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  1. Article: An Exploration of Pediatricians' Professional Identities: A Q-Methodology Study.

    Tiao, Mao-Meng / Chang, Yu-Che / Ou, Liang-Shiou / Hung, Chi-Fa / Khwepeya, Madalitso

    Healthcare (Basel, Switzerland)

    2024  Volume 12, Issue 2

    Abstract: Professional identities may influence a wide range of attitudes, ethical standards, professional commitments and patient safety. This study aimed to explore the important elements that comprise pediatricians' professional identities. A Q-methodology was ... ...

    Abstract Professional identities may influence a wide range of attitudes, ethical standards, professional commitments and patient safety. This study aimed to explore the important elements that comprise pediatricians' professional identities. A Q-methodology was used to identify the similarities and differences in professional identity. Forty pediatricians were recruited from two tertiary referral hospitals in Taiwan. A list of statements was developed by five attending physicians and three residents. R software was used to analyze the Q-sorts to load the viewpoints and formulate the viewpoint arrays. Additional qualitative data-one-to-one personal interviews-were analyzed. Twenty-eight of forty pediatricians, 11 males and 17 females, with an average age of 39.9 (27-62) years, were associated with four viewpoints. We labeled the four viewpoints identified for professional identity as (1) professional recognition, (2) patient communication, (3) empathy and (4) insight. The professional recognition viewpoint comprised of youngest participants-28-36 years-with the majority as residents (77.8%), while the empathy viewpoint comprised the oldest participants-38-62 years-with all as attending physicians. All participants in the empathy and insight viewpoints were married. This study found professional identity to be a multifaceted concept for pediatricians, especially in the areas of professional recognition, patient communication, empathy and insight into patient care.
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2721009-1
    ISSN 2227-9032
    ISSN 2227-9032
    DOI 10.3390/healthcare12020144
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Preface: Should single-incision laparoscopic appendectomy the new standard for pediatric appendicitis?

    Tang, Kuo-Shu / Tiao, Mao-Meng

    Pediatrics and neonatology

    2020  Volume 61, Issue 4, Page(s) 369–370

    Language English
    Publishing date 2020-07-07
    Publishing country Singapore
    Document type Editorial
    ZDB-ID 2441816-X
    ISSN 2212-1692 ; 1875-9572
    ISSN (online) 2212-1692
    ISSN 1875-9572
    DOI 10.1016/j.pedneo.2020.07.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Four-year-old boy with foreign body ingestion: Disk battery or coin?

    Chiang, Ming-Hsiu / Liao, Yu-Hsuan / Tiao, Mao-Meng

    Pediatrics and neonatology

    2022  Volume 63, Issue 5, Page(s) 547–548

    MeSH term(s) Eating ; Electric Power Supplies/adverse effects ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/surgery ; Humans ; Male ; Numismatics
    Language English
    Publishing date 2022-06-13
    Publishing country Singapore
    Document type Case Reports ; Journal Article
    ZDB-ID 2441816-X
    ISSN 2212-1692 ; 1875-9572
    ISSN (online) 2212-1692
    ISSN 1875-9572
    DOI 10.1016/j.pedneo.2021.11.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Prenatal High-Fat Diet Combined with Microplastic Exposure Induces Liver Injury via Oxidative Stress in Male Pups.

    Tiao, Mao-Meng / Sheen, Jiunn-Ming / Lin, I-Chun / Khwepeya, Madalitso / Yu, Hong-Ren

    International journal of molecular sciences

    2023  Volume 24, Issue 17

    Abstract: Prenatal high-fat diet (HFD) or exposure to microplastics can affect the accumulation of liver fat in offspring. We sought to determine the effects of maternal HFD intake and microplastic exposure on fatty liver injury through oxidative stress in pups. ... ...

    Abstract Prenatal high-fat diet (HFD) or exposure to microplastics can affect the accumulation of liver fat in offspring. We sought to determine the effects of maternal HFD intake and microplastic exposure on fatty liver injury through oxidative stress in pups. Pregnant female Sprague-Dawley rats were randomly divided into maternal HFD (experimental group) or normal control diet (NCD; control group) groups with or without microplastic exposure. As a result, the following groups were established: HFD-L (HFD + microplastics, 5 µm, 100 μg/L), HFD-H (HFD + microplastics, 5 µm, 1000 μg/L), NCD-L (NCD + microplastics, 5 µm, 100 μg/L), and NCD-H (NCD + microplastics, 5 µm, 1000 μg/L). The pups were sacrificed on postnatal day 7 (PD7). Liver histology revealed increased hepatic lipid accumulation in pups in the HFD-L and HFD-H groups compared to those in the HFD, NCD-L, NCD-H, and NCD groups on PD7. Similarly, liver TUNEL staining and cellular apoptosis were found to increase in pups in the HFD-L and HFD-H groups compared to those in the HFD, NCD-L, NCD-H, and NCD groups. The expression levels of malondialdehyde, a lipid peroxidation marker, were high in the HFD, HFD-L, and HFD-H groups; however, the highest expression was observed in the HFD-H group (
    MeSH term(s) Female ; Male ; Rats ; Pregnancy ; Animals ; Rats, Sprague-Dawley ; Diet, High-Fat/adverse effects ; Microplastics ; Plastics ; Noncommunicable Diseases ; Liver ; Oxidative Stress ; Vitamins
    Chemical Substances Microplastics ; Plastics ; Vitamins
    Language English
    Publishing date 2023-08-30
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms241713457
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A study on how using an interactive multimedia e-book improves teachers' ability to teach evidence-based medicine depending on their seniority.

    Liao, Yu-Hsuan / Tang, Kuo-Shu / Chen, Chih-Jen / Huang, Ying-Hsien / Tiao, Mao-Meng

    BMC medical education

    2021  Volume 21, Issue 1, Page(s) 547

    Abstract: Background: Teaching evidence-based medicine (EBM) is not an easy task. The role of the electronic book (e-book) is a useful supplement to traditional methods for improving skills. Our aim is to use an interactive e-book or PowerPoint to evaluate ... ...

    Abstract Background: Teaching evidence-based medicine (EBM) is not an easy task. The role of the electronic book (e-book) is a useful supplement to traditional methods for improving skills. Our aim is to use an interactive e-book or PowerPoint to evaluate instructors' teaching effects on EBM.
    Methods: Our study group was introduced to learning EBM using an interactive e-book available on the Internet, while the control group used a PowerPoint presentation. We adopted the Modified Fresno test to assess EBM skills both before and after their learning. EBM teaching sessions via e-book or PowerPoint were 20-30 min long, followed by students' feedback. We adopted Student's t-test to compare teachers' evaluation of their EBM skills prior to the class and the students' assessment of the teachers' instruction. We also adopted repeated measures ANCOVA to compare teachers' evaluation of their EBM skills using the Fresno test both before and after the class.
    Results: We observed no difference regarding EBM skills between the two groups prior to their experimental learning, which was assessed by the Modified Fresno test. After learning, physicians in the study group ranked higher in choosing a case to explain which kind of research design was used for the study type of the question and explaining their choice (P = 0.024) as assessed by the post-test to pre-test Fresno test. Teaching effect was better in the e-book group than in the control group for the items, "I am satisfied with this lesson," "The teaching was of high quality," "This was a good teaching method," and "It aroused my interest in EBM." However, no differences were observed between the two groups in physicians who had more than 10 years' experience.
    Conclusions: The use of interactive e-books in clinical teaching can enhance a teacher's EBM skills, though not in more senior physicians. This may suggest that teaching methodology and activities differ for teachers' varying years of experience.
    MeSH term(s) Books ; Electronics ; Evidence-Based Medicine/education ; Humans ; Learning ; Multimedia ; Teaching
    Language English
    Publishing date 2021-10-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-021-02984-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Butyrate ameliorates maternal high-fat diet-induced fetal liver cellular apoptosis.

    Huang, Yu-Jyun / Wang, Pei-Ming / Tang, Kuo-Shu / Chen, Chih-Jen / Huang, Ying-Hsien / Tiao, Mao-Meng

    PloS one

    2022  Volume 17, Issue 7, Page(s) e0270657

    Abstract: A maternal high-fat diet (HFD) can impact the offspring's development of liver steatosis, with fetal development in utero being a crucial period. Therefore, this study investigated the mechanism and whether butyrate can rescue liver injury caused by ... ...

    Abstract A maternal high-fat diet (HFD) can impact the offspring's development of liver steatosis, with fetal development in utero being a crucial period. Therefore, this study investigated the mechanism and whether butyrate can rescue liver injury caused by maternal HFD in the fetus. Pregnant female Sprague Dawley rats were randomly divided into two groups, prenatal HFD (58% fat) exposure or normal control diet (4.5% fat). The HFD group was fed an HFD 7 weeks before mating and during gestation until sacrifice at gestation 21 days. After confirmation of mating, the other HFD group was supplemented with sodium butyrate (HFSB). The results showed that maternal liver histology showed lipid accumulation with steatosis and shortened ileum villi in HFD, which was ameliorated in the HFSB group (P<0.05). There was increased fetal liver and ileum TUNEL staining and IL-6 expression with increased fetal liver TNF-α and malondialdehyde expression in the HFD group (P<0.05), which decreased in the HFSB group (P<0.05). The fetal liver expression of phospho-AKT/AKT and GPX1 decreased in the HFD group but increased in the HFSB group (P<0.05). In conclusion that oxidative stress with inflammation and apoptosis plays a vital role after maternal HFD in the fetus liver that can be ameliorated with butyrate supplementation.
    MeSH term(s) Animals ; Apoptosis ; Butyric Acid/metabolism ; Butyric Acid/pharmacology ; Diet, High-Fat ; Fatty Liver/metabolism ; Female ; Fetus/metabolism ; Pregnancy ; Proto-Oncogene Proteins c-akt/metabolism ; Rats ; Rats, Sprague-Dawley
    Chemical Substances Butyric Acid (107-92-6) ; Proto-Oncogene Proteins c-akt (EC 2.7.11.1)
    Language English
    Publishing date 2022-07-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0270657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: A study on how using an interactive multimedia e-book improves teachers’ ability to teach evidence-based medicine depending on their seniority

    Yu-Hsuan Liao / Kuo-Shu Tang / Chih-Jen Chen / Ying-Hsien Huang / Mao-Meng Tiao

    BMC Medical Education, Vol 21, Iss 1, Pp 1-

    2021  Volume 9

    Abstract: Abstract Background Teaching evidence-based medicine (EBM) is not an easy task. The role of the electronic book (e-book) is a useful supplement to traditional methods for improving skills. Our aim is to use an interactive e-book or PowerPoint to evaluate ...

    Abstract Abstract Background Teaching evidence-based medicine (EBM) is not an easy task. The role of the electronic book (e-book) is a useful supplement to traditional methods for improving skills. Our aim is to use an interactive e-book or PowerPoint to evaluate instructors’ teaching effects on EBM. Methods Our study group was introduced to learning EBM using an interactive e-book available on the Internet, while the control group used a PowerPoint presentation. We adopted the Modified Fresno test to assess EBM skills both before and after their learning. EBM teaching sessions via e-book or PowerPoint were 20–30 min long, followed by students’ feedback. We adopted Student’s t-test to compare teachers’ evaluation of their EBM skills prior to the class and the students’ assessment of the teachers’ instruction. We also adopted repeated measures ANCOVA to compare teachers’ evaluation of their EBM skills using the Fresno test both before and after the class. Results We observed no difference regarding EBM skills between the two groups prior to their experimental learning, which was assessed by the Modified Fresno test. After learning, physicians in the study group ranked higher in choosing a case to explain which kind of research design was used for the study type of the question and explaining their choice (P = 0.024) as assessed by the post-test to pre-test Fresno test. Teaching effect was better in the e-book group than in the control group for the items, “I am satisfied with this lesson,” “The teaching was of high quality,” “This was a good teaching method,” and “It aroused my interest in EBM.” However, no differences were observed between the two groups in physicians who had more than 10 years’ experience. Conclusions The use of interactive e-books in clinical teaching can enhance a teacher’s EBM skills, though not in more senior physicians. This may suggest that teaching methodology and activities differ for teachers’ varying years of experience.
    Keywords Evidenced-based medicine ; e-books ; Teaching ; Special aspects of education ; LC8-6691 ; Medicine ; R
    Subject code 370
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Using interactive multimedia e-Books for learning blood cell morphology in pediatric hematology.

    Hsiao, Chih-Cheng / Tiao, Mao-Meng / Chen, Chih-Cheng

    BMC medical education

    2016  Volume 16, Issue 1, Page(s) 290

    Abstract: Background: This prospective study compares the use of interactive multimedia eBooks (IME) with traditional PowerPoint (TPP) for teaching cell morphology of blood and bone marrow.: Methods: Fifty-one interns from three Taiwan medical schools training ...

    Abstract Background: This prospective study compares the use of interactive multimedia eBooks (IME) with traditional PowerPoint (TPP) for teaching cell morphology of blood and bone marrow.
    Methods: Fifty-one interns from three Taiwan medical schools training by a single teacher in the pediatric hematology department of Kaohsiung Chang Gung Memorial Hospital, Taiwan, participated in this study. 25 interns were allocated for training with a traditional PowerPoint atlas and 26 interns for training with an interactive multimedia eBook atlas. Learning outcomes were examined by pre-test and post-test using the CellQuiz of CellAtlas App. Attitudes and perceptions were collected by survey questions regarding interest, motivation and effectiveness.
    Results: There was no difference in the pre-test scores between TPP and IME groups (mean score 27.0 versus 27.9, p = 0.807). However, the interns in the interactive multimedia eBook group achieved significantly better scores in the post-test than the ones in the PowerPoint group (mean score 103.2 versus 70.6; p < 0.001). Overall results of interest, motivation and effectiveness were strongly positive in the multimedia eBook group.
    Conclusions: Our data supports that interactive multimedia eBooks are more effective than PowerPoint to facilitate learning of cell morphology of blood and bone marrow.
    MeSH term(s) Blood Cells ; Computer-Assisted Instruction ; Computers, Handheld ; Curriculum ; Education, Medical, Undergraduate/methods ; Educational Measurement ; Hematology/education ; Humans ; Learning ; Multimedia ; Pediatrics/education ; Prospective Studies ; Schools, Medical ; Students, Medical/psychology ; Taiwan ; Textbooks as Topic ; User-Computer Interface
    Language English
    Publishing date 2016-11-14
    Publishing country England
    Document type Comparative Study ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-016-0816-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Effects of Maternal Gut Microbiota-Targeted Therapy on the Programming of Nonalcoholic Fatty Liver Disease in Dams and Fetuses, Related to a Prenatal High-Fat Diet.

    Yu, Hong-Ren / Sheen, Jiunn-Ming / Hou, Chih-Yao / Lin, I-Chun / Huang, Li-Tung / Tain, You-Lin / Cheng, Hsin-Hsin / Lai, Yun-Ju / Lin, Yu-Ju / Tiao, Mao-Meng / Tsai, Ching-Chou

    Nutrients

    2022  Volume 14, Issue 19

    Abstract: Metabolic disorders can start in utero. Maternal transmission of metabolic phenotypes may increase the risks of adverse metabolic outcomes, such as nonalcoholic fatty liver disease (NAFLD); effective intervention is essential to prevent this. The gut ... ...

    Abstract Metabolic disorders can start in utero. Maternal transmission of metabolic phenotypes may increase the risks of adverse metabolic outcomes, such as nonalcoholic fatty liver disease (NAFLD); effective intervention is essential to prevent this. The gut microbiome plays a crucial role in fat storage, energy metabolism, and NAFLD. We investigated the therapeutic use of probiotic
    MeSH term(s) Animals ; Butyric Acid/metabolism ; Diet, High-Fat/adverse effects ; Fatty Acids, Volatile/metabolism ; Female ; Fetus/metabolism ; Gastrointestinal Microbiome ; Liver/metabolism ; Non-alcoholic Fatty Liver Disease/metabolism ; Non-alcoholic Fatty Liver Disease/therapy ; Obesity/metabolism ; Obesity/therapy ; Placenta/metabolism ; Pregnancy ; Rats ; Rats, Sprague-Dawley
    Chemical Substances Fatty Acids, Volatile ; Butyric Acid (107-92-6)
    Language English
    Publishing date 2022-09-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu14194004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Maternal Metformin Treatment Reprograms Maternal High-Fat Diet-Induced Hepatic Steatosis in Offspring Associated with Placental Glucose Transporter Modifications.

    Huang, Chien-Fu / Tiao, Mao-Meng / Lin, I-Chun / Huang, Li-Tung / Sheen, Jiunn-Ming / Tain, You-Lin / Hsu, Chien-Ning / Tsai, Ching-Chou / Lin, Yu-Ju / Yu, Hong-Ren

    International journal of molecular sciences

    2022  Volume 23, Issue 22

    Abstract: Maternal high-fat (HF) diet exposure in utero may affect fetal development and cause metabolic problems throughout life due to lipid dysmetabolism and oxidative damage. Metformin has been suggested as a potential treatment for body weight reduction and ... ...

    Abstract Maternal high-fat (HF) diet exposure in utero may affect fetal development and cause metabolic problems throughout life due to lipid dysmetabolism and oxidative damage. Metformin has been suggested as a potential treatment for body weight reduction and nonalcoholic fatty liver disease, but its reprogramming effect on offspring is undetermined. This study assesses the effects of maternal metformin treatment on hepatic steatosis in offspring caused by maternal HF diet. Female rats were fed either a control or an HF diet before conception, with or without metformin treatment during gestation, and placenta and fetal liver tissues were collected. In another experiment, the offspring were fed a control diet until 120 d (adult stage). Metformin treatment during pregnancy ameliorates placental oxidative stress and enhances placental glucose transporter 1 (
    MeSH term(s) Female ; Rats ; Pregnancy ; Animals ; Diet, High-Fat/adverse effects ; Glucose Transport Proteins, Facilitative/metabolism ; Placenta/metabolism ; Metformin/pharmacology ; Metformin/therapeutic use ; Metformin/metabolism ; Dietary Fats/pharmacology ; Non-alcoholic Fatty Liver Disease/drug therapy ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/metabolism ; AMP-Activated Protein Kinases/metabolism
    Chemical Substances Glucose Transport Proteins, Facilitative ; Metformin (9100L32L2N) ; Dietary Fats ; AMP-Activated Protein Kinases (EC 2.7.11.31)
    Language English
    Publishing date 2022-11-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms232214239
    Database MEDical Literature Analysis and Retrieval System OnLINE

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