LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 67

Search options

  1. Article ; Online: Response to Correspondence re: Live birth per embryo transfer with next generation sequencing preimplantation genetic testing: an analysis of 26,107 cycles.

    Sarkar, Papri / Imudia, Anthony N

    Systems biology in reproductive medicine

    2023  Volume 69, Issue 5, Page(s) 396–397

    MeSH term(s) Pregnancy ; Female ; Humans ; Live Birth ; High-Throughput Nucleotide Sequencing ; Embryo Transfer ; Genetic Testing
    Language English
    Publishing date 2023-11-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2417234-0
    ISSN 1939-6376 ; 1939-6368
    ISSN (online) 1939-6376
    ISSN 1939-6368
    DOI 10.1080/19396368.2023.2261587
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1377: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Good and uninterrupted sleep may be better for eggs.

    Bulka, Catherine M / Mathyk, Begum Aydogan / Imudia, Anthony N

    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

    2024  Volume 20, Issue 1, Page(s) 1–2

    MeSH term(s) Humans ; Sleep ; Time Factors ; Anticoagulants ; Atrial Fibrillation
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2024-03-21
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2397213-0
    ISSN 1550-9397 ; 1550-9389
    ISSN (online) 1550-9397
    ISSN 1550-9389
    DOI 10.5664/jcsm.10920
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6590: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: The effect of trophectoderm biopsy for preimplantation genetic testing on fetal birth weight and preterm delivery.

    Sarkar, Papri / New, Erika P / Jindal, Sangita / Tanner, Jean P / Imudia, Anthony N

    Minerva obstetrics and gynecology

    2023  

    Abstract: Background: Preimplantation genetic testing for aneuploidy (PGT-A) is used as part of in-vitro-fertilization (IVF) to assist in selection of euploid embryos, which involves performing trophectoderm biopsy. The effect of possible trauma caused by biopsy ... ...

    Abstract Background: Preimplantation genetic testing for aneuploidy (PGT-A) is used as part of in-vitro-fertilization (IVF) to assist in selection of euploid embryos, which involves performing trophectoderm biopsy. The effect of possible trauma caused by biopsy and the implication on pregnancy is unknown. Hence, the objective of the study was to determine if embryo biopsy for PGT-A affects birth weight or preterm birth rate.
    Methods: Using National Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) data, we identified 6352 cycles which had single embryo transfer (SET) and a singleton live birth following frozen embryo transfer (FET) between 2014 and 2015.
    Results: From the initial cohort of 25,121 fresh stimulation cycles, 6352 cycles were included who had a singleton live birth following FET. A total of 3482 (54.8%) had PGT-A confirmed euploid embryos and 2870 (45.2%) had embryos selected based on morphology for transfer. No difference in birthweight (g) was noted when FET was performed using PGT-A confirmed euploid embryos as compared to non-tested morphologically selected embryos (3370.7 vs. 3354.5, adjusted regression coefficient 11.4; 95% CI: -12.6; 35.3). As compared to morphologically selected embryos, performance of PGT-A did not increase the risk of small for gestation age (SGA) (3.9% vs. 4.1%, OR: 1.13; 95% CI: 0.86-1.50), low birth weight (LBW) (<2500 g but ≥1500 g) (5.8% vs. 5.5%, OR: 0.90; 95% CI: 0.66-1.21), or very low birthweight (<1500 g) (1.3% vs. 1.0%, OR: 0.44; 95% CI: 0.44 (0.18-1.10). There was no increased risk of preterm birth (PTB) associated with pregnancy resulting from PGT-A embryos vs. non PGT-A embryos (15.8% vs. 16.4%, OR: 0.94; 95% CI: 0.81-1.09).
    Conclusions: In our study, trophectoderm biopsy for PGT-A did not increase the risk of SGA, LBW or PTB in IVF pregnancies.
    Language English
    Publishing date 2023-01-16
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062815-5
    ISSN 2724-6450
    ISSN (online) 2724-6450
    DOI 10.23736/S2724-606X.22.05196-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Um I Zs.245: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Live birth associated with peak serum estradiol levels in letrozole intrauterine insemination cycles.

    New, Erika P / Kodama, Samantha / Devine, Kate / Jahandideh, Samad / Imudia, Anthony N / Plosker, Shayne M

    Fertility and sterility

    2023  Volume 119, Issue 5, Page(s) 785–791

    Abstract: Objective: To identify whether the serum estradiol (E2) level on the day of human chorionic gonadotropin (hCG) trigger or luteinizing hormone (LH) surge (hCG-LH) was associated with the live birth rate (LBR) during ovulation induction (OI) or controlled ...

