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Article: The changing landscape of infective endocarditis in the Netherlands.

Kietselaer, B L J H

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

2015 Volume 23, Issue 11, Page(s) 546–547

Language	English
Publishing date	2015-09-22
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2211468-3
ISSN	1876-6250 ; 1568-5888 ; 0929-7456
ISSN (online)	1876-6250
ISSN	1568-5888 ; 0929-7456
DOI	10.1007/s12471-015-0752-z
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Article: Echocardiographic estimation of pulmonary hypertension in COVID-19 patients.

Wolters, A E P / Wolters, A J P / van Kraaij, T D A / Kietselaer, B L J H

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

2022 Volume 30, Issue 11, Page(s) 510–518

Abstract: Introduction: Coronavirus disease 2019 (COVID-19) is the cause of a devastating global pandemic and is not likely to be fully resolved in the near future. In most cases COVID-19 presents with mild symptoms, but in a minority of patients respiratory and ... ...

Abstract	Introduction: Coronavirus disease 2019 (COVID-19) is the cause of a devastating global pandemic and is not likely to be fully resolved in the near future. In most cases COVID-19 presents with mild symptoms, but in a minority of patients respiratory and multi-organ failure may ensue. Previous research has focused on the correlation between COVID-19 and a variety of cardiovascular complications. However, the effect of COVID-19 on pulmonary hypertension (PH) and correlated cardiovascular parameters has not been evaluated extensively. Methods: This study was designed as a single-centre, semi-quantitative analysis. PH was considered to be present if echocardiographic measurements estimated right ventricular systolic pressure at rest to be 36 mm Hg or higher in combination with indirect indicators of right ventricular overload. Results: In total, 101 patients (67.3% male) were included in this study, with a mean age of 66 years (range 23-98 years). PH was diagnosed by echocardiographic estimation in 30 patients (29.7%). Echocardiographically estimated PH (eePH) was not correlated with a diagnosis of heart failure or pulmonary embolism. Mortality was significantly higher among COVID-19 patients with eePH (p = 0.015). In all 10 of 20 surviving eePH patients in whom echocardiographic follow-up was obtained, echocardiographic estimations of pulmonary pressures showed a significant decrease after a median of 144 ± 72 days. Conclusion: eePH is frequently observed in COVID-19 patients and is correlated with increased mortality. COVID-19-related eePH appears to be reversible after recovery. Vigilant attention and a low threshold for performance of echocardiography in COVID-19 patients seems warranted, as eePH may be applicable as a prognostic risk factor.
Language	English
Publishing date	2022-06-30
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2211468-3
ISSN	1876-6250 ; 1568-5888 ; 0929-7456
ISSN (online)	1876-6250
ISSN	1568-5888 ; 0929-7456
DOI	10.1007/s12471-022-01702-x
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Article: Coronary anomaly: when you think you've seen it all.

Holvoet, W / Mihl, C / Ruiters, A W / Kietselaer, B L J H / Bekkers, S C A M

Acta cardiologica

2018 Volume 74, Issue 1, Page(s) 86–87

MeSH term(s)	Aged ; Computed Tomography Angiography/methods ; Coronary Angiography/methods ; Coronary Vessel Anomalies/diagnosis ; Coronary Vessels/diagnostic imaging ; Humans ; Imaging, Three-Dimensional ; Male
Language	English
Publishing date	2018-01-16
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	390197-x
ISSN	0001-5385
ISSN	0001-5385
DOI	10.1080/00015385.2018.1428160
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Article ; Online: Editorial to: Baseline MDCT findings after prosthetic heart valve implantation provide important complementary information to echocardiography for follow-up purposes by Suchá et al.

Peeters, F E C M / Kietselaer, B L J H

European radiology

2015 Volume 26, Issue 4, Page(s) 1007–1008

Abstract: Over the last years a growing number of prosthetic heart valve (PHV) implantation procedures have been performed in sequence with the aging of the population and improving surgical techniques. Currently, echocardiography is the most important tool in the ...

