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Article ; Online: Protocol for prophylaxis of venous thromboembolism in varicose vein surgery of the lower limbs.

Marques, Marcos Arêas / Fiorelli, Stênio Karlos Alvim / Barros, Bernardo Cunha Senra / Ribeiro, Alcides José Araújo / Ristow, Arno VON / Fiorelli, Rossano Kepler Alvim

Revista do Colegio Brasileiro de Cirurgioes

2022 Volume 49, Page(s) e20223326

Abstract: Pulmonary embolism is the most feared complication of venous thromboembolism (VTE) and the third leading cause of cardiovascular mortality in the world, after acute myocardial infarction and stroke. The risk of VTE is virtually universal in hospitalized ... ...

Abstract	Pulmonary embolism is the most feared complication of venous thromboembolism (VTE) and the third leading cause of cardiovascular mortality in the world, after acute myocardial infarction and stroke. The risk of VTE is virtually universal in hospitalized patients, especially those with reduced mobility. Although variable in incidence between clinical and surgical patients, up to 66.6% of events related to hospitalizations can occur after discharge, with this risk remaining for up to 90 days. Despite all the investment made in VTE prophylaxis in recent decades, there is still no consensus or specific guidelines for its prevention in patients undergoing conventional surgery for varicose veins of lower limbs. The adoption of a validated risk assessment model for VTE prophylaxis, based on the current literature, may help in the implementation and standardization of VTE prophylaxis in conventional lower limb varicose vein surgery, in addition to this benefit, it may lead to a reduction in the length of hospital stay and the number of readmissions.
MeSH term(s)	Anticoagulants/therapeutic use ; Humans ; Lower Extremity/surgery ; Pulmonary Embolism ; Risk Factors ; Varicose Veins/surgery ; Venous Thromboembolism/etiology ; Venous Thromboembolism/prevention & control
Chemical Substances	Anticoagulants
Language	Portuguese
Publishing date	2022-08-22
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2223714-8
ISSN	1809-4546 ; 1809-4546
ISSN (online)	1809-4546
ISSN	1809-4546
DOI	10.1590/0100-6991e-20223326-en
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The role of Angiology and Vascular Surgery in the COVID-19 pandemic.

Barros, Bernardo Cunha Senra / Maia, Aline Barbosa / Marques, Marcos Arêas / Prette-Junior, Paulo Roberto / Fiorelli, Stenio Karlos Alvim / Cerqueira, Fernanda DE Castro

Revista do Colegio Brasileiro de Cirurgioes

2020 Volume 47, Page(s) e20202595

Abstract: The New Coronavirus Epidemic (2019-nCoV), discovered in the city of Wuhan, China, in December 2019, presents mainly with pulmonary pneumonia that is preceded by fever, cough and myalgia. However, as the disease spread globally and the number of ... ...

Abstract	The New Coronavirus Epidemic (2019-nCoV), discovered in the city of Wuhan, China, in December 2019, presents mainly with pulmonary pneumonia that is preceded by fever, cough and myalgia. However, as the disease spread globally and the number of hospitalizations increased exponentially, it was noted that most serious patients hospitalized by COVID-19 have laboratory changes worthy of attention, such as lymphopenia, neutrophilia, increased time of prothrombin and increased levels of D-dimer. Due to these changes proving to be crucial for the mortality and morbidity rates in this subset of infected people, several studies focusing on the pathophysiology, mainly hematological, of the disease appear every day. Deepening these studies, several published works have shown SarsCoV-2 infection to the installation of a prothrombotic state in hospitalized patients, which leads to the potential occurrence of thrombotic or arterial events in this cohort. Thus, in order to understand how the departments of Angiology and Vascular Surgery are acting in the context of the COVID-19 pandemic, this work aims to gather studies that reveal from protocols applied in vascular services in the current situation, until to the role of vascular surgeons and angiologists in the clinical and surgical management of patients infected or not, as a way of helping and clarifying this specialty during the context of a pandemic due to the new coranavirus. For the selection of works, the following search criteria were used: "Coronavirus and venous thrombosis", "Coronavirus and thrombosis", "COVID-19 and venous thrombosis" and "COVID-19 Coronavirus and thrombosis".
MeSH term(s)	Betacoronavirus ; Blood Coagulation/physiology ; COVID-19 ; Clinical Protocols ; Coronavirus Infections/complications ; Coronavirus Infections/physiopathology ; Humans ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/physiopathology ; Pulmonary Embolism/diagnosis ; Pulmonary Embolism/therapy ; Pulmonary Embolism/virology ; SARS-CoV-2 ; Thromboembolism/diagnosis ; Thromboembolism/therapy ; Thromboembolism/virology ; Vascular Surgical Procedures/methods ; Vascular Surgical Procedures/standards
Keywords	covid19
Language	Portuguese
Publishing date	2020-06-01
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2223714-8
ISSN	1809-4546 ; 0100-6991
ISSN (online)	1809-4546
ISSN	0100-6991
DOI	10.1590/0100-6991e-20202595
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Article ; Online: The role of Angiology and Vascular Surgery in the COVID-19 pandemic

