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  1. Article ; Online: Neuroimmune signaling in neuropsychiatric disease.

    Morrow, A Leslie / Price, Lawrence H

    Psychopharmacology

    2019  Volume 236, Issue 10, Page(s) 2855

    Language English
    Publishing date 2019-10-21
    Publishing country Germany
    Document type Editorial
    ZDB-ID 130601-7
    ISSN 1432-2072 ; 0033-3158
    ISSN (online) 1432-2072
    ISSN 0033-3158
    DOI 10.1007/s00213-019-05355-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Outcomes of a Nurse-Led Difficult Urinary Catheter Team in an Academic Medical Center.

    Price, David / McKeon, Leslie

    Journal of nursing care quality

    2020  Volume 35, Issue 4, Page(s) 309–316

    Abstract: Background: Catheter insertion for complex patients by inexperienced nurses can lead to avoidable iatrogenic urethral injury and catheter-associated urinary tract infection (CAUTI).: Purpose: The study aim was to evaluate a comprehensive nurse-led ... ...

    Abstract Background: Catheter insertion for complex patients by inexperienced nurses can lead to avoidable iatrogenic urethral injury and catheter-associated urinary tract infection (CAUTI).
    Purpose: The study aim was to evaluate a comprehensive nurse-led difficult urinary catheterization (DUC) Program to reduce patient CAUTIs.
    Methods: A retrospective cohort study design was used to evaluate the DUC Program's effectiveness during 2013 to 2017. Measures included RN DUC consultations, protocol adherence, patient CAUTIs, and urology consults.
    Results: The RN DUC team consulted 435 patients with a 92% insertion success rate. The DUC protocol adherence was 66.1%. Patient CAUTIs decreased from baseline (169) to year 4 (24) (odds ratio: 0.1889, 95% confidence interval = 0.1231-0.2898, P < .001). Urology consults decreased from baseline (40) to year 3 (21), however, increased in year 4 (80) when a urology residency program was started.
    Conclusion: This comprehensive program was effective in improving catheter insertion technique, eliminating urology consults, and reducing CAUTIs when combined with organizational prevention measures.
    MeSH term(s) Academic Medical Centers ; Catheter-Related Infections/prevention & control ; Female ; Humans ; Iatrogenic Disease/prevention & control ; Male ; Middle Aged ; Nursing Staff, Hospital/education ; Retrospective Studies ; Urinary Catheterization/nursing ; Urinary Tract Infections/prevention & control
    Language English
    Publishing date 2020-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1089089-0
    ISSN 1550-5065 ; 1057-3631
    ISSN (online) 1550-5065
    ISSN 1057-3631
    DOI 10.1097/NCQ.0000000000000464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: An Integrative Data Analysis of Main and Moderated Crossover Effects of Parent-Mediated Interventions on Depression and Anxiety Symptoms in Youth in Foster Care.

    Tiberio, Stacey S / Pears, Katherine C / Buchanan, Rohanna / Chamberlain, Patricia / Leve, Leslie D / Price, Joseph M / Hussong, Andrea M

    Prevention science : the official journal of the Society for Prevention Research

    2023  Volume 24, Issue 8, Page(s) 1547–1557

    Abstract: Without preventative intervention, youth with a history of foster care (FC) involvement have a high likelihood of developing depression and anxiety (DA) symptoms. The current study used integrative data analysis to harmonize data across four foster and ... ...