Abstract	Over the last years a growing number of prosthetic heart valve (PHV) implantation procedures have been performed in sequence with the aging of the population and improving surgical techniques. Currently, echocardiography is the most important tool in the follow-up and evaluation of complications associated with the PHV (pannus, thrombus, endocarditis). However, echocardiographic examination of PHV associated disease may be hampered by poor acoustic window or scatter artefacts caused by the PHV. PHV related disease such as endocarditis is related with a poor prognosis, especially when complications such as periannular abcess formation occurs. Early treatment of PHV associated disease improves prognosis. Therefore, an unmet clinical need for early detection of complications exists. In the evaluation of PHV (dys)function, multidetector-row computed tomography (MDCT) has shown to be of additive value. A necessity for MDCT to be implemented in daily practice is to be able to distinguish between normal and pathological features. Key Points • Early detection of PHV related complications improves prognosis • MDCT has additive value to echocardiography in the evaluation of PHV • RCTs for MDCT evaluation of PHV are required for clinical implementation.
MeSH term(s)	Aortic Valve/surgery ; Echocardiography ; Follow-Up Studies ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation ; Heart Valves/diagnostic imaging ; Humans ; Radiography
Language	English
Publishing date	2015-10-16
Publishing country	Germany
Document type	Editorial ; Comment
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-015-3937-3
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Article ; Online: Geometric characteristics of bicuspid aortic valves.

Nijs, Jan / Vangelder, Babs / Tanaka, Kaoru / Gelsomino, Sandro / Van Loo, Ines / La Meir, Mark / Maessen, Jos / Kietselaer, Bas L J H

JTCVS techniques

2021 Volume 10, Page(s) 200–215

Abstract: Objective: We studied the coaptation angles α and β in bicuspid aortic valve geometry from computed tomography scan images.: Methods: In 45 patients, we calculated the coaptation angle α (the angle between the nonfused commissures crossing the center ...

Abstract	Objective: We studied the coaptation angles α and β in bicuspid aortic valve geometry from computed tomography scan images. Methods: In 45 patients, we calculated the coaptation angle α (the angle between the nonfused commissures crossing the center of coaptation), angle β (between the nonfused commissures crossing the center of the reference circle), angles γ Results: The coaptation angles α and β were significantly different ( Conclusions: The coaptation angle α is influenced by the length of the raphe, whereas angle β is dependent on the position of the commissures. The position of the raphe can vary and is not always situated in the middle of the free edge. The position of the right/non commissure is variable, whereas the right/left commissure is more fixed.
Language	English
Publishing date	2021-08-27
Publishing country	United States
Document type	Journal Article
ISSN	2666-2507
ISSN (online)	2666-2507
DOI	10.1016/j.xjtc.2021.08.032
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Article ; Online: Pericardial fat and its influence on cardiac diastolic function.

de Wit-Verheggen, Vera H W / Altintas, Sibel / Spee, Romy J M / Mihl, Casper / van Kuijk, Sander M J / Wildberger, Joachim E / Schrauwen-Hinderling, Vera B / Kietselaer, Bas L J H / van de Weijer, Tineke

Cardiovascular diabetology

2020 Volume 19, Issue 1, Page(s) 129

Abstract: Background: Pericardial fat (PF) has been suggested to directly act on cardiomyocytes, leading to diastolic dysfunction. The aim of this study was to investigate whether a higher PF volume is associated with a lower diastolic function in healthy ... ...

Abstract	Background: Pericardial fat (PF) has been suggested to directly act on cardiomyocytes, leading to diastolic dysfunction. The aim of this study was to investigate whether a higher PF volume is associated with a lower diastolic function in healthy subjects. Methods: 254 adults (40-70 years, BMI 18-35 kg/m Results: Significant associations for all four diastolic parameters with the PF volume were found after adjusting for BMI, age, and sex. In addition, subjects with high pericardial fat had a reduced left atrial volume index (p = 0.02), lower E/e (p < 0.01) and E/A (p = 0.01), reduced e' lateral (p < 0.01), reduced e' septal p = 0.03), compared to subjects with low pericardial fat. Conclusion: These findings confirm that pericardial fat volume, even in healthy subjects with normal cardiac function, is associated with diastolic function. Our results suggest that the mechanical effects of PF may limit the distensibility of the heart and thereby directly contribute to diastolic dysfunction. Trial registration NCT01671930.
MeSH term(s)	Adipose Tissue/diagnostic imaging ; Adipose Tissue/physiopathology ; Adiposity ; Adult ; Aged ; Asymptomatic Diseases ; Computed Tomography Angiography ; Coronary Angiography ; Cross-Sectional Studies ; Diastole ; Echocardiography ; Female ; Humans ; Male ; Middle Aged ; Pericardium ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Ventricular Dysfunction, Left/diagnostic imaging ; Ventricular Dysfunction, Left/etiology ; Ventricular Dysfunction, Left/physiopathology ; Ventricular Function, Left
Language	English
Publishing date	2020-08-17
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1475-2840
ISSN (online)	1475-2840
DOI	10.1186/s12933-020-01097-2
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Article ; Online: Unilateral left-sided thoracoscopic ablation of atrial fibrillation concomitant to minimally invasive bypass grafting of the left anterior descending artery.

