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Article ; Online: Cervicofacial subcutaneous emphysema and pneumomediastinum after retinal detachment surgery: just another monitored anesthesia eye case.

Colson, James D

2011 Volume 23, Issue 5, Page(s) 410–413

Abstract: Repair of a retinal detachment was performed during a retrobulbar block with monitored anesthesia care and intravenous conscious sedation. Following the procedure and after removal of the sterile drapes, the patient exhibited significant swelling of the ... ...

Abstract	Repair of a retinal detachment was performed during a retrobulbar block with monitored anesthesia care and intravenous conscious sedation. Following the procedure and after removal of the sterile drapes, the patient exhibited significant swelling of the bilateral orbits, face, neck, and chest. Subcutaneous emphysema and pneumomediastinum were confirmed on postoperative chest radiographs and computed tomographic scans. Possible mechanisms and potential sequelae of this intraoperative event are discussed.
MeSH term(s)	Anesthesia/methods ; Conscious Sedation/methods ; Female ; Humans ; Intraoperative Complications ; Mediastinal Emphysema/etiology ; Middle Aged ; Nerve Block/methods ; Retinal Detachment/surgery ; Subcutaneous Emphysema/etiology ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2011-08
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	1011618-7
ISSN	1873-4529 ; 0952-8180
ISSN (online)	1873-4529
ISSN	0952-8180
DOI	10.1016/j.jclinane.2010.08.019
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Article ; Online: Emergency Medical Services Clinicians' Perspectives on Pediatric Non-Transport.

Ward, Caleb E / Singletary, Judith / Hatcliffe, Rachel E / Colson, Cindy D / Simpson, Joelle N / Brown, Kathleen M / Chamberlain, James M

Prehospital emergency care

2022 Volume 27, Issue 8, Page(s) 993–1003

Abstract: Objectives: Emergency medical services clinicians do not transport one-third of all children assessed, even without official pediatric non-transport protocols. Little is known about how EMS clinicians and caregivers decide not to transport a child. Our ... ...

Abstract	Objectives: Emergency medical services clinicians do not transport one-third of all children assessed, even without official pediatric non-transport protocols. Little is known about how EMS clinicians and caregivers decide not to transport a child. Our objectives were to describe how EMS clinicians currently decide whether or not to transport a child and identify barriers to and enablers of successfully implementing an EMS clinician-initiated pediatric non-transport protocol. Methods: We conducted six virtual focus groups with EMS clinicians from the mid-Atlantic. A PhD trained facilitator moderated all groups using a semi-structured moderator guide. Multiple investigators independently coded a deidentified sample transcript. One team member then completed axial coding of the remaining transcripts. Thematic saturation was achieved. Clusters of similar codes were grouped into themes by consensus. Results: We recruited 50 participants, of whom 70% were paramedics and 28% emergency medical technicians. There was agreement that caregivers often use 9-1-1 for low acuity complaints. Participants stated that non-transport usually occurs after shared decision-making between EMS clinicians and caregivers; EMS clinicians advise whether transport is necessary, but caregivers are responsible for making the final decision and signing refusal documentation. Subthemes for how non-transport decisions were made included the presence of agency protocols, caregiver preferences, absence of a guardian on the scene, EMS clinician variability, and distance to the nearest ED. Participants identified the following features that would enable successful implementation of an EMS clinician-initiated non-transport process: a user-friendly interface, clear protocol endpoints, the inclusion of vital sign parameters, resources to leave with caregivers, and optional direct medical oversight. Conclusions: EMS clinicians in our study agreed that non-transport is currently a caregiver decision, but noted a collaborative process of shared decision-making where EMS clinicians advise caregivers whether transport is indicated. Further research is needed to understand the safety of this practice. This study suggests there may be a need for EMS-initiated alternative disposition/non-transport protocols.
MeSH term(s)	Child ; Humans ; Emergency Medical Services ; Emergency Medical Technicians ; Focus Groups ; Paramedics ; Consensus
Language	English
Publishing date	2022-08-29
Publishing country	England
Document type	Journal Article
ZDB-ID	1461751-1
ISSN	1545-0066 ; 1090-3127
ISSN (online)	1545-0066
ISSN	1090-3127
DOI	10.1080/10903127.2022.2108180
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Zs.A 4762: Show issues

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Article ; Online: The

de Vos, Asha / Aluwihare, Lihini / Youngs, Sarah / DiBenedetto, Michelle H / Ward, Collin P / Michel, Anna P M / Colson, Beckett C / Mazzotta, Michael G / Walsh, Anna N / Nelson, Robert K / Reddy, Christopher M / James, Bryan D

ACS environmental Au

2021 Volume 2, Issue 2, Page(s) 128–135

Abstract: In May 2021, ... ...