BARROS, BERNARDO CUNHA SENRA / MAIA, ALINE BARBOSA / MARQUES, MARCOS ARÊAS / PRETTE-JUNIOR, PAULO ROBERTO / FIORELLI, STENIO KARLOS ALVIM / CERQUEIRA, FERNANDA DE CASTRO

Revista do Colégio Brasileiro de Cirurgiões v.47 2020

2020

Abstract: ABSTRACT The New Coronavirus Epidemic (2019-nCoV), discovered in the city of Wuhan, China, in December 2019, presents mainly with pulmonary pneumonia that is preceded by fever, cough and myalgia. However, as the disease spread globally and the number of ... ...

Abstract	ABSTRACT The New Coronavirus Epidemic (2019-nCoV), discovered in the city of Wuhan, China, in December 2019, presents mainly with pulmonary pneumonia that is preceded by fever, cough and myalgia. However, as the disease spread globally and the number of hospitalizations increased exponentially, it was noted that most serious patients hospitalized by COVID-19 have laboratory changes worthy of attention, such as lymphopenia, neutrophilia, increased time of prothrombin and increased levels of D-dimer. Due to these changes proving to be crucial for the mortality and morbidity rates in this subset of infected people, several studies focusing on the pathophysiology, mainly hematological, of the disease appear every day. Deepening these studies, several published works have shown SarsCoV-2 infection to the installation of a prothrombotic state in hospitalized patients, which leads to the potential occurrence of thrombotic or arterial events in this cohort. Thus, in order to understand how the departments of Angiology and Vascular Surgery are acting in the context of the COVID-19 pandemic, this work aims to gather studies that reveal from protocols applied in vascular services in the current situation, until to the role of vascular surgeons and angiologists in the clinical and surgical management of patients infected or not, as a way of helping and clarifying this specialty during the context of a pandemic due to the new coranavirus. For the selection of works, the following search criteria were used: “Coronavirus and venous thrombosis”, “Coronavirus and thrombosis”, “COVID-19 and venous thrombosis” and “COVID-19 Coronavirus and thrombosis”.
Keywords	Coronavirus Infections ; Blood Coagulation ; Thrombosis ; Pulmonary Embolism ; Coronavirus ; covid19
Subject code	610
Language	English
Publishing date	2020-01-01
Publisher	Colégio Brasileiro de Cirurgiões
Publishing country	br
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Efficacy of varicose vein surgery with preservation of the great safenous vein.

Barros, Bernardo Cunha Senra / Araujo, Antonio Luiz de / Magalhães, Carlos Eduardo Virgini / Barros, Raimundo Luiz Senra / Fiorelli, Stenio Karlos Alvim / Gatts, Raphaella Ferreira

Revista do Colegio Brasileiro de Cirurgioes

2015 Volume 42, Issue 2, Page(s) 111–115

Abstract: Objective: To evaluate the efficacy of surgical treatment of varicose veins with preservation of the great saphenous vein.: Methods: We conducted a prospective study of 15 female patients between 25 and 55 years of age with clinical, etiologic, ... ...

Abstract	Objective: To evaluate the efficacy of surgical treatment of varicose veins with preservation of the great saphenous vein. Methods: We conducted a prospective study of 15 female patients between 25 and 55 years of age with clinical, etiologic, anatomic and pathophysiologic (CEAP) classification 2, 3 and 4. The patients underwent surgical treatment of primary varicose veins with great saphenous vein (GSV) preservation. Doppler ultrasonography exams were carried out in the first and third months postoperatively. The form of clinical severity of venous disease, Venous Clinical Severity Score (VCSS) was completed before and after surgery. We excluded patients with history of deep vein thrombosis, smoking or postoperatively use of elastic stockings or phlebotonics. Results: All patients had improved VCSS (p <0.001) and reduction in the diameter of the great saphenous vein (p <0.001). There was a relationship between VCSS and the GSV caliber, as well as with preoperative CEAP. There was improvement in CEAP class in nine patients when compared with the preoperative period (p <0.001). Conclusion: The varicose vein surgery with preservation of the great saphenous vein had beneficial effects to the GSV itself, with decreasing caliber, and to the symptoms when the vein had maximum caliber of 7.5 mm, correlating directly with the CEAP. The decrease in GSV caliber, even without complete abolition of reflux, leads to clinical improvement by decreasing the reflux volume.
MeSH term(s)	Adult ; Female ; Humans ; Middle Aged ; Organ Sparing Treatments ; Prospective Studies ; Saphenous Vein ; Treatment Outcome ; Varicose Veins/surgery ; Vascular Surgical Procedures/methods
Language	Portuguese
Publishing date	2015-03
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2223714-8
ISSN	1809-4546 ; 0100-6991
ISSN (online)	1809-4546
ISSN	0100-6991
DOI	10.1590/0100-69912015002008
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Article: The role of Angiology and Vascular Surgery in the COVID-19 pandemic

