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  1. Article ; Online: Editorial: Host immune response and regulation to parasitic infections: therapeutic approaches and defence strategies.

    Siddiqui, Arif Jamal / Adnan, Mohd / Bardakci, Fevzi / Molehin, Adebayo James

    Frontiers in immunology

    2023  Volume 14, Page(s) 1215086

    MeSH term(s) Animals ; Parasitic Diseases ; Parasites ; Immunity
    Language English
    Publishing date 2023-05-24
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2023.1215086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Optimization and Characterization of Phenolic Extraction Conditions and Antioxidant Activity Evaluation of

    Begum, Syeda Nurunnesa / Hossain, Mobarok / Adnan, Md / Rahaman, Chowdhury Habibur / Reza, Arif

    Plants (Basel, Switzerland)

    2023  Volume 12, Issue 22

    Abstract: The presence of high levels of secondary metabolites in medicinal plants can significantly influence the progress of drug development. Here, we aimed to maximize phenolic extraction ... ...

    Abstract The presence of high levels of secondary metabolites in medicinal plants can significantly influence the progress of drug development. Here, we aimed to maximize phenolic extraction from
    Language English
    Publishing date 2023-11-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2704341-1
    ISSN 2223-7747
    ISSN 2223-7747
    DOI 10.3390/plants12223902
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Molecular Characterization of Hard Ticks Infesting Camels in the Northern Region of Saudi Arabia Using the Barcoding Gene, Mitochondrial

    Bardakci, Fevzi / Al-Subaie, Sarah Hilan Mohammed / Badraoui, Riadh / Adnan, Mohd / Siddiqui, Arif Jamal

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 7

    Abstract: The present study aimed to molecularly identify and characterize the hard ticks infesting camels from the northern region (Ha'il province) of Saudi Arabia using the mitochondrial barcoding ... ...

    Abstract The present study aimed to molecularly identify and characterize the hard ticks infesting camels from the northern region (Ha'il province) of Saudi Arabia using the mitochondrial barcoding gene
    Language English
    Publishing date 2023-07-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13071535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Mechanistic insights into MARK4 inhibition by galantamine toward therapeutic targeting of Alzheimer's disease.

    Adnan, Mohd / DasGupta, Debarati / Anwar, Saleha / Shamsi, Anas / Siddiqui, Arif Jamal / Snoussi, Mejdi / Bardakci, Fevzi / Patel, Mitesh / Hassan, Md Imtaiyaz

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1276179

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-09-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1276179
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Glycemic control as the main determinant factor of serum VEGF levels in type 2 diabetes mellitus patients.

    Kurniawan, Liong Boy / Andriany, Rika / Widaningsih, Yuyun / Esa, Tenri / Bahrun, Uleng / Adnan, Endy / Arif, Mansyur

    Romanian journal of internal medicine = Revue roumaine de medecine interne

    2023  Volume 61, Issue 3, Page(s) 135–140

    Abstract: Introduction. ...

    Abstract Introduction.
    MeSH term(s) Humans ; Diabetes Mellitus, Type 2/complications ; Vascular Endothelial Growth Factor A ; Glycated Hemoglobin ; Cross-Sectional Studies ; Glycemic Control ; Blood Glucose/metabolism ; Vascular Endothelial Growth Factors ; Lipids
    Chemical Substances Vascular Endothelial Growth Factor A ; Glycated Hemoglobin ; Blood Glucose ; Vascular Endothelial Growth Factors ; Lipids
    Language English
    Publishing date 2023-04-05
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2015966-3
    ISSN 2501-062X ; 0035-3973 ; 1582-3296
    ISSN (online) 2501-062X
    ISSN 0035-3973 ; 1582-3296
    DOI 10.2478/rjim-2023-0009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Preparation and characterization of single perovskite microplates and its sunlight assisted photodecolorization activity, validated by response surface methodology.

    Nawaz, Arif / Naz, Irum / Atif, Muhammad / Khan, Adnan / Ali, Nisar

    Chemosphere

    2023  Volume 334, Page(s) 138923

    Abstract: Perovskites overtaking simple metal oxides as solar light harvesting material due to their excellent photocatalytic efficiency and superior stability. An efficient visible light responsive, ... ...

    Abstract Perovskites overtaking simple metal oxides as solar light harvesting material due to their excellent photocatalytic efficiency and superior stability. An efficient visible light responsive, K
    MeSH term(s) Sunlight ; Spectroscopy, Fourier Transform Infrared ; Oxides/chemistry ; Light ; Catalysis ; Methylene Blue/chemistry
    Chemical Substances perovskite (12194-71-7) ; Oxides ; Methylene Blue (T42P99266K)
    Language English
    Publishing date 2023-05-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 120089-6
    ISSN 1879-1298 ; 0045-6535 ; 0366-7111
    ISSN (online) 1879-1298
    ISSN 0045-6535 ; 0366-7111
    DOI 10.1016/j.chemosphere.2023.138923
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Elucidation of Molecular Interactions Between Drug-Polymer in Amorphous Solid Dispersion by a Computational Approach Using Molecular Dynamics Simulations.

    Aulifa, Diah Lia / Al Shofwan, Adnan Aly / Megantara, Sandra / Fakih, Taufik Muhammad / Budiman, Arif

    Advances and applications in bioinformatics and chemistry : AABC

    2024  Volume 17, Page(s) 1–19

    Abstract: Introduction: Amorphous drug dispersion is frequently used to enhance the solubility and dissolution of poorly water-soluble drugs, thereby improving their oral bioavailability. The dispersion of these drugs into polymer matrix can inhibit their ... ...

