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Article ; Online: Tocilizumab degradation via photo-catalytic ozonation process from aqueous.

Mehralipour, Jamal / Akbari, Hesam / Adibzadeh, Amir / Akbari, Hamed

2023 Volume 13, Issue 1, Page(s) 22402

Abstract: Following the advent of the coronavirus pandemic, tocilizumab has emerged as a potentially efficacious therapeutic intervention. The utilization of ... ...

Abstract	Following the advent of the coronavirus pandemic, tocilizumab has emerged as a potentially efficacious therapeutic intervention. The utilization of O
MeSH term(s)	Water Pollutants, Chemical/analysis ; Ozone/analysis ; Antibodies, Monoclonal, Humanized ; Organic Chemicals ; Oxidation-Reduction ; Catalysis
Chemical Substances	Water Pollutants, Chemical ; tocilizumab (I031V2H011) ; Ozone (66H7ZZK23N) ; Antibodies, Monoclonal, Humanized ; Organic Chemicals
Language	English
Publishing date	2023-12-16
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-49290-z
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Article: Nonionizing Electromagnetic Irradiations; Biological Interactions, Human Safety.

Akbari, Hamed / Taeb, Shahram / Adibzadeh, Amir / Akbari, Hesam

Journal of biomedical physics & engineering

2023 Volume 13, Issue 4, Page(s) 299–308

Abstract: Human is usually exposed to environmental radiation from natural and man-made sources. Therefore, it is important to investigate the effects of exposure to environmental radiation, partly related to understanding and protecting against the risk of ... ...

Abstract	Human is usually exposed to environmental radiation from natural and man-made sources. Therefore, it is important to investigate the effects of exposure to environmental radiation, partly related to understanding and protecting against the risk of exposure to environmental radiation with beneficial and adverse impacts on human life. The rapid development of technologies causes a dramatic enhancement of radiation in the human environment. In this study, we address the biological effects caused by different fractions of non-ionizing electromagnetic irradiation to humans and describe possible approaches for minimizing adverse health effects initiated by radiation. The main focus was on biological mechanisms initiated by irradiation and represented protection, and safety approaches to prevent health disorders.
Language	English
Publishing date	2023-08-01
Publishing country	Iran
Document type	Journal Article ; Review
ZDB-ID	2673599-4
ISSN	2251-7200
ISSN	2251-7200
DOI	10.31661/jbpe.v0i0.2010-1203
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Article ; Online: Visible-light-driven TiO

Ahmadmoazzam, Mehdi / Akbari, Hamed / Adibzadeh, Amir / Pourfadakari, Sudabeh / Akbari, Hesam

Environmental technology

2023 , Page(s) 1–12

Abstract: This study assessed wastewater treatment by visible-light/Peroxymonosulfate process using its linking with ... ...

Abstract	This study assessed wastewater treatment by visible-light/Peroxymonosulfate process using its linking with TiO
Language	English
Publishing date	2023-05-30
Publishing country	England
Document type	Journal Article
ISSN	1479-487X
ISSN (online)	1479-487X
DOI	10.1080/09593330.2023.2218042
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Article ; Online: Preparation and in vitro evaluation of protective effects of Silibinin-loaded polymeric micelles on human hair against UV-B radiation.

Zadeh, Behzad Sharif Makhmal / Akbari, Hamed / Salimi, Anayatollah

Journal of cosmetic dermatology

2024 Volume 23, Issue 5, Page(s) 1816–1827

Abstract: Background: The purpose of this study was to investigate the protective effect of Silibinin-loaded polymeric micelles from human hair against UV-B radiation.: Methods: Eight formulations with different concentrations of Silibinin, Pluronic F-127, and ...

