreno, L A P / Morozov, I / Morsch, A / Mrnjavac, T / Muccifora, V / Mudnic, E / Mühlheim, D / Muhuri, S / Mulligan, J D / Mulliri, A / Munhoz, M G / Munzer, R H / Murakami, H / Murray, S / Musa, L / Musinsky, J / Myers, C J / Myrcha, J W / Naik, B / Nair, R / Nandi, B K / Nania, R / Nappi, E / Naru, M U / Nassirpour, A F / Nath, A / Nattrass, C / Neagu, A / Nellen, L / Nesbo, S V / Neskovic, G / Nesterov, D / Nielsen, B S / Nikolaev, S / Nikulin, S / Nikulin, V / Noferini, F / Noh, S / Nomokonov, P / Norman, J / Novitzky, N / Nowakowski, P / Nyanin, A / Nystrand, J / Ogino, M / Ohlson, A / Okorokov, V A / Oleniacz, J / Oliveira Da Silva, A C / Oliver, M H / Onnerstad, A / Oppedisano, C / Ortiz Velasquez, A / Osako, T / Oskarsson, A / Otwinowski, J / Oyama, K / Pachmayer, Y / Padhan, S / Pagano, D / Paić, G / Palasciano, A / Pan, J / Panebianco, S / Pareek, P / Park, J / Parkkila, J E / Pathak, S P / Patra, R N / Paul, B / Pazzini, J / Pei, H / Peitzmann, T / Peng, X / Pereira, L G / Pereira Da Costa, H / Peresunko, D / Perez, G M / Perrin, S / Pestov, Y / Petráček, V / Petrovici, M / Pezzi, R P / Piano, S / Pikna, M / Pillot, P / Pinazza, O / Pinsky, L / Pinto, C / Pisano, S / Płoskoń, M / Planinic, M / Pliquett, F / Poghosyan, M G / Polichtchouk, B / Politano, S / Poljak, N / Pop, A / Porteboeuf-Houssais, S / Porter, J / Pozdniakov, V / Prasad, S K / Preghenella, R / Prino, F / Pruneau, C A / Pshenichnov, I / Puccio, M / Qiu, S / Quaglia, L / Quishpe, R E / Ragoni, S / Rakotozafindrabe, A / Ramello, L / Rami, F / Ramirez, S A R / Ramos, A G T / Rancien, T A / Raniwala, R / Raniwala, S / Räsänen, S S / Rath, R / Ravasenga, I / Read, K F / Redelbach, A R / Redlich, K / Rehman, A / Reichelt, P / Reidt, F / Reme-Ness, H A / Renfordt, R / Rescakova, Z / Reygers, K / Riabov, A / Riabov, V / Richert, T / Richter, M / Riegler, W / Riggi, F / Ristea, C / Rode, S P / Rodríguez Cahuantzi, M / Røed, K / Rogalev, R / Rogochaya, E / Rogoschinski, T S / Rohr, D / Röhrich, D / Rojas, P F / Rokita, P S / Ronchetti, F / Rosano, A / Rosas, E D / Rossi, A / Rotondi, A / Roy, A / Roy, P / Roy, S / Rubini, N / Rueda, O V / Rui, R / Rumyantsev, B / Russek, P G / Rustamov, A / Ryabinkin, E / Ryabov, Y / Rybicki, A / Rytkonen, H / Rzesa, W / Saarimaki, O A M / Sadek, R / Sadovsky, S / Saetre, J / Šafařík, K / Saha, S K / Saha, S / Sahoo, B / Sahoo, P / Sahoo, R / Sahoo, S / Sahu, D / Sahu, P K / Saini, J / Sakai, S / Sambyal, S / Samsonov, V / Sarkar, D / Sarkar, N / Sarma, P / Sarti, V M / Sas, M H P / Schambach, J / Scheid, H S / Schiaua, C / Schicker, R / Schmah, A / Schmidt, C / Schmidt, H R / Schmidt, M O / Schmidt, M / Schmidt, N V / Schmier, A R / Schotter, R / Schukraft, J / Schutz, Y / Schwarz, K / Schweda, K / Scioli, G / Scomparin, E / Seger, J E / Sekiguchi, Y / Sekihata, D / Selyuzhenkov, I / Senyukov, S / Seo, J J / Serebryakov, D / Šerkšnytė, L / Sevcenco, A / Shaba, T J 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    Physical review letters

    2021  Volume 127, Issue 17, Page(s) 172301

    Abstract: ... a proton and a ϕ meson. The result is obtained from two-particle correlations of combined p-ϕ⊕ p[over ¯]-ϕ ... The spin-averaged scattering length and effective range of the p-ϕ interaction are extracted from the fully ... role for the p-ϕ interaction. These data demonstrate that the interaction is dominated by elastic p-ϕ ...