Abstract	In May 2021, the
Language	English
Publishing date	2021-11-29
Publishing country	United States
Document type	Journal Article
ISSN	2694-2518
ISSN (online)	2694-2518
DOI	10.1021/acsenvironau.1c00031
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Article: The pharmacology of sedation.

Colson, James D

Pain physician

2005 Volume 8, Issue 3, Page(s) 297–308

Abstract: Sedation is commonly provided for patients undergoing interventional pain management procedures. Although many pain management interventionalists have trained in anesthesiology, the use of sedatives, analgesics and hypnotics, as well as monitoring ... ...

Abstract	Sedation is commonly provided for patients undergoing interventional pain management procedures. Although many pain management interventionalists have trained in anesthesiology, the use of sedatives, analgesics and hypnotics, as well as monitoring techniques, may vary considerably between practices. This review provides an update on recent advances in the pharmacology of drugs commonly used for sedation, anxiolysis and analgesia. The information should also be useful for non-anesthesiologists who provide sedation for their patients. In addition to providing the right drug for the procedure, patient monitoring must be appropriate for the patient and the clinical circumstances. Undertaking a sedation analgesic course of therapy in support of an interventional procedure will require that patients are monitored appropriately during the course of treatment. Guidelines for monitoring patients during sedation are available.
Language	English
Publishing date	2005-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	2146393-1
ISSN	1533-3159
ISSN	1533-3159
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Article ; Online: A Pilot Study Using Machine Learning Algorithms and Wearable Technology for the Early Detection of Postoperative Complications After Cardiothoracic Surgery.

Beqari, Jorind / Powell, Joseph / Hurd, Jacob / Potter, Alexandra L / McCarthy, Meghan / Srinivasan, Deepti / Wang, Danny / Cranor, James / Zhang, Lizi / Webster, Kyle / Kim, Joshua / Rosenstein, Allison / Zheng, Zeyuan / Lin, Tung Ho / Li, Jing / Fang, Zhengyu / Zhang, Yuhang / Anderson, Alex / Madsen, James /

Annals of surgery

2024

Abstract: Objective: To evaluate whether a machine learning algorithm (i.e. the "NightSignal" algorithm) can be used for the detection of postoperative complications prior to symptom onset after cardiothoracic surgery.: Summary background data: Methods that ... ...

Abstract	Objective: To evaluate whether a machine learning algorithm (i.e. the "NightSignal" algorithm) can be used for the detection of postoperative complications prior to symptom onset after cardiothoracic surgery. Summary background data: Methods that enable the early detection of postoperative complications after cardiothoracic surgery are needed. Methods: This was a prospective observational cohort study conducted from July 2021 to February 2023 at a single academic tertiary care hospital. Patients aged 18 years or older scheduled to undergo cardiothoracic surgery were recruited. Study participants wore a Fitbit watch continuously for at least 1 week preoperatively and up to 90-days postoperatively. The ability of the NightSignal algorithm-which was previously developed for the early detection of Covid-19-to detect postoperative complications was evaluated. The primary outcomes were algorithm sensitivity and specificity for postoperative event detection. Results: A total of 56 patients undergoing cardiothoracic surgery met inclusion criteria, of which 24 (42.9%) underwent thoracic operations and 32 (57.1%) underwent cardiac operations. The median age was 62 (IQR: 51-68) years and 30 (53.6%) patients were female. The NightSignal algorithm detected 17 of the 21 postoperative events a median of 2 (IQR: 1-3) days prior to symptom onset, representing a sensitivity of 81%. The specificity, negative predictive value, and positive predictive value of the algorithm for the detection of postoperative events were 75%, 97%, and 28%, respectively. Conclusions: Machine learning analysis of biometric data collected from wearable devices has the potential to detect postoperative complications-prior to symptom onset-after cardiothoracic surgery.
Language	English
Publishing date	2024-03-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	340-2
ISSN	1528-1140 ; 0003-4932
ISSN (online)	1528-1140
ISSN	0003-4932
DOI	10.1097/SLA.0000000000006263
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Article: St. Matthew Island colonized through multiple long-distance red fox (Vulpesvulpes) dispersal events

