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Article ; Online: Correction: Arce-Huamani et al. Efficacy and Safety of Apixaban versus Dalteparin as a Treatment for Cancer-Associated Venous Thromboembolism: A Systematic Review and Meta-Analysis.

Arce-Huamani, Miguel A / Barboza, Joshuan J / Martínez-Herrera, José Fabián / Torres-Roman, J Smith / Maguiña, Jorge L

2024 Volume 60, Issue 1

Abstract: There was an error in the original publication [ ... ]. ...

Abstract	There was an error in the original publication [...].
Language	English
Publishing date	2024-01-11
Publishing country	Switzerland
Document type	Published Erratum
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina60010134
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Article ; Online: Clinical Features and Outcomes of Triple-Negative Breast Cancer Among Latin American Adolescents and Young Adults Compared to Middle-Aged and Elder Females: A Cohort Analysis Over 15 Years.

Valcarcel, Bryan / Torres-Roman, J Smith / Enriquez-Vera, Daniel / De-la-Cruz-Ku, Gabriel

Journal of adolescent and young adult oncology

2023 Volume 12, Issue 5, Page(s) 625–633

Abstract: Purpose: ...

Abstract	Purpose:
Language	English
Publishing date	2023-02-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2607978-1
ISSN	2156-535X ; 2156-5333
ISSN (online)	2156-535X
ISSN	2156-5333
DOI	10.1089/jayao.2022.0075
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Article ; Online: Use of ivermectin and factors associated with the prevention and/or treatment of COVID-19: a cross-sectional online survey in the province of Chincha, Peru.

Salvador-Carrillo, Jose / Campos-Loza, Luz / Guillen-Carbajal, David / Osada, Jorge / Zevallos, Alejandra / Torres-Roman, J Smith

F1000Research

2024 Volume 12, Page(s) 149

Abstract: Background: Peru has reported one of the highest mortality rates from COVID-19 worldwide. The Chincha province has been one of the most affected regions in Peru and the leading promoter of the use of ivermectin for the treatment of COVID-19. Therefore, ... ...

Abstract	Background: Peru has reported one of the highest mortality rates from COVID-19 worldwide. The Chincha province has been one of the most affected regions in Peru and the leading promoter of the use of ivermectin for the treatment of COVID-19. Therefore, our study aimed to evaluate the frequency of use and factors associated with the use of ivermectin for COVID-19 in Chincha. Methods: A cross-sectional study was conducted during the second wave of COVID-19 in Peru. For statistical analyses, frequencies and percentages were reported. Prevalence ratios (PR) with a 95% confidence interval (CI), and a p-value of 0.05 were used to determine statistical significance. SPSS version 22 (IBM Corp) program was used for the analyses. Results: A total of 432 participants were included in the study. A total of 67.6% (n = 292) of the participants used ivermectin during the COVID-19 pandemic. Of these, 20.20% (n=59) of the people used ivermectin for prophylactic purposes only, while 41.79% (n=122) used it as treatment for COVID-19 only, and 38.01% (n=111) used it for both reasons. The consumption of ivermectin was associated with being 50 years or older (PR:1.27, 95% CI:1.04-1.54), having a technical education level (PR:1.16, 95% CI:1.01-1.34), having had symptoms of COVID-19 with negative/no diagnosis (PR: 1.28, 95% CI: 1.07-1.53) or positive diagnosis (PR:1.38, 95% CI:1.18-1.61), or having had contact with infected people (PR:1.45, 95% CI:1.06-1.98). Conclusions: Most people in Chincha used ivermectin during the second wave of the COVID-19 pandemic. The main factors associated with the use of ivermectin for the prevention/treatment of COVID-19 were age ≥50 years, having a technical education level, having had symptoms with negative/no diagnosis or positive diagnosis, and contact with people infected with SARS-CoV-2.
MeSH term(s)	Humans ; Middle Aged ; COVID-19/epidemiology ; Cross-Sectional Studies ; Ivermectin/therapeutic use ; Peru/epidemiology ; SARS-CoV-2 ; Pandemics/prevention & control
Chemical Substances	Ivermectin (70288-86-7)
Language	English
Publishing date	2024-01-08
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.128675.3
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Article ; Online: Association of healthcare system factors with childhood leukemia mortality in Peru, 2017-2019: A population-based analysis.

Valcarcel, Bryan / Murillo, Franco / Torres-Roman, J Smith

Journal of cancer policy

2021 Volume 29, Page(s) 100288

Abstract: Background: Childhood leukemia mortality is expected to increase in certain developing Latin American countries by 2030. The development of tailored public health interventions could benefit by understanding the role of healthcare system factors. ... ...

