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  1. Book ; Conference proceedings: Advances in endocrinology, metabolism and diabetes / 2

    Kochupillai, Narayana

    proceedings of the India-USA Symposium on Endocrinology, Metabolism and Diabetes - "EMD 1990" ; [New Delhi ... in December 1990]

    1994  

    Event/congress Indo-US Symposium on Endocrinology, Metabolism and Diabetes (EMD-90) (1990, Delhi)
    Author's details ed. N. Kochupillai
    Collection Advances in endocrinology, metabolism and diabetes
    Language English
    Size XIII, 291 S. : Ill., graph. Darst.
    Publisher Macmillan
    Publishing place New Delhi
    Publishing country India
    Document type Book ; Conference proceedings
    HBZ-ID HT007439923
    ISBN 0-333-92602-1 ; 978-0-333-92602-4
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 1561 -2- order for loan Magazin

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  2. Book ; Conference proceedings: Advances in endocrinology, metabolism and diabetes / 1

    Kochupillai, Narayana

    proceedings of the India-USA Symposium on Endocrinology, Metabolism and Diabetes - "EMD 1990" ; [New Delhi ... in December 1990]

    1992  

    Event/congress Indo-US Symposium on Endocrinology, Metabolism and Diabetes (EMD-90) (1990, Delhi)
    Author's details ed. N. Kochupillai
    Collection Advances in endocrinology, metabolism and diabetes
    Language English
    Size XIII, 338 S. : Ill., graph. Darst.
    Publisher Macmillan
    Publishing place New Delhi
    Publishing country India
    Document type Book ; Conference proceedings
    HBZ-ID HT007439930
    ISBN 0-333-92626-9 ; 978-0-333-92626-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1997 A 1561 -1- order for loan Magazin

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  3. Article: Long Sudarshan Kriya Yoga enhances cardiovascular and respiratory synchronization: An observational study.

    Chhabra, Deepika / Kharya, Chhaya / PremKrishanan, Archana / Singh, Priydarshan / Bhagat, Om Lata / Deepak, K K / Kochupillai, Vinod

    Journal of Ayurveda and integrative medicine

    2024  Volume 15, Issue 1, Page(s) 100867

    Abstract: ... than two years of experience participated in the study (n = 22; age 40.09 ± 12.68). The Electrocardiogram ...

    Abstract Background: Sudarshan Kriya Yoga (SKY - a rhythmic cyclic breathing) is known to produce several physiological changes in human body. Earlier it has been reported that SKY improves cardiovascular modulations, namely increase in heart rate variability.
    Objective: To observe the synchronization in oscillatory modulations in cardiac autonomic tone and ventilatory exchange during Long Sudarshan Kriya Yoga (LSKY). LSKY is a sequential combination of pranayama in ujjayi breath, bhastrika, and cyclic rhythmic breathing followed by yog-nidra.
    Methods: Regular LSKY practitioners from the Art of Living community with more than two years of experience participated in the study (n = 22; age 40.09 ± 12.68). The Electrocardiogram (ECG), respiration, oxygen saturation, and concentrations of oxygen and carbon-di-oxide from exhaled air were recorded before and during LSKY. The time domain parameters of heart rate variability (HRV) were calculated from ECG. All parameters were compared and correlated at each stage of LSKY.
    Results: Highly significant reciprocal correlation was found between HRV parameters and respiration rate during LSKY. Both O
    Conclusion: The autonomic parameters exhibited reciprocal response to respiratory rate and correlated well to the ventilatory parameters. Further during LSKY we observed enhanced synchronization. In conclusion the LSKY has a potential to influence cardiorespiratory parameters for improving the performance of both systems. LSKY - enhances oscillations in HRV that resets the autonomic system, indicative of better cardiac health and prepares body for better metabolic response. Such changes are capable of inducing resilience along with physiological, psychological relaxation and emotional well-being.
    Language English
    Publishing date 2024-01-21
    Publishing country United States
    Document type Journal Article
    ISSN 0975-9476
    ISSN 0975-9476
    DOI 10.1016/j.jaim.2023.100867
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Conference proceedings: Iodine nutrition thyroxine and brain development