van der Heijden, Claudia A J / Segers, Patrique / Masud, Anna / Weberndörfer, Vanessa / Chaldoupi, Sevasti-Marisevi / Luermans, Justin G L M / Bijvoet, Geertruida P / Kietselaer, Bas L J H / van Kuijk, Sander M J / Barenbrug, Paul J C / Maessen, Jos G / Bidar, Elham / Maesen, Bart

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

2022 Volume 62, Issue 5

Abstract: Objectives: Thoracoscopic ablation for atrial fibrillation (AF) and minimally invasive direct coronary artery bypass (MIDCAB) with robot-assisted left internal mammary artery (LIMA) harvesting may represent a safe and effective alternative to more ... ...

Abstract	Objectives: Thoracoscopic ablation for atrial fibrillation (AF) and minimally invasive direct coronary artery bypass (MIDCAB) with robot-assisted left internal mammary artery (LIMA) harvesting may represent a safe and effective alternative to more invasive surgical approaches via sternotomy. The aim of our study was to describe the feasibility, safety and efficacy of a unilateral left-sided thoracoscopic AF ablation and concomitant MIDCAB surgery. Methods: Retrospective analysis of a prospectively gathered cohort was performed of all consecutive patients with AF and at least a critical left anterior descending artery (LAD) stenosis that underwent unilateral left-sided thoracoscopic AF ablation and concomitant off-pump MIDCAB surgery in the Maastricht University Medical Centre between 2017 and 2021. Results: Twenty-three patients were included [age 69 years (standard deviation = 8), paroxysmal AF 61%, left atrial volume index 42 ml/m2 (standard deviation = 11)]. Unilateral left-sided thoracoscopic isolation of the left (n = 23) and right (n = 22) pulmonary veins and box (n = 21) by radiofrequency ablation was succeeded by epicardial validation of exit- and entrance block (n = 22). All patients received robot-assisted LIMA harvesting and off-pump LIMA-LAD anastomosis through a left mini-thoracotomy. The perioperative complications consisted of one bleeding of the thoracotomy wound and one aborted myocardial infarction not requiring intervention. The mean duration of hospital stay was 6 days (standard deviation = 2). After discharge, cardiac hospital readmission occurred in 4 patients (AF n = 1; pleural- and pericardial effusion n = 2, myocardial infarction requiring the percutaneous intervention of the LIMA-LAD n = 1) within 1 year. After 12 months, 17/21 (81%) patients were in sinus rhythm when allowing anti-arrhythmic drugs. Finally, the left atrial ejection fraction improved postoperatively [26% (standard deviation = 11) to 38% (standard deviation = 7), P = 0.01]. Conclusions: In this initial feasibility and early safety study, unilateral left-sided thoracoscopic AF ablation and concomitant MIDCAB for LIMA-LAD grafting is a feasible, safe and efficacious for patients with AF and a critical LAD stenosis.
MeSH term(s)	Aged ; Anti-Arrhythmia Agents ; Arteries ; Atrial Fibrillation/surgery ; Constriction, Pathologic ; Coronary Stenosis ; Humans ; Minimally Invasive Surgical Procedures ; Myocardial Infarction ; Retrospective Studies ; Treatment Outcome
Chemical Substances	Anti-Arrhythmia Agents
Language	English
Publishing date	2022-08-10
Publishing country	Germany
Document type	Journal Article
ZDB-ID	639293-3
ISSN	1873-734X ; 1010-7940 ; 1567-4258
ISSN (online)	1873-734X
ISSN	1010-7940 ; 1567-4258
DOI	10.1093/ejcts/ezac409
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Article ; Online: Prevalence, pathophysiology, prediction and health-related quality of life of long COVID: study protocol of the longitudinal multiple cohort CORona Follow Up (CORFU) study.

