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  1. Article: Women in cell science. Elisabetta Dejana. Interview by Fiona Watt.

    Dejana, Elisabetta

    Journal of cell science

    2005  Volume 118, Issue Pt 13, Page(s) 2789–2790

    MeSH term(s) Biological Science Disciplines/history ; Cell Physiological Phenomena ; Endothelium, Vascular/embryology ; Endothelium, Vascular/physiology ; Female ; Gender Identity ; History, 20th Century ; History, 21st Century ; Humans ; Italy ; Neovascularization, Physiologic/physiology ; Women, Working/history
    Language English
    Publishing date 2005-07-01
    Publishing country England
    Document type Biography ; Historical Article ; Interview
    ZDB-ID 2993-2
    ISSN 1477-9137 ; 0021-9533
    ISSN (online) 1477-9137
    ISSN 0021-9533
    DOI 10.1242/jcs.01722
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Expression of Concern: Expression of junctional adhesion molecule-A prevents spontaneous and random motility.

    Bazzoni, Gianfranco / Tonetti, Paolo / Manzi, Luca / Cera, Maria R / Balconi, Giovanna / Dejana, Elisabetta

    Journal of cell science

    2024  Volume 137, Issue 2

    Language English
    Publishing date 2024-01-30
    Publishing country England
    Document type Journal Article ; Expression of Concern
    ZDB-ID 2993-2
    ISSN 1477-9137 ; 0021-9533
    ISSN (online) 1477-9137
    ISSN 0021-9533
    DOI 10.1242/jcs.261904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Adhesion protein protocols

    Dejana, Elisabetta

    (Methods in molecular biology ; 96)

    1999  

    Author's details ed. by Elisabetta Dejana
    Series title Methods in molecular biology ; 96
    Collection
    Keywords Cell Adhesion Molecules ; Zell-Adhäsionsmolekül ; Proteine ; Methode ; Biochemische Methode
    Subject Eiweiss ; Protein ; CAM ; Cell adhesion molecule ; Zelladhäsionsmolekül ; Adhäsions-Molekül ; Methodik ; Verfahren ; Technik ; Methoden
    Language English
    Size XI, 229 S. : Ill., graph. Darst.
    Publisher Humana Press
    Publishing place Totowa, NJ
    Publishing country United States
    Document type Book
    HBZ-ID HT010409810
    ISBN 0-89603-417-8 ; 978-0-89603-417-4
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    1999 A 4193 order for loan Magazin

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  4. Article ; Online: Histological quantification of cerebral cavernous malformations in the murine brain.

    Maderna, Claudio / Dejana, Elisabetta / Malinverno, Matteo

    STAR protocols

    2022  Volume 3, Issue 2, Page(s) 101448

    Abstract: In the study of cerebral cavernous malformations (CCMs), the quantification of lesion burden is the main parameter for evaluation of disease severity and efficacy of drugs. We describe a reliable and cost-effective protocol to evaluate the number and the ...

    Abstract In the study of cerebral cavernous malformations (CCMs), the quantification of lesion burden is the main parameter for evaluation of disease severity and efficacy of drugs. We describe a reliable and cost-effective protocol to evaluate the number and the size of vascular malformations in the murine brain. This approach is based on histology and confocal imaging and can be performed with standard laboratory equipment. We detail the preparation of brain sections followed by image acquisition and analysis. For complete details on the use and execution of this protocol, please refer to Maderna et al. (2022).
    MeSH term(s) Animals ; Brain/diagnostic imaging ; Hemangioma, Cavernous, Central Nervous System/diagnostic imaging ; Histological Techniques ; Mice
    Language English
    Publishing date 2022-06-09
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2666-1667
    ISSN (online) 2666-1667
    DOI 10.1016/j.xpro.2022.101448
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The multifaceted

    Valentino, Mariaelena / Dejana, Elisabetta / Malinverno, Matteo

    Genes & diseases

    2020  Volume 8, Issue 6, Page(s) 798–813

    Abstract: The programmed cell death 10 ( ...

    Abstract The programmed cell death 10 (
    Language English
    Publishing date 2020-12-30
    Publishing country China
    Document type Journal Article ; Review
    ZDB-ID 2821806-1
    ISSN 2352-3042 ; 2352-3042
    ISSN (online) 2352-3042
    ISSN 2352-3042
    DOI 10.1016/j.gendis.2020.12.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Histological quantification of cerebral cavernous malformations in the murine brain

    Claudio Maderna / Elisabetta Dejana / Matteo Malinverno

    STAR Protocols, Vol 3, Iss 2, Pp 101448- (2022)

    2022  

    Abstract: Summary: In the study of cerebral cavernous malformations (CCMs), the quantification of lesion burden is the main parameter for evaluation of disease severity and efficacy of drugs. We describe a reliable and cost-effective protocol to evaluate the ... ...

