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  1. Article ; Online: SARS-CoV-2 pandemic, influenza, and influenza-like illness epidemics: Allies or enemies?

    Ceccarelli, Giancarlo / d'Ettorre, Gabriele / Russo, Alessandro / Fabris, Silvia / Ciccozzi, Massimo / d'Ettorre, Gabriella

    Journal of medical virology

    2022  Volume 95, Issue 1, Page(s) e28148

    MeSH term(s) Humans ; SARS-CoV-2 ; Influenza, Human/epidemiology ; Pandemics ; COVID-19/epidemiology ; Virus Diseases ; Epidemics
    Language English
    Publishing date 2022-09-21
    Publishing country United States
    Document type Letter
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.28148
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  2. Article ; Online: Dysbiosis in SARS-CoV-2-Infected Patients.

    Marazzato, Massimiliano / Ceccarelli, Giancarlo / d'Ettorre, Gabriella

    Gastroenterology

    2020  Volume 160, Issue 6, Page(s) 2195

    MeSH term(s) COVID-19 ; Dysbiosis ; Hospitalization ; Humans ; Mycobiome ; Patient Discharge ; SARS-CoV-2
    Language English
    Publishing date 2020-12-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2020.12.056
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  3. Article ; Online: Early recognition of a superinfection: This is the problem in the critically ill COVID-19 patients.

    Alessandri, Francesco / d'Ettorre, Gabriella / Ciccozzi, Massimo / Migliara, Giuseppe / Baccolini, Valentina / Pugliese, Francesco / Ceccarelli, Giancarlo

    Journal of medical virology

    2023  Volume 96, Issue 1, Page(s) e29345

    MeSH term(s) Humans ; COVID-19/diagnosis ; Critical Illness ; Superinfection/diagnosis ; SARS-CoV-2
    Language English
    Publishing date 2023-12-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29345
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  4. Article ; Online: Surveillance of COVID-19 in migrant reception centres: a call for action.

    Ceccarelli, Giancarlo / Lopalco, Maurizio / d'Ettorre, Gabriele / d'Ettorre, Gabriella / Ciccozzi, Massimo

    Journal of travel medicine

    2020  Volume 28, Issue 2

    MeSH term(s) COVID-19 ; Humans ; Minority Groups ; SARS-CoV-2 ; Transients and Migrants
    Keywords covid19
    Language English
    Publishing date 2020-09-18
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taaa171
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  5. Article ; Online: Preventing influenza and influenza like illness during Covid-19 pandemic: A call for action.

    d'Ettorre, Gabriele / Ceccarelli, Giancarlo / Pinacchio, Claudia / Ciccozzi, Massimo / d'Ettorre, Gabriella

    Early human development

    2020  Volume 169, Page(s) 105156

    MeSH term(s) COVID-19 ; Humans ; Influenza A Virus, H1N1 Subtype ; Influenza, Human/epidemiology ; Influenza, Human/prevention & control ; Pandemics/prevention & control
    Keywords covid19
    Language English
    Publishing date 2020-08-12
    Publishing country Ireland
    Document type Letter
    ZDB-ID 752532-1
    ISSN 1872-6232 ; 0378-3782
    ISSN (online) 1872-6232
    ISSN 0378-3782
    DOI 10.1016/j.earlhumdev.2020.105156
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  6. Article ; Online: Comment on: Long-term outcome of dolutegravir-containing regimens according to sex: data from the ICONA study.

    Ciccullo, Arturo / Baldin, Gianmaria / Sterrantino, Gaetana / Madeddu, Giordano / D'ettorre, Gabriella / Mussini, Cristina / Di Giambenedetto, Simona

    The Journal of antimicrobial chemotherapy

    2023  Volume 78, Issue 7, Page(s) 1808–1809

    MeSH term(s) Humans ; HIV Infections/drug therapy ; Anti-HIV Agents/therapeutic use ; Oxazines/therapeutic use ; Heterocyclic Compounds, 3-Ring/adverse effects ; Pyridones/therapeutic use
    Chemical Substances dolutegravir (DKO1W9H7M1) ; Anti-HIV Agents ; Oxazines ; Heterocyclic Compounds, 3-Ring ; Pyridones
    Language English
    Publishing date 2023-05-22
    Publishing country England
    Document type Research Support, Non-U.S. Gov't ; Letter ; Comment
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkad151
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    Zs.MO 124: Show issues