Abstract	Background: The purpose of this study was to investigate the protective effect of Silibinin-loaded polymeric micelles from human hair against UV-B radiation. Methods: Eight formulations with different concentrations of Silibinin, Pluronic F-127, and Labrasol-Labrafil were made by a solvent evaporation method, and the selected formulation was chosen by examining their properties like particle size and loading efficiency. Six groups of human hair, including a group that received the selected formulation, were exposed to UV-B radiation and by calculating its factors such as peak-to-valley roughness, RMS roughness, FTIR, and the amount of protein loss, the protective effect of the selected formulation was judged. Results: According to the results, the loading efficiency and particle size of the selected formulation were 45.34% and 43.19 nm. The Silibinin release profile had two parts, fast and slow, which were suitable for creating a drug depot on hair. Its zeta potential also confirmed the minimum electrostatic interference between the formulation and hair surface. The zeta potential of selected formulation was -5.9 mv. Examination of AFM images showed that the selected formulation was able to prevent the increase in peak-to-valley roughness and RMS roughness caused by UV-B radiation. RMS roughness after 600 h of UV radiation in Groups 5 and 6 was significantly lower than the negative control group and the amount of this factor did not differ significantly between 0 and 600, so it can be concluded that the selected formulation containing Silibinin and the positive control group was able to prevent the increase of RMS roughness and hair destruction. In other hands, the two positive control groups and the selected formulation containing Silibinin were able to effectively reduce hair protein loss. Conclusion: Silibinin-loaded polymeric micelles were able to effectively protect hair from structural and chemical changes caused by UV-B radiation.
MeSH term(s)	Humans ; Ultraviolet Rays/adverse effects ; Silybin/pharmacology ; Silybin/administration & dosage ; Silybin/chemistry ; Micelles ; Hair/drug effects ; Hair/radiation effects ; Particle Size ; Silymarin/pharmacology ; Silymarin/administration & dosage ; Silymarin/chemistry ; Polymers/chemistry ; Drug Liberation/radiation effects ; Antioxidants/pharmacology ; Antioxidants/administration & dosage ; Drug Carriers/chemistry ; Drug Carriers/radiation effects
Chemical Substances	Silybin (4RKY41TBTF) ; Micelles ; Silymarin ; Polymers ; Antioxidants ; Drug Carriers
Language	English
Publishing date	2024-01-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2280551-5
ISSN	1473-2165 ; 1473-2130
ISSN (online)	1473-2165
ISSN	1473-2130
DOI	10.1111/jocd.16176
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Article ; Online: Tocilizumab degradation via photo-catalytic ozonation process from aqueous

Jamal Mehralipour / Hesam Akbari / Amir Adibzadeh / Hamed Akbari

Scientific Reports, Vol 13, Iss 1, Pp 1-

2023 Volume 21

Abstract: Abstract Following the advent of the coronavirus pandemic, tocilizumab has emerged as a potentially efficacious therapeutic intervention. The utilization of O3-Heterogeneous photocatalytic process (O3-HPCP) as a hybrid advanced oxidation technique has ... ...

Abstract	Abstract Following the advent of the coronavirus pandemic, tocilizumab has emerged as a potentially efficacious therapeutic intervention. The utilization of O3-Heterogeneous photocatalytic process (O3-HPCP) as a hybrid advanced oxidation technique has been employed for the degradation of pollutants. The present study employed a solvothermal technique for the synthesis of the BiOI-MOF composite. The utilization of FTIR, FESEM, EDAX, XRD, UV–vis, BET, TEM, and XPS analysis was employed to confirm the exceptional quality of the catalyst. the study employed an experimental design, subsequently followed by the analysis of collected data in order to forecast the most favorable conditions. The purpose of this study was to investigate the impact of several factors, including reaction time (30–60 min), catalyst dose (0.25–0.5 mg/L), pH levels (4–8), ozone concentration (20–40 mMol/L), and tocilizumab concentration (10–20 mg/L), on the performance of O3-HPCP. The best model was discovered by evaluating the F-value and P-value coefficients, which were found to be 0.0001 and 347.93, respectively. In the given experimental conditions, which include a catalyst dose of 0.46 mg/L, a reaction time of 59 min, a pH of 7.0, and an ozone concentration of 32 mMol/L, the removal efficiencies were found to be 92% for tocilizumab, 79.8% for COD, and 59% for TOC. The obtained R2 value of 0.98 suggests a strong correlation between the observed data and the predicted values, indicating that the reaction rate followed first-order kinetics. The coefficient of synergy for the degradation of tocilizumab was shown to be 1.22. The catalyst exhibited satisfactory outcomes, but with a marginal reduction in efficacy of approximately 3%. The sulfate ion (SO4 2−) exhibited no influence on process efficiency, whereas the nitrate ion (NO3 −) exerted the most significant impact among the anions. The progress of the process was impeded by organic scavengers, with methanol exhibiting the most pronounced influence and sodium azide exerting the least ...
Keywords	Medicine ; R ; Science ; Q
Subject code	660
Language	English
Publishing date	2023-12-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The Effect of Resistance Exercises Using an Elastic Band on Balance and Fear of Falling in Older Adults With Diabetic Peripheral Neuropathy: A 16-week Randomized Controlled Trial.

Armat, Mohammad Reza / Mortazavi, Hamed / Akbari, Hadi / Baghizade, Saeedeh

Archives of physical medicine and rehabilitation

2024 Volume 105, Issue 4, Page(s) 733–741

Abstract: Objective: The current study aimed to investigate the effect of resistance training using an elastic band on balance and fear of falling in older adults with diabetic peripheral neuropathy.: Design: The study was a clinical controlled trial with a ... ...