Colson, K.E / James D. Smith / Kris J. Hundertmark

Canadian journal of zoology. 2017 June 7, v. 95, no. 8

2017

Abstract: Expansion of red fox (Vulpes vulpes (L., 1758)) into new arctic habitat and the potential for competition with arctic fox (Vulpes lagopus (L., 1758)) are of considerable conservation concern. Previous work has focused on red fox expanding into contiguous ...

Abstract	Expansion of red fox (Vulpes vulpes (L., 1758)) into new arctic habitat and the potential for competition with arctic fox (Vulpes lagopus (L., 1758)) are of considerable conservation concern. Previous work has focused on red fox expanding into contiguous areas with few barriers to dispersal. Here, we examine mitochondrial DNA in red fox on recently colonized St. Matthew Island in the Bering Sea to determine their ultimate origin. Though limited in sample size (n = 7), we found that St. Matthew Island was colonized by North American lineages; surprisingly, despite the >400 km distance to the mainland, we found the island was colonized by at least three mitochondrial matrilines. These results suggest that even extremely isolated places may be colonized by red fox, and that the over-ice or over-ocean dispersal ability of red fox may have been previously underappreciated.
Keywords	Vulpes lagopus ; Vulpes vulpes ; habitats ; mitochondria ; mitochondrial DNA ; Arctic region ; Bering Sea
Language	English
Dates of publication	2017-0607
Size	p. 607-609.
Publishing place	NRC Research Press
Document type	Article
ZDB-ID	241716-9
ISSN	1480-3283 ; 0008-4301
ISSN (online)	1480-3283
ISSN	0008-4301
DOI	10.1139/cjz-2016-0289
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Racial and Ethnic Differences in Internal Medicine Residency Assessments.

Boatright, Dowin / Anderson, Nientara / Kim, Jung G / Holmboe, Eric S / McDade, William A / Fancher, Tonya / Gross, Cary P / Chaudhry, Sarwat / Nguyen, Mytien / Nguemeni Tiako, Max Jordan / Colson, Eve / Xu, Yunshan / Li, Fangyong / Dziura, James D / Saha, Somnath

JAMA network open

2022 Volume 5, Issue 12, Page(s) e2247649

Abstract: Importance: Previous studies have demonstrated racial and ethnic inequities in medical student assessments, awards, and faculty promotions at academic medical centers. Few data exist about similar racial and ethnic disparities at the level of graduate ... ...