Barros, Bernardo Cunha Senra / Maia, Aline Barbosa / Marques, Marcos Arêas / Prette-Junior, Paulo Roberto / Fiorelli, Stenio Karlos Alvim / Cerqueira, Fernanda DE Castro

Rev Col Bras Cir

Abstract	The New Coronavirus Epidemic (2019-nCoV), discovered in the city of Wuhan, China, in December 2019, presents mainly with pulmonary pneumonia that is preceded by fever, cough and myalgia. However, as the disease spread globally and the number of hospitalizations increased exponentially, it was noted that most serious patients hospitalized by COVID-19 have laboratory changes worthy of attention, such as lymphopenia, neutrophilia, increased time of prothrombin and increased levels of D-dimer. Due to these changes proving to be crucial for the mortality and morbidity rates in this subset of infected people, several studies focusing on the pathophysiology, mainly hematological, of the disease appear every day. Deepening these studies, several published works have shown SarsCoV-2 infection to the installation of a prothrombotic state in hospitalized patients, which leads to the potential occurrence of thrombotic or arterial events in this cohort. Thus, in order to understand how the departments of Angiology and Vascular Surgery are acting in the context of the COVID-19 pandemic, this work aims to gather studies that reveal from protocols applied in vascular services in the current situation, until to the role of vascular surgeons and angiologists in the clinical and surgical management of patients infected or not, as a way of helping and clarifying this specialty during the context of a pandemic due to the new coranavirus. For the selection of works, the following search criteria were used: "Coronavirus and venous thrombosis", "Coronavirus and thrombosis", "COVID-19 and venous thrombosis" and "COVID-19 Coronavirus and thrombosis".
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32490891
Database	COVID19

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Article ; Online: Efficacy of varicose vein surgery with preservation of the great safenous vein

Bernardo Cunha Senra Barros / Antonio Luiz de Araujo / Carlos Eduardo Virgini Magalhães / Raimundo Luiz Senra Barros / Stenio Karlos Alvim Fiorelli / Raphaella Ferreira Gatts

Revista do Colégio Brasileiro de Cirurgiões, Vol 42, Iss 2, Pp 111-

2015 Volume 115

Abstract: OBJECTIVE: To evaluate the efficacy of surgical treatment of varicose veins with preservation of the great saphenous vein. METHODS: We conducted a prospective study of 15 female patients between 25 and 55 years of age with clinical, etiologic, anatomic ... ...

Abstract	OBJECTIVE: To evaluate the efficacy of surgical treatment of varicose veins with preservation of the great saphenous vein. METHODS: We conducted a prospective study of 15 female patients between 25 and 55 years of age with clinical, etiologic, anatomic and pathophysiologic (CEAP) classification 2, 3 and 4. The patients underwent surgical treatment of primary varicose veins with great saphenous vein (GSV) preservation. Doppler ultrasonography exams were carried out in the first and third months postoperatively. The form of clinical severity of venous disease, Venous Clinical Severity Score (VCSS) was completed before and after surgery. We excluded patients with history of deep vein thrombosis, smoking or postoperatively use of elastic stockings or phlebotonics. RESULTS: All patients had improved VCSS (p <0.001) and reduction in the diameter of the great saphenous vein (p <0.001). There was a relationship between VCSS and the GSV caliber, as well as with preoperative CEAP. There was improvement in CEAP class in nine patients when compared with the preoperative period (p <0.001). CONCLUSION: The varicose vein surgery with preservation of the great saphenous vein had beneficial effects to the GSV itself, with decreasing caliber, and to the symptoms when the vein had maximum caliber of 7.5 mm, correlating directly with the CEAP. The decrease in GSV caliber, even without complete abolition of reflux, leads to clinical improvement by decreasing the reflux volume.
Keywords	Insuficiência venosa ; Varizes ; Veia safena ; Veia safena/ultrassografia ; Veia safena/cirurgia ; Surgery ; RD1-811 ; Medicine ; R
Subject code	610
Language	Portuguese
Publishing date	2015-04-01T00:00:00Z
Publisher	Colégio Brasileiro de Cirurgiões
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The effects of supraphysiological supplementation of β-carotene in spontaneously hypertensive rats (SHR and SHR-sp).