    Kochupillai, Narayana

    proceedings of the International Symposium-cum-Workshop on Iodine Nutrition, Thyroxine and Brain Development ... New Delhi, from February 23 - 28, 1985

    1986  

    Event/congress International Symposium on Iodine Nutrition, Thyroxine and Brain Development (1985, Delhi)
    Author's details ed. N. Kochupillai
    Keywords Iodine / deficiency / congresses ; Hypothyroidism / congresses ; Brain / embryology / congresses ; Thyroid Hormones / congresses
    Size IX, 326 S. : Ill., graph. Darst.
    Publisher Tata McGraw-Hill Publ
    Publishing place New Delhi
    Publishing country India
    Document type Book ; Conference proceedings
    HBZ-ID HT003404614
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    1989 A 5088 order for loan Magazin

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  5. Article: The physiology of vitamin D : current concepts.

    Kochupillai, N

    The Indian journal of medical research

    2008  Volume 127, Issue 3, Page(s) 256–262

    Abstract: The vitamin D endocrine system, besides playing pivotal roles in calcium homeostasis & bone mineral metabolism, is now recognized to subserve a wide range of fundamental biological functions in cell differentiation, inhibition of cell growth as well as ... ...

    Abstract The vitamin D endocrine system, besides playing pivotal roles in calcium homeostasis & bone mineral metabolism, is now recognized to subserve a wide range of fundamental biological functions in cell differentiation, inhibition of cell growth as well as immuno modulation. Vitamin D is a prohormone which is converted into its active hormonal form 1, 25 (OH)D2 D, 1, 25 (OH)D2 D activates its cellular receptor (VDR) which activate target genes to engender its biological actions. This review provides a summary of recent understanding of the complex actions of the vitamin D hormone 1, 25 (OH)2 D which is a final product of 1alpha hydroxylation in the proximal tubular cells of kidneys. Emerging evidence also indicates both 1, 25 (OH)2 D3 independent as well as depended action of vitamin D receptor (VDR). Thus, the vitamin D system action may involve more than one single receptor and legand. The presence of 1alpha hydroxylase in many target cells other than proximal renal tubular cells indicates autocrine and paracrine functions for 1, 25 (OH)2 D3 in the control of cell proliferation and differentiation. Vitamin D and related molecules belong to a elaborate endocrine system that acts on target genomic receptors in several organ systems to control cell proliferation and differentiation.
    MeSH term(s) Bone Density/physiology ; Bone and Bones/physiology ; Calcium/physiology ; Endocrine System/physiology ; Humans ; Receptors, Calcitriol/physiology ; Vitamin D/physiology
    Chemical Substances Receptors, Calcitriol ; Vitamin D (1406-16-2) ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2008-03
    Publishing country India
    Document type Journal Article ; Review
    ZDB-ID 390883-5
    ISSN 0971-5916 ; 0019-5340
    ISSN 0971-5916 ; 0019-5340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.143: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Effect of fetal liver condition media derived cytokines(IL-6 and Flt-3) on human bone marrow stem cells colony formation.

    Bhardwaj, Rashmi / Kumar, Lalit / Chhabra, Deepika / Mohanty, Sujata / Sharma, Atul / Mehra, N K / Kochupillai, Vinod

    Cytokine

    2022  Volume 153, Page(s) 155863

    Abstract: Earlier research from our laboratory demonstrated the presence of stimulatory activity of different growth factors in the fetal liver (FL) extracts when collected in a medium known as fetal liver conditioned medium (FLCM) using Enzyme-linked ... ...