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  7. Article ; Online: Right to Occupational Safety: Prevalence of Latent Tuberculosis Infection in Healthcare Workers. A 1-Year Retrospective Survey Carried out at Hospital of Lecce (Italy).

    d'Ettorre, Gabriele / Karaj, Stela / Piscitelli, Prisco / Maiorano, Osvaldo / Attanasi, Carmen / Tornese, Roberta / Carluccio, Eugenia / Giannuzzi, Paolo / Greco, Enrico / Ceccarelli, Giancarlo / d'Ettorre, Gabriella / Lobreglio, Giambattista / Congedo, Pierpaolo / Broccolo, Francesco / Miani, Alessandro

    Epidemiologia (Basel, Switzerland)

    2023  Volume 4, Issue 4, Page(s) 454–463

    Abstract: Background: Prevention of latent tuberculosis infection (LTBI) in healthcare workers (HCWs) to ensure the "Right to Occupational Safety" is a special challenge globally, as HCWs have a higher risk of acquiring the infection in hospital settings because ... ...

    Abstract Background: Prevention of latent tuberculosis infection (LTBI) in healthcare workers (HCWs) to ensure the "Right to Occupational Safety" is a special challenge globally, as HCWs have a higher risk of acquiring the infection in hospital settings because of frequent close exposure to patients suffering from tuberculosis (TB).
    Methods: Aretrospective study was performed with the aim of assessing the prevalence of LTBI related to demographical and occupational risk factors among HCWs employed in a large hospital in Italy. The study involved 1461 HCWs screened for LTBI by Mantoux tuberculin skin test (TST) and then confirmed with Interferon Gamma Release Assay (IGRA) test in case of positivity. Immunosuppressed and BGC-vaccinated workers were tested directly with IGRA.
    Results: LTBI was diagnosed in 4.1% of the HCWs and the prevalence resulted lower than other studies conducted in low TB incidence countries. The variables significantly linked with higher frequency of the infection were: age ≥40 years (OR = 3.14; 95% CI: 1.13-8.74;
    Conclusions: screening of HCWs for LTBI should be always considered in routinely occupational surveillance in order to early diagnose the infection and prevent its progression. Safety policies in hospital settings centered on workers' training on TB prevention is crucial to minimize LTBI occurrence in HCWs.
    Language English
    Publishing date 2023-10-31
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-3986
    ISSN (online) 2673-3986
    DOI 10.3390/epidemiologia4040038
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  8. Article ; Online: Time to Effective Therapy Is an Important Determinant of Survival in Bloodstream Infections Caused by Vancomycin-Resistant

    Russo, Alessandro / Picciarella, Alice / Russo, Roberta / d'Ettorre, Gabriella / Ceccarelli, Giancarlo

    International journal of molecular sciences

    2022  Volume 23, Issue 19

    Abstract: Enterococcal bloodstream infections (EBSI) caused by vancomycin-resistant enterococci (VRE) are associated with a significant rate of unfavorable outcomes. No definitive data have been reported about the association between delayed antibiotic therapy and ...