    Abstract Objective: To identify whether the serum estradiol (E2) level on the day of human chorionic gonadotropin (hCG) trigger or luteinizing hormone (LH) surge (hCG-LH) was associated with the live birth rate (LBR) during ovulation induction (OI) or controlled ovarian hyperstimulation with letrozole followed by intrauterine insemination (IUI).
    Design: Retrospective cohort study.
    Setting: Large, multicenter private practice.
    Patient(s): A total of 2,368 OI-IUI cycles in patients treated with letrozole followed by IUI were evaluated from January 1, 2014, to July 31, 2019.
    Intervention(s): Ovulation induction with letrozole, followed by autologous IUI.
    Main outcome measure(s): The primary outcome measure was the LBR as a function of the serum E2 level at the time of hCG administration or LH surge, adjusting for age, body mass index, the largest follicle diameter, and the number of follicles ≥14 mm in diameter. The clinical pregnancy rate as a function of the E2 level, pregnancy rate as a function of the lead follicle diameter, and pregnancy loss rates were the secondary outcome variables.
    Result(s): A total of 2,368 cycles met the inclusion criteria. Outcomes were evaluated at the 25th (E2 level, 110 pg/mL), 50th (157 pg/mL), 75th (225 pg/mL), and 90th (319 pg/mL) percentiles. The LBRs ranged from 9.4% to 11.1% in the lower E2 cohorts and from 12.5% to 13.5% in the higher E2 cohorts. The LBR was significantly greater in the cohort of women with higher E2 levels in all percentile comparisons except for the 90th percentile. The mean periovulatory follicle diameter of ≥20 or <20 mm was not independently associated with the LBR or clinical pregnancy rate, despite a significantly higher mean E2 level in the larger follicle group.
    Conclusion(s): In letrozole OI cycles followed by IUI, lower LBRs and clinical pregnancy rates were found in women with lower E2 levels than in those with higher E2 levels at the 25th, 50th, and 75th percentile E2 level quartiles. Where possible, delaying hCG trigger until the E2 level increases after aromatase inhibition and approaches the physiologic periovulatory level may improve the pregnancy rates with letrozole followed by IUI.
    MeSH term(s) Pregnancy ; Humans ; Female ; Letrozole ; Live Birth ; Retrospective Studies ; Luteinizing Hormone ; Pregnancy Rate ; Chorionic Gonadotropin ; Ovulation Induction ; Estradiol ; Insemination ; Insemination, Artificial
    Chemical Substances Letrozole (7LKK855W8I) ; Luteinizing Hormone (9002-67-9) ; Chorionic Gonadotropin ; Estradiol (4TI98Z838E)
    Language English
    Publishing date 2023-01-10
    Publishing country United States
    Document type Multicenter Study ; Journal Article
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2023.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 73: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Oocyte Retrieval in Asymptomatic Patients Positive for SARS-CoV-2.

    Akers, Allison / New, Erika P / Plosker, Shayne / Silva, Celso P / Sprague, Rachel / Imudia, Anthony N

    Case reports in obstetrics and gynecology

    2022  Volume 2022, Page(s) 3107747

    Abstract: Objective: To report two cases of oocyte retrieval performed in asymptomatic SARS-CoV-2-positive patients.: Design: Case report. : Results: Both patients underwent successful oocyte retrieval procedures without developing symptoms or complications ...

    Abstract Objective: To report two cases of oocyte retrieval performed in asymptomatic SARS-CoV-2-positive patients.
    Design: Case report.
    Results: Both patients underwent successful oocyte retrieval procedures without developing symptoms or complications from COVID-19. No staff members that cared for these patients developed symptoms of COVID-19.
    Conclusion: Worsening fertility outcomes and potential for psychological and financial burdens to the patient must be balanced with risk of perioperative complications in patients testing positive for SARS-CoV-2. As we continue to provide fertility care in a world with COVID-19, appropriate risk mitigation strategies should be implemented to minimize exposure to SARS-CoV-2.
    Language English
    Publishing date 2022-08-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2627654-9
    ISSN 2090-6692 ; 2090-6684
    ISSN (online) 2090-6692
    ISSN 2090-6684
    DOI 10.1155/2022/3107747
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Live birth per embryo transfer with next generation sequencing preimplantation genetic testing: an analysis of 26,107 cycles.

    Sarkar, Papri / New, Erika P / Sprague, Rachel G / Stillman, Robert / Widra, Eric / Jahandideh, Samad / Devine, Kate / Imudia, Anthony N

    Systems biology in reproductive medicine

    2023  Volume 69, Issue 5, Page(s) 379–386

    Abstract: The technique and platform used for preimplantation genetic testing for aneuploidy (PGT-A) have undergone significant changes over time. The contemporary technique utilizes trophectoderm biopsy followed by next-generation sequencing (NGS). The goal of ... ...

