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Article ; Online: Total parenteral nutrition for patients with gastrointestinal cancers: a clinical practice review.

Zametkin, Emily / Guyer, Dana / Tarshish, Yael / Bash, Kinan / Almhanna, Khaldoun

2023 Volume 12, Issue 5, Page(s) 1072–1080

Abstract: The use of total parenteral nutrition (TPN) in patients with gastrointestinal cancers is a well-established practice, yet there is substantial variability in its use across institutions. Decision-making around the initiation of TPN is complex. An ... ...

Abstract	The use of total parenteral nutrition (TPN) in patients with gastrointestinal cancers is a well-established practice, yet there is substantial variability in its use across institutions. Decision-making around the initiation of TPN is complex. An interdisciplinary team can help identify patient factors and clinical situations that influence whether a patient is likely to benefit from parenteral nutrition. We present the case of a woman with a gastrointestinal cancer who benefited from the initiation of TPN as a bridge therapy to further cancer treatment. This case highlights the importance of establishing a plan for nutrition with specific goals in mind, such as optimizing patients for more cancer-directed therapy. Although patients with gastrointestinal cancers may be candidates for TPN, many patient-specific factors, such as functional status and opportunities for future treatments, must be considered prior to the initiation of parenteral nutrition. An interdisciplinary approach should be used to make recommendations based on patient goals, with a focus on patient and cancer characteristics that are associated with positive outcomes after initiation of TPN. These characteristics include functional status, nutritional status, degree of symptom control, and ability to safely administer nutrition. It is important to continually assess whether parenteral nutrition is beneficial in respect to a patient's preferences and prognosis.
MeSH term(s)	Female ; Humans ; Gastrointestinal Neoplasms/therapy ; Nutritional Status ; Parenteral Nutrition, Total/methods
Language	English
Publishing date	2023-08-21
Publishing country	China
Document type	Case Reports ; Review ; Journal Article
ZDB-ID	2828544-X
ISSN	2224-5839 ; 2224-5839
ISSN (online)	2224-5839
ISSN	2224-5839
DOI	10.21037/apm-22-1380
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Aging Equines: Understanding the Experience of Caring for a Geriatric Horse with a Chronic Condition.

Ballou, Megan E / Mueller, Megan K / Dowling-Guyer, Seana

Journal of equine veterinary science

2020 Volume 90, Page(s) 102993

Abstract: This study evaluated the experience of 1,448 people in the United States who currently care for or had previously cared for a geriatric horse and how that experience was qualified by the presence or absence of a chronic condition in the horse. An ... ...

Abstract	This study evaluated the experience of 1,448 people in the United States who currently care for or had previously cared for a geriatric horse and how that experience was qualified by the presence or absence of a chronic condition in the horse. An anonymous, online questionnaire was distributed to a cross-country sample to investigate the burden of caregivers from the perspective of owners of geriatric horses. Traumatic events and veterinary care decisions were also explored. Findings from the study supported the hypothesis that owners of geriatric horses with a chronic condition experienced higher levels of physical and emotional care burden, regardless of the age of the geriatric horse. Attachment levels reported by participants were high, regardless of the health status of the horse. This exploratory study provides the equine practitioner a greater understanding of the care burden experienced by owners of geriatric horses, particularly of owners of geriatric horses with a chronic condition, who rely on their veterinarian to guide their management and health care decisions. Veterinarians can help prepare and support clients as they navigate the complexities of caring for an older horse with a chronic condition.
MeSH term(s)	Aged ; Aging ; Animals ; Chronic Disease ; Horse Diseases ; Horses ; Humans ; Surveys and Questionnaires ; United States ; Veterinarians
Language	English
Publishing date	2020-03-25
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2102631-2
ISSN	1542-7412 ; 0737-0806
ISSN (online)	1542-7412
ISSN	0737-0806
DOI	10.1016/j.jevs.2020.102993
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Article ; Online: What matters: Factors impacting the recovery process among outpatient mental health service users.

Garverich, Suzanne / Prener, Christopher G / Guyer, Margaret E / Lincoln, Alisa K

Psychiatric rehabilitation journal

2020 Volume 44, Issue 1, Page(s) 77–86

Abstract: Objective: Understanding factors that promote and hinder the recovery process for people living with serious mental illness remains of critical importance. We examine factors, including limited literacy, associated with mental health recovery among ... ...