Ghossein-Doha, Chahinda / Wintjens, Marieke S J N / Janssen, Emma B N J / Klein, Dorthe / Heemskerk, Stella C M / Asselbergs, Folkert W / Birnie, Erwin / Bonsel, Gouke J / van Bussel, Bas C T / Cals, Jochen W L / Ten Cate, Hugo / Haagsma, Juanita / Hemmen, Bena / van der Horst, Iwan C C / Kietselaer, Bastiaan L J H / Klok, Frederikus A / de Kruif, Martijn D / Linschoten, Marijke / van Santen, Susanne /

Vernooy, Kevin / Willems, Loes H / Westerborg, Rosa / Warle, Michiel / van Kuijk, Sander M J

BMJ open

2022 Volume 12, Issue 11, Page(s) e065142

Abstract: Introduction: The variety, time patterns and long-term prognosis of persistent COVID-19 symptoms (long COVID-19) in patients who suffered from mild to severe acute COVID-19 are incompletely understood. Cohort studies will be combined to describe the ... ...

Abstract	Introduction: The variety, time patterns and long-term prognosis of persistent COVID-19 symptoms (long COVID-19) in patients who suffered from mild to severe acute COVID-19 are incompletely understood. Cohort studies will be combined to describe the prevalence of long COVID-19 symptoms, and to explore the pathophysiological mechanisms and impact on health-related quality of life. A prediction model for long COVID-19 will be developed and internally validated to guide care in future patients. Methods and analysis: Data from seven COVID-19 cohorts will be aggregated in the longitudinal multiple cohort CORona Follow Up (CORFU) study. CORFU includes Dutch patients who suffered from COVID-19 at home, were hospitalised without or with intensive care unit treatment, needed inpatient or outpatient rehabilitation and controls who did not suffer from COVID-19. Individual cohort study designs were aligned and follow-up has been synchronised. Cohort participants will be followed up for a maximum of 24 months after acute infection. Next to the clinical characteristics measured in individual cohorts, the CORFU questionnaire on long COVID-19 outcomes and determinants will be administered digitally at 3, 6, 12, 18 and 24 months after the infection. The primary outcome is the prevalence of long COVID-19 symptoms up to 2 years after acute infection. Secondary outcomes are health-related quality of life (eg, EQ-5D), physical functioning, and the prevalence of thromboembolic complications, respiratory complications, cardiovascular diseases and endothelial dysfunction. A prediction model and a patient platform prototype will be developed. Ethics and dissemination: Approval was obtained from the medical research ethics committee of Maastricht University Medical Center+ and Maastricht University (METC 2021-2990) and local committees of the participating cohorts. The project is supported by ZonMW and EuroQol Research Foundation. Results will be published in open access peer-reviewed scientific journals and presented at (inter)national conferences. Trial registration number: NCT05240742.
MeSH term(s)	Humans ; Cohort Studies ; COVID-19/epidemiology ; Follow-Up Studies ; Prevalence ; Quality of Life ; Post-Acute COVID-19 Syndrome
Language	English
Publishing date	2022-11-29
Publishing country	England
Document type	Clinical Study ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2599832-8
ISSN	2044-6055 ; 2044-6055
ISSN (online)	2044-6055
ISSN	2044-6055
DOI	10.1136/bmjopen-2022-065142
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Article: Visualisation of coronary venous anatomy by computed tomography angiography prior to cardiac resynchronisation therapy implantation.

Nguyên, U C / Cluitmans, M J M / Luermans, J G L M / Strik, M / de Vos, C B / Kietselaer, B L J H / Wildberger, J E / Prinzen, F W / Mihl, C / Vernooy, K

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation

2018 Volume 26, Issue 9, Page(s) 433–444

Abstract: Background: The purpose of this study was to illustrate the additive value of computed tomography angiography (CTA) for visualisation of the coronary venous anatomy prior to cardiac resynchronisation therapy (CRT) implantation.: Methods: Eighteen ... ...