    Abstract The technique and platform used for preimplantation genetic testing for aneuploidy (PGT-A) have undergone significant changes over time. The contemporary technique utilizes trophectoderm biopsy followed by next-generation sequencing (NGS). The goal of this study was to explore the role of PGT-A using NGS technique exclusively in contemporary
    MeSH term(s) Pregnancy ; Humans ; Female ; Adult ; Live Birth ; Preimplantation Diagnosis/methods ; Retrospective Studies ; High-Throughput Nucleotide Sequencing ; Embryo Transfer/methods ; Fertilization in Vitro ; Genetic Testing/methods ; Aneuploidy ; Blastocyst
    Language English
    Publishing date 2023-06-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2417234-0
    ISSN 1939-6376 ; 1939-6368
    ISSN (online) 1939-6376
    ISSN 1939-6368
    DOI 10.1080/19396368.2023.2208253
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1377: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: High estradiol levels in fresh embryo transfer cycles are not associated with detrimental impact on birth outcomes.

    Lersten, Ivy L / Grau, Laura / Jahandideh, Samad / Devine, Kate / Zalles, Laura / Plosker, Shayne M / Imudia, Anthony N / Hoyos, Luis R / Uhler, Meike L / Homer, Michael / Roeca, Cassandra / Sammel, Mary D / Polotsky, Alex J

    Journal of assisted reproduction and genetics

    2024  Volume 41, Issue 4, Page(s) 893–902

    Abstract: Purpose: There is an unclear relationship between estradiol levels and fresh embryo transfer (ET) outcomes. We determined the relationship between estradiol on the day of trigger, in fresh ET cycles without premature progesterone elevation, and good ... ...

    Abstract Purpose: There is an unclear relationship between estradiol levels and fresh embryo transfer (ET) outcomes. We determined the relationship between estradiol on the day of trigger, in fresh ET cycles without premature progesterone elevation, and good birth outcomes (GBO).
    Methods: We identified autologous fresh ET cycles from 2015 to 2021 at multiple clinics in the USA. Patients with recurrent pregnancy loss, uterine factor, and elevated progesterone on the day of trigger (progesterone > 2 ng/mL or 3-day area under the curve > 4.5 ng/mL) were excluded. The primary outcome was GBO (singleton, term, live birth with appropriate weight). Log-binomial generalized estimating equations determined the likelihood of outcomes.
    Results: Of 17,608 fresh ET cycles, 5025 (29%) yielded GBO. Cycles with estradiol
    Conclusion: In fresh ET cycles, higher estradiol levels were associated with an increased prevalence of GBO until estradiol 2000-2999 pg/mL, thereafter plateauing. In fresh ET candidates, elevated estradiol levels should not preclude eligibility though premature progesterone rise, and risk of ovarian hyperstimulation syndrome must still be considered.
    MeSH term(s) Humans ; Female ; Estradiol/blood ; Embryo Transfer/methods ; Pregnancy ; Adult ; Fertilization in Vitro/methods ; Ovulation Induction/methods ; Pregnancy Rate ; Progesterone/blood ; Live Birth/epidemiology ; Pregnancy Outcome
    Chemical Substances Estradiol (4TI98Z838E) ; Progesterone (4G7DS2Q64Y)
    Language English
    Publishing date 2024-04-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1112577-9
    ISSN 1573-7330 ; 1058-0468
    ISSN (online) 1573-7330
    ISSN 1058-0468
    DOI 10.1007/s10815-024-03062-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1985: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Contemporary management of adnexa at the time of benign hysterectomy: a review of the literature.

    Tamhane, Nupur / Imudia, Anthony N / Mikhail, Emad

    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

    2019  Volume 39, Issue 7, Page(s) 896–902

    Abstract: Ovarian cancer is the leading cause of Gynecological cancer related mortality in the USA. Due to the absence of an effective screening method, concomitant adnexal management during hysterectomy or other pelvic surgeries is a prime consideration. ... ...

