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Article ; Online: The use of copper to help prevent transmission of SARS-coronavirus and influenza viruses. A general review.

Cortes, Aaron A / Zuñiga, Jorge M

Diagnostic microbiology and infectious disease

2020 Volume 98, Issue 4, Page(s) 115176

Abstract: The SARS-CoV-2 is the causative agent of the COVID-19 disease, a severe acute respiratory syndrome-coronavirus (SARS-CoV). Its main transmission pathway is through large respiratory droplets, as well as direct and indirect contact. Copper in different ... ...

Abstract	The SARS-CoV-2 is the causative agent of the COVID-19 disease, a severe acute respiratory syndrome-coronavirus (SARS-CoV). Its main transmission pathway is through large respiratory droplets, as well as direct and indirect contact. Copper in different formats has been used in research and clinical settings to reduce the risk of bacterial and viral contamination. Therefore, this review aims to search for evidence about the biocidal properties of copper over the Coronaviridae family. A literature review was performed using PubMed and Ovid servers without date or language restrictions. The search was carried out on March 7, 2020, using the following search terms: [Copper] Coronavirus OR CoV OR SARS OR MERS OR Influenza. Copper destroys the replication and propagation abilities of SARS-CoV, influenza, and other respiratory viruses, having high potential disinfection in hospitals, communities, and households. Copper can eliminate pathogenic organisms such as coronavirus bacterial strains, influenza virus, HIV, and fungi after a short period of exposure. Copper seems to be an effective and low-cost complementary strategy to help reduce the transmission of several infectious diseases by limiting nosocomial infectious transmission. Copper oxide or nanocompounds may be used as filters, face masks, clothing, and hospital common surfaces to reduce viruses and bacterial incubation.
MeSH term(s)	Betacoronavirus/drug effects ; COVID-19 ; Copper/pharmacology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Disinfectants/pharmacology ; Humans ; Influenza, Human/prevention & control ; Influenza, Human/transmission ; Orthomyxoviridae/drug effects ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; SARS-CoV-2
Chemical Substances	Disinfectants ; Copper (789U1901C5) ; cuprous oxide (T8BEA5064F)
Keywords	covid19
Language	English
Publishing date	2020-08-15
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	604920-5
ISSN	1879-0070 ; 0732-8893
ISSN (online)	1879-0070
ISSN	0732-8893
DOI	10.1016/j.diagmicrobio.2020.115176
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Article ; Online: Molecular and morphological data suggest a new species of big-eared bat (Vespertilionidae: Corynorhinus) endemic to northeastern Mexico.

López-Cuamatzi, Issachar L / Ortega, Jorge / Ospina-Garcés, Sandra M / Zúñiga, Gerardo / MacSwiney G, M Cristina

PloS one

2024 Volume 19, Issue 2, Page(s) e0296275

Abstract: Corynorhinus mexicanus is an insectivorous bat endemic to Mexico that inhabits the high and humid regions of the Sierra Madre Oriental (SMO), the Trans-Mexican Volcanic Belt (TMVB), and the Sierra Madre Occidental (SMOC). A previous study suggested that ... ...

Abstract	Corynorhinus mexicanus is an insectivorous bat endemic to Mexico that inhabits the high and humid regions of the Sierra Madre Oriental (SMO), the Trans-Mexican Volcanic Belt (TMVB), and the Sierra Madre Occidental (SMOC). A previous study suggested that C. mexicanus could be a cryptic species complex due to the genetic divergence observed between specimens from the TMVB and SMOC. The present study implemented phylogenetic, population genetics, and morphological analyses to evaluate the hypothesis that C. mexicanus is a species complex. The phylogenetic analysis indicated that C. mexicanus is a polyphyletic species composed of three indirectly related lineages. The estimated divergence times for the lineages suggest that they first originated during the Pliocene, while the second and third shared a common ancestor with C. townsendii 1.55 million years ago, and diverged 600,000 years ago during the Middle Pleistocene. The population genetics analysis reveals the SMO lineage of C. mexicanus is an isolated genetic group and highly diverged from the rest of lineages (SMOC and TMVB). The morphological analyses showed variation in the skull and mandible associated with the lineages and sex of the specimens, highlighting a difference in mandible shape between the specimens of the SMO and the rest of C. mexicanus. The results of this study suggest the presence of an undescribed species of the genus Corynorhinus.
MeSH term(s)	Animals ; Phylogeny ; Chiroptera/genetics ; Mexico ; Genetics, Population
Language	English
Publishing date	2024-02-21
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0296275
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Article ; Online: The role of additive manufacturing and antimicrobial polymers in the COVID-19 pandemic.