Fiorelli, Stênio Karlos Alvim / Vianna, Lúcia Marques / Oliveira, Carlos Alberto Basílio de / Fiorelli, Rossano Kepler Alvim / Barros, Bernardo Cunha Senra / Almeida, Camila Rodrigues de

Revista do Colegio Brasileiro de Cirurgioes

2014 Volume 41, Issue 5, Page(s) 351–355

Abstract: Objective: To investigate the effect of administration of supraphysiological β carotene on biological, laboratory and histological parameters of spontaneously hypertensive rats prone to stroke (SHR-sp).: Methods: we used 36 male rats divided into ... ...

Abstract	Objective: To investigate the effect of administration of supraphysiological β carotene on biological, laboratory and histological parameters of spontaneously hypertensive rats prone to stroke (SHR-sp). Methods: we used 36 male rats divided into three groups, each containing 12 rats of the types Wistar SHR and SHR-sp, subdivided into six control animals and six animals treated with supraphysiological doses of β carotene for two ten-week periods, interspersed by a one-week interruption. We carried out daily physical examination and blood pressure assessment. We collected blood for measurement of serum malondialdehyde; the liver and carotid arteries were subsequently harvested for histological examination. Results: there was a temporary change in the color of hair, a significant decrease (p <0.0001) in blood pressure (20 mg β carotene supplementation) and serum levels of malondialdehyde (p<0.05) and increased amount of elastic fibers in the carotid wall of SHR and SHR-sp. Conclusion: β carotene supraphysiological supplementation caused no toxic effects, showed positive response in the modulation of blood pressure and lower serum malondialdehyde. No significant morphological changes were observed in the groups studied, except for an increase in the number of elastic fibers in the carotid muscular layer, suggesting elastosis in SHR and SHR-sp.
MeSH term(s)	Animals ; Blood Pressure/drug effects ; Dietary Supplements ; Hypertension/drug therapy ; Male ; Rats ; Rats, Inbred SHR ; Rats, Wistar ; beta Carotene/pharmacology ; beta Carotene/therapeutic use
Chemical Substances	beta Carotene (01YAE03M7J)
Language	Portuguese
Publishing date	2014-11-21
Publishing country	Brazil
Document type	Journal Article
ZDB-ID	2223714-8
ISSN	1809-4546 ; 0100-6991
ISSN (online)	1809-4546
ISSN	0100-6991
DOI	10.1590/0100-69912014005010
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Article ; Online: The effects of supraphysiological supplementation of b-carotene in spontaneously hypertensive rats (SHR and SHR-sp)

Stênio Karlos Alvim Fiorelli / Lúcia Marques Vianna / Carlos Alberto Basílio de Oliveira / Rossano Kepler Alvim Fiorelli / Bernardo Cunha Senra Barros / Camila Rodrigues de Almeida

Revista do Colégio Brasileiro de Cirurgiões, Vol 41, Iss 5, Pp 351-

2014 Volume 355

Abstract: Objective: to investigate the effect of administration of supraphysiological âcaroteno on biological parameters (ectoscopy and blood pressure), laboratory (malondialdehyde) and histological (liver and carotid arteries) of spontaneously hypertensive rats ... ...

Abstract	Objective: to investigate the effect of administration of supraphysiological âcaroteno on biological parameters (ectoscopy and blood pressure), laboratory (malondialdehyde) and histological (liver and carotid arteries) of spontaneously hypertensive rats prone to stroke (SHR-sp). Methods: we used 36 male rats were divided into three groups, each containing 12 rats Wistar, SHR and SHR-sp, subdivided into six control animals and six animals treated with supraphysiological doses of âcaroteno for two periods of ten weeks interspersed with one week interruption. In the experiment were assessed daily physical examination and blood pressure (plethysmography). At sacrifice, blood was collected for measurement of serum malondialdehyde, liver and carotid arteries for histological examination. Results: temporary change in color of the fur, decreased significantly (p<0.0001) blood pressure (20mg supplementation âcaroteno) and serum levels of malondialdehyde (p<0.05) and increased amount of elastic fibers in the carotid wall of SHR and SHR-sp. Conclusion: supplementation of supraphysiological âcaroteno caused no toxic effects, showed positive response in the modulation of blood pressure and lower serum malondialdehyde. No significant morphological changes were found in both groups, except an increase in the number of elastic fibers in the muscle layer carotid suggesting elastosis in SHR and SHR-sp.
Keywords	Estresse oxidativo ; Malondialdeído ; Betacaroteno ; Ratos ; Surgery ; RD1-811 ; Medicine ; R
Subject code	630
Language	Portuguese
Publishing date	2014-10-01T00:00:00Z
Publisher	Colégio Brasileiro de Cirurgiões
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The effects of supraphysiological supplementation of b-carotene in spontaneously hypertensive rats (SHR and SHR-sp)