Abstract	Objective: Understanding factors that promote and hinder the recovery process for people living with serious mental illness remains of critical importance. We examine factors, including limited literacy, associated with mental health recovery among public mental health service users. Method: This study uses data from a mixed-methods, service-user informed project focused on the impact of limited literacy in the lives of people with serious mental illness. Data from structured interviews evaluate perceptions of recovery as assessed with the Recovery Assessment Scale (RAS). Regression models examine factors related to recovery controlling for sociodemographic factors, literacy, neurocognition, mental health status, perceived social support, and stigma. Results: Despite bivariate relationships between RAS and limited literacy, the full models suggest that other factors account for this relationship. These include mental health status, higher social support, higher self-reported community status, and higher stigma consciousness, as well as race for some models. Conclusions and implications for practice: Our findings that social support and perceptions of community status are associated with higher scores on the RAS echo prior work demonstrating the importance of social connection and context in mental health recovery. Though literacy was not a predictor of recovery, further research should examine the relationship between literacy and recovery given the deep literature on literacy on health outcomes. In order to better support people in the recovery process it is important that more research is done to examine the complex relationship between stigma consciousness and recovery as well as understand the racial disparities that exist within the recovery subscales. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
MeSH term(s)	Humans ; Mental Disorders ; Mental Health Services ; Outpatients ; Social Stigma ; Social Support
Language	English
Publishing date	2020-04-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	2070454-9
ISSN	1559-3126 ; 1095-158X
ISSN (online)	1559-3126
ISSN	1095-158X
DOI	10.1037/prj0000407
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Article ; Online: Maternal socialization of emotion and the development of emotion regulation in early adolescent girls.

Berona, Johnny / Sroka, Anna W / Gelardi, Kristina L / Guyer, Amanda E / Hipwell, Alison E / Keenan, Kate

Emotion (Washington, D.C.)

2022 Volume 23, Issue 3, Page(s) 872–878

Abstract: Regulation of negative emotions is a core competency of child development. Parental emotion socialization profoundly influences later capacity to regulate negative affect in childhood and adolescence. The present study examined the effects of maternal ... ...

Abstract	Regulation of negative emotions is a core competency of child development. Parental emotion socialization profoundly influences later capacity to regulate negative affect in childhood and adolescence. The present study examined the effects of maternal emotion socialization on the development of emotion regulation in the context of a longitudinal study of 210 mother-daughter dyads. Dyads completed a conflict resolution task when the child was age 11 years during which maternal warmth and hostility were coded. At ages 11 to 13 years, mothers completed self-report measures of supportive and nonsupportive responses to child negative emotion, and children completed self-reports of inhibition and adaptive regulation of sadness and anger. We used latent growth curve modeling to estimate changes in inhibition and adaptive regulation of sadness and anger over time; observed maternal warmth and hostility were included as time-invariant covariates and maternal self-report of supportive and nonsupportive responses were included as time-varying covariates. Observed maternal warmth was positively associated with girls' adaptive regulation of anger and sadness at age 11 years. Maternal self-reported supportive responses to girls' negative affect were positively associated with girls' adaptive regulation of anger, and nonsupportive responses were negatively associated with adaptive regulation of anger and sadness. These findings support the role of maternal emotion socialization and indicate specific effects of maternal warmth and supportive responses in the development of girls' capacity to modulate negative emotions during early adolescence. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
MeSH term(s)	Child ; Female ; Humans ; Adolescent ; Emotional Regulation ; Socialization ; Mother-Child Relations/psychology ; Longitudinal Studies ; Emotions/physiology ; Mothers/psychology
Language	English
Publishing date	2022-08-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2102391-8
ISSN	1931-1516 ; 1528-3542
ISSN (online)	1931-1516
ISSN	1528-3542
DOI	10.1037/emo0001110
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Article ; Online: Financial fragility and demographic factors predict pet owners' perceptions of access to veterinary care in the United States.

King, Erin / Mueller, Megan K / Dowling-Guyer, Seana / McCobb, Emily

Journal of the American Veterinary Medical Association

2022 Volume 260, Issue 14, Page(s) 1–8

Abstract: Objective: Access to veterinary care is critical for pet, human, and community health. However, inequities in how easily pet owners can access veterinary care may exacerbate health disparities in vulnerable populations. This research analyzed pet owners' ...

