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  1. Book ; Conference proceedings: Neuropathic pain

    Koltzenburg, Martin

    bench to bedside ; proceedings of a symposium held at the Royal Society of Medicine, London, UK, on 21 January 2005

    (International congress and symposium series ; 259)

    2005  

    Title variant Neuropathic pain: bench to bedside
    Author's details ed. by Martin Koltzenburg
    Series title International congress and symposium series ; 259
    International congress and symposium series / Royal Society of Medicine
    Collection International congress and symposium series / Royal Society of Medicine
    Language English
    Size V, 73 S. : Ill., graph. Darst.
    Publisher Royal Soc. of Med. Press
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT014483810
    ISBN 1-85315-625-6 ; 978-1-85315-625-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2008 A 1514 order for loan Magazin

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  2. Book ; Conference proceedings: Neuropathic pain - strategies for successful pain management

    Koltzenburg, Martin

    [proceedings of the Symposium "Neuropathic Pain: Strategies for Successful Patient Management", which was held on Monday, 28 October 2002, in Vienna, Austria]

    (European journal of neurology ; 11, Suppl. 1)

    2004  

    Institution Symposium Neuropathic Pain: Strategies for Successful Patient Management
    Author's details guest ed.: M. Koltzenburg
    Series title European journal of neurology ; 11, Suppl. 1
    Collection
    Language English
    Size 30 S. : Ill., graph. Darst.
    Publisher Blackwell Science
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT014006086
    Database Catalogue ZB MED Medicine, Health

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    Zs A 4738 -11,Suppl.1- not available for loan Zeitschriften-Lesesaal

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  3. Article ; Online: Long-interval afferent inhibition measurement using two different methods: Normative values, repeatability and reliability.

    Boran, Hürrem Evren / Alaydın, Halil Can / Kılınç, Hasan / Tankişi, Hatice / Samusyte, Ginte / Howells, James / Koltzenburg, Martin / Cengiz, Bülent

    Neurophysiologie clinique = Clinical neurophysiology

    2024  Volume 54, Issue 1, Page(s) 102940

    Abstract: Background: The mechanism of Short-Latency Afferent Inhibition (SAI) is relatively well understood. In contrast, Long-Latency Afferent Inhibition (LAI) has not been as extensively studied as SAI, and its underlying mechanism remains unclear.: ... ...

    Abstract Background: The mechanism of Short-Latency Afferent Inhibition (SAI) is relatively well understood. In contrast, Long-Latency Afferent Inhibition (LAI) has not been as extensively studied as SAI, and its underlying mechanism remains unclear.
    Objective/hypothesis: This study had two primary objectives: first, to determine the optimal ISIs for LAI measured by amplitude changes (A-LAI) using high-resolution ISI ranges; and second, to compare measurements of LAI by threshold-tracking (T-LAI).
    Methods: Twenty-eight healthy volunteers (12 males aged 24- 45 years) participated in the study. Paired peripheral electrical and transcranial magnetic stimulation (TMS) stimuli (TS1mv) were applied at varying (ISIs)- 100, 200, 250, 300, 350, 400, 450, 500, 550, 600, 700, 800, 900, 1000 ms.
    Results: Both A-LAI and T-LAI showed that LAI decreased progressively from a peak at 200 or 250 ms to 1000 ms. Using the A-LAI method, pronounced inhibition was observed at three specific ISIs: 100 ms, 250 ms and 450 ms. When A-LAI values were converted to equivalent threshold changes, they did not differ significantly from T-LAI. Reliability at distinguishing individuals, as indicated by intraclass correlation coefficient (ICC) was greater for A-LAI, with a peak value of 0.82 at 250 ms.
    Conclusion(s): The study demonstrates that ISIs of 100 ms and 250 ms can be reliably used in amplitude measurement LAI. The study demonstrates that both LAI measurements record a similar decline of inhibition with increasing ISI.
    MeSH term(s) Male ; Humans ; Afferent Pathways/physiology ; Reproducibility of Results ; Neural Inhibition/physiology ; Reaction Time/physiology ; Transcranial Magnetic Stimulation ; Evoked Potentials, Motor/physiology
    Language English
    Publishing date 2024-02-20
    Publishing country France
    Document type Journal Article
    ZDB-ID 639421-8
    ISSN 1769-7131 ; 0987-7053
    ISSN (online) 1769-7131
    ISSN 0987-7053
    DOI 10.1016/j.neucli.2023.102940
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Caffeine and cortical excitability, as measured with paired-pulse transcranial magnetic stimulation.