Abstract	Objective: The current study aimed to investigate the effect of resistance training using an elastic band on balance and fear of falling in older adults with diabetic peripheral neuropathy. Design: The study was a clinical controlled trial with a repeated measure design. Setting: Iranian Diabetes Foundation of Mashhad. Participants: The participants were 51 older adults with diabetic peripheral neuropathy and balance impairment (N=51). Interventions: Participants were randomly assigned to 2 groups; 1 group received balance training using an elastic band and the other group just received balance training. Main outcome measures: The main outcomes were balance and fear of falling that were measured using Berg Balance Scale and a short version of the Fall Efficiency Scale-International, respectively. Results: The results showed that balance resistance training with and without using an elastic band significantly enhances balance and reduces fear of falling in diabetic older adults suffering from balance issues. However, balance resistance training using an elastic band had a significantly better effect on the balance and fear of falling in the participants. The best results were obtained after week 12 (48 sessions of balance training). Conclusion: Balance rehabilitation programs may include an elastic band in balance resistance training for 12 weeks (3-4 sessions a week) for enhancing balance in diabetic older adults suffering from balance impairment.
MeSH term(s)	Humans ; Aged ; Resistance Training ; Diabetic Neuropathies ; Iran ; Postural Balance ; Fear ; Exercise Therapy ; Diabetes Mellitus
Language	English
Publishing date	2024-01-11
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	80057-0
ISSN	1532-821X ; 0003-9993
ISSN (online)	1532-821X
ISSN	0003-9993
DOI	10.1016/j.apmr.2023.11.017
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Article ; Online: Persulphate activation under UV radiation for cyclophosphamide degradation and mineralisation in aqueous solution

Akbari, Hamed / Adibzadeh, Amir

International Journal of Environmental Analytical Chemistry. 2022 Dec. 28, v. 102, no. 18 p.6752-6765

2022

Abstract: Hospital wastewater is mainly a source of pharmaceutical compounds entering water resources. The presence of the residual pharmaceutical compounds, due to the inability of the conventional treatment processes, will lead to the introduction of these ... ...

Abstract	Hospital wastewater is mainly a source of pharmaceutical compounds entering water resources. The presence of the residual pharmaceutical compounds, due to the inability of the conventional treatment processes, will lead to the introduction of these compounds into the environment and therefore will have its own environmental and health effects. In the present study, the degradation and mineralisation of cyclophosphamide from aqueous solution was investigated using the UV/Persulphate process and the effect of variables such as pH, persulphate concentration, reaction time, cyclophosphamide concentration, and mineralisation rate of cyclophosphamide were evaluated and compared with similar studies. The results of the study show that the pH of the process does not have much effect on the performance of the UV/Persulphate process and based on the results, the neutral pH was selected as the optimum pH. The concentration of 300 mg/L of persulphate was also obtained as the optimum concentration of persulphate. The kinetic analysis of decomposition also shows that the cyclophosphamide decomposition follows a pseudo-first-order kinetic model. Also, the study of the mineralisation rate of cyclophosphamide shows that the UV/Persulphate process can complete the mineralisation of 50 mg/L cyclophosphamide within 210 min. Finally, according to the results, it can be concluded that the UV/Persulphate process can be an effective and promising process for the degradation and mineralisation of cyclophosphamide.
Keywords	analytical chemistry ; aqueous solutions ; cyclophosphamide ; hospitals ; kinetics ; mineralization ; pH ; ultraviolet radiation ; wastewater ; Cytostatics ; emerging contaminant ; mineralisation ; sulphate radical
Language	English
Dates of publication	2022-1228
Size	p. 6752-6765.
Publishing place	Taylor & Francis
Document type	Article ; Online
ZDB-ID	120480-4
ISSN	1029-0397 ; 0306-7319 ; 0092-9085
ISSN (online)	1029-0397
ISSN	0306-7319 ; 0092-9085
DOI	10.1080/03067319.2020.1817423
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Article ; Online: Nothing's for Free

Kobra Bakhshizadeh Borj / Hamed Nasiri / Ali Akbari

International Journal of Digital Content Management, Vol 4, Iss 6, Pp 85-

Identifying the Most Important Content Monetization Mechanics in Mobile Games

2023 Volume 112

Abstract: Mobile games are getting a lot of attention as a content-based sector of the digital economy. Especially considering "Free with In-App Purchase" as the mainstream business model of these games, designing the right economic structure to monetize the ... ...