Zuniga, Jorge M / Cortes, Aaron

Expert review of medical devices

2020 Volume 17, Issue 6, Page(s) 477–481

Keywords	covid19
Language	English
Publishing date	2020-04-30
Publishing country	England
Document type	Editorial
ZDB-ID	2250857-0
ISSN	1745-2422 ; 1743-4440
ISSN (online)	1745-2422
ISSN	1743-4440
DOI	10.1080/17434440.2020.1756771
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Article ; Online: Comparison of virtual reality to physical box and blocks on cortical an neuromuscualar activations in young adults.

Parker, Sheridan M / Ricks, Brian / Zuniga, Jorge / Knarr, Brian A

Scientific reports

2023 Volume 13, Issue 1, Page(s) 16567

Abstract: The purpose of this study was to assess the changes in neural activations when performing the box and block test (BBT) in virtual reality (VR) compared to the physical BBT. Young healthy participants performed three trials of the BBT with their left and ... ...

Abstract	The purpose of this study was to assess the changes in neural activations when performing the box and block test (BBT) in virtual reality (VR) compared to the physical BBT. Young healthy participants performed three trials of the BBT with their left and right hands in both the VR BBT, using VR hand controllers, and physical BBT conditions. Electromyography sensors were placed on the upper extremity of both arms and functional near-infrared spectroscopy was used to measure motor cortex activations throughout each condition. While a reduction in BBT score and increased wrist extensor neuromuscular activity is exhibited during the VR condition, there is no statistical difference in motor cortex activation between the two BBT conditions. This work provides a basis for exploring cortical and neuromuscular responses to VR in patient populations.
MeSH term(s)	Humans ; Young Adult ; Upper Extremity ; Hand ; Wrist ; Psychomotor Performance/physiology ; Virtual Reality
Language	English
Publishing date	2023-10-02
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-43073-2
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Article ; Online: Laterality Index Calculations in a Control Study of Functional Near Infrared Spectroscopy.

Borrell, Jordan A / Fraser, Kaitlin / Manattu, Arun Karumattu / Zuniga, Jorge M

Brain topography

2023 Volume 36, Issue 2, Page(s) 210–222

Abstract: Hemispheric dominance has been used to understand the influence of central and peripheral neural damage on the motor function of individuals with stroke, cerebral palsy, and limb loss. It has been well established that greater activation occurs in the ... ...

Abstract	Hemispheric dominance has been used to understand the influence of central and peripheral neural damage on the motor function of individuals with stroke, cerebral palsy, and limb loss. It has been well established that greater activation occurs in the contralateral hemisphere to the side of the body used to perform the task. However, there is currently a large variability in calculation procedures for brain laterality when using functional near-infrared spectroscopy (fNIRS) as a non-invasive neuroimaging tool. In this study, we used fNIRS to measure brain activity over the left and right sensorimotor cortices while participants (n = 20, healthy and uninjured) performed left and right-hand movement tasks. Then, we analyzed the fNIRS data using two different processing pipelines (block averaging or general linear model [GLM]), two different criteria of processing for negative values (include all beta values or include only positive beta values), and three different laterality index (LI) formulas. The LI values produced using the block averaging analysis indicated an expected contralateral dominance with some instances of bilateral dominance, which agreed with the expected contralateral activation. However, the inclusion criteria nor the LI formulas altered the outcome. The LI values produced using the GLM analysis displayed a robust left hemisphere dominance regardless of the hand performing the task, which disagreed with the expected contralateral activation but did provide instances of correctly identifying brain laterality. In conclusion, both analysis pipelines were able to correctly determine brain laterality, but processes to account for negative beta values were recommended especially when utilizing the GLM analysis to determine brain laterality.
MeSH term(s)	Humans ; Spectroscopy, Near-Infrared/methods ; Functional Laterality/physiology ; Hand ; Sensorimotor Cortex ; Upper Extremity ; Brain Mapping/methods
Language	English
Publishing date	2023-02-09
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	1078442-1
ISSN	1573-6792 ; 0896-0267
ISSN (online)	1573-6792
ISSN	0896-0267
DOI	10.1007/s10548-023-00942-3
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Article ; Online: Airy beam propagation: autofocusing, quasi-adiffractional propagation, and self-healing.