    Abstract Ovarian cancer is the leading cause of Gynecological cancer related mortality in the USA. Due to the absence of an effective screening method, concomitant adnexal management during hysterectomy or other pelvic surgeries is a prime consideration. Bilateral salpingo-oophorectomy (BSO) offers the benefit of eliminating the risk of ovarian cancer however it leads to surgical menopause with unfavourable overall health outcomes. With the latest verification that serous tubal intraepithelial carcinoma detected in the distal fimbriated end of the fallopian tube being the precursor of Type 2 ovarian cancers, there is an increased trend of performing bilateral salpingectomy (BS) as a risk reduction strategy for ovarian cancer. Women with a high risk for ovarian cancer due to familial or genetic mutations and those diagnosed with endometriosis need particular attention while planning adnexal management during hysterectomy. Physician and patient's shared decision-making regarding adnexal management during benign hysterectomy taking into consideration the route of hysterectomy is an important portion of pre-operative planning. The objective of this article is to understand the current trends of BSO and BS during benign hysterectomy and appreciate the pros and cons to aid in pre-operative counselling of patients.
    MeSH term(s) Adnexa Uteri/surgery ; Contraindications, Procedure ; Female ; Humans ; Hysterectomy/methods ; Ovariectomy ; Salpingectomy
    Language English
    Publishing date 2019-07-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 604639-3
    ISSN 1364-6893 ; 0144-3615
    ISSN (online) 1364-6893
    ISSN 0144-3615
    DOI 10.1080/01443615.2019.1581747
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 2461: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: Improving the fellowship interview experience for reproductive endocrinology and infertility candidates: a survey.

    New, Erika P / Sarkar, Papri / Alvero, Ruben J / Imudia, Anthony N

    F&S reports

    2020  Volume 1, Issue 1, Page(s) 37–42

    Abstract: ... used to interview. About 68.1% (n = 30) missed an opportunity to interview at a program they were ... could not attend due to geographic location, and cost was too high. About 72% (n = 31) traveled to the same ...

    Abstract Objective: To collect data on the current reproductive endocrinology and infertility (REI) fellowship interview process so that it may be improved in the future.
    Design: Web-based cross-sectional survey. In addition, fellowship program directors and coordinators were contacted by e-mail.
    Setting: Survey data were collected after completion of the 2018 REI fellowship interview season.
    Patients: Not applicable.
    Interventions: None.
    Main outcome measures: Number of days used for interviews, missed opportunities to interview, frequency of travel to the same city, average money spent, recommendations for how the interview process could be improved.
    Results: There were 44 survey respondents. The mean number of interviews attended was 12.6 (range, 1-22). On average 13.4 (0-30) days off work were used to interview. About 68.1% (n = 30) missed an opportunity to interview at a program they were interested in. The most common reasons were the interview date was the same day as another interview, could not attend due to geographic location, and cost was too high. About 72% (n = 31) traveled to the same city more than once for an interview. The average cost per interview was $478 (range, $200-$1,000) and average cost per interview season was $5,660 (range, $900-$15,000). Fellowship program data were available from 43 of 48 programs contacted. The number of dates that had conflicting interviews scheduled were 26.
    Conclusions: These data highlight the need to coordinate the REI fellowship recruitment process between programs to reduce conflicting interview dates and mitigate costs to applicants. Based on these results, a concrete action plan is presented.
    Language English
    Publishing date 2020-04-14
    Publishing country United States
    Document type Journal Article
    ISSN 2666-3341
    ISSN (online) 2666-3341
    DOI 10.1016/j.xfre.2020.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: The Past, Present, and Future of Preimplantation Genetic Testing.

    Imudia, Anthony N / Plosker, Shayne

    Clinics in laboratory medicine

    2016  Volume 36, Issue 2, Page(s) 385–399

    Abstract: Preimplantation genetic testing (PGT) of oocytes and embryos is the earliest form of prenatal testing. PGT requires in vitro fertilization for embryo creation. In the past 25 years, the use of PGT has increased dramatically. The indications of PGT ... ...

    Abstract Preimplantation genetic testing (PGT) of oocytes and embryos is the earliest form of prenatal testing. PGT requires in vitro fertilization for embryo creation. In the past 25 years, the use of PGT has increased dramatically. The indications of PGT include identification of embryos harboring single-gene disorders, chromosomal structural abnormalities, chromosomal numeric abnormalities, and mitochondrial disorders; gender selection; and identifying unaffected, HLA-matched embryos to permit the creation of a savior sibling. PGT is not without risks, limitations, or ethical controversies. This review discusses the techniques and clinical applications of different forms of PGT and the debate surrounding its associated uncertainty and expanded use.
    MeSH term(s) Aneuploidy ; Female ; Genetic Diseases, Inborn/diagnosis ; History, 20th Century ; History, 21st Century ; Humans ; Pregnancy ; Preimplantation Diagnosis/history ; Preimplantation Diagnosis/methods ; Preimplantation Diagnosis/trends
    Language English
    Publishing date 2016-06
    Publishing country United States
    Document type Historical Article ; Journal Article ; Review
    ZDB-ID 604580-7
    ISSN 1557-9832 ; 0272-2712
    ISSN (online) 1557-9832
    ISSN 0272-2712
    DOI 10.1016/j.cll.2016.01.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1695: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top