    Abstract Earlier research from our laboratory demonstrated the presence of stimulatory activity of different growth factors in the fetal liver (FL) extracts when collected in a medium known as fetal liver conditioned medium (FLCM) using Enzyme-linked Immunosorbent Assay (ELISA). In the present study, we have assessed two other cytokines viz. IL-6 and FMS like tyrosine kinase-3 (Flt-3) with the help of bioneutralization assay. FLCM was prepared by incubating fetal liver cells with Iscove's Modified Dulbecco's Medium (IMDM) containing 10% fetal bovine serum (FBS) and 10% Phytohemagglutinin and collected after 24hrs, 48hrs, 72 hrs. and on the 7th day of incubation. Clonal cultures were established for 1 X 10
    MeSH term(s) Bone Marrow Cells ; Cells, Cultured ; Colony-Forming Units Assay ; Culture Media, Conditioned/pharmacology ; Cytokines/pharmacology ; Erythropoietin ; Humans ; Interleukin-3/pharmacology ; Interleukin-6/pharmacology ; Liver ; Megakaryocytes ; Plant Extracts/pharmacology ; fms-Like Tyrosine Kinase 3
    Chemical Substances Culture Media, Conditioned ; Cytokines ; Interleukin-3 ; Interleukin-6 ; Plant Extracts ; Erythropoietin (11096-26-7) ; fms-Like Tyrosine Kinase 3 (EC 2.7.10.1)
    Language English
    Publishing date 2022-03-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1018055-2
    ISSN 1096-0023 ; 1043-4666
    ISSN (online) 1096-0023
    ISSN 1043-4666
    DOI 10.1016/j.cyto.2022.155863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2840: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: In vitro expansion of fetal liver hematopoietic stem cells.

    Bhardwaj, Rashmi / Kumar, Lalit / Chhabra, Deepika / Mehra, N K / Sharma, Atul / Mohanty, Sujata / Kochupillai, Vinod

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 11879

    Abstract: Fetal liver hematopoietic stem and progenitor cells (HSPCs) have been considered appropriate for the management of aplastic anemia owing to their proliferative potential. Bone marrow recovery was possible in some cases; the engraftment potential of these ...

    Abstract Fetal liver hematopoietic stem and progenitor cells (HSPCs) have been considered appropriate for the management of aplastic anemia owing to their proliferative potential. Bone marrow recovery was possible in some cases; the engraftment potential of these cells, however was unsatisfactory, possibly due to the availability of a smaller number of these cells from a single fetus. The present study explores how we can expand fetal liver hematopoietic stem cells under in vitro conditions. We isolated mononuclear cells from fetal liver and hematopoietic stem cells were identified and analyzed by cell surface marker CD34. CD34
    MeSH term(s) Animals ; Antigens, CD34/biosynthesis ; Cell Culture Techniques ; Cell Separation ; Cell Survival ; Cytokines/metabolism ; Female ; Hematopoietic Stem Cells/cytology ; In Vitro Techniques ; Kinetics ; Leukocytes, Mononuclear/cytology ; Liver/embryology ; Magnetics ; Male ; Mice ; Stem Cells/cytology
    Chemical Substances Antigens, CD34 ; Cytokines
    Language English
    Publishing date 2021-06-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-91272-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Effects of Sudarshan KriyaYoga and Advanced Meditation Program on Genetic Expression of Pro-inflammatory and Antioxidants Genes.

    Bhaskar, Lakshmi / Kharya, Chhaya / Debnath, Monojith / Mullapudi, Thrinath / Subbanna, Manjula / Chhabra, Deepika / Kumar, Neeta / Sharma, Prem Prakash / Bhagat, Om Lata / Kochupillai, Vinod

    Cureus

    2023  Volume 15, Issue 7, Page(s) e41377

    Abstract: Background Stress leads to immune system dysregulation and dyshomeostasis at the gene level. Mind-body practices are known to influence genomic expression, leading to better health and quality of life. Objective To assess the effect of Advanced ... ...