Anaya-Contreras, Jorge A / Zúñiga-Segundo, Arturo / Moya-Cessa, Héctor M

Journal of the Optical Society of America. A, Optics, image science, and vision

2021 Volume 38, Issue 5, Page(s) 711–718

Abstract: We study the propagation of superpositions of Airy beams and show that, by adequately choosing the parameters in the superposition, effects as opposite as autofocusing and quasi-adiffractional propagation may be obtained. We also give a simple analytical ...

Abstract	We study the propagation of superpositions of Airy beams and show that, by adequately choosing the parameters in the superposition, effects as opposite as autofocusing and quasi-adiffractional propagation may be obtained. We also give a simple analytical expression for free propagation of any initial field, based on so-called number states (eigenstates of the quantum harmonic oscillator), that allows us to study their self-healing properties.
Language	English
Publishing date	2021-05-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	283633-6
ISSN	1520-8532 ; 1084-7529 ; 0740-3232
ISSN (online)	1520-8532
ISSN	1084-7529 ; 0740-3232
DOI	10.1364/JOSAA.418533
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Article ; Online: Early Exercise Through Telerehabilitation After Bariatric Surgery: Is It Feasible?

Pino-Zúñiga, Johanna / Olivares, Mariela / Muñoz, Giselle / Boza, Camilo / Duque, Camilo / Cancino-López, Jorge

Obesity surgery

2024

Abstract: Purpose: The feasibility of early telerehabilitation after bariatric surgery is unknown. The objective of this study was to assess the feasibility and perception of engaging in the online exercise protocol in patients during the first month after ... ...

Abstract	Purpose: The feasibility of early telerehabilitation after bariatric surgery is unknown. The objective of this study was to assess the feasibility and perception of engaging in the online exercise protocol in patients during the first month after bariatric surgery. Material and methods: A total of 67 patients, enrolled in a telerehabilitation program following bariatric surgery, completed a survey assessing their perception of the intensity, discomfort, and safety during exercise sessions. Results: Forty percent of participants began exercising between 5 and 10 days after surgery. Seventy-one percent of patients did not experience discomfort during the first month of exercise, and those who reported discomfort mainly mentioned dizziness and abdominal pain. No significant differences were found in the presence of discomfort among different types of surgeries performed. There was a significant difference in the presence of discomfort between patients who started exercising before and after 15 days of surgery, with less discomfort reported in the group that started after 15 days. Ninety-eight percent of patients felt safe during online exercise sessions. Most participants perceived the intensity of the sessions as moderate. The most frequently mentioned benefits of exercise were increased energy, mood, and feeling more active. Conclusion: Telerehabilitation conducted during the first month after bariatric surgery was feasible and well tolerated by patients, providing a safe alternative for those patients who face difficulties with in-person interventions.
Language	English
Publishing date	2024-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	1070827-3
ISSN	1708-0428 ; 0960-8923
ISSN (online)	1708-0428
ISSN	0960-8923
DOI	10.1007/s11695-024-07185-6
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Article ; Online: Comparison of virtual reality to physical box and blocks on cortical an neuromuscualar activations in young adults

Sheridan M. Parker / Brian Ricks / Jorge Zuniga / Brian A. Knarr

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Volume 11

Abstract: Abstract The purpose of this study was to assess the changes in neural activations when performing the box and block test (BBT) in virtual reality (VR) compared to the physical BBT. Young healthy participants performed three trials of the BBT with their ... ...

