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  1. Book ; Thesis: Vergleichende Evaluation des HemochronR Signature Elite und des Abbott i-STATR zur Messung der Activated Clotting Time (ACT) bei Herzoperationen

    Nagy, Elisabeth

    2017  

    Institution Universität Duisburg-Essen
    Author's details vorgelegt von dr. med. univ. Elisabeth Nagy
    Language German
    Size 70 Blätter, Illustrationen
    Publishing place Duisburg ; Essen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Duisburg-Essen, 2017
    HBZ-ID HT019539983
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: The presence and future of the journal Anaerobe.

    Nagy, Elisabeth

    Anaerobe

    2021  Volume 69, Page(s) 102391

    MeSH term(s) Bacteria, Anaerobic/genetics ; Bacteria, Anaerobic/physiology ; Editorial Policies ; Humans ; Journal Impact Factor ; Periodicals as Topic/standards ; Periodicals as Topic/trends
    Language English
    Publishing date 2021-06-08
    Publishing country England
    Document type Editorial
    ZDB-ID 1237621-8
    ISSN 1095-8274 ; 1075-9964
    ISSN (online) 1095-8274
    ISSN 1075-9964
    DOI 10.1016/j.anaerobe.2021.102391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Proteomics-Based RT-qPCR and Functional Analysis of 18 Genes in Metronidazole Resistance of

    Mahmood, Bakhtiyar / Paunkov, Ana / Kupc, Malgorzata / Burián, Katalin / Nagy, Elisabeth / Leitsch, David / Sóki, József

    Antibiotics (Basel, Switzerland)

    2024  Volume 13, Issue 3

    Abstract: Previously, we reported that metronidazole MICs are not dependent on the expression levels ... ...

    Abstract Previously, we reported that metronidazole MICs are not dependent on the expression levels of
    Language English
    Publishing date 2024-02-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics13030207
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: What do we know about the diagnostics, treatment and epidemiology of Clostridioides (Clostridium) difficile infection in Europe?

    Nagy, Elisabeth

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

    2017  Volume 24, Issue 3, Page(s) 164–170

    Abstract: Clostridium difficile, recently reclassified as Clostridioides difficile is responsible for a significant part of diarrheal diseases in the hospitals and in the community. Besides the main pathogenic factors, toxin A, toxin B and the binary toxin, ... ...

    Abstract Clostridium difficile, recently reclassified as Clostridioides difficile is responsible for a significant part of diarrheal diseases in the hospitals and in the community. Besides the main pathogenic factors, toxin A, toxin B and the binary toxin, several other putative virulence factors have been investigated. This manuscript summarize recent findings in Europe concerning source of infection, epidemiology of CDI, the changing pattern of PCR ribotypes of C. difficile strains in different European countries, recommendations for diagnosis and treatment of CDI.
    MeSH term(s) Clostridium Infections/diagnosis ; Clostridium Infections/epidemiology ; Clostridium Infections/therapy ; Clostridium difficile/classification ; Clostridium difficile/isolation & purification ; Europe/epidemiology ; Hospitals/statistics & numerical data ; Humans ; Polymerase Chain Reaction/methods ; Ribotyping ; Risk Factors
    Language English
    Publishing date 2017-12-27
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1355399-9
    ISSN 1437-7780 ; 1341-321X
    ISSN (online) 1437-7780
    ISSN 1341-321X
    DOI 10.1016/j.jiac.2017.12.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Novel and rare β-lactamase genes of Bacteroides fragilis group species: Detection of the genes and characterization of their genetic backgrounds.

    Mahmood, Bakhtiyar / Sárvári, Károly Péter / Orosz, Laszló / Nagy, Elisabeth / Sóki, József

    Anaerobe

    2024  Volume 86, Page(s) 102832

    Abstract: Objectives: This study screened the prevalence of rare β-lactamase genes in Bacteroides fragilis group strains from clinical specimens and normal microbiota and examined the genetic properties of the strains carrying these genes.: Methods: blaHGD1, ... ...