    Abstract Without preventative intervention, youth with a history of foster care (FC) involvement have a high likelihood of developing depression and anxiety (DA) symptoms. The current study used integrative data analysis to harmonize data across four foster and kinship parent-mediated interventions (and seven randomized control trials) designed to reduce youth externalizing and other problem behaviors to determine if, and for how long, these interventions may have crossover effects on youth DA symptoms. Moderation of intervention effects by youth biological sex, developmental period, number of prior placements, and race/ethnicity was also examined. Youth (N = 1891; 59% female; ages 4 to 18 years) behaviors were assessed via the Child Behavior Checklist, Parent Daily Report, and Eyberg Child Behavior Inventory at baseline, the end of the interventions (4-6 months post baseline), and two follow-up assessments (9-12 months and 18-24 months post baseline), yielding 4830 total youth-by-time assessments. The interventions were effective at reducing DA symptoms at the end of the interventions; however, effects were only sustained for one program at the follow-up assessments. No moderation effects were found. The current study indicates that parent-mediated interventions implemented during childhood or adolescence aimed at reducing externalizing and other problem behaviors had crossover effects on youth DA symptoms at the end of the interventions. Such intervention effects were sustained 12 and 24 months later only for the most at-risk youth involved in the most intensive intervention.
    MeSH term(s) Child ; Humans ; Female ; Adolescent ; Male ; Depression/prevention & control ; Anxiety/prevention & control ; Parents ; Foster Home Care ; Data Analysis
    Language English
    Publishing date 2023-03-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2251270-6
    ISSN 1573-6695 ; 1389-4986
    ISSN (online) 1573-6695
    ISSN 1389-4986
    DOI 10.1007/s11121-023-01524-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A qualitative exploration of Indigenous patients' experiences of racism and perspectives on improving cultural safety within health care.

    Pilarinos, Andreas / Field, Shannon / Vasarhelyi, Krisztina / Hall, David / Fox, Elder Doris / Price, Elder Roberta / Bonshor, Leslie / Bingham, Brittany

    CMAJ open

    2023  Volume 11, Issue 3, Page(s) E404–E410

    Abstract: Background: In Canada, Indigenous Peoples continue to experience persistent health inequities, resulting in disproportionately poorer health outcomes compared with non-Indigenous Canadians. This study engaged Indigenous patients accessing health care in ...

    Abstract Background: In Canada, Indigenous Peoples continue to experience persistent health inequities, resulting in disproportionately poorer health outcomes compared with non-Indigenous Canadians. This study engaged Indigenous patients accessing health care in Vancouver, Canada, about their experiences of racism and improving cultural safety within health care.
    Methods: A research team consisting of Indigenous and non-Indigenous researchers committed to employing a Two-Eyed Seeing approach and conducting culturally safe research hosted 2 sharing circles in May 2019 with Indigenous people recruited from urban health care settings. Talking circles were led by Indigenous Elders, and thematic analysis was used to identify overarching themes.
    Results: A total of 26 participants attended 2 sharing circles, which included 25 self-identifying women and 1 self-identifying man. Thematic analysis resulted in the identification of 2 major themes: negative experiences in health care and perspectives on promising health care practices. For the first major theme, subthemes included the following: experiences of racism lead to poorer care experiences and health outcomes, Indigenous-specific racism results in mistrust in the health care system, and participants experience discrediting of traditional medicine and Indigenous perspectives on health. For the second major theme, subthemes included the following: Indigenous-specific services and supports improve trust in health care, Indigenous cultural safety education is necessary for all health care-involved staff, and providing welcoming, Indigenized spaces for Indigenous patients encourages health care engagement.
    Interpretation: Despite participants' racist health care experiences, receiving culturally safe care was credited with improving trust in the health care system and well-being. The continued expansion of Indigenous cultural safety education, the creation of welcoming spaces, recruitment of Indigenous staff, and Indigenous self-determination over health care services can improve Indigenous patients' health care experiences.
    MeSH term(s) Male ; Humans ; Female ; Aged ; Racism ; Canada/epidemiology ; Indigenous Peoples ; Research Personnel ; Delivery of Health Care
    Language English
    Publishing date 2023-05-02
    Publishing country Canada
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2701622-5
    ISSN 2291-0026 ; 2291-0026
    ISSN (online) 2291-0026
    ISSN 2291-0026
    DOI 10.9778/cmajo.20220135
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Bacterial culture and antimicrobial susceptibility results from bovine milk samples submitted to four veterinary diagnostic laboratories in Australia from 2015 to 2019.