Abstract	Abstract The purpose of this study was to assess the changes in neural activations when performing the box and block test (BBT) in virtual reality (VR) compared to the physical BBT. Young healthy participants performed three trials of the BBT with their left and right hands in both the VR BBT, using VR hand controllers, and physical BBT conditions. Electromyography sensors were placed on the upper extremity of both arms and functional near-infrared spectroscopy was used to measure motor cortex activations throughout each condition. While a reduction in BBT score and increased wrist extensor neuromuscular activity is exhibited during the VR condition, there is no statistical difference in motor cortex activation between the two BBT conditions. This work provides a basis for exploring cortical and neuromuscular responses to VR in patient populations.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The use of copper to help prevent transmission of SARS-coronavirus and influenza viruses. A general review

Cortes, Aaron A / Zuñiga, Jorge M

Diagn Microbiol Infect Dis

Abstract	The SARS-CoV-2 is the causative agent of the COVID-19 disease, a severe acute respiratory syndrome-coronavirus (SARS-CoV). Its main transmission pathway is through large respiratory droplets, as well as direct and indirect contact. Copper in different formats has been used in research and clinical settings to reduce the risk of bacterial and viral contamination. Therefore, this review aims to search for evidence about the biocidal properties of copper over the Coronaviridae family. A literature review was performed using PubMed and Ovid servers without date or language restrictions. The search was carried out on March 7, 2020, using the following search terms: [Copper] Coronavirus OR CoV OR SARS OR MERS OR Influenza. Copper destroys the replication and propagation abilities of SARS-CoV, influenza, and other respiratory viruses, having high potential disinfection in hospitals, communities, and households. Copper can eliminate pathogenic organisms such as coronavirus bacterial strains, influenza virus, HIV, and fungi after a short period of exposure. Copper seems to be an effective and low-cost complementary strategy to help reduce the transmission of several infectious diseases by limiting nosocomial infectious transmission. Copper oxide or nanocompounds may be used as filters, face masks, clothing, and hospital common surfaces to reduce viruses and bacterial incubation.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #713149
Database	COVID19

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Article ; Online: Characterization of Antimicrobial Poly(Lactic Acid)- and Polyurethane-Based Materials Enduring Closed-Loop Recycling with Applications in Space.

D'Ovidio, Andrew J / Knarr, Brian / Blanchard, Alexander J / Bennett, Gregory W / Leiva, William / Duan, Bin / Zuniga, Jorge M

Polymers

2024 Volume 16, Issue 5

Abstract: Recent studies have shown that astronauts experience altered immune response behavior during spaceflight, resulting in heightened susceptibility to illness. Resources and resupply shuttles will become scarcer with longer duration spaceflight, limiting ... ...

Abstract	Recent studies have shown that astronauts experience altered immune response behavior during spaceflight, resulting in heightened susceptibility to illness. Resources and resupply shuttles will become scarcer with longer duration spaceflight, limiting access to potentially necessary medical treatment and facilities. Thus, there is a need for preventative health countermeasures that can exploit in situ resource utilization technologies during spaceflight, such as additive manufacturing (i.e., 3D printing). The purpose of the current study was to test and validate recyclable antimicrobial materials compatible with additive manufacturing. Antimicrobial poly(lactic acid)- and polyurethane-based materials compatible with 3D printing were assessed for antimicrobial, mechanical, and chemical characteristics before and after one closed-loop recycling cycle. Our results show high biocidal efficacy (>90%) of both poly(lactic acid) and polyurethane materials while retaining efficacy post recycling, except for recycled-state polyurethane which dropped from 98.91% to 0% efficacy post 1-year accelerated aging. Significant differences in tensile and compression characteristics were observed post recycling, although no significant changes to functional chemical groups were found. Proof-of-concept medical devices developed show the potential for the on-demand manufacturing and recyclability of typically single-use medical devices using antimicrobial materials that could serve as preventative health countermeasures for immunocompromised populations, such as astronauts during spaceflight.
Language	English
Publishing date	2024-02-25
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2527146-5
ISSN	2073-4360 ; 2073-4360
ISSN (online)	2073-4360
ISSN	2073-4360
DOI	10.3390/polym16050626
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