    Strunge, Kristine / Bostock, Hugh / Howells, James / Cengiz, Bülent / Samusyte, Gintaute / Koltzenburg, Martin / Tankisi, Hatice

    Muscle & nerve

    2023  Volume 69, Issue 2, Page(s) 206–212

    Abstract: Introduction/aims: The transcranial magnetic stimulation tests of short-interval intracortical inhibition (SICI) by both conventional amplitude measurements (A-SICI) and threshold-tracking (T-SICI) are important methods to investigate intracortical ... ...

    Abstract Introduction/aims: The transcranial magnetic stimulation tests of short-interval intracortical inhibition (SICI) by both conventional amplitude measurements (A-SICI) and threshold-tracking (T-SICI) are important methods to investigate intracortical inhibitory circuits, and T-SICI has been proposed to aid the diagnosis of amyotrophic lateral sclerosis. Beverages containing caffeine are widely consumed, and caffeine has been reported to affect cortical excitability. The aim of this study was to determine whether these SICI tests are affected by caffeine.
    Methods: Twenty-four healthy subjects (13 females, 11 males, aged from 19 to 31, mean: 26.2 ± 2.4 years) were studied in a single fixed-dose randomized double-blind placebo-controlled cross-over trial of 200 mg caffeine or placebo ingested as chewing gum. A-SICI and T-SICI, using parallel tracking (T-SICIp), were performed before and after chewing gum.
    Results: There was no significant change in SICI parameters after placebo in A-SICI (p > .10) or T-SICIp (p > .30), and no significant effect of caffeine was found on A-SICI (p > .10) or T-SICIp (p > .50) for any of the interstimulus intervals.
    Discussion: There is no need for caffeine abstention before measurements of SICI by either the T-SICI or A-SICI measurements.
    MeSH term(s) Female ; Humans ; Male ; Caffeine/pharmacology ; Chewing Gum ; Cortical Excitability ; Evoked Potentials, Motor/physiology ; Motor Cortex/physiology ; Neural Inhibition/physiology ; Transcranial Magnetic Stimulation/methods ; Young Adult ; Adult
    Chemical Substances Caffeine (3G6A5W338E) ; Chewing Gum
    Language English
    Publishing date 2023-12-21
    Publishing country United States
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 438353-9
    ISSN 1097-4598 ; 0148-639X
    ISSN (online) 1097-4598
    ISSN 0148-639X
    DOI 10.1002/mus.28027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 551: Show issues

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  5. Book ; Thesis: Aktivierung sakraler viszeraler Afferenzen durch mechanische Reizung und experimentelle Entzündung der Harnblase

    Koltzenburg, Martin

    1989  

    Author's details vorgelegt von Martin Koltzenburg
    Size 136 S. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Kiel, Univ., Diss., 1989
    HBZ-ID HT003712098
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    91 D 773 order for loan Magazin

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  6. Article ; Online: Short interval intracortical inhibition: Variability of amplitude and threshold-tracking measurements with 6 or 10 stimuli per point.

    Tankisi, Hatice / Cengiz, Bülent / Samusyte, Gintaute / Howells, James / Koltzenburg, Martin / Bostock, Hugh

    Neurophysiologie clinique = Clinical neurophysiology

    2022  Volume 52, Issue 2, Page(s) 170–173

    Abstract: Reduced short-interval intracortical inhibition (SICI) in motor neuron disease has been demonstrated by amplitude changes (A-SICI) and threshold-tracking (T-SICI) using 10 stimuli per inter-stimulus interval (ISI). To test whether fewer stimuli would ... ...