    Langhorne, Charlotte / Gupta, Suman Das / Horsman, Sara / Wood, Caitlin / Wood, Benjamin J / Barker, Leslie / Deutscher, Ania / Price, Rochelle / McGowan, Michael R / Humphris, Mark / Ranjbar, Shahab / Henning, Joerg / Gibson, Justine S

    Frontiers in veterinary science

    2023  Volume 10, Page(s) 1232048

    Abstract: A 5-year retrospective study was conducted to describe the mastitis-causing organisms isolated from bovine milk samples submitted to four veterinary diagnostic laboratories in Australia. The aim of this study was to identify temporal, geographical, and ... ...

    Abstract A 5-year retrospective study was conducted to describe the mastitis-causing organisms isolated from bovine milk samples submitted to four veterinary diagnostic laboratories in Australia. The aim of this study was to identify temporal, geographical, and seasonal patterns of occurrence for the organisms and report the
    Language English
    Publishing date 2023-08-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2023.1232048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Proceedings from the 2022 Consensus Conference to Implement Optimal Venous Thromboembolism Prophylaxis in Trauma.

    Haut, Elliott R / Byrne, James P / Price, Michelle A / Bixby, Pamela / Bulger, Eileen M / Lake, Leslie / Costantini, Todd

    The journal of trauma and acute care surgery

    2022  Volume 94, Issue 3, Page(s) 461–468

    Abstract: Abstract: On May 4 and 5, 2022, a meeting of multidisciplinary stakeholders in the prevention and treatment of venous thromboembolism (VTE) after trauma was convened by the Coalition for National Trauma Research, funded by the National Heart, Lung, and ... ...

    Abstract Abstract: On May 4 and 5, 2022, a meeting of multidisciplinary stakeholders in the prevention and treatment of venous thromboembolism (VTE) after trauma was convened by the Coalition for National Trauma Research, funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health, and hosted by the American College of Surgeons in Chicago, Illinois. This consensus conference gathered more than 40 in-person and 80 virtual attendees, including trauma surgeons, other physicians, thrombosis experts, nurses, pharmacists, researchers, and patient advocates. The objectives of the meeting were twofold: (1) to review and summarize the present state of the scientific evidence regarding VTE prevention strategies in injured patients and (2) to develop consensus on future priorities in VTE prevention implementation and research gaps.To achieve these objectives, the first part of the conference consisted of talks from physician leaders, researchers, clinical champions, and patient advocates to summarize the current state of knowledge of VTE pathogenesis and prevention in patients with major injury. Video recordings of all talks and accompanying slides are freely available on the conference website ( https://www.nattrauma.org/research/research-policies-templates-guidelines/vte-conference/ ). Following this curriculum, the second part of the conference consisted of a series of small-group breakout sessions on topics potentially requiring future study. Through this process, research priorities were identified, and plans of action to develop and undertake future studies were defined.The 2022 Consensus Conference to Implement Optimal VTE Prophylaxis in Trauma answered the National Trauma Research Action Plan call to define a course for future research into preventing thromboembolism after trauma. A multidisciplinary group of clinical champions, physicians, scientists, and patients delineated clear objectives for future investigation to address important, persistent key knowledge gaps. The series of papers from the conference outlines the consensus based on the current literature and a roadmap for research to answer these unanswered questions.
    MeSH term(s) Humans ; Anticoagulants ; Chicago ; Physicians ; Thrombosis ; Venous Thromboembolism/etiology
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2022-12-19
    Publishing country United States
    Document type Congress ; Research Support, N.I.H., Extramural
    ZDB-ID 2651070-4
    ISSN 2163-0763 ; 2163-0755
    ISSN (online) 2163-0763
    ISSN 2163-0755
    DOI 10.1097/TA.0000000000003843
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: Dutch Society

    Price, John Leslie

    1588-1713

    2014  

    Abstract: This fascinating new interpretation of Dutch society in the Golden Age is a major contribution to early modern history. Dutch society in this period was to a significant extent different from that of the rest of Europe. A high proportion of the ... ...

    Abstract This fascinating new interpretation of Dutch society in the Golden Age is a major contribution to early modern history. Dutch society in this period was to a significant extent different from that of the rest of Europe. A high proportion of the population lived in the numerous towns and market forces had penetrated the whole economy and transformed every level of society. The heart of this book is a discussion of the processes by which this unique society was produced and an analysis of its character. These social changes are set against the late sixteenth century background and in the context
    Language English
    Size Online-Ressource (488 p)
    Publisher Taylor and Francis
    Publishing place Hoboken
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9780582264267 ; 058226426X
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Article ; Online: Pediatric Ovarian Torsion: Should You Go With the Flow?