Abstract	Background: Childhood leukemia mortality is expected to increase in certain developing Latin American countries by 2030. The development of tailored public health interventions could benefit by understanding the role of healthcare system factors. Therefore, we aimed to evaluate the area-level association of healthcare system factors with leukemia mortality among Peruvian children aged 0-19. Methods: We abstracted province-level death counts from the National Death Registry Information System database between 2017 and 2019. Continuous factors were dichotomized by their median. We fitted multivariate quasi-Poisson regression models for all leukemia and stratifying by subtypes of leukemia. Results: From 2017 to 2019, 755 leukemia deaths were reported. Healthcare system factors associated with mortality varied by leukemia subtype. In lymphoid leukemia, a prolonged travel time to a healthcare facility (RR: 1.26, 95 % CI: 1.01-1.58), a high density of primary care physicians (RR: 1.57, 95 % CI: 1.25-1.97), and a high density of hospitals (RR: 1.64, 95 % CI: 1.23-2.20) were related to mortality. In myeloid leukemia, only a high density of hospitals (RR: 1.76, 95 % CI: 1.06-3.01) was associated with mortality. Conclusion: The province-level healthcare system factors related to mortality varied by leukemia subtype on children aged 0-19. The association found in provinces with a high density of primary care physicians or hospitals suggests a disparity in case identification between the areas with better and worse healthcare capacity. Higher mortality rates in provinces with prolonged travel time to a healthcare facility indicate a centralization of cancer-directed treatment and difficulties with its distribution. Policy summary: To prevent childhood leukemia deaths, we highlight the need to strengthen the public health system through policies that enhance the distribution of leukemia treatment to locations far away from medical centers. Strengthening the supply, distribution, and adherence to leukemia cancer-directed treatment should be a public health priority for Peru.
MeSH term(s)	Child ; Delivery of Health Care ; Hospitals ; Humans ; Leukemia ; Peru/epidemiology ; Registries
Language	English
Publishing date	2021-05-29
Publishing country	England
Document type	Journal Article
ISSN	2213-5383
ISSN (online)	2213-5383
DOI	10.1016/j.jcpo.2021.100288
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Article ; Online: Efficacy and Safety of Apixaban versus Dalteparin as a Treatment for Cancer-Associated Venous Thromboembolism: A Systematic Review and Meta-Analysis.

Arce-Huamani, Miguel A / Barboza, Joshuan J / Martínez-Herrera, José Fabián / Torres-Roman, J Smith / Maguiña, Jorge L

Medicina (Kaunas, Lithuania)

2023 Volume 59, Issue 10

Abstract: Background and ... ...

Abstract	Background and Objectives
MeSH term(s)	Humans ; Dalteparin/adverse effects ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/etiology ; Anticoagulants/adverse effects ; Hemorrhage/chemically induced ; Hemorrhage/complications ; Neoplasms/complications ; Neoplasms/drug therapy
Chemical Substances	Dalteparin (S79O08V79F) ; apixaban (3Z9Y7UWC1J) ; Anticoagulants
Language	English
Publishing date	2023-10-20
Publishing country	Switzerland
Document type	Meta-Analysis ; Systematic Review ; Journal Article ; Review
ZDB-ID	2188113-3
ISSN	1648-9144 ; 1010-660X
ISSN (online)	1648-9144
ISSN	1010-660X
DOI	10.3390/medicina59101867
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Article ; Online: Disparities in breast cancer mortality among Latin American women: trends and predictions for 2030.

Torres-Román, J Smith / Ybaseta-Medina, Jorge / Loli-Guevara, Silvana / Bazalar-Palacios, Janina / Valcarcel, Bryan / Arce-Huamani, Miguel A / Alvarez, Christian S / Hurtado-Roca, Yamilee

BMC public health

2023 Volume 23, Issue 1, Page(s) 1449

Abstract: Background: Breast cancer is among the leading cause of cancer-related mortality among Latin American and Caribbean (LAC) women, but a comprehensive and updated analysis of mortality trends is lacking. The objective of this study was to determine the ... ...