    Abstract Reduced short-interval intracortical inhibition (SICI) in motor neuron disease has been demonstrated by amplitude changes (A-SICI) and threshold-tracking (T-SICI) using 10 stimuli per inter-stimulus interval (ISI). To test whether fewer stimuli would suffice, A-SICI and T-SICI were recorded twice from 30 healthy subjects using 6 and 10 stimuli per ISI. Using fewer stimuli increased mean A-SICI variances by 23.8% but the 7.3% increase in T-SICI variance was not significant. We conclude that our new parallel threshold-tracking SICI protocol, with 6 stimuli per ISI, can reduce time and stimulus numbers by 40% without appreciable loss of accuracy.
    MeSH term(s) Electromyography/methods ; Evoked Potentials, Motor/physiology ; Humans ; Motor Cortex/physiology ; Neural Inhibition/physiology ; Transcranial Magnetic Stimulation/methods
    Language English
    Publishing date 2022-01-06
    Publishing country France
    Document type Journal Article
    ZDB-ID 639421-8
    ISSN 1769-7131 ; 0987-7053
    ISSN (online) 1769-7131
    ISSN 0987-7053
    DOI 10.1016/j.neucli.2021.11.006
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  7. Article ; Online: Letter to the Editor re "Complete Foot Drop With Normal Electrodiagnostic Studies: Sunderland 'Zero' Ischemic Conduction Block of the Common Peroneal Nerve" by Peters and Colleagues.

    Cornblath, David R / Kiernan, Matthew C / Kimura, Jun / Koltzenburg, Martin / Lewis, Richard A / Parry, Gareth J / Pollard, John D / Sumner, Austin J

    Annals of plastic surgery

    2022  Volume 89, Issue 4, Page(s) 343

    MeSH term(s) Humans ; Neural Conduction ; Peroneal Nerve ; Peroneal Neuropathies/diagnosis
    Language English
    Publishing date 2022-06-07
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 423835-7
    ISSN 1536-3708 ; 0148-7043
    ISSN (online) 1536-3708
    ISSN 0148-7043
    DOI 10.1097/SAP.0000000000003245
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    Zs.A 1419: Show issues Location:
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  8. Article ; Online: Three different short-interval intracortical inhibition methods in early diagnosis of amyotrophic lateral sclerosis.

    Tankisi, Hatice / Pia, Hossein / Strunge, Kristine / Howells, James / Cengiz, Bülent / Samusyte, Gintaute / Koltzenburg, Martin / Fuglsang-Frederiksen, Anders / Bostock, Hugh

    Amyotrophic lateral sclerosis & frontotemporal degeneration

    2022  Volume 24, Issue 1-2, Page(s) 139–147

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) Humans ; Amyotrophic Lateral Sclerosis/diagnosis ; Transcranial Magnetic Stimulation/methods ; Evoked Potentials, Motor/physiology ; Motor Neuron Disease ; Early Diagnosis ; Neural Inhibition/physiology
    Language English
    Publishing date 2022-07-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2705049-X
    ISSN 2167-9223 ; 2167-8421
    ISSN (online) 2167-9223
    ISSN 2167-8421
    DOI 10.1080/21678421.2022.2101926
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  9. Article ; Online: Conventional and Threshold-Tracking Transcranial Magnetic Stimulation Tests for Single-handed Operation.

    Tankisi, Hatice / Howells, James / Cengiz, Bülent / Samusyte, Gintaute / Koltzenburg, Martin / Bostock, Hugh

    Journal of visualized experiments : JoVE

    2021  , Issue 174

    Abstract: Most single-pulse transcranial magnetic stimulation (TMS) parameters (e.g., motor threshold, stimulus-response function, cortical silent period) are used to examine corticospinal excitability. Paired-pulse TMS paradigms (e.g., short- and long-interval ... ...