Abstract	Objective: Access to veterinary care is critical for pet, human, and community health. However, inequities in how easily pet owners can access veterinary care may exacerbate health disparities in vulnerable populations. This research analyzed pet owners' perceptions of access to veterinary care in order to understand how demographic characteristics and financial fragility predict perceived access to veterinary services. Sample: This study utilized survey data (n = 750) from a larger cross-sectional survey of adults in the US conducted by the Tufts University Equity Research Group. Procedures: Survey data were collected in May and June of 2020 from a nationally representative group of pet owners via an online panel. Descriptive statistics, ANOVAs, and a sequential linear regression model were conducted in order to predict perceived access to veterinary care. Results: Results of a sequential linear regression model indicated that race or ethnicity, education, and financial fragility significantly predicted perceived ease of access to veterinary care (F[7,617] = 19.80; P < .001). Additionally, financial fragility was prevalent among most pet owners of almost all income brackets, highlighting the need for more research into the cost burden of veterinary care. Clinical relevance: Future studies should focus on diverse sampling strategies that capture the experiences of minority pet owners in order to further understand issues of access in veterinary medicine.
MeSH term(s)	Humans ; United States ; Animals ; Ownership ; Cross-Sectional Studies ; Surveys and Questionnaires ; Demography
Language	English
Publishing date	2022-04-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	390811-2
ISSN	1943-569X ; 0003-1488
ISSN (online)	1943-569X
ISSN	0003-1488
DOI	10.2460/javma.21.11.0486
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Article ; Online: Performing an Organizational Health Literacy Assessment in a Shelter Serving People with Mental Illness.

Rosenfeld, Lindsay / Miller, Anna / Garverich, Suzanne / Guyer, Margaret / Steiner, Rachel / Lincoln, Alisa K

Health literacy research and practice

2022 Volume 6, Issue 3, Page(s) e167–e174

Abstract: ... e.g., welcoming atmosphere) and barriers (e.g., unclear signage). Document assessment also revealed ... contain both facilitating factors (e.g., chunked sections) and barriers (e.g., jargon, mismatched graphics ...

Abstract	Background: Health literacy research and practice are constantly evolving. Recent inquiry has highlighted the burdensome literacy demands faced by people with serious mental illness (SMI). Systems, organizational operations, and structures can play a role in decreasing literacy demand, thereby reducing unnecessary challenges for people with SMI. Brief Description of Activity: An organizational health literacy assessment was conducted to explore literacy demands in one mental health shelter and revealed best practice action steps for improving the literacy environment. Implementation: The assessment included an exploration of the shelter environment using The Health Literacy Environment Activity Packet, First Impressions & Walking Interview, and a commonly used shelter document using the Simple Measure of Gobbledygook (SMOG), Suitability Assessment of Materials (SAM), and Centers for Disease Control and Prevention (CDC) Index. Results: The literacy demands of the shelter environment and a frequently used document exceeded the literacy skills of people with SMI. Environment assessment revealed environmental facilitators (e.g., welcoming atmosphere) and barriers (e.g., unclear signage). Document assessment also revealed facilitating factors and barriers. SMOG scores ranged from 11.25 to 11.80 (median: 11.38), meaning 11th to 12th grade-level reading skills are required to understand, use, and take action on the document's content. A SAM score of 50% (adequate) and a CDC Index score of 42.1 (revise and improve) reveal materials contain both facilitating factors (e.g., chunked sections) and barriers (e.g., jargon, mismatched graphics) to use. Lessons learned: The mismatch between system demands and the literacy skills of people with SMI is more profound than that of the general United States population. Organizational health literacy assessments are achievable and useful for both immediate and long-term action aimed at understanding and improving the organizational health literacy of mental health spaces. Further work is needed to explore the role of behavioral health services in addressing the institutional and programmatic literacy demands that inhibit treatment and recovery. [
MeSH term(s)	Adult ; Educational Status ; Health Literacy ; Humans ; Mental Disorders/therapy ; Organizations ; Smog ; United States
Chemical Substances	Smog
Language	English
Publishing date	2022-07-08
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ISSN	2474-8307
ISSN (online)	2474-8307
DOI	10.3928/24748307-20220615-01
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Article: The present state of aspirin and clopidogrel resistance.

Guyer, K E

Hamostaseologie

2009 Volume 29, Issue 3, Page(s) 285–290

Abstract: Antiplatelet therapy has demonstrated significant clinical benefit in the treatment of acute coronary syndrome. However, as with any treatment strategy it has been unable to prevent all cardiovascular events. This is far from surprising when considering ... ...