    Sims, Morgan J / Price, Amanda B / Hirsig, Leslie E / Collins, Heather R / Hill, Jeanne G / Titus, M Olivia

    Pediatric emergency care

    2022  Volume 38, Issue 6, Page(s) e1332–e1335

    Abstract: Objectives: Ovarian torsion (OT) is an emergency that mandates early detection and surgical detorsion to avoid catastrophic consequences of further adnexal injury. Prompt ultrasound is critical for accurate diagnosis. Traditionally, evaluation of ... ...

    Abstract Objectives: Ovarian torsion (OT) is an emergency that mandates early detection and surgical detorsion to avoid catastrophic consequences of further adnexal injury. Prompt ultrasound is critical for accurate diagnosis. Traditionally, evaluation of arterial and venous flow was used as a diagnostic tool for OT, but recent radiologic research has indicated that ovarian size and size discrepancy between sides is a better diagnostic criterion. This study seeks to determine whether ovarian size discrepancy or vascular flow to the ovary is more accurate in the diagnosis of OT in the pediatric emergency population and to better describe symptoms that distinguish OT from other abdominal and pelvic pathology.
    Methods: This was a retrospective, cross-sectional study evaluating all female pediatric patients, aged 1 to 18 years, who underwent a pelvic ultrasound to evaluate for OT over a 2-year period in our pediatric emergency department. Patients suitable for inclusion were identified via Nuance mPowerTM, a search engine that provides clinical analytics based on radiology reports generated within our institution.
    Results: We reviewed the medical records of 193 female patients aged 1 to 18 years, all of whom had a pelvic ultrasound (with or without Doppler) to evaluate for OT during the study period. In comparing ovarian size on ultrasound, patients with OT had a significantly larger magnitude of difference in ovarian volume than patients without torsion (5.57× [interquartile range, 3-12.5] vs 1.56× [interquartile range, 1.24-2.25; P < 0.001]). Ovarian torsion was associated with a 33-fold increased risk of lack of arterial flow (relative risk, 33.33) and with a 9-fold increased risk of lack of venous flow (relative risk, 9.27), when compared with those patients without OT. Patients with OT were significantly more likely to have emesis and peritoneal signs on examination, as well as previous history of OT (P = 0.01, 0.02, and 0.002, respectively) than those without OT. All patients with OT reported abdominal pain.
    Conclusions: We found that a large size discrepancy between ovaries is indicative of OT. Our data also suggest that presence of Doppler flow on ultrasound cannot be used to exclude OT but that lack of Doppler flow on ultrasound is a significant diagnostic marker. As previous studies have also found, clinical symptoms of OT are nonspecific and do not offer any certainty in differentiating OT from other pathologies.
    MeSH term(s) Child ; Cross-Sectional Studies ; Female ; Humans ; Ovarian Diseases/diagnostic imaging ; Ovarian Torsion/diagnostic imaging ; Retrospective Studies ; Torsion Abnormality/diagnostic imaging ; Torsion Abnormality/surgery
    Language English
    Publishing date 2022-02-28
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 632588-9
    ISSN 1535-1815 ; 0749-5161
    ISSN (online) 1535-1815
    ISSN 0749-5161
    DOI 10.1097/PEC.0000000000002679
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Activity spaces: assessing differences in alcohol exposures and alcohol use for parents

    Freisthler, Bridget / Kepple, Nancy J / Wolf, Jennifer Price / Carson, Leslie

    GeoJournal. 2021 Feb., v. 86, no. 1

    2021  

    Abstract: Parental alcohol use and alcohol outlet densities in residential areas are related to risk for child maltreatment. However, some parents spend significant time outside of their residential neighborhood. Thus, we may not be accurately assessing how ... ...

