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  1. Book ; Online ; Conference proceedings: Selected Papers from the 11th Asian Rock Mechanics Symposium (ARMS 11)

    Zhu, Chun / Tao, Zhigang / Yang, Xiaojie / Sun, Jianping / Yang, Xiaojie

    2022  

    Keywords Technology: general issues ; History of engineering & technology ; kaolin ; cemented coal gangue-fly ash backfill sample ; mechanical properties ; macroscopic failure ; microstructure ; non-pillar coal mining ; crushed rocks ; compression test ; deformation characteristics ; lateral stress ; tunnel through fault ; concrete lining structure ; fault dislocation ; seismic deterioration effect ; dynamic contact force ; seismic damage analysis ; directions of incident waves ; slope topography ; amplification effects ; ground motions ; equivalent nodal forces ; tight sandstone gas reservoirs ; rock-physics template ; Biot-Rayleigh theory ; total porosity ; microcrack porosity ; n/a
    Language 0|e
    Size 1 electronic resource (110 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online ; Conference proceedings
    Note English ; Open Access
    HBZ-ID HT021611309
    ISBN 9783036532691 ; 3036532692
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Analysis of growth dynamics in five different media and metabolic phenotypic characteristics of

    Hu, Jing-Rong / Li, Jin-Meng / Wang, Hai-Yan / Sun, Mei-Li / Huang, Chun-Yang / Wang, Han-Cheng

    Frontiers in microbiology

    2024  Volume 14, Page(s) 1301743

    Abstract: Piriformospora ... ...

    Abstract Piriformospora indica
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1301743
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Exogenous Co-Reactant-Free Electrochemiluminescent Biosensor for Ratiometric Measurement of α-Glucosidase Based on a ZIF-67-Regulated Hydrogen-Bonded Organic Framework.

    Cui, Lin / Yang, Yuncong / Jiang, Su / Cao, Xueting / Chu, Wenqi / Chen, Jianwei / Sun, Bing / Ren, Kewei / Zhang, Chun-Yang

    ACS sensors

    2024  Volume 9, Issue 2, Page(s) 1023–1030

    Abstract: The development of highly sensitive and selective analytical approaches for monitoring enzymatic activity is critical for disease diagnosis and biomedical research. Herein, we develop an exogenous co-reactant-free electrochemiluminescence (ECL) biosensor ...

    Abstract The development of highly sensitive and selective analytical approaches for monitoring enzymatic activity is critical for disease diagnosis and biomedical research. Herein, we develop an exogenous co-reactant-free electrochemiluminescence (ECL) biosensor for the ratiometric measurement of α-glucosidase (α-Glu) based on a zeolitic imidazolate framework (ZIF-67)-regulated pyrene-based hydrogen-bonded organic framework (HOF-101). Target α-Glu can hydrolyze maltose to α-d-glucose, which can subsequently react with GO
    MeSH term(s) Humans ; alpha-Glucosidases ; Luminescent Measurements/methods ; Reproducibility of Results ; Luminol ; Biosensing Techniques/methods ; Gluconates
    Chemical Substances gluconic acid (R4R8J0Q44B) ; alpha-Glucosidases (EC 3.2.1.20) ; Luminol (5EXP385Q4F) ; Gluconates
    Language English
    Publishing date 2024-02-14
    Publishing country United States
    Document type Journal Article
    ISSN 2379-3694
    ISSN (online) 2379-3694
    DOI 10.1021/acssensors.4c00036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Tumor pH-triggered "charge conversion" nanocarriers with on-demand drug release for precise cancer therapy.

    Ma, Bo-Ai / Sun, Chun-Yang

    Journal of materials chemistry. B

    2020  Volume 8, Issue 40, Page(s) 9351–9361

    Abstract: Combined X-ray-induced photodynamic therapy (X-PDT) and chemotherapy are of great interest for tumor treatment, but their outcome is still hindered by insufficient drug delivery without tumor specificity and the difficulty of switching to chemotherapy ... ...