Abstract	Background: The purpose of this study was to illustrate the additive value of computed tomography angiography (CTA) for visualisation of the coronary venous anatomy prior to cardiac resynchronisation therapy (CRT) implantation. Methods: Eighteen patients planned for CRT implantation were prospectively included. A specific CTA protocol designed for visualisation of the coronary veins was carried out on a third-generation dual-source CT platform. Coronary veins were semi-automatically segmented to construct a 3D model. CTA-derived coronary venous anatomy was compared with intra-procedural fluoroscopic angiography (FA) in right and left anterior oblique views. Results: Coronary venous CTA was successfully performed in all 18 patients. CRT implantation and FA were performed in 15 patients. A total of 62 veins were visualised; the number of veins per patient was 3.8 (range: 2-5). Eighty-five per cent (53/62) of the veins were visualised on both CTA and FA, while 10% (6/62) were visualised on CTA only, and 5% (3/62) on FA only. Twenty-two veins were present on the lateral or inferolateral wall; of these, 95% (21/22) were visualised by CTA. A left-sided implantation was performed in 13 patients, while a right-sided implantation was performed in the remaining 2 patients because of a persistent left-sided superior vena cava with no left innominate vein on CTA. Conclusion: Imaging of the coronary veins by CTA using a designated protocol is technically feasible and facilitates the CRT implantation approach, potentially improving the outcome.
Language	English
Publishing date	2018-07-20
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	2211468-3
ISSN	1876-6250 ; 1568-5888 ; 0929-7456
ISSN (online)	1876-6250
ISSN	1568-5888 ; 0929-7456
DOI	10.1007/s12471-018-1132-2
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Article: Agatston score of the descending aorta is independently associated with coronary events in a low-risk population.

Dudink, Elton A M P / Peeters, Frederique E C M / Altintas, Sibel / Heckman, Luuk I B / Haest, Rutger J / Kragten, Hans / Kietselaer, Bas L J H / Wildberger, Joachim / Luermans, Justin G L M / Weijs, Bob / Crijns, Harry J G M

Open heart

2018 Volume 5, Issue 2, Page(s) e000893

Abstract: Objectives: A standard coronary artery calcium scan includes part of the aorta. This additional information is often not included in routine analyses. We aimed to determine the feasibility of assessing the Agatston score of the descending aorta ... ...

Abstract	Objectives: A standard coronary artery calcium scan includes part of the aorta. This additional information is often not included in routine analyses. We aimed to determine the feasibility of assessing the Agatston score of the descending aorta calcification (DAC) on standard coronary calcium scans and the association of this score with coronary events in a low-risk study population. Methods: Between January 2008 and March 2011, 390 consecutive patients who were referred for cardiac CT as part of work-up for pulmonary vein isolation (n=115) or assessment of presence of coronary artery disease (n=275) were included. At baseline, all patients were free of a history of cardiovascular disease. Two independent observers determined the Agatston score of the ascending aorta and descending aorta. Results: A total of 16 patients (4.1%) developed coronary events (acute coronary syndrome (n=6) and symptomatic significant coronary artery disease requiring treatment (n=10)) during a follow-up of 67±12 months, with more events in patients with calcifications in the descending aorta than in those without (8.4% vs 3.7 %; p=0.08). Multivariable Cox regression, corrected for Framingham Risk Score (FRS) and coronary Agatston score (CAC), revealed that DAC was independently associated with coronary events (per 100 units; HR: 1.06, 95% CI 1.02 to 1.09; p=0.001). DAC furthermore increased the identification of patients that will experience a coronary event (area under the curve: 0.68 for FRS only, 0.75 for FRS+CAC and 0.78 for FRS+CAC+DAC). Conclusions: The Agatston score of the descending aorta could be included in the standard analysis of cardiac CT scans of low-risk patients since it holds valuable information for the prediction of coronary events.
Language	English
Publishing date	2018-11-24
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2747269-3
ISSN	2053-3624 ; 2044-6055
ISSN	2053-3624 ; 2044-6055
DOI	10.1136/openhrt-2018-000893
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