Abstract	Importance: Previous studies have demonstrated racial and ethnic inequities in medical student assessments, awards, and faculty promotions at academic medical centers. Few data exist about similar racial and ethnic disparities at the level of graduate medical education. Objective: To examine the association between race and ethnicity and performance assessments among a national cohort of internal medicine residents. Design, setting, and participants: This retrospective cohort study evaluated assessments of performance for 9026 internal medicine residents from the graduating classes of 2016 and 2017 at Accreditation Council of Graduate Medical Education (ACGME)-accredited internal medicine residency programs in the US. Analyses were conducted between July 1, 2020, and June 31, 2022. Main outcomes and measures: The primary outcome was midyear and year-end total ACGME Milestone scores for underrepresented in medicine (URiM [Hispanic only; non-Hispanic American Indian, Alaska Native, or Native Hawaiian/Pacific Islander only; or non-Hispanic Black/African American]) and Asian residents compared with White residents as determined by their Clinical Competency Committees and residency program directors. Differences in scores between Asian and URiM residents compared with White residents were also compared for each of the 6 competency domains as supportive outcomes. Results: The study cohort included 9026 residents from 305 internal medicine residency programs. Of these residents, 3994 (44.2%) were female, 3258 (36.1%) were Asian, 1216 (13.5%) were URiM, and 4552 (50.4%) were White. In the fully adjusted model, no difference was found in the initial midyear total Milestone scores between URiM and White residents, but there was a difference between Asian and White residents, which favored White residents (mean [SD] difference in scores for Asian residents: -1.27 [0.38]; P < .001). In the second year of training, White residents received increasingly higher scores relative to URiM and Asian residents. These racial disparities peaked in postgraduate year (PGY) 2 (mean [SD] difference in scores for URiM residents, -2.54 [0.38]; P < .001; mean [SD] difference in scores for Asian residents, -1.9 [0.27]; P < .001). By the final year 3 assessment, the gap between White and Asian and URiM residents' scores narrowed, and no racial or ethnic differences were found. Trends in racial and ethnic differences among the 6 competency domains mirrored total Milestone scores, with differences peaking in PGY2 and then decreasing in PGY3 such that parity in assessment was reached in all competency domains by the end of training. Conclusions and relevance: In this cohort study, URiM and Asian internal medicine residents received lower ratings on performance assessments than their White peers during the first and second years of training, which may reflect racial bias in assessment. This disparity in assessment may limit opportunities for physicians from minoritized racial and ethnic groups and hinder physician workforce diversity.
MeSH term(s)	Humans ; Female ; Male ; Internship and Residency ; Cohort Studies ; Retrospective Studies ; Education, Medical, Graduate ; Ethnicity
Language	English
Publishing date	2022-12-01
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ISSN	2574-3805
ISSN (online)	2574-3805
DOI	10.1001/jamanetworkopen.2022.47649
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Article ; Online: Cumulative effects of municipal effluent and parasite infection in yellow perch: A field study using high-throughput RNA-sequencing.

Lacaze, Émilie / Gendron, Andrée D / Miller, Jason L / Colson, Tash-Lynn L / Sherry, James P / Giraudo, Maeva / Marcogliese, David J / Houde, Magali

The Science of the total environment

2019 Volume 665, Page(s) 797–809

Abstract: Multiple metabolic, immune and reproductive effects have been reported in fish residing in effluent-impacted sites. Natural stressors such as parasites also have been shown to impact the responses of organisms to chronic exposure to municipal effluent in ...

Abstract	Multiple metabolic, immune and reproductive effects have been reported in fish residing in effluent-impacted sites. Natural stressors such as parasites also have been shown to impact the responses of organisms to chronic exposure to municipal effluent in the St. Lawrence River (Quebec, Canada). In order to comprehensively evaluate the cumulative impacts of anthropogenic and natural stressors on the health of yellow perch, differential mRNA transcription profiles were examined in juvenile females collected from effluent-impacted and upstream sites with low or high infection levels of the larval trematode Apophallus brevis. Transcriptomics was used to identify biological pathways associated with environmental exposure. In total, 3463 isoforms were differentially transcribed between sites. Patterns reflecting the combined effects of stressors were numerically dominant, with a majority of downregulated transcripts (68%). The differentially expressed transcripts were associated with 27 molecular and cellular functions ranging from cellular development to xenobiotic metabolism and were involved in the development and function of 13 organ systems including hematological, hepatic, nervous, reproductive and endocrine systems. Based on RNA-seq results, sixteen genes were measured by qPCR. Significant differences were observed for six genes in fish exposed to both stressors combined, whereas parasites and effluent individually impacted the transcription of one gene. Lysozyme activity, lipid peroxidation, retinol-binding protein and glucose-6-phosphate dehydrogenase were selected as potential biomarkers of effects to study specific pathways of interest. Lipid peroxidation in perch liver was different between sites, parasite loads, and for combined stressors. Overall, results indicated that juvenile yellow perch responded strongly to combined parasite and effluent exposure, suggesting cumulative effects on immune responses, inflammation and lipid metabolism mediated by retinoid receptors. The present study highlight the importance of using a comprehensive approach combining transcriptomics and endpoints measured at higher levels of biological organization to better understand cumulative risks of contaminants and pathogens in aquatic ecosystems.
MeSH term(s)	Animals ; Female ; Fish Diseases/epidemiology ; Fish Diseases/parasitology ; Heterophyidae/physiology ; High-Throughput Nucleotide Sequencing ; Perches/metabolism ; Prevalence ; Quebec/epidemiology ; Trematode Infections/epidemiology ; Trematode Infections/parasitology ; Trematode Infections/veterinary ; Water Pollutants, Chemical/adverse effects
Chemical Substances	Water Pollutants, Chemical
Language	English
Publishing date	2019-02-13
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2019.02.155
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Zs.A 949: Show issues

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Article ; Online: The International Classification of Functioning, Disability and Health Core Set for deafblindness. Part I: a systematic review of outcome measures.