Abstract	Background: Breast cancer is among the leading cause of cancer-related mortality among Latin American and Caribbean (LAC) women, but a comprehensive and updated analysis of mortality trends is lacking. The objective of this study was to determine the breast cancer mortality rates between 1997 and 2017 for LAC countries and predict mortality until 2030. Methods: We retrieved breast cancer deaths across 17 LAC countries from the World Health Organization mortality database. Age-standardized mortality rates per 100,000 women-years were estimated. Mortality trends were evaluated with Joinpoint regression analyses by country and age group (all ages, < 50 years, and ≥ 50 years). By 2030, we predict number of deaths, mortality rates, changes in population structure and size, and the risk of death from breast cancer. Results: Argentina, Uruguay, and Venezuela reported the highest mortality rates throughout the study period. Guatemala, El Salvador, and Nicaragua reported the largest increases (from 2.4 to 2.8% annually), whereas Argentina, Chile, and Uruguay reported downward trends (from - 1.0 to - 1.6% annually). In women < 50y, six countries presented downward trends and five countries showed increasing trends. In women ≥ 50y, three countries had decreased trends and ten showed increased trends. In 2030, increases in mortality are expected in the LAC region, mainly in Guatemala (+ 63.0%), Nicaragua (+ 47.3), El Salvador (+ 46.2%), Ecuador (+ 38.5%) and Venezuela (+ 29.9%). Conclusion: Our findings suggest considerable differences in breast cancer mortality across LAC countries by age group. To achieve the 2030 sustainable developmental goals, LAC countries should implement public health strategies to reduce mortality by breast cancer.
MeSH term(s)	Female ; Humans ; Middle Aged ; Latin America/epidemiology ; Breast Neoplasms ; Chile/epidemiology ; Argentina ; Guatemala/epidemiology ; Mortality
Language	English
Publishing date	2023-07-28
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2041338-5
ISSN	1471-2458 ; 1471-2458
ISSN (online)	1471-2458
ISSN	1471-2458
DOI	10.1186/s12889-023-16328-w
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Article ; Online: [No title information]

Torres-Román, Junior Smith / Montenegro-Idrogo, Juan J

Salud publica de Mexico

2017 Volume 59, Issue 1, Page(s) 1–2

Title translation	Inmunización contra el virus de papiloma humano en Perú. Más allá del cáncer de cérvix.
MeSH term(s)	Anus Neoplasms/prevention & control ; Anus Neoplasms/virology ; Female ; Humans ; Male ; Mouth Neoplasms/prevention & control ; Mouth Neoplasms/virology ; Papillomavirus Vaccines ; Peru ; Sexual and Gender Minorities ; Uterine Cervical Neoplasms/prevention & control ; Uterine Cervical Neoplasms/virology
Chemical Substances	Papillomavirus Vaccines
Language	Spanish
Publishing date	2017-10-22
Publishing country	Mexico
Document type	Letter
ZDB-ID	954220-6
ISSN	1606-7916 ; 0036-3634
ISSN (online)	1606-7916
ISSN	0036-3634
DOI	10.21149/7863
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Article ; Online: Use of ivermectin and factors associated with the prevention and/or treatment of COVID-19

David Guillen-Carbajal / Luz Campos-Loza / J. Smith Torres-Roman / Jose Salvador-Carrillo / Jorge Osada / Alejandra Zevallos

F1000Research, Vol

a cross-sectional online survey in the province of Chincha, Peru [version 3; peer review: 2 approved]

2024 Volume 12

Abstract: Background Peru has reported one of the highest mortality rates from COVID-19 worldwide. The Chincha province has been one of the most affected regions in Peru and the leading promoter of the use of ivermectin for the treatment of COVID-19. Therefore, ... ...

Abstract	Background Peru has reported one of the highest mortality rates from COVID-19 worldwide. The Chincha province has been one of the most affected regions in Peru and the leading promoter of the use of ivermectin for the treatment of COVID-19. Therefore, our study aimed to evaluate the frequency of use and factors associated with the use of ivermectin for COVID-19 in Chincha. Methods A cross-sectional study was conducted during the second wave of COVID-19 in Peru. For statistical analyses, frequencies and percentages were reported. Prevalence ratios (PR) with a 95% confidence interval (CI), and a p-value of 0.05 were used to determine statistical significance. SPSS version 22 (IBM Corp) program was used for the analyses. Results A total of 432 participants were included in the study. A total of 67.6% (n = 292) of the participants used ivermectin during the COVID-19 pandemic. Of these, 20.20% (n=59) of the people used ivermectin for prophylactic purposes only, while 41.79% (n=122) used it as treatment for COVID-19 only, and 38.01% (n=111) used it for both reasons. The consumption of ivermectin was associated with being 50 years or older (PR:1.27, 95% CI:1.04–1.54), having a technical education level (PR:1.16, 95% CI:1.01–1.34), having had symptoms of COVID-19 with negative/no diagnosis (PR: 1.28, 95% CI: 1.07–1.53) or positive diagnosis (PR:1.38, 95% CI:1.18–1.61), or having had contact with infected people (PR:1.45, 95% CI:1.06–1.98). Conclusions Most people in Chincha used ivermectin during the second wave of the COVID-19 pandemic. The main factors associated with the use of ivermectin for the prevention/treatment of COVID-19 were age ≥50 years, having a technical education level, having had symptoms with negative/no diagnosis or positive diagnosis, and contact with people infected with SARS-CoV-2.
Keywords	Ivermectin ; COVID-19 ; Treatment and Prevention ; Peru ; eng ; Medicine ; R ; Science ; Q
Subject code	150
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	F1000 Research Ltd
Document type	Article ; Online
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Article ; Online: Trends in gastric cancer mortality 2005-2020 in Peru and its geographical areas: A joinpoint regression analysis.