    Abstract This Letter presents the first experimental evidence of the attractive strong interaction between a proton and a ϕ meson. The result is obtained from two-particle correlations of combined p-ϕ⊕ p[over ¯]-ϕ pairs measured in high-multiplicity pp collisions at sqrt[s]=13  TeV by the ALICE Collaboration. The spin-averaged scattering length and effective range of the p-ϕ interaction are extracted from the fully corrected correlation function employing the Lednický-Lyuboshits approach. In particular, the imaginary part of the scattering length vanishes within uncertainties, indicating that inelastic processes do not play a prominent role for the p-ϕ interaction. These data demonstrate that the interaction is dominated by elastic p-ϕ scattering. Furthermore, an analysis employing phenomenological Gaussian- and Yukawa-type potentials is conducted. Under the assumption of the latter, the N-ϕ coupling constant is found to be g_{N-ϕ}=0.14±0.03(stat)±0.02(syst). This work provides valuable experimental input to accomplish a self-consistent description of the N-ϕ interaction, which is particularly relevant for the more fundamental studies on partial restoration of chiral symmetry in nuclear medium.
    Language English
    Publishing date 2021-11-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.127.172301
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  9. Article ; Online: Biosorption of p-chloro meta xylenol (PCMX) by bacterium-encapsulated calcium alginate beads in a novel plug flow process.

    Brahma, Bhanupriya / Das, Megha / Sarkar, Priyabrata / Sarkar, Ujjaini

    Journal of environmental management

    2023  Volume 337, Page(s) 117764

    Abstract: P-Chloro-Meta-Xylenol (PCMX) is a widely used disinfectant. In the current pandemic scenario ...

    Abstract P-Chloro-Meta-Xylenol (PCMX) is a widely used disinfectant. In the current pandemic scenario, its consumption has increased largely, and as a result, wastewater is loaded heavily with PCMX as a contaminant. Remediation of this ecologically toxic phenolic compound is therefore a burning issue. This study proposes an eco-friendly biosorption-based remediation technique to remove PCMX. A novel isolated phenol-resistant gram-negative bacterium, Pandoraea sp. strain BT102, is first encapsulated in biopolymeric calcium alginate beads. These beads are packed in a long adsorption tube and the contaminated water was passed through this packed tube resembling a plug flow reactor. This unique plug-flow set-up is capable of reducing PCMX concentration from 100 mg L
    MeSH term(s) Alginates/chemistry ; Spectroscopy, Fourier Transform Infrared ; Phenols/analysis ; Bacteria ; Adsorption ; Kinetics ; Hydrogen-Ion Concentration ; Water Pollutants, Chemical/chemistry
    Chemical Substances 3,5-xylenol (ONA760G0WA) ; chloroxylenol (0F32U78V2Q) ; Alginates ; Phenols ; Water Pollutants, Chemical
    Language English
    Publishing date 2023-03-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2023.117764
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  10. Article ; Online: Sliding of HIV-1 reverse transcriptase over DNA creates a transient P pocket - targeting P-pocket by fragment screening.

    Singh, Abhimanyu K / Martinez, Sergio E / Gu, Weijie / Nguyen, Hoai / Schols, Dominique / Herdewijn, Piet / De Jonghe, Steven / Das, Kalyan

    Nature communications

    2021  Volume 12, Issue 1, Page(s) 7127

    Abstract: ... the primer 3'-end of a dsDNA substrate and created a transient P-pocket at the priming site. We performed ... that bind the P-pocket, which is composed of structural elements from polymerase active site, primer grip ... the transient P-pocket in solution, and structures of the RT/DNA complex were determined in the presence ...

    Abstract HIV-1 reverse transcriptase (RT) slides over an RNA/DNA or dsDNA substrate while copying the viral RNA to a proviral DNA. We report a crystal structure of RT/dsDNA complex in which RT overstepped the primer 3'-end of a dsDNA substrate and created a transient P-pocket at the priming site. We performed a high-throughput screening of 300 drug-like fragments by X-ray crystallography that identifies two leads that bind the P-pocket, which is composed of structural elements from polymerase active site, primer grip, and template-primer that are resilient to drug-resistance mutations. Analogs of a fragment were synthesized, two of which show noticeable RT inhibition. An engineered RT/DNA aptamer complex could trap the transient P-pocket in solution, and structures of the RT/DNA complex were determined in the presence of an inhibitory fragment. A synthesized analog bound at P-pocket is further analyzed by single-particle cryo-EM. Identification of the P-pocket within HIV RT and the developed structure-based platform provide an opportunity for the design new types of polymerase inhibitors.
    MeSH term(s) Binding Sites ; Cryoelectron Microscopy ; Crystallography, X-Ray ; DNA/chemistry ; Drug Design ; Drug Evaluation, Preclinical ; HIV Reverse Transcriptase/chemistry ; HIV Reverse Transcriptase/drug effects ; HIV Reverse Transcriptase/metabolism ; HIV-1/genetics ; Models, Molecular ; Protein Conformation ; RNA ; Reverse Transcriptase Inhibitors/chemistry ; Reverse Transcriptase Inhibitors/pharmacology
    Chemical Substances Reverse Transcriptase Inhibitors ; RNA (63231-63-0) ; DNA (9007-49-2) ; reverse transcriptase, Human immunodeficiency virus 1 (EC 2.7.7.-) ; HIV Reverse Transcriptase (EC 2.7.7.49)
    Language English
    Publishing date 2021-12-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-021-27409-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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