    Abstract Enterococcal bloodstream infections (EBSI) caused by vancomycin-resistant enterococci (VRE) are associated with a significant rate of unfavorable outcomes. No definitive data have been reported about the association between delayed antibiotic therapy and mortality. In this prospective observational study in three large hospitals in Italy (from August 2016 to April 2021), all consecutive hospitalized patients with a confirmed diagnosis of hospital-acquired monomicrobial BSI caused by VRE—with no evidence of endocarditis—were analyzed. Cox regression analysis showed that risk factors independently associated with 30-day mortality were age (HR 2.98, CI95% 1.44−6.81, p = 0.002), chronic kidney disease (HR 5.21, CI95% 1.48−22.23, p = 0.001), oncologic disease (HR 2.81, CI95% 1.45−19.8, p = 0.005), and intensive care unit admission (HR 3.71, CI95% 2.23−7.99, p < 0.001). Conversely, early effective therapy was associated with survival (HR 0.32, CI95% 0.38−0.76, p < 0.001). The administration of early effective antibiotic therapy within 48 h from blood culture collection was associated with 30-day mortality rates lower than 33%. Time from blood culture collection to appropriate therapy was an independent predictor of 30-day mortality in patients with EBSI caused by VRE. Based on these data, clinicians should start effective antibiotic therapy as soon as possible, preferably within the first 48 h from blood culture collection. Treatment strategies allowing the early delivery of in vitro active antibiotics are urgently needed, especially in critically ill patients at risk of VRE bacteremia.
    MeSH term(s) Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Bacteremia/drug therapy ; Gram-Positive Bacterial Infections/drug therapy ; Humans ; Retrospective Studies ; Vancomycin/pharmacology ; Vancomycin/therapeutic use ; Vancomycin Resistance ; Vancomycin-Resistant Enterococci
    Chemical Substances Anti-Bacterial Agents ; Vancomycin (6Q205EH1VU)
    Language English
    Publishing date 2022-10-07
    Publishing country Switzerland
    Document type Journal Article ; Observational Study
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms231911925
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  9. Article: The Epidemiology of Anal Human Papillomavirus (HPV) in HIV-Positive and HIV-Negative Women and Men: A Ten-Year Retrospective Observational Study in Rome (Italy).

    Fracella, Matteo / Oliveto, Giuseppe / Roberto, Piergiorgio / Cinti, Lilia / Gentile, Massimo / Coratti, Eleonora / D'Ettorre, Gabriella / Cavallari, Eugenio Nelson / Romano, Francesco / Santinelli, Letizia / Maddaloni, Luca / Frasca, Federica / Scagnolari, Carolina / Antonelli, Guido / Pierangeli, Alessandra

    Pathogens (Basel, Switzerland)

    2024  Volume 13, Issue 2

    Abstract: Human papillomaviruses (HPVs) commonly infect the anogenital mucosa; most infections are transient, but a fraction of those caused by high-risk (HR) types persist and may lead to anogenital cancer. The epidemiology of HPV genotypes in anal infections in ... ...

    Abstract Human papillomaviruses (HPVs) commonly infect the anogenital mucosa; most infections are transient, but a fraction of those caused by high-risk (HR) types persist and may lead to anogenital cancer. The epidemiology of HPV genotypes in anal infections in groups at different risk for anal cancer has not been well described in Italy. This retrospective study reports the results of HPV DNA testing and complete genotyping performed on anal swabs from 691 female and male patients attending proctology clinics in Rome during 2012-2021; one-third had repeated testing. Cumulative HPV positivity in 1212 anal swabs was approximately 60%, was not age related, and showed an increasing trend over the study period. HPV rates differed significantly by sex and HIV status: HIV-negative women had the lowest (43.6%) and HIV-positive men the highest (83.5%) HPV prevalence. HIV-positive men had more oncogenic HPV genotypes detected, more multiple infections, and the highest frequency of persistent infections. Two-thirds of all infections were vaccine-preventable. This study found that anal HPV infection rates are still elevated and even increasing in groups at low and high risk of developing anal cancer. Prevention programs need to be improved to reduce rates of anal infection in young women and men.
    Language English
    Publishing date 2024-02-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens13020163
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  10. Article ; Online: Early antibiotic treatment in emergency department: the critical balance.

    Russo, Alessandro / Venditti, Mario / Ceccarelli, Giancarlo / Mastroianni, Claudio Maria / d'Ettorre, Gabriella

    Internal and emergency medicine

    2021  Volume 16, Issue 7, Page(s) 1743–1745

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Emergency Service, Hospital ; Humans
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-06-06
    Publishing country Italy
    Document type Journal Article ; Comment
    ZDB-ID 2454173-4
    ISSN 1970-9366 ; 1828-0447
    ISSN (online) 1970-9366
    ISSN 1828-0447
    DOI 10.1007/s11739-021-02779-9
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