    Abstract Objectives: This study screened the prevalence of rare β-lactamase genes in Bacteroides fragilis group strains from clinical specimens and normal microbiota and examined the genetic properties of the strains carrying these genes.
    Methods: blaHGD1, blaOXA347, cblA, crxA, and pbbA were detected by real-time polymerase chain reaction in collections of Bacteroides strains from clinical (n = 406) and fecal (n = 184) samples. To examine the genetic backgrounds of the samples, end-point PCR, FT-IR, and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry were used.
    Results: All B. uniformis isolates were positive for cblA in both collections. Although crxA was B. xylanisolvens-specific and associated with carbapenem resistance, it was only found in six fecal and three clinical B. xylanisolvens strains. Moreover, the crxA-positive strains were not clonal among B. xylanisolvens (contrary to cfiA in B. fragilis), implicating a rate of mobility or emergence by independent evolutionary events. The Phocaeicola (B.) vulgatus/P. dorei-specific gene blaHGD1 was detected among all P. vulgatus/P. dorei isolates from fecal (n = 36) and clinical (n = 26) samples. No blaOXA347-carrying isolate was found from European collections, but all US samples (n = 6) were positive. For three clinical isolates belonging to B. thetaiotaomicron (n = 2) and B. ovatus (n = 1), pbbA was detected on mobile genetic elements, and pbbA-positive strains displayed non-susceptibility to piperacillin or piperacillin/tazobactam phenotypically.
    Conclusions: Based on these observations, β-lactamases produced by rare β-lactamase genes in B. fragilis group strains should not be overlooked because they could encode important resistance phenotypes.
    MeSH term(s) beta-Lactamases/genetics ; beta-Lactamases/metabolism ; Humans ; Bacteroides Infections/microbiology ; Bacteroides fragilis/genetics ; Bacteroides fragilis/enzymology ; Bacteroides fragilis/isolation & purification ; Bacteroides fragilis/drug effects ; Feces/microbiology ; Anti-Bacterial Agents/pharmacology ; Microbial Sensitivity Tests ; Bacterial Proteins/genetics
    Chemical Substances beta-Lactamases (EC 3.5.2.6) ; Anti-Bacterial Agents ; Bacterial Proteins
    Language English
    Publishing date 2024-02-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 1237621-8
    ISSN 1095-8274 ; 1075-9964
    ISSN (online) 1095-8274
    ISSN 1075-9964
    DOI 10.1016/j.anaerobe.2024.102832
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Message from the Editor-in-Chief.

    Nagy, Elisabeth

    Anaerobe

    2015  Volume 31, Page(s) 1

    MeSH term(s) Anaerobiosis ; Animals ; Bacteria, Anaerobic/drug effects ; Bacteria, Anaerobic/isolation & purification ; Bacterial Infections/diagnosis ; Bacterial Infections/drug therapy ; Bacterial Infections/microbiology ; Editorial Policies ; Fungi/drug effects ; Fungi/isolation & purification ; Mycoses/diagnosis ; Mycoses/drug therapy ; Mycoses/microbiology ; Parasites/drug effects ; Parasites/isolation & purification ; Parasitic Diseases/diagnosis ; Parasitic Diseases/drug therapy ; Parasitic Diseases/parasitology ; Periodicals as Topic
    Language English
    Publishing date 2015-02
    Publishing country England
    Document type Editorial
    ZDB-ID 1237621-8
    ISSN 1095-8274 ; 1075-9964
    ISSN (online) 1095-8274
    ISSN 1075-9964
    DOI 10.1016/j.anaerobe.2014.11.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: An update on ampicillin resistance and β-lactamase genes of

    Sóki, József / Keszőcze, Anikó / Nagy, István / Burián, Katalin / Nagy, Elisabeth

    Journal of medical microbiology

    2021  Volume 70, Issue 8

    Abstract: Introduction. ...

    Abstract Introduction.
    MeSH term(s) Ampicillin Resistance/genetics ; Bacterial Proteins/genetics ; Bacteroides Infections/microbiology ; Bacteroides fragilis/genetics ; Genes, Bacterial ; beta-Lactamases/genetics
    Chemical Substances Bacterial Proteins ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2021-08-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 218356-0
    ISSN 1473-5644 ; 0022-2615
    ISSN (online) 1473-5644
    ISSN 0022-2615
    DOI 10.1099/jmm.0.001393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: First Report of Fusarium oxysporum f. sp. lactucae Race 1 Causing Fusarium Wilt of Lettuce in Norway.

    Herrero, Maria Luz / Nagy, Nina Elisabeth / Solheim, Halvor

    Plant disease

    2021  

    Abstract: Lettuce (Lactuca sativa L.) is produced in Norway both in field and greenhouses. In Norway, greenhouse lettuce is one of the most important vegetables grown year-round. In winter 2018, wilting symptoms were observed on soil-grown lettuce of the cultivar ... ...