Stênio Karlos Alvim Fiorelli / Lúcia Marques Vianna / Carlos Alberto Basílio de Oliveira / Rossano Kepler Alvim Fiorelli / Bernardo Cunha Senra Barros / Camila Rodrigues de Almeida

Revista do Colégio Brasileiro de Cirurgiões, Vol 41, Iss 5, Pp 351-

2014 Volume 355

Abstract	Objective: to investigate the effect of administration of supraphysiological âcaroteno on biological parameters (ectoscopy and blood pressure), laboratory (malondialdehyde) and histological (liver and carotid arteries) of spontaneously hypertensive rats prone to stroke (SHR-sp). Methods: we used 36 male rats were divided into three groups, each containing 12 rats Wistar, SHR and SHR-sp, subdivided into six control animals and six animals treated with supraphysiological doses of âcaroteno for two periods of ten weeks interspersed with one week interruption. In the experiment were assessed daily physical examination and blood pressure (plethysmography). At sacrifice, blood was collected for measurement of serum malondialdehyde, liver and carotid arteries for histological examination. Results: temporary change in color of the fur, decreased significantly (p<0.0001) blood pressure (20mg supplementation âcaroteno) and serum levels of malondialdehyde (p<0.05) and increased amount of elastic fibers in the carotid wall of SHR and SHR-sp. Conclusion: supplementation of supraphysiological âcaroteno caused no toxic effects, showed positive response in the modulation of blood pressure and lower serum malondialdehyde. No significant morphological changes were found in both groups, except an increase in the number of elastic fibers in the muscle layer carotid suggesting elastosis in SHR and SHR-sp.
Keywords	Estresse oxidativo ; Malondialdeído ; Betacaroteno ; Ratos ; Surgery ; RD1-811 ; Medicine ; R
Subject code	630
Language	Portuguese
Publishing date	2014-10-01T00:00:00Z
Publisher	Colégio Brasileiro de Cirurgiões
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The effects of supraphysiological supplementation of b-carotene in spontaneously hypertensive rats (SHR and SHR-sp)

Stênio Karlos Alvim Fiorelli / Lúcia Marques Vianna / Carlos Alberto Basílio de Oliveira / Rossano Kepler Alvim Fiorelli / Bernardo Cunha Senra Barros / Camila Rodrigues de Almeida

Revista do Colégio Brasileiro de Cirurgiões, Vol 41, Iss 5, Pp 351-

2014 Volume 355

Abstract	Objective: to investigate the effect of administration of supraphysiological âcaroteno on biological parameters (ectoscopy and blood pressure), laboratory (malondialdehyde) and histological (liver and carotid arteries) of spontaneously hypertensive rats prone to stroke (SHR-sp). Methods: we used 36 male rats were divided into three groups, each containing 12 rats Wistar, SHR and SHR-sp, subdivided into six control animals and six animals treated with supraphysiological doses of âcaroteno for two periods of ten weeks interspersed with one week interruption. In the experiment were assessed daily physical examination and blood pressure (plethysmography). At sacrifice, blood was collected for measurement of serum malondialdehyde, liver and carotid arteries for histological examination. Results: temporary change in color of the fur, decreased significantly (p<0.0001) blood pressure (20mg supplementation âcaroteno) and serum levels of malondialdehyde (p<0.05) and increased amount of elastic fibers in the carotid wall of SHR and SHR-sp. Conclusion: supplementation of supraphysiological âcaroteno caused no toxic effects, showed positive response in the modulation of blood pressure and lower serum malondialdehyde. No significant morphological changes were found in both groups, except an increase in the number of elastic fibers in the muscle layer carotid suggesting elastosis in SHR and SHR-sp.
Keywords	Estresse oxidativo ; Malondialdeído ; Betacaroteno ; Ratos ; Surgery ; RD1-811 ; Medicine ; R
Subject code	630
Language	Portuguese
Publishing date	2014-10-01T00:00:00Z
Publisher	Colégio Brasileiro de Cirurgiões
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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