    Abstract Background Stress leads to immune system dysregulation and dyshomeostasis at the gene level. Mind-body practices are known to influence genomic expression, leading to better health and quality of life. Objective To assess the effect of Advanced Meditation Program (AMP) on the mRNA expression of pro-inflammatory and antioxidative genes among those already practicing Sudarshan Kriya Yoga (SKY). Methods A total of 97 healthy volunteers participated in the study, distributed into two groups. The Group I SKY practitioners attended a four-day AMP (50 participants with an average age of 38.8 ± 11.9 consisting of 37 females and 13 males); they are first-time participants of the AMP. Group II SKY practitioners, on the other hand, consisted of 47 participants with an average age of 36.4 ± 9.3 with 43 females and four males. At day 0, day 5, and day 90, the mRNA expression of pro-inflammatory genes, namely interleukin (IL) 1β, IL6, and the tumor necrosis factor (TNF), and the expression of antioxidative genes, namely superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) was observed. The data were analysed in two phases due to the emergence of coronavirus disease 2019 (COVID-19): (i) pre-COVID-19 and (ii) during COVID-19. Results In the pre-COVID-19 data set, IL1β, IL6, and TNF were found to have decreased in both groups. There is a significant increase in the expression of SOD and catalase in Group I and a decrease in Group II by day 90. During COVID-19, pro-inflammatory genes increased in Group I and had no significant change in Group II. All three antioxidant genes had decreased expression by day 90 in Group I; SOD decreased in Group II. Interpretation and conclusions Reduced expression of pro-inflammatory genes and increase in the expression of antioxidative genes during the pre-COVID-19 time suggest that the practice of SKY and added AMP may enhance antioxidative defense and may reduce the chance of getting diseases related to inflammation in the body.
    Language English
    Publishing date 2023-07-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.41377
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effect of Sudarshan Kriya Yoga (SKY) on daytime and situational sleep propensity in novice practitioners: a prospective cohort study.

    Chaudhari, Kaustubh S / Chaudhari, Saurabh S / Rankhambe, Harshali B / Kochupillai, Vinod / Tiwari, Rakesh R

    Journal of complementary & integrative medicine

    2020  Volume 18, Issue 3, Page(s) 585–592

    Abstract: ... experience in SKY. Subjects (n=52) performed 30 min of SKY for 6 days/week for 8 weeks, while controls (n=53 ...

    Abstract Objectives: Hectic, late-night lifestyle has reduced 90 min sleep in 20% adults resulting in insomnia and excessive daytime sleepiness (EDS). We assess the scope of Sudarshan Kriya Yoga (SKY), a 4-component, breathing process in reducing EDS, generally and situationally.
    Methods: This is a prospective, controlled study involving randomized subjects without any sleep-wake cycle anomalies and prior experience in SKY. Subjects (n=52) performed 30 min of SKY for 6 days/week for 8 weeks, while controls (n=53) performed sitting activity and Suryanamaskar for 4-weeks each. Epworth Sleepiness Scale (ESS) was used to measure EDS at 0, 4, and 8 weeks.
    Results: SKY group showed significant ESS score improvements between 0-4 weeks and 4-8 weeks of 1.22 (p=0.0001) and 1.66 (p=0.001) respectively. Controls however failed to improve with score differences of 0.02 (p=0.892) and 0.02 (p=0.8212) respectively. SKY group showed significant ESS score improvement over controls at 4-weeks (difference=1.74; p=0.013) and 8-weeks (difference eight; p=0.0001). Improvement was most for obese people and those sitting in a halted car.
    Conclusions: Improvement in subjects' nighttime sleep and daytime wakefulness in SKY practitioners can be attributed to polyvagal theory. Increased heart rate variability (HRV) alterations and sympathetic hyperarousal in chronic insomnia; and cholinergic and GABAergic dysregulation in anxiety disorders are countered by regulated vagal nerve stimulation post SKY. Our study establishes effectivity of SKY in reducing EDS (total and situational), provides a clinical correlation for prior polysomnographic evidence and paves way for larger trials directed towards SKY prescriptions for insomnia.
    MeSH term(s) Adult ; Anxiety Disorders ; Humans ; Prospective Studies ; Respiration ; Sleep ; Yoga
    Language English
    Publishing date 2020-09-03
    Publishing country Germany
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2197618-1
    ISSN 1553-3840 ; 2194-6329
    ISSN (online) 1553-3840
    ISSN 2194-6329
    DOI 10.1515/jcim-2020-0172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Iodine deficiency and neonatal hypothyroidism / N. Kochupillai . [et al.]

    Kochupillai, N / Pandav, C. S / Godbole, M. M / Mehta, M / Ahuja, M. M. S

    1986  

    Keywords Hypothyroidism ; Iodine ; India ; Organization of Health Care and Social Development ; epidemiology in infancy and childhood ; deficiency
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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