Abstract	Mobile games are getting a lot of attention as a content-based sector of the digital economy. Especially considering "Free with In-App Purchase" as the mainstream business model of these games, designing the right economic structure to monetize the content of mobile games is crucial. However, there is limited knowledge about the mechanisms of persuading users to pay for in-game content and most of the studies are merely focused on the revenue models. Due to this knowledge gap, this study attempts to aggregate the game monetization methods into a multi-level classification and focus on identifying the main content monetization mechanics of five genres: Arcade, Sport, Puzzle, Racing, and Platformer/ Runner. For this purpose, interviews were conducted by game design and economics experts about successful mobile games. As a result, a new multi-level classification for mobile games revenue models is proposed which includes monetization via selling core items, selling performance items, and providing supplementary services in addition to retailing and in-game advertising. It also became clear that monetization mechanics for each of these methods vary in different genres and change depending on the type of game. The results of this study can be useful for digital game researchers, designers, and marketeers to structure a better revenue stream.
Keywords	content monetization ; digital economy ; game design ; in-app purchase ; Bibliography. Library science. Information resources ; Z ; Communication. Mass media ; P87-96
Subject code	700
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Allameh Tabataba'i University Press
Document type	Article ; Online
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Article ; Online: Adsorption of diazinon from aqueous solution using metal organic framework and functionalized graphene: Comparison of BBD, ANN models.

Yousefi, Mahmood / Akbari, Hesam / Adibzadeh, Amir / Mohammadi, Ali Akbar / Baziar, Mansour / Abbasi Farajzadeh, Mohsen / Akbari, Hamed

Chemosphere

2024 Volume 351, Page(s) 141222

Abstract: In the present study, metal organic frameworks (MOFs) and aminated graphitic carbonaceous structure (ACS-RGO) through chemical synthesis prepared by a simple precipitation method and used for diazinon removal. Several techniques such as XRD , FESEM and ... ...

Abstract	In the present study, metal organic frameworks (MOFs) and aminated graphitic carbonaceous structure (ACS-RGO) through chemical synthesis prepared by a simple precipitation method and used for diazinon removal. Several techniques such as XRD , FESEM and FTIR were applied for identification of MOF-5 and ACS-RGO. Also, response surface methodology (RSM) was employed in this work to look at the effectiveness of diazinon adsorption. To forecast pesticide removal, we applied artificial neural network (ANN) and Box-Behnken Design (BBD) models. For the ANN model, a sensitivity analysis was also performed. The effect of independent variables like solution pH, various concentrations of diazinon, MOFs and ACS-RGO adsorbent dose and contact time were assessed to find out the optimum conditions. Based on the model prediction, the optimal condition for adsorption ACS-RGO and MOF-5 were determined to be pH 6.6 and 6.6, adsorbent dose of 0.59 and 0.906 g/L, and mixing time of 52.15 and 36.96 min respectively. These conditions resulted in 96.69% and 80.62% diazinon removal using ACS-RGO and MOF-5, respectively. Isotherm studies proved the adsorption of ACS-RGO and MOF-5 following the Langmuir isotherm model for diazinon removal. Diazinon removal followed by the pseudo-second and Pseudo-first order kinetics model provides a better fit for analyzing the kinetic data associated with pesticide adsorption for ACS-RGO and MOF-5, respectively. Based on the obtained results, the predicted values for the efficiency of diazinon removal with the ANN and BBD were similar (R
MeSH term(s)	Diazinon ; Graphite/chemistry ; Metal-Organic Frameworks ; Adsorption ; Neural Networks, Computer ; Pesticides ; Water Pollutants, Chemical/chemistry ; Kinetics
Chemical Substances	Diazinon (YUS1M1Q929) ; Graphite (7782-42-5) ; Metal-Organic Frameworks ; Pesticides ; Water Pollutants, Chemical
Language	English
Publishing date	2024-01-13
Publishing country	England
Document type	Journal Article
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2024.141222
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Article ; Online: Corrigendum to data on nitrate-nitrite pollution in the groundwater resources a Sonqor plain in Iran [Data in Brief Volume 20 (2018) Pages 394-401].

Jalili, Davoud / RadFard, Majid / Soleimani, Hamed / Nabavi, Samira / Akbari, Hesam / Akbari, Hamed / Kavosi, Ali / Abasnia, Abbas / Adibzadeh, Amir

Data in brief

2022 Volume 44, Page(s) 108529

Abstract: This corrects the article DOI: 10.1016/j.dib.2018.08.023.]. ...

Abstract	[This corrects the article DOI: 10.1016/j.dib.2018.08.023.].
Language	English
Publishing date	2022-08-05
Publishing country	Netherlands
Document type	Published Erratum
ZDB-ID	2786545-9
ISSN	2352-3409 ; 2352-3409
ISSN (online)	2352-3409
ISSN	2352-3409
DOI	10.1016/j.dib.2022.108529
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