    Abstract Combined X-ray-induced photodynamic therapy (X-PDT) and chemotherapy are of great interest for tumor treatment, but their outcome is still hindered by insufficient drug delivery without tumor specificity and the difficulty of switching to chemotherapy during the X-PDT process. Herein, we report an efficient strategy for preparing a nanocarrier, DANPVP&DOX, with slight-acidity-induced charge conversion and hypoxia-motivated doxorubicin (DOX) release properties to achieve a more precise and synchronous therapeutic effect. Upon a change in the extracellular pH (pHe) in the tumor matrix, the surface charge of DANPVP&DOX converted from negative to positive via dimethyl maleate degradation. Following the increased internalization by tumoral cells, exposure of verteporfin (VP) in DANPVP&DOX to low-dose X-ray radiation resulted in O2 consumption in the cytoplasm to produce cytotoxic reactive oxygen species (ROS), which caused cell killing. Moreover, the hypoxic conditions formed in the tumor area specifically promoted DANPVP&DOX dissociation and on-demand DOX release. Consequently, DANPVP&DOX significantly increased the therapeutic efficacy through X-PDT and cascade chemotherapy. More importantly, this strategy could potentially be extended to various therapeutic agents other than anticancer drugs for precise drug delivery and cancer treatment.
    MeSH term(s) Animals ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/therapeutic use ; Cell Line, Tumor ; Doxorubicin/chemistry ; Doxorubicin/pharmacokinetics ; Doxorubicin/therapeutic use ; Drug Carriers/chemical synthesis ; Drug Carriers/chemistry ; Drug Carriers/pharmacokinetics ; Drug Liberation ; Female ; Humans ; Hydrogen-Ion Concentration ; Mice, Inbred BALB C ; Nanoparticles/chemistry ; Neoplasms/drug therapy ; Organophosphates/chemical synthesis ; Organophosphates/chemistry ; Organophosphates/pharmacokinetics ; Photochemotherapy ; Photosensitizing Agents/chemistry ; Photosensitizing Agents/pharmacokinetics ; Photosensitizing Agents/radiation effects ; Photosensitizing Agents/therapeutic use ; Polyethylene Glycols/chemical synthesis ; Polyethylene Glycols/chemistry ; Polyethylene Glycols/pharmacokinetics ; Singlet Oxygen/metabolism ; Verteporfin/chemistry ; Verteporfin/pharmacokinetics ; Verteporfin/radiation effects ; Verteporfin/therapeutic use ; X-Rays ; Xenograft Model Antitumor Assays
    Chemical Substances Antineoplastic Agents ; Drug Carriers ; Organophosphates ; Photosensitizing Agents ; Verteporfin (0X9PA28K43) ; Singlet Oxygen (17778-80-2) ; Polyethylene Glycols (3WJQ0SDW1A) ; Doxorubicin (80168379AG)
    Language English
    Publishing date 2020-09-30
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2702241-9
    ISSN 2050-7518 ; 2050-750X
    ISSN (online) 2050-7518
    ISSN 2050-750X
    DOI 10.1039/d0tb01692f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Multidisciplinary treatment of synchronous primary advanced gastric adenocarcinoma and esophageal squamous cell carcinoma-a retrospective single-institution study.

    Luo, Chun-Yang / Sun, Zheng / Jiang, Chao / Zhang, Pei-Chan / Wu, Zhen-Feng / Yao, Xue-Quan / Cao, Qin-Hong

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

    2024  Volume 28, Issue 5, Page(s) 751–753

    MeSH term(s) Humans ; Esophageal Neoplasms/pathology ; Esophageal Neoplasms/therapy ; Esophageal Neoplasms/surgery ; Retrospective Studies ; Stomach Neoplasms/pathology ; Stomach Neoplasms/therapy ; Stomach Neoplasms/surgery ; Adenocarcinoma/pathology ; Adenocarcinoma/therapy ; Adenocarcinoma/surgery ; Neoplasms, Multiple Primary/pathology ; Neoplasms, Multiple Primary/therapy ; Neoplasms, Multiple Primary/surgery ; Male ; Middle Aged ; Female ; Aged ; Carcinoma, Squamous Cell/therapy ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/surgery ; Esophageal Squamous Cell Carcinoma/therapy ; Esophageal Squamous Cell Carcinoma/pathology ; Esophageal Squamous Cell Carcinoma/surgery ; Gastrectomy/methods ; Combined Modality Therapy
    Language English
    Publishing date 2024-02-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2012365-6
    ISSN 1873-4626 ; 1934-3213 ; 1091-255X
    ISSN (online) 1873-4626 ; 1934-3213
    ISSN 1091-255X
    DOI 10.1016/j.gassur.2024.01.035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Effect of Continuous Positive Airway Pressure on Blood Pressure in Patients with Resistant Hypertension and Obstructive Sleep Apnea: An Updated Meta-analysis.