    Abstract Most single-pulse transcranial magnetic stimulation (TMS) parameters (e.g., motor threshold, stimulus-response function, cortical silent period) are used to examine corticospinal excitability. Paired-pulse TMS paradigms (e.g., short- and long-interval intracortical inhibition (SICI/LICI), short-interval intracortical facilitation (SICF), and short- and long-latency afferent inhibition (SAI/LAI)) provide information about intracortical inhibitory and facilitatory networks. This has long been done by the conventional TMS method of measuring changes in the size of the motor-evoked potentials (MEPs) in response to stimuli of constant intensity. An alternative threshold-tracking approach has recently been introduced whereby the stimulus intensity for a target amplitude is tracked. The diagnostic utility of threshold-tracking SICI in amyotrophic lateral sclerosis (ALS) has been shown in previous studies. However, threshold-tracking TMS has only been used in a few centers, in part due to the lack of readily available software but also perhaps due to uncertainty over its relationship to conventional single- and paired-pulse TMS measurements. A menu-driven suite of semi-automatic programs has been developed to facilitate the broader use of threshold-tracking TMS techniques and to enable direct comparisons with conventional amplitude measurements. These have been designed to control three types of magnetic stimulators and allow recording by a single operator of the common single- and paired-pulse TMS protocols. This paper shows how to record a number of single- and paired-pulse TMS protocols on healthy subjects and analyze the recordings. These TMS protocols are fast and easy to perform and can provide useful biomarkers in different neurological disorders, particularly neurodegenerative diseases such as ALS.
    MeSH term(s) Electromyography ; Evoked Potentials, Motor ; Humans ; Motor Cortex ; Neural Inhibition ; Transcranial Magnetic Stimulation
    Language English
    Publishing date 2021-08-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Video-Audio Media
    ZDB-ID 2259946-0
    ISSN 1940-087X ; 1940-087X
    ISSN (online) 1940-087X
    ISSN 1940-087X
    DOI 10.3791/62787
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  10. Article ; Online: Short latency afferent inhibition: comparison between threshold-tracking and conventional amplitude recording methods.

    Cengiz, Bülent / Boran, H Evren / Alaydın, Halil Can / Tankisi, Hatice / Samusyte, Gintaute / Howells, James / Koltzenburg, Martin / Bostock, Hugh

    Experimental brain research

    2022  Volume 240, Issue 4, Page(s) 1241–1247

    Abstract: Short-latency afferent inhibition (SAI), which is conventionally measured as a reduction in motor evoked potential amplitude (A-SAI), is of clinical interest as a potential biomarker for cognitive impairment. Since threshold-tracking has some advantages ... ...

    Abstract Short-latency afferent inhibition (SAI), which is conventionally measured as a reduction in motor evoked potential amplitude (A-SAI), is of clinical interest as a potential biomarker for cognitive impairment. Since threshold-tracking has some advantages for clinical studies of short-interval cortical inhibition, we have compared A-SAI with a threshold-tracking alternative method (T-SAI). In the T-SAI method, inhibition was calculated by tracking the required TMS intensity for the targeted MEP amplitude (200 uV) both for the test (TMS only) and paired (TMS and peripheral stimulation) stimuli. A-SAI and T-SAI were recorded from 31 healthy subjects using ten stimuli at each of 12 inter-stimulus intervals, once in the morning and again in the afternoon. There were no differences between morning and afternoon recordings. When A-SAI was normalized by log conversion it was closely related to T-SAI. Between subjects, variability was similar for the two techniques, but within-subject variability was significantly smaller for normalized A-SAI. Conventional amplitude measurements appear more sensitive for detecting changes within-subjects, such as in interventional studies, but threshold-tracking may be as sensitive as detecting abnormal SAI in a patient.
    MeSH term(s) Afferent Pathways/physiology ; Electromyography/methods ; Evoked Potentials, Motor/physiology ; Humans ; Motor Cortex/physiology ; Neural Inhibition/physiology ; Reaction Time/physiology ; Transcranial Magnetic Stimulation/methods
    Language English
    Publishing date 2022-02-22
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1201-4
    ISSN 1432-1106 ; 0014-4819
    ISSN (online) 1432-1106
    ISSN 0014-4819
    DOI 10.1007/s00221-022-06327-5
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