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  1. Article ; Online: Personalized lattice-structured prosthesis as a graftless solution for mandible reconstruction and prosthetic restoration: A finite element analysis.

    Longhitano, Guilherme Arthur / Chiarelli, Murillo / Prada, Daniel / Zavaglia, Cecília Amélia de Carvalho / Maciel Filho, Rubens

    Journal of the mechanical behavior of biomedical materials

    2024  Volume 152, Page(s) 106460

    Abstract: Oral cavity tumors are a prevalent cause of mandible reconstruction surgeries. The mandible is vital for functions like oralization, respiration, mastication, and deglutition. Current mandible reconstruction methods have low success rates due to ... ...

    Abstract Oral cavity tumors are a prevalent cause of mandible reconstruction surgeries. The mandible is vital for functions like oralization, respiration, mastication, and deglutition. Current mandible reconstruction methods have low success rates due to complications like plate fracture or exposure, infections, and screw loosening. Autogenous bone grafts are commonly used but carry the risk of donor region morbidity. Despite technological advances, an ideal solution for mandible reconstruction remains elusive. Additive manufacturing in medicine offers personalized prosthetics from patient-specific medical images, allowing for the creation of porous structures with tailored mechanical properties that mimic bone properties. This study compared a commercial reconstruction plate with a lattice-structured personalized prosthesis under different biting and osseointegration conditions using Finite Element Analysis. Patient-specific images were obtained from an individual who underwent mandible reconstruction with a commercial plate and suffered from plate fracture by fatigue after 26 months. Compared to the commercial plate, the maximum von Mises equivalent stress was significantly lowered for the personalized prosthesis, hindering a possible fatigue fracture. The equivalent von Mises strains found in bone were within bone maintenance and remodeling intervals. This work introduces a design that doesn't require grafts for large bone defects and allows for dental prosthesis addition without the need for implants.
    MeSH term(s) Humans ; Finite Element Analysis ; Bone Plates ; Bone Screws ; Bone Transplantation ; Mandible/surgery
    Language English
    Publishing date 2024-02-06
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2378381-3
    ISSN 1878-0180 ; 1751-6161
    ISSN (online) 1878-0180
    ISSN 1751-6161
    DOI 10.1016/j.jmbbm.2024.106460
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The role of 3D printing during COVID-19 pandemic: a review.

    Longhitano, Guilherme Arthur / Nunes, Guilherme Bitencourt / Candido, Geovany / da Silva, Jorge Vicente Lopes

    Progress in additive manufacturing

    2020  Volume 6, Issue 1, Page(s) 19–37

    Abstract: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread through more than 180 countries, leading to diverse health systems overload around the world. Because of the high number ... ...

    Abstract The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has spread through more than 180 countries, leading to diverse health systems overload around the world. Because of the high number of patients and the supply chain disruption, it generated a shortage of medical devices and personal protective equipment. In this context, initiatives from the additive manufacturing community emerged to fight the lack of devices. Diverse designs were produced and are currently being used in hospitals by patients and health workers. However, as some devices must follow strict standards, these products may not fulfill these standards. Therefore, to ensure the user's health, there is a need for understanding each device, their usage, and standards. This study reviews the use of additive manufacturing during COVID-19 pandemic. It gathers the source of several 3D printed devices such as face shields, face masks, valves, nasopharyngeal swabs, and others, discussing their use and regulatory issues. In this regard, the major drawbacks of the technology, addressed for the next pandemic scenario, are highlighted. Finally, some insights of the future of additive manufacturing during emergency are given and discussed.
    Language English
    Publishing date 2020-11-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2842521-2
    ISSN 2363-9520 ; 2363-9512
    ISSN (online) 2363-9520
    ISSN 2363-9512
    DOI 10.1007/s40964-020-00159-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Osseointegration Improvement of Co-Cr-Mo Alloy Produced by Additive Manufacturing.

    Iatecola, Amilton / Longhitano, Guilherme Arthur / Antunes, Luiz Henrique Martinez / Jardini, André Luiz / Miguel, Emilio de Castro / Béreš, Miloslav / Lambert, Carlos Salles / Andrade, Tiago Neves / Buchaim, Rogério Leone / Buchaim, Daniela Vieira / Pomini, Karina Torres / Dias, Jefferson Aparecido / Spressão, Daniele Raineri Mesquita Serva / Felix, Marcílio / Cardoso, Guinea Brasil Camargo / da Cunha, Marcelo Rodrigues

    Pharmaceutics

    2021  Volume 13, Issue 5

    Abstract: Cobalt-base alloys (Co-Cr-Mo) are widely employed in dentistry and orthopedic implants due to their biocompatibility, high mechanical strength and wear resistance. The osseointegration of implants can be improved by surface modification techniques. ... ...

    Abstract Cobalt-base alloys (Co-Cr-Mo) are widely employed in dentistry and orthopedic implants due to their biocompatibility, high mechanical strength and wear resistance. The osseointegration of implants can be improved by surface modification techniques. However, complex geometries obtained by additive manufacturing (AM) limits the efficiency of mechanical-based surface modification techniques. Therefore, plasma immersion ion implantation (PIII) is the best alternative, creating nanotopography even in complex structures. In the present study, we report the osseointegration results in three conditions of the additively manufactured Co-Cr-Mo alloy: (i) as-built, (ii) after PIII, and (iii) coated with titanium (Ti) followed by PIII. The metallic samples were designed with a solid half and a porous half to observe the bone ingrowth in different surfaces. Our results revealed that all conditions presented cortical bone formation. The titanium-coated sample exhibited the best biomechanical results, which was attributed to the higher bone ingrowth percentage with almost all medullary canals filled with neoformed bone and the pores of the implant filled and surrounded by bone ingrowth. It was concluded that the metal alloys produced for AM are biocompatible and stimulate bone neoformation, especially when the Co-28Cr-6Mo alloy with a Ti-coated surface, nanostructured and anodized by PIII is used, whose technology has been shown to increase the osseointegration capacity of this implant.
    Language English
    Publishing date 2021-05-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics13050724
    Database MEDical Literature Analysis and Retrieval System OnLINE

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