    Sun, Ling / Chang, Ya-Fei / Wang, Yun-Fei / Xie, Quan-Xin / Ran, Xian-Zhong / Hu, Chun-Yang / Luo, Bin / Ning, Bin

    Current hypertension reports

    2024  

    Abstract: Purpose of review: The effect of continuous positive airway pressure (CPAP) on resistant hypertension in patients at high risk with obstructive sleep apnea (OSA) needs further investigation. We aimed to determine the effect of CPAP on blood pressure in ... ...

    Abstract Purpose of review: The effect of continuous positive airway pressure (CPAP) on resistant hypertension in patients at high risk with obstructive sleep apnea (OSA) needs further investigation. We aimed to determine the effect of CPAP on blood pressure in patients with resistant hypertension and OSA. Databases including PubMed, EMBASE, MEDLINE, the Cochrane Library, and CMB were searched. Data were pooled using a random-effects or fixed-effects model to derive weighted mean differences (WMDs) and 95% confidence intervals (CIs).
    Recent findings: A total of 12 trials and 718 participants were included. Compared with control, CPAP significantly reduced 24-h systolic blood pressure (SBP) (WMD: - 5.92 mmHg [ - 8.72, - 3.11]; P<0.001), 24-h diastolic blood pressure (DBP) (WMD: - 4.44 mmHg [- 6.26 , - 2.62]; P  <0.001),   daytime SBP (WMD: - 5.76 mmHg [ - 9.16,  - 2.36]; P <0.001),  daytime DBP (WMD: - 3.92 mmHg [- 5.55,  - 2.30];  nighttime SBP (WMD: - 4.87 mmHg [ - 7.96 ,  - 1.78]; P = 0.002), and nighttime DBP (WMD: - 2.05 mmHg [- 2.99,  - 1.11]; P<0.001) in patients with resistant hypertension and OSA. CPAP improved the blood pressure both in the short (<3 months) and long term (≥ 3  months). No significant impact on mean heart rate was noted (WMD: -2.76 beats per min [- 7.50, 1.97]; P = 0.25). CPAP treatment was associated with BP reduction in patients with resistant hypertension and OSA.
    Language English
    Publishing date 2024-03-09
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057367-4
    ISSN 1534-3111 ; 1522-6417
    ISSN (online) 1534-3111
    ISSN 1522-6417
    DOI 10.1007/s11906-024-01294-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: [Co(2,2'-bipy)

    Tang, Chunying / Sun, Yawei / Liu, Jianbiao / Xu, Qinfeng / Zhang, Chun-Yang

    Dalton transactions (Cambridge, England : 2003)

    2022  Volume 51, Issue 44, Page(s) 16784–16789

    Abstract: We synthesized a new iodoargentate [Co(2,2'-bipy) ...

    Abstract We synthesized a new iodoargentate [Co(2,2'-bipy)
    Language English
    Publishing date 2022-11-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d2dt03128k
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Combined effects of temperature, photoperiod, and salinity on reproduction of the brine shrimp

    Yang, Jing-Yu / Sun, Shi-Chun

    PeerJ

    2023  Volume 11, Page(s) e15945

    Abstract: Background: Artemia sinica: Methods: There were 36 combinations of three environmental factors (3 × 3 × 4), each with three or four levels, namely temperature (16, 25, 30 °C), photoperiod (6 L:18 D, 12 L:12D, 18 L:6D), and salinity (50, 100, 150, 200 ...

    Abstract Background: Artemia sinica
    Methods: There were 36 combinations of three environmental factors (3 × 3 × 4), each with three or four levels, namely temperature (16, 25, 30 °C), photoperiod (6 L:18 D, 12 L:12D, 18 L:6D), and salinity (50, 100, 150, 200 PSU). In each treatment, 48 to 80 pairs of
    Results: Temperature, photoperiod, salinity, and their interactions significantly affected the lifespan and reproduction of
    MeSH term(s) Animals ; Female ; Artemia ; Anostraca ; Temperature ; Photoperiod ; Salinity ; Reproduction
    Language English
    Publishing date 2023-09-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2703241-3
    ISSN 2167-8359 ; 2167-8359
    ISSN (online) 2167-8359
    ISSN 2167-8359
    DOI 10.7717/peerj.15945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The role of Chinese medicine in COVID-19 pneumonia: A systematic review and meta-analysis.