    Abstract Summary: In the study of cerebral cavernous malformations (CCMs), the quantification of lesion burden is the main parameter for evaluation of disease severity and efficacy of drugs. We describe a reliable and cost-effective protocol to evaluate the number and the size of vascular malformations in the murine brain. This approach is based on histology and confocal imaging and can be performed with standard laboratory equipment. We detail the preparation of brain sections followed by image acquisition and analysis.For complete details on the use and execution of this protocol, please refer to Maderna et al. (2022). : Publisher’s note: Undertaking any experimental protocol requires adherence to local institutional guidelines for laboratory safety and ethics.
    Keywords Cell Biology ; Microscopy ; Model Organisms ; Neuroscience ; Stem Cells ; Science (General) ; Q1-390
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: A murine model of cerebral cavernous malformations with acute hemorrhage.

    Maderna, Claudio / Pisati, Federica / Tripodo, Claudio / Dejana, Elisabetta / Malinverno, Matteo

    iScience

    2022  Volume 25, Issue 3, Page(s) 103943

    Abstract: Cavernomas are multi-lumen and blood-filled vascular malformations which form in the brain and the spinal cord. They lead to hemorrhage, epileptic seizures, neurological deficits, and paresthesia. An effective medical treatment is still lacking, and the ... ...

    Abstract Cavernomas are multi-lumen and blood-filled vascular malformations which form in the brain and the spinal cord. They lead to hemorrhage, epileptic seizures, neurological deficits, and paresthesia. An effective medical treatment is still lacking, and the available murine models for cavernomas have several limitations for preclinical studies. These include disease phenotypes that differ from human diseases, such as restriction of the lesions to the cerebellum, and absence of acute hemorrhage. Additional limitations of current murine models include rapid development of lesions, which are lethal before the first month of age. Here, we have characterized a murine model that recapitulates features of the human disease: lesions develop after weaning throughout the entire CNS, including the spinal cord, and undergo acute hemorrhage. This provides a preclinical model to develop new drugs for treatment of acute hemorrhage in the brain and spinal cord, as an unmet medical emergency for patients with cavernomas.
    Language English
    Publishing date 2022-02-18
    Publishing country United States
    Document type Journal Article
    ISSN 2589-0042
    ISSN (online) 2589-0042
    DOI 10.1016/j.isci.2022.103943
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Endothelial cell transitions.

    Dejana, Elisabetta / Lampugnani, Maria Grazia

    Science (New York, N.Y.)

    2018  Volume 362, Issue 6416, Page(s) 746–747

    MeSH term(s) Blood Vessels/pathology ; Endothelial Cells/drug effects ; Endothelial Cells/physiology ; Epithelial-Mesenchymal Transition/drug effects ; Humans ; Vascular Diseases/drug therapy ; Vascular Diseases/pathology
    Language English
    Publishing date 2018-11-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.aas9432
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  9. Article ; Online: Resident Endothelial Progenitors Make Themselves at Home.

    Hirschi, Karen K / Dejana, Elisabetta

    Cell stem cell

    2018  Volume 23, Issue 2, Page(s) 153–155

    Abstract: Vascular endothelial cells adapt to their microenvironment and physiological demands to perform many essential functions. Recent studies (McDonald et al., 2018; Wakabayashi et al., 2018) suggest that quiescent endothelial stem/progenitor cells reside ... ...

    Abstract Vascular endothelial cells adapt to their microenvironment and physiological demands to perform many essential functions. Recent studies (McDonald et al., 2018; Wakabayashi et al., 2018) suggest that quiescent endothelial stem/progenitor cells reside within blood vessels and are activated in response to injury, suggesting they can be harnessed for therapeutic applications.
    MeSH term(s) Regeneration ; Stem Cells
    Language English
    Publishing date 2018-08-03
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2375354-7
    ISSN 1875-9777 ; 1934-5909
    ISSN (online) 1875-9777
    ISSN 1934-5909
    DOI 10.1016/j.stem.2018.07.014
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  10. Article ; Online: A murine model of cerebral cavernous malformations with acute hemorrhage

    Claudio Maderna / Federica Pisati / Claudio Tripodo / Elisabetta Dejana / Matteo Malinverno

    iScience, Vol 25, Iss 3, Pp 103943- (2022)

    2022  

    Abstract: Summary: Cavernomas are multi-lumen and blood-filled vascular malformations which form in the brain and the spinal cord. They lead to hemorrhage, epileptic seizures, neurological deficits, and paresthesia. An effective medical treatment is still lacking, ...

    Abstract Summary: Cavernomas are multi-lumen and blood-filled vascular malformations which form in the brain and the spinal cord. They lead to hemorrhage, epileptic seizures, neurological deficits, and paresthesia. An effective medical treatment is still lacking, and the available murine models for cavernomas have several limitations for preclinical studies. These include disease phenotypes that differ from human diseases, such as restriction of the lesions to the cerebellum, and absence of acute hemorrhage. Additional limitations of current murine models include rapid development of lesions, which are lethal before the first month of age. Here, we have characterized a murine model that recapitulates features of the human disease: lesions develop after weaning throughout the entire CNS, including the spinal cord, and undergo acute hemorrhage. This provides a preclinical model to develop new drugs for treatment of acute hemorrhage in the brain and spinal cord, as an unmet medical emergency for patients with cavernomas.
    Keywords Vascular remodeling ; Developmental neuroscience ; Model organism ; Science ; Q
    Subject code 610
    Language English
    Publishing date 2022-03-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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