Abstract	Antiplatelet therapy has demonstrated significant clinical benefit in the treatment of acute coronary syndrome. However, as with any treatment strategy it has been unable to prevent all cardiovascular events. This is far from surprising when considering the complexity of arterial thrombosis and more specifically platelet physiology. This lack of treatment success has provoked the introduction of various diagnostic tests and testing platforms with the intent of guiding and optimizing clinical treatment. Such tests have resulted in the generation of clinical data that suggest suboptimal response to antiplatelet agents such as aspirin and clopidogrel. In the case of both aspirin and clopidogrel, this suboptimal response has been termed resistance. Drug resistance would imply a lack of pharmacological response that has not been specifically investigated in many of the clinical studies performed to date. Rather, the term resistance has been used to describe various facets of platelet activation and aggregation relative to the testing method. Many of these measured parameters are not addressed in the therapeutic intent of the antiplatelet drug in question.
MeSH term(s)	Anti-Inflammatory Agents/adverse effects ; Anti-Inflammatory Agents/therapeutic use ; Aspirin/adverse effects ; Aspirin/therapeutic use ; Coronary Disease/drug therapy ; Drug Monitoring/methods ; Humans ; Platelet Aggregation Inhibitors/adverse effects ; Platelet Aggregation Inhibitors/therapeutic use ; Risk Factors ; Ticlopidine/adverse effects ; Ticlopidine/analogs & derivatives ; Ticlopidine/therapeutic use
Chemical Substances	Anti-Inflammatory Agents ; Platelet Aggregation Inhibitors ; clopidogrel (A74586SNO7) ; Ticlopidine (OM90ZUW7M1) ; Aspirin (R16CO5Y76E)
Language	English
Publishing date	2009-08
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	801512-0
ISSN	0720-9355
ISSN	0720-9355
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Article: Simulation of temperature, stress and microstructure fields during laser deposition of Ti-6Al-4V.

Ghosh, Supriyo / McReynolds, Kevin / Guyer, Jonathan E / Banerjee, Dilip

Modelling and simulation in materials science and engineering

2020 Volume 26, Issue 7

Abstract: We study the evolution of prior ... ...

Abstract	We study the evolution of prior columnar
Language	English
Publishing date	2020-08-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2001737-6
ISSN	1361-651X ; 0965-0393
ISSN (online)	1361-651X
ISSN	0965-0393
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Article ; Online: Demographic and contextual factors as moderators of the relationship between pet ownership and health.

Mueller, Megan K / King, Erin K / Callina, Kristina / Dowling-Guyer, Seana / McCobb, Emily

Health psychology and behavioral medicine

2021 Volume 9, Issue 1, Page(s) 701–723

Abstract: Objective: Companion animals are an important feature of the family system, and human-animal interaction is increasingly being recognized as an important social determinant of health. However, there is a need for more nuanced assessment of not only who ... ...

Abstract	Objective: Companion animals are an important feature of the family system, and human-animal interaction is increasingly being recognized as an important social determinant of health. However, there is a need for more nuanced assessment of not only who owns pets, but how pet ownership is related to various health outcomes, and which sociodemographic and contextual factors moderate these associations. Design: Secondary analysis of cross-sectional data collected from an online, probability-based panel to generate a nationally representative sample of adults in the United States ( Results: Results suggested that pet owners are systematically different from non-pet owners on a number of key demographic and contextual characteristics, and these differences vary somewhat when looking at dog owners and cat owners. When controlling for individual and family-level covariates, pet ownership was not associated with overall health status or Body Mass Index, but dog ownership was associated with higher levels of physical activity. Pet ownership was associated with higher odds of having an anxiety disorder with gender moderating this relationship, but this association was not present for dog or cat owners, suggesting this relationship is limited to other types of pets. Higher odds of depression were associated with pet ownership (for both dog and cat owners), with employment status significantly moderating the relationship between dog ownership status and depression. Conclusions: These findings suggest that pet ownership is a complex and context specific phenomenon. Future research should carefully consider and control for sociodemographic predictors and use measurement and analysis approaches sensitive to the variations in human-animal relationships to fully understand how pets contribute to individual and family health and well-being.
Language	English
Publishing date	2021-08-06
Publishing country	England
Document type	Journal Article
ZDB-ID	2720684-1
ISSN	2164-2850 ; 2164-2850
ISSN (online)	2164-2850
ISSN	2164-2850
DOI	10.1080/21642850.2021.1963254
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Article: A study of medical students and physicians referred for learning disabilities.

Banks, S R / Guyer, B P / Guyer, K E

Annals of dyslexia

2013 Volume 45, Issue 1, Page(s) 233–245

Abstract: This study presents descriptive data on 86 medical students and physicians, referred for testing to determine the presence and type of learning problems. The major results indicate that most subjects had either a learning disability or attention deficit ... ...

Abstract	This study presents descriptive data on 86 medical students and physicians, referred for testing to determine the presence and type of learning problems. The major results indicate that most subjects had either a learning disability or attention deficit hyperactivity disorder (ADHD). Twenty-one subjects had a reading learning disability (LD); 21 subjects had a potential visual/spatial learning problem; 10 subjects had ADHD; 15 subjects had both a reading disability and ADHD; and 19 subjects had no detectable problem. Subtest analysis or WAIS-R scores indicated that sequential information processing may be the major difficulty for this sample.
Language	English
Publishing date	2013-11-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	11939-8
ISSN	1934-7243 ; 0736-9387
ISSN (online)	1934-7243
ISSN	0736-9387
DOI	10.1007/BF02648220
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