    Sun, Chun-Yang / Sun, Ya-Lei / Li, Xin-Min

    The American journal of emergency medicine

    2020  Volume 38, Issue 10, Page(s) 2153–2159

    Abstract: Introduction: Chinese medicine (CM) has been used to treat Novel Coronavirus 2019 (COVID-19) pneumonia in China. This meta-analysis was conducted to evaluate the clinical efficacy and safety of CM in the treatment of COVID-19 pneumonia.: Methods: ... ...

    Abstract Introduction: Chinese medicine (CM) has been used to treat Novel Coronavirus 2019 (COVID-19) pneumonia in China. This meta-analysis was conducted to evaluate the clinical efficacy and safety of CM in the treatment of COVID-19 pneumonia.
    Methods: Randomized controlled trials (RCTs) involving CM in the treatment of COVID-19 pneumonia were identified from Cochrane Central Register of Controlled Trials, PubMed, EMBASE, Chinese National Knowledge Infrastructure, Chinese Biomedical Database, Wanfang Database and VIP Information Database. The methodological quality of trials was evaluated with Cochrane Hanadbook criteria, and the Cochrane Collaboration's Review Manager 5.3 software was used for meta-analysis.
    Results: A total of 7 valid studies involving 681 patients were included. The meta-analysis exhibited in comparison to conventional treatment, CM combined with conventional treatment significantly improved clinical efficacy (RR = 1.21, 95% CI [1.08,1.36]), and significantly increased viral nucleic acid negative conversion rate (RR = 1.49, 95% CI [1.13,1.97]). CM also prominently reduced pulmonary inflammation (RR = 1.27, 95% CI [1.12,1.44]), and improved host immune function (WBC, MD = 0.92, 95% CI [0.07,1.76]; LYM, MD = 0.33, 95% CI [0.08,0.57]; LYM%, MD = 2.90, 95% CI [2.09,3.71]; CRP, MD = -12.66, 95% CI [-24.40, -0.92]). Meanwhile, CM did not increase the incidence of adverse reactions (RR = 1.17, 95% CI [0.39,3.52]).
    Conclusion: According to the allocated data, CM has demonstrated clinical efficacy and safety on COVID-19 pneumonia, which need to be confirmed by high quality, multiple-center, large sample randomized controlled trials.
    MeSH term(s) COVID-19/drug therapy ; Drugs, Chinese Herbal/therapeutic use ; Humans ; Randomized Controlled Trials as Topic ; SARS-CoV-2/drug effects ; Treatment Outcome
    Chemical Substances Drugs, Chinese Herbal
    Keywords covid19
    Language English
    Publishing date 2020-07-08
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 605890-5
    ISSN 1532-8171 ; 0735-6757
    ISSN (online) 1532-8171
    ISSN 0735-6757
    DOI 10.1016/j.ajem.2020.06.069
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Tailoring hypervalent Nickel induced by oxygen vacancy toward enhanced oxygen evolution reaction performance in self-supporting NiFe-(oxy)hydroxides electrodes.

    Kong, Chun / Zhi, Chuang / Wu, Zirui / Yang, Wenqiang / Yang, Juan / Sun, Zhongti

    Journal of colloid and interface science

    2024  Volume 665, Page(s) 863–870

    Abstract: NiFe-(oxy)hydroxides are the most active transition metal oxide electrocatalysts for oxygen evolution reaction (OER) under the alkaline media. Herein, we controllably manipulated oxygen vacancy ( ... ...

    Abstract NiFe-(oxy)hydroxides are the most active transition metal oxide electrocatalysts for oxygen evolution reaction (OER) under the alkaline media. Herein, we controllably manipulated oxygen vacancy (V
    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 241597-5
    ISSN 1095-7103 ; 0021-9797
    ISSN (online) 1095-7103
    ISSN 0021-9797
    DOI 10.1016/j.jcis.2024.03.184
    Database MEDical Literature Analysis and Retrieval System OnLINE

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