    Abstract Introduction: Amorphous drug dispersion is frequently used to enhance the solubility and dissolution of poorly water-soluble drugs, thereby improving their oral bioavailability. The dispersion of these drugs into polymer matrix can inhibit their recrystallization. The inter-molecular interactions between drug and polymer plays a role in the improvement of the dissolution rate, solubility, and physical stability of drug.
    Aim: This study aims to investigate the formation and interactions of ritonavir (RTV)/poloxamer (PLX) amorphous formulation using a computational approach via molecular dynamics (MD) simulations, which mimicked solvent evaporation and melt-quenching method.
    Methods: TheRoot Mean Square Deviation (RMSD) value, Root Mean Square Fluctuation (RMSF), Radial Distribution Function (RDF), Radius of Gyration (Rg), Solvent Accessible Surface Area (SASA), and hydrogen bond interactions were analyzed to determine interaction mechanisms between RTV and PLX in amorphous solid dispersion.
    Results: The pi-alkyl bonds between RTV and PLX were formed after simulations of solvent evaporation, while the hydrogen bond interactions of RTV-PLX was observed during melt method simulations. These results indicate the successful formulation of amorphous solid dispersion (ASD) from RTV and PLX. The RMSD values obtained from the solvent evaporation, melt-cooling-A, melt-cooling-B, and melt-cooling-C methods were 3.33 Å, 1.97 Å, 1.30 Å, and 1.29 Å, respectively, while the average RMSF values were 2.65 Å, 1.04 Å, 1.05 Å, and 1.07 Å, respectively. This indicates that the suppression of translational motion of RTV from the melt method can be stronger than solvent evaporation caused by the intermolecular interactions of RTV-PLX.
    Conclusion: MD simulations helped in understanding the formation and interaction mechanisms of ASD formulations that were difficult to detect by experimental approaches.
    Language English
    Publishing date 2024-01-23
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494731-3
    ISSN 1178-6949
    ISSN 1178-6949
    DOI 10.2147/AABC.S441628
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: A Critical Review on Human Malaria and Schistosomiasis Vaccines: Current State, Recent Advancements, and Developments.

    Siddiqui, Arif Jamal / Bhardwaj, Jyoti / Saxena, Juhi / Jahan, Sadaf / Snoussi, Mejdi / Bardakci, Fevzi / Badraoui, Riadh / Adnan, Mohd

    Vaccines

    2023  Volume 11, Issue 4

    Abstract: Malaria and schistosomiasis are two major parasitic diseases that remain leading causes of morbidity and mortality worldwide. Co-infections of these two parasites are common in the tropics, where both diseases are endemic. The clinical consequences of ... ...

    Abstract Malaria and schistosomiasis are two major parasitic diseases that remain leading causes of morbidity and mortality worldwide. Co-infections of these two parasites are common in the tropics, where both diseases are endemic. The clinical consequences of schistosomiasis and malaria are determined by a variety of host, parasitic, and environmental variables. Chronic schistosomiasis causes malnutrition and cognitive impairments in children, while malaria can cause fatal acute infections. There are effective drugs available to treat malaria and schistosomiasis. However, the occurrence of allelic polymorphisms and the rapid selection of parasites with genetic mutations can confer reduced susceptibility and lead to the emergence of drug resistance. Moreover, the successful elimination and complete management of these parasites are difficult due to the lack of effective vaccines against
    Language English
    Publishing date 2023-04-04
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2703319-3
    ISSN 2076-393X
    ISSN 2076-393X
    DOI 10.3390/vaccines11040792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Characterization and Process Optimization for Enhanced Production of Polyhydroxybutyrate (PHB)-Based Biodegradable Polymer from

    Adnan, Mohd / Siddiqui, Arif Jamal / Ashraf, Syed Amir / Snoussi, Mejdi / Badraoui, Riadh / Ibrahim, Angum M M / Alreshidi, Mousa / Sachidanandan, Manojkumar / Patel, Mitesh

    Polymers

    2023  Volume 15, Issue 6

    Abstract: In recent years, there has been a growing interest in bio-based degradable plastics as an alternative to synthetic plastic. Polyhyroxybutyrate (PHB) is a macromolecule produced by bacteria as a part of their metabolism. Bacteria accumulate them as ... ...

    Abstract In recent years, there has been a growing interest in bio-based degradable plastics as an alternative to synthetic plastic. Polyhyroxybutyrate (PHB) is a macromolecule produced by bacteria as a part of their metabolism. Bacteria accumulate them as reserve materials when growing under different stress conditions. PHBs can be selected as alternatives for the production of biodegradable plastics because of their fast degradation properties when exposed to natural environmental conditions. Hence, the present study was undertaken in order to isolate the potential PHB-producing bacteria isolated from the municipal solid waste landfill site soil samples collected from the Ha'il region of Saudi Arabia to assess the production of PHB using agro-residues as a carbon source and to evaluate the growth of PHB production. In order to screen the isolates for producing PHB, a dye-based procedure was initially employed. Based on the 16S rRNA analysis of the isolates,
    Language English
    Publishing date 2023-03-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15061407
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Lactobacillus reuteri

    Siddique, Abubakar / Azim, Sara / Ali, Amjad / Adnan, Fazal / Arif, Maryum / Imran, Muhammad / Ganda, Erika / Rahman, Abdur

    Animals : an open access journal from MDPI

    2021  Volume 11, Issue 12

    Abstract: ... Non- ... ...

    Abstract Non-typhoidal
    Language English
    Publishing date 2021-12-01
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani11123435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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