Smith Torres-Roman, J / Julca-Marín, Dante / Ticona-Tiña, Dayana / Quispe-Vicuña, Carlos / Bazalar-Palacios, Janina / De La Cruz-Ku, Gabriel / Ybaseta-Medina, Jorge

Cancer epidemiology

2023 Volume 87, Page(s) 102485

Abstract: Background: Gastric cancer (GC) is the leading cause of cancer death in Peru. However, information regarding trends in mortality rates in Peru and its geographical areas in the last few decades is lacking. Our objective was to describe GC mortality ... ...

Abstract	Background: Gastric cancer (GC) is the leading cause of cancer death in Peru. However, information regarding trends in mortality rates in Peru and its geographical areas in the last few decades is lacking. Our objective was to describe GC mortality rates in Peru between 2005 and 2020. Methods: Age standardized mortality rates (ASMR) were calculated per 100,000 person-years using the world SEGI standard population. Joinpoint regression analysis was performed to examine mortality trends. The analysis of the last 5 years was performed for Peru and its geographical areas. Results: GC mortality rates in 2005 and in 2020 were 13.81 and 10.52, respectively, for men and 11.81 and 8.06, respectively, for women. Between 2016 and 2020, Huanuco and Huancavelica reported the highest mortality rates (≥20 deaths per 100,000). In men, Peru and the highlands region reported significant decreases in GC mortality rates in both sexes for some periods. Coastal region significant decreased by 2.6 % in all periods for women. In both sexes, six provinces reported significant decreases in GC mortality rates. Conclusion: Although GC mortality rates in Peru have declined over the past 16 years. They are still one of the highest in the Latin American and Caribbean region. It is important that the Peruvian State seek to reduce the mortality of this disease through prevention efforts, timely detection and treatment in all patients.
MeSH term(s)	Male ; Humans ; Female ; Stomach Neoplasms/epidemiology ; Peru/epidemiology ; Racial Groups ; Caribbean Region ; Mortality
Language	English
Publishing date	2023-11-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2508729-0
ISSN	1877-783X ; 1877-7821
ISSN (online)	1877-783X
ISSN	1877-7821
DOI	10.1016/j.canep.2023.102485
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Article ; Online: Mortality Trends for Lung Cancer and Smoking Prevalence In Peru.

Torres-Roman, J Smith / Valcarcel, Bryan / Martinez-Herrera, Jose Fabian / Bazalar-Palacios, Janina / La Vecchia, Carlo / Raez, Luis E

Asian Pacific journal of cancer prevention : APJCP

2022 Volume 23, Issue 2, Page(s) 435–443

Abstract: Objectives: Lung cancer continues to be the leading cause of cancer-related deathworldwide. Have been reported high mortality rates from lung cancer in Latin America, but the disparities within the regions of Peru and under-reporting death ... ...

Abstract	Objectives: Lung cancer continues to be the leading cause of cancer-related deathworldwide. Have been reported high mortality rates from lung cancer in Latin America, but the disparities within the regions of Peru and under-reporting death certification reported prevent the inclusion of Peru in analysis of the mortality trends for lung cancer. We evaluated lung cancer mortality trends and smoking prevalence in Peru and its geographical areas. Materials and methods: We obtained the data from the registry of the Peruvian Ministry of Health between 2008 and 2017. Mortality rates per 100,000 person-years were computed using the world's SEGI population and trends were analyzed using the Joinpoint regression Program Version 4.7.0. Smoking prevalence was estimated from the Demographic and Family Health Survey. Results: In Peru, mortality rates were roughly 1.3 times higher in males than in females. The coast region had significant downward trends among males, whereas the highlands region had significant upward trends among females. According to provinces, Apurimac showed an annually significant rise in both sexes (+10.6% in males, and +11.6% in females). In general, smoking prevalence was higher in males compared to females, principally among young adults. Conclusions: Peru showed downward mortality trends in the last decade with variability across regions. Males had a higher smoking prevalence, principally among young adults. Public health interventions for smoking reduction should be implemented to reduce lung cancer mortality.
MeSH term(s)	Adult ; Aged ; Female ; Humans ; Lung Neoplasms/mortality ; Male ; Middle Aged ; Mortality/trends ; Peru ; Prevalence ; Registries ; Smoking/epidemiology
Language	English
Publishing date	2022-02-01
Publishing country	Thailand
Document type	Journal Article
ZDB-ID	2218955-5
ISSN	2476-762X ; 1513-7368
ISSN (online)	2476-762X
ISSN	1513-7368
DOI	10.31557/APJCP.2022.23.2.435
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