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  1. Article ; Online: Evaluation of canine and feline leukocyte differential counts obtained with the scil vCell 5 compared to the Advia 2120 hematology analyzer and a manual method.

    Zelmer, Kim-Lina Charlotte / Moritz, Andreas / Bauer, Natali

    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

    2023  Volume 35, Issue 6, Page(s) 679–697

    Abstract: The vCell 5 (scil Animal Care), a point-of-care hematology analyzer (POCA), was recently introduced to veterinary laboratories. This laser- and impedance-based analyzer is capable of providing a CBC with 5-part WBC differential count (Diff) along with ... ...

    Abstract The vCell 5 (scil Animal Care), a point-of-care hematology analyzer (POCA), was recently introduced to veterinary laboratories. This laser- and impedance-based analyzer is capable of providing a CBC with 5-part WBC differential count (Diff) along with WBC cytograms and flags serving as interpretation aids for numerical results. We compared the scil POCA-Diff to reference methods (i.e., manual differential count, Advia 2120 hematology analyzer [Siemens]) for canine and feline blood samples and considered WBC cytograms and flags. Total observed error (TEo), calculated from CV and bias%, was compared to total allowable error (TEa). Data were analyzed before and after a review process (exclusion of flagged and samples with invalid cytograms). For both species, correlation was good-to-excellent (
    MeSH term(s) Cats ; Dogs ; Animals ; Cat Diseases ; Sensitivity and Specificity ; Dog Diseases ; Leukocyte Count/veterinary ; Hematology ; Neutrophils ; Reproducibility of Results
    Chemical Substances ethyl 2-(5-(4-chlorophenyl)pentyl)oxiran-2-carboxylate (87XB8J7FLL)
    Language English
    Publishing date 2023-08-23
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 287603-6
    ISSN 1943-4936 ; 1040-6387
    ISSN (online) 1943-4936
    ISSN 1040-6387
    DOI 10.1177/10406387231187899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Conference proceedings: [No title information]

    Zelmer, KC / Moritz, A / Bauer, N

    Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere

    2023  Volume 51, Issue 01

    Event/congress 31. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab) - Teil 1: Vorträge, online, 2023-02-03
    Language German
    Publishing date 2023-02-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2567-5842 ; 1434-1239
    ISSN (online) 2567-5842
    ISSN 1434-1239
    DOI 10.1055/s-0043-1760799
    Database Thieme publisher's database

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  3. Article ; Online: Evaluation of the scil vCell 5, a novel laser- and impedance-based point-of-care hematology analyzer, for use in dogs and cats.

    Zelmer, Kim-Lina Charlotte / Bauer, Natali / Moritz, Andreas

    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

    2022  Volume 34, Issue 3, Page(s) 504–517

    Abstract: A novel laser- and impedance-based point-of-care hematology analyzer (POCA), the vCell 5 (scil Animal Care), providing a complete blood count with 5-part leukocyte differential count has recently been introduced to veterinary laboratories. We evaluated ... ...

    Abstract A novel laser- and impedance-based point-of-care hematology analyzer (POCA), the vCell 5 (scil Animal Care), providing a complete blood count with 5-part leukocyte differential count has recently been introduced to veterinary laboratories. We evaluated the analyzer for use in dogs and cats including method comparison and assessment of linearity, carryover, and precision. Fresh blood samples from 192 healthy and diseased dogs and 159 cats were analyzed, and results were compared to reference methods (i.e., microhematocrit [PCV], Advia 2120 hematology analyzer). Total observed error (TEo) was calculated from CV, obtained at 3 concentrations, and bias%, and compared to total allowable error (TEa). For both species, excellent correlation (r
    MeSH term(s) Animals ; Blood Cell Count/veterinary ; Cat Diseases/diagnosis ; Cats ; Dog Diseases/diagnosis ; Dogs ; Electric Impedance ; Hematology ; Hemoglobins ; Lasers ; Point-of-Care Systems ; Reproducibility of Results
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2022-03-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 287603-6
    ISSN 1943-4936 ; 1040-6387
    ISSN (online) 1943-4936
    ISSN 1040-6387
    DOI 10.1177/10406387221083621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Conference proceedings: [No title information]

    Feuerbach, A / Bauer, N / Moritz, A

    Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere

    2022  Volume 50, Issue 01

    Event/congress 30. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab) - Teil 1: Vorträge, Online-Tagung, 2022-01-28
    Language German
    Publishing date 2022-03-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2567-5842 ; 1434-1239
    ISSN (online) 2567-5842
    ISSN 1434-1239
    DOI 10.1055/s-0041-1741155
    Database Thieme publisher's database

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  5. Article ; Conference proceedings: [No title information]

    Proksch, AL / Bauer, N / Langenstein, J / Schneider, M A / Moritz, A

    Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere

    2023  Volume 51, Issue 01

    Event/congress 31. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab) - Teil 1: Vorträge, online, 2023-02-03
    Language German
    Publishing date 2023-02-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2567-5842 ; 1434-1239
    ISSN (online) 2567-5842
    ISSN 1434-1239
    DOI 10.1055/s-0043-1760805
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  6. Article ; Conference proceedings: [No title information]

    Klemm, I / Dreller, V / Staudacher, G / Bauer, N / Moritz, A / Proksch, A-L

    Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere

    2023  Volume 51, Issue 01

    Event/congress 31. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab) - Teil 1: Vorträge, online, 2023-02-03
    Language German
    Publishing date 2023-02-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2567-5842 ; 1434-1239
    ISSN (online) 2567-5842
    ISSN 1434-1239
    DOI 10.1055/s-0043-1760806
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  7. Article ; Online: Evaluation of reticulocyte hemoglobin content (RETIC-HGB) for the diagnosis of iron-limited erythropoiesis in cats.