    Abstract Lettuce (Lactuca sativa L.) is produced in Norway both in field and greenhouses. In Norway, greenhouse lettuce is one of the most important vegetables grown year-round. In winter 2018, wilting symptoms were observed on soil-grown lettuce of the cultivar Frillice in a greenhouse in south east Norway (Buskerud county). Affected plants showed stunted growth, wilting of outer leaves, and brownish discoloration of vascular tissues of taproots and crowns. According to the producer, the disease led to an estimated 10% of yield losses. Fungal isolates were obtained from crowns and roots of diseased plants collected from the greenhouse in 2018 and 2019. Two single spore isolates, 231274 from 2018 and 231725 from 2019, were used in further studies. The isolates were incubated on synthetic nutrient-poor agar (SNA) at 18-20 ⁰C, and a 12 hours dark, 12 hours UV light cycle. Isolate 231274 produced abundant macro- and microconidia characteristics of Fusarium oxysporum while macroconidia were never observed in isolate 231725. On potato dextrose agar (PDA), colonies of isolate 231274 were purple in color and colonies of isolate 231725 were pinkish with abundant aerial mycelium. For PCR-assay, DNA from mycelia was extracted using Easy-DNA kit (Invitrogen). A portion of the translation elongation factor 1-α (EF1-α) gene was amplified using primers F-728F (Carbone and Kohn. 1999) and EF2 (O'Donnell et al. 1998) as described by Aas et al. 2018. Blast analysis of both sequences (accession no. MW316853 for 231274 and MW316854 for 231275) obtained a 99% homology with the sequence of Fusarium oxysporum f.sp. lactucae (FOL) race 1 strain S1 (accession no. DQ837657)(Mbofung et al. 2007). Both isolates were identified as race 1 by using specific primers Hani3' and Hanilatt3rev (Pasquali et al. 2007) as described by Cabral et al. 2014. To complete Koch's postulate, lettuce plants of the cultivar Frillice were used. Race identity was confirmed using the differential lettuce cultivars Costa Rica No.4 (resistant to FOL race 1), Banchu Red Fire (resistant to FOL races 2 and 4) and Romana Romabella (resistant to FOL races 1 and 2) (Gilardi et al. 2017) provided by the breeding company Rijk Zwaan (De Lier, The Netherlands). For inoculation, roots of six 2-weeks old seedlings per cultivar were dipped in a spore suspension (1 x 106 CFU/ml) for 1 min, while controls were dipped in distilled water. Seedlings were planted in 250 ml pots containing fertilized potting substrate, and were placed in a greenhouse with temperature ranging from 15 to 35 ⁰C and an average of 23 ⁰C. After 10 days reduced growth was observed in cultivars Frillice and Banchu Red Fire for both fungal isolates. After 25 days wilting was observed in both cultivars. Affected plants presented discoloration of vascular tissue. No difference in growth was observed between cultivars Romana Romabella and Costa Rica No. 4 and their respective controls. FOL was re-isolated from all inoculated cultivars but not from controls. The colony patterns of the recovered isolates were the same than those of the isolates used for inoculation. These results confirm that the isolate belongs to race 1. Greenhouse lettuce in Norway is mainly produced in hydroponics. FOL is here reported to cause damages in soil- grown lettuce. Nevertheless FOL in hydroponic systems has been reported in Japan (Fujinaga et al. 2003) and Thailand (Thongkamngam and Jaenaksorn 2017). Thus, the possibility of infections in hydroponics remain a big concern for lettuce production in Norway.
    Language English
    Publishing date 2021-04-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 754182-x
    ISSN 0191-2917
    ISSN 0191-2917
    DOI 10.1094/PDIS-01-21-0134-PDN
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Advancing MALDI-TOF MS applications in anaerobic bacteriology.

    Nagy, Elisabeth / Schuetz, Audrey

    Anaerobe

    2018  Volume 54, Page(s) 189–190

    MeSH term(s) Bacteria, Anaerobic/chemistry ; Bacteria, Anaerobic/classification ; Bacteria, Anaerobic/genetics ; Bacteria, Anaerobic/isolation & purification ; Bacterial Infections/microbiology ; Bacterial Typing Techniques/methods ; Bacterial Typing Techniques/trends ; Bacteriological Techniques/methods ; Bacteriological Techniques/trends ; Humans ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/methods ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization/trends
    Language English
    Publishing date 2018-10-25
    Publishing country England
    Document type Editorial
    ZDB-ID 1237621-8
    ISSN 1095-8274 ; 1075-9964
    ISSN (online) 1095-8274
    ISSN 1075-9964
    DOI 10.1016/j.anaerobe.2018.10.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Phenotypic and Molecular Characterization of Carbapenem-Heteroresistant

    Baaity, Zain / von Loewenich, Friederike D / Nagy, Elisabeth / Orosz, László / Burián, Katalin / Somogyvári, Ferenc / Sóki, József

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 5

    Abstract: Carbapenem- ... ...

    Abstract Carbapenem-resistant
    Language English
    Publishing date 2022-04-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11050590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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