Paramasivam, Abinethaa / Jaiswal, Atul / Budhiraja, Shreya / Holzhey, Peter / Santhakumaran, Praveena / Ogedengbe, Tosin / Martin, Jana / DAS, Supriya / Côté, Samuel / Hassid, Romina / James, Tyler G / Kennedy, Beth / Tang, Diana / Tran, Yvvone / Colson-Osborne, Heather / Li Chen Che, Muriel / Minhas, Renu / Granberg, Sarah / Wittich, Walter

European journal of physical and rehabilitation medicine

2023 Volume 59, Issue 5, Page(s) 615–627

Abstract: Introduction: The International Classification of Functioning, Disability, and Health (ICF), developed by the World Health Organization, is a classification framework that focuses on the health and functioning of people with disabilities. As part of an ... ...

Abstract	Introduction: The International Classification of Functioning, Disability, and Health (ICF), developed by the World Health Organization, is a classification framework that focuses on the health and functioning of people with disabilities. As part of an ICF Core Set development, four studies need to be conducted, one of which is a systematic review. This study presents part 1 of the systematic review that aims to describe the outcome measures identified in the literature related to functioning in individuals with deafblindness. Evidence acquisition: The research team screened articles from eight scientific databases, three journals, and Google Scholar (March 2011 to September 2022). Articles were included if they studied individuals with deafblindness aged 18 and older. Studies that examined genetics or laboratory experiments involving animals were excluded. Data were extracted into a logbook with key descriptors such as study location and design, age of study population, and instruments/outcome measures used, which were further categorized into one of the following types: 1) standardized; 2) patient-reported measures, standardized (PT-S); 3) patient-reported measures, not standardized (PT-not S); 4) health professional, reported measures, standardized (HP-S); 5) Technical measures; 6) other measures (parent-reported standardized and laboratory measures). Evidence synthesis: The review included 147 studies, of which most were conducted in Europe (47.6%) and North America (27.9%). Of the 314 identified outcome measures, 57 were Standardized, 59 were Patient Reported-Standardized (PT-S), 178 were patient reported non-standardized (PT-Not S) variables, 11 were health professional reported, standardized, five were technical, and four were classified as other measures. Conclusions: Most instruments measured functioning in daily activities and the mental health of individuals with deafblindness. Three deafblind-specific instruments were identified in this study, highlighting the need for more deafblind-specific instruments to be developed and utilized in research.
MeSH term(s)	Humans ; International Classification of Functioning, Disability and Health ; Deaf-Blind Disorders ; Disabled Persons ; Outcome Assessment, Health Care ; World Health Organization ; Disability Evaluation ; Activities of Daily Living
Language	English
Publishing date	2023-07-17
Publishing country	Italy
Document type	Systematic Review ; Journal Article
ZDB-ID	2426908-6
ISSN	1973-9095 ; 1973-9087
ISSN (online)	1973-9095
ISSN	1973-9087
DOI	10.23736/S1973-9087.23.07890-5
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Article ; Online: The M/V X‑Press Pearl Nurdle Spill

Asha de Vos / Lihini Aluwihare / Sarah Youngs / Michelle H. DiBenedetto / Collin P. Ward / Anna P. M. Michel / Beckett C. Colson / Michael G. Mazzotta / Anna N. Walsh / Robert K. Nelson / Christopher M. Reddy / Bryan D. James

ACS Environmental Au, Vol 2, Iss 2, Pp 128-

Contamination of Burnt Plastic and Unburnt Nurdles along Sri Lanka’s Beaches

2021 Volume 135

Keywords	Environmental sciences ; GE1-350
Language	English
Publishing date	2021-11-01T00:00:00Z
Publisher	American Chemical Society
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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