    Keiner, Miriam / Fuchs, Jannika / Bauer, Natali / Moritz, Andreas

    Veterinary clinical pathology

    2021  Volume 49, Issue 4, Page(s) 557–566

    Abstract: Background: Decreased reticulocyte hemoglobin content (CHr) (Siemens ADVIA 2120) reflects iron-limited erythropoiesis (ILE). RETIC-HGB (IDEXX ProCyte Dx) is a novel marker of ILE for veterinary use.: Objectives: We aimed to evaluate reference ... ...

    Abstract Background: Decreased reticulocyte hemoglobin content (CHr) (Siemens ADVIA 2120) reflects iron-limited erythropoiesis (ILE). RETIC-HGB (IDEXX ProCyte Dx) is a novel marker of ILE for veterinary use.
    Objectives: We aimed to evaluate reference intervals (RIs) and the utility of RETIC-HGB and CHr in the diagnosis of feline ILE.
    Materials and methods: RIs were established in 59 healthy cats. Intra-assay coefficients of variation (CVs) and correlations between RETIC-HGB and CHr were assessed. Two hundred and seventy-five cats were classified as having ILE or not based on low plasma iron or low transferrin saturation along with anemia and/or altered RBC indices. CHr, RETIC-HGB, and serum amyloid A (SAA) were compared between the groups. The sensitivity and specificity of RETIC-HGB and CHr to diagnose ILE were analyzed to determine the RI lower limits.
    Results: RIs for RETIC-HGB and CHr were 12.5-18.0 and 14.0-19.9 pg, respectively. The CV was 3% for both variables. RETIC-HGB and CHr were moderately correlated (r
    Conclusions: ILE was characterized by decreased CHr and RETIC-HGB; however, sensitivity was low. The moderate correlation between RETIC-HGB and CHr is likely due to species differences and different methodology.
    MeSH term(s) Anemia, Iron-Deficiency/blood ; Anemia, Iron-Deficiency/diagnosis ; Anemia, Iron-Deficiency/veterinary ; Animals ; Case-Control Studies ; Cat Diseases/blood ; Cat Diseases/diagnosis ; Cats ; Erythrocyte Count/veterinary ; Erythropoiesis ; Female ; Hematocrit/veterinary ; Hemoglobins/analysis ; Male ; Reticulocytes/chemistry
    Chemical Substances Hemoglobins
    Language English
    Publishing date 2021-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2114702-4
    ISSN 1939-165X ; 0275-6382
    ISSN (online) 1939-165X
    ISSN 0275-6382
    DOI 10.1111/vcp.12925
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Conference proceedings: [No title information]

    Weiß, M / Kleber, K / Moritz, A / Gerwing, M / Bauer, N

    Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere

    2022  Volume 50, Issue 01

    Event/congress 30. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab) - Teil 1: Vorträge, Online-Tagung, 2022-01-28
    Language German
    Publishing date 2022-03-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2567-5842 ; 1434-1239
    ISSN (online) 2567-5842
    ISSN 1434-1239
    DOI 10.1055/s-0041-1741154
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  9. Article ; Conference proceedings: Vergleich zweier in-house-Kultursysteme für die Diagnostik der kaninen bakteriellen Zystitis

    Dreller, V. / Klemm, I. / Aurich, S. / Hoffmann, C. / Prenger-Berninghoff, E. / Bauer, N. / Moritz, A. / Proksch, A. L.

    Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere

    2024  Volume 52, Issue 01

    Event/congress 32. Jahrestagung der FG „Innere Medizin und klinische Labordiagnostik“ der DVG (InnLab) - Teil 1: Vorträge , Hannover, 2024-02-02
    Language German
    Publishing date 2024-02-01
    Publisher Georg Thieme Verlag
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ISSN 2567-5842 ; 1434-1239
    ISSN (online) 2567-5842
    ISSN 1434-1239
    DOI 10.1055/s-0044-1779645
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  10. Article ; Online: Causality in transcription and genome folding: Insights from X inactivation.

    Bauer, Moritz / Payer, Bernhard / Filion, Guillaume J

    BioEssays : news and reviews in molecular, cellular and developmental biology

    2022  Volume 44, Issue 10, Page(s) e2200105

    Abstract: The spatial organization of genomes is becoming increasingly understood. In mammals, where it is most investigated, this organization ties in with transcription, so an important research objective is to understand whether gene activity is a cause or a ... ...

    Abstract The spatial organization of genomes is becoming increasingly understood. In mammals, where it is most investigated, this organization ties in with transcription, so an important research objective is to understand whether gene activity is a cause or a consequence of genome folding in space. In this regard, the phenomena of X-chromosome inactivation and reactivation open a unique window of investigation because of the singularities of the inactive X chromosome. Here we focus on the cause-consequence nexus between genome conformation and transcription and explain how recent results about the structural changes associated with inactivation and reactivation of the X chromosome shed light on this problem.
    MeSH term(s) Animals ; Genome/genetics ; Mammals/genetics ; X Chromosome ; X Chromosome Inactivation/genetics
    Language English
    Publishing date 2022-08-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 50140-2
    ISSN 1521-1878 ; 0265-9247
    ISSN (online) 1521-1878
    ISSN 0265-9247
    DOI 10.1002/bies.202200105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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