    Abstract Parental alcohol use and alcohol outlet densities in residential areas are related to risk for child maltreatment. However, some parents spend significant time outside of their residential neighborhood. Thus, we may not be accurately assessing how alcohol environments are related to risks for problematic parenting. Here, we examine how residential environments and activity spaces are related to outlet density and whether drinking events in our sample of parents differ by location (e.g., routine vs. rare locations) and whether their children are present. We conducted semi-structured interviews with 60 parents living in four cities in the San Francisco Bay area who provided information on where they spent time, where they drank, and whether children were present. We constructed measures of activity spaces (e.g., convex hull polygons) and activity patterns (e.g., shortest network distance) and calculated outlet density in each. Density of alcohol outlets for residential Census tract was not related to density of the activity space and activity pattern measures. Alcohol use occurred more frequently (regardless of whether their children were present) inside activity spaces operationalized as convex hull polygons or two standard deviational ellipses. Measures that capture larger activity space areas (e.g., convex hull polygons, two standard deviational ellipses) may better model where people spend time, regardless of whether the location is routine or rare. By continuing to use activity spaces to explore relationships between outlet densities, drinking behaviors, and problems, we can start to ascertain those mechanisms by which outlets may affect local problems.
    Keywords alcohols ; child abuse ; people ; residential areas
    Language English
    Dates of publication 2021-02
    Size p. 69-79.
    Publishing place Springer Netherlands
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 715360-0
    ISSN 1572-9893 ; 0343-2521
    ISSN (online) 1572-9893
    ISSN 0343-2521
    DOI 10.1007/s10708-019-10059-5
    Database NAL-Catalogue (AGRICOLA)

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  10. Article: Safety and efficacy of primaquine in patients with

    Verma, Reena / Commons, Robert J / Gupta, Apoorv / Rahi, Manju / Nitika / Bharti, Praveen K / Thriemer, Kamala / Rajasekhar, Megha / Singh-Phulgenda, Sauman / Adhikari, Bipin / Alam, Mohammad Shafiul / Ghimire, Prakash / Khan, Wasif A / Kumar, Rishikesh / Leslie, Toby / Ley, Benedikt / Llanos-Cuentas, Alejandro / Pukrittayakamee, Sasithon / Rijal, Komal Raj /
    Rowland, Mark / Saravu, Kavitha / Simpson, Julie A / Guerin, Philippe J / Price, Ric N / Sharma, Amit

    BMJ global health

    2023  Volume 8, Issue 12

    Abstract: Background: The optimal dosing of primaquine to prevent relapsing : Methods: A systematic review identified : Results: In 791 patients from 7 studies in the one-stage meta-analysis, the day 180 cumulative risk of recurrence was 61.1% (95% CI 42.2% ...

    Abstract Background: The optimal dosing of primaquine to prevent relapsing
    Methods: A systematic review identified
    Results: In 791 patients from 7 studies in the one-stage meta-analysis, the day 180 cumulative risk of recurrence was 61.1% (95% CI 42.2% to 80.4%; 201 patients; 25 recurrences) after treatment without primaquine, 28.8% (95% CI 8.2% to 74.1%; 398 patients; 4 recurrences) following low total (2 to <5 mg/kg) and 0% (96 patients; 0 recurrences) following high total dose primaquine (≥5 mg/kg). In the subsequent two-stage meta-analysis of nine studies (3529 patients), the pooled proportions of
    Conclusions: Primaquine treatment led to a marked decrease in
    Prospero registration number: CRD42022313730.
    MeSH term(s) Humans ; Primaquine/therapeutic use ; Primaquine/adverse effects ; Malaria, Vivax/drug therapy ; Malaria, Vivax/chemically induced ; Malaria, Vivax/prevention & control ; Antimalarials/adverse effects ; Plasmodium vivax ; Recurrence ; Asia, Southern ; Hemoglobins/therapeutic use
    Chemical Substances Primaquine (MVR3634GX1) ; Antimalarials ; Hemoglobins
    Language English
    Publishing date 2023-12-20
    Publishing country England
    Document type Systematic Review ; Meta-Analysis ; Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2059-7908
    ISSN 2059-7908
    DOI 10.1136/bmjgh-2023-012675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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