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Book ; Online ; E-Book: Atypical breast proliferative lesions and benign breast disease

Amersi, Farin / Calhoun, Kristine

2018

Author's details	Farin Amersi, Kristine Calhoun editors
Keywords	Surgery ; Surgical oncology ; Oncology ; Pathology
Subject code	617
Language	English
Size	1 Online-Ressource (xi, 197 Seiten), Illustrationen
Publisher	Springer
Publishing place	Cham
Publishing country	Switzerland
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT019860866
ISBN	978-3-319-92657-5 ; 9783319926568 ; 3-319-92657-8 ; 331992656X
DOI	10.1007/978-3-319-92657-5
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article ; Online: Response to Letter to the Editor: "18FDG-PET/CT Imaging in Breast Cancer Patients with Clinical Stage IIB or Higher".

Srour, Marissa K / Amersi, Farin

Annals of surgical oncology

2020 Volume 27, Issue 5, Page(s) 1710–1711

MeSH term(s)	Breast Neoplasms ; Fluorodeoxyglucose F18 ; Humans ; Neoadjuvant Therapy ; Positron Emission Tomography Computed Tomography ; Positron-Emission Tomography ; Radiopharmaceuticals
Chemical Substances	Radiopharmaceuticals ; Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2020-01-06
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-019-08194-x
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Article ; Online: Competence Is About Skill, Not Procedure Case Numbers-Reply.

Purdy, Amanda C / de Virgilio, Christian / Amersi, Farin

JAMA surgery

2021 Volume 157, Issue 1, Page(s) 81–82

MeSH term(s)	Exercise ; Humans ; Motor Skills
Language	English
Publishing date	2021-09-15
Publishing country	United States
Document type	Journal Article ; Comment
ZDB-ID	2701841-6
ISSN	2168-6262 ; 2168-6254
ISSN (online)	2168-6262
ISSN	2168-6254
DOI	10.1001/jamasurg.2021.4415
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Article ; Online: A Prospective Study of Sentinel Node Biopsy Omission in Women Age ≥ 65 Years with ER+ Breast Cancer.

Chung, Alice P / Dang, Catherine M / Karlan, Scott R / Amersi, Farin F / Phillips, Edward M / Boyle, Marissa K / Cui, Yujie / Giuliano, Armando E

Annals of surgical oncology

2024 Volume 31, Issue 5, Page(s) 3160–3167

Abstract: Background: National guidelines recommend omitting SNB in older patients with favorable invasive breast cancer. However, there is a lack of prospective data specifically addressing this issue. This study evaluates recurrence and survival in estrogen ... ...

Abstract	Background: National guidelines recommend omitting SNB in older patients with favorable invasive breast cancer. However, there is a lack of prospective data specifically addressing this issue. This study evaluates recurrence and survival in estrogen receptor-positive/Her2- (ER+) breast cancer patients, aged ≥ 65 years who have breast-conserving surgery (BCS) without SNB. Methods: This is a prospective, observational study at a single institution where 125 patients aged ≥ 65 years with clinical T1-2N0 ER+ invasive breast cancer undergoing BCS were enrolled. Patients were treated with BCS without SNB. Primary outcome measure was axillary recurrence. Secondary outcome measures include recurrence-free survival (RFS), disease-free survival (DFS), breast cancer-specific survival (BCSS), and overall survival (OS). Results: From January 2016 to July 2022, 125 patients were enrolled with median follow-up of 36.7 months [95% confidence interval (CI) 35.0-38.0]. Median age was 77.0 years (range 65-93). Median tumor size was 1 cm (range 0.1-5.0). Most tumors were ductal (95/124, 77.0%), intermediate grade (60/116, 51.7%), and PR-positive (117/123, 91.7%). Radiation therapy was performed in 37 of 125 (29.6%). Only 60 of 125 (48.0%) who were recommended hormonal therapy were compliant at 2 years. Chemotherapy was administered to six of 125 (4.8%) patients. There were two of 125 (1.6%) axillary recurrences. Estimated 3-years rates of regional RFS, DFS, and OS were 98.2%, 91.2%, and 94.8%, respectively. Univariate Cox regression identified hormonal therapy noncompliance to be significantly associated with recurrence (p = 0.02). Conclusions: Axillary recurrence rates were extremely low in this cohort. These results provide prospective data to support omission of SNB in this patient population TRIAL REGISTRATION: ClinicalTrials.gov ID NCT02564848.
MeSH term(s)	Humans ; Female ; Aged ; Aged, 80 and over ; Breast Neoplasms/surgery ; Breast Neoplasms/drug therapy ; Prospective Studies ; Follow-Up Studies ; Sentinel Lymph Node Biopsy ; Mastectomy, Segmental/methods ; Axilla/pathology ; Lymph Node Excision/methods ; Neoplasm Recurrence, Local/surgery
Language	English
Publishing date	2024-02-12
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-024-15000-w
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Article ; Online: The Fellow's Perspective: The Impact of the COVID-19 Pandemic on Fellowship Training and Job Appointment.

Truong, Adam / Amersi, Farin / Chau, Van / Imai, Taryne

The American surgeon

2021 Volume 87, Issue 10, Page(s) 1678–1683

Abstract: Background: Fellows have been uniquely affected by the widespread changes in educational structure, mandatory limitations in elective procedural volume, and hiring freezes during the COVID-19 global pandemic.: Study design: A voluntary and anonymous ... ...

Abstract	Background: Fellows have been uniquely affected by the widespread changes in educational structure, mandatory limitations in elective procedural volume, and hiring freezes during the COVID-19 global pandemic. Study design: A voluntary and anonymous survey was distributed to all Graduate Medical Education fellows at a tertiary medical center querying perspectives on clinical and didactic training and job placement. Results: A total of 47 of 121 fellows (39%) completed the survey. The majority were in a medical (43%) or surgical specialty (34%) followed by critical care (13%) and procedure-based (11%) fellowships. Approximately 59% of surveyed fellows felt their programs were providing a virtual curriculum that would train them just as well as the in-person curriculum. Twenty-eight (60%) fellows were in their final or only year of training. Of the 25 fellows who were seeking employment, 52% have experienced difficulty in finding a job due to hiring freezes and 40% have encountered challenges with job interview cancellations and changes to virtual interview formats. Conclusion: Almost half of surveyed fellows reported an educational deterioration due to COVID-19 and graduating fellows seeking employment felt hindered by both the virtual interview format and widespread hiring freeze. Fellows are both unique and vulnerable as they balance the solidification of clinical training with securing employment during these tumultuous and unprecedented times.
MeSH term(s)	Adult ; COVID-19/epidemiology ; California/epidemiology ; Education, Medical, Graduate/standards ; Employment/statistics & numerical data ; Fellowships and Scholarships ; Female ; Humans ; Male ; Pandemics ; SARS-CoV-2 ; Surveys and Questionnaires
Language	English
Publishing date	2021-06-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
DOI	10.1177/00031348211024195
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Article ; Online: Surveillance Strategies Following Prophylactic Nipple-Sparing Mastectomy in BRCA Mutation Carriers.

Weed, Christina / Wang, Ton / Fat, Shelby Chun / Chung, Alice / Boyle, Marissa K / Giuliano, Armando / Amersi, Farin

Annals of surgical oncology

2023 Volume 30, Issue 9, Page(s) 5335–5336

MeSH term(s)	Humans ; Female ; Mastectomy ; Nipples/surgery ; Breast Neoplasms/genetics ; Breast Neoplasms/prevention & control ; Breast Neoplasms/surgery ; Mastectomy, Subcutaneous ; Mutation ; Mammaplasty
Language	English
Publishing date	2023-06-26
Publishing country	United States
Document type	Letter
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-023-13717-8
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Article ; Online: Use of the End to End Anastomotic Stapler From Above for Difficult Pelvic Surgery for Distal Rectal Disease.

Amersi, Farin F / Wright, Byron / Silberman, Allan W

The American surgeon

2020 Volume 87, Issue 8, Page(s) 1313–1315

Abstract: Introduction: Transabdominal utilization (TAU) of the end to end anastomotic (EEA) stapler in low anterior resection (LAR) for rectal cancer is an excellent alternative to the most widely performed techhnique.: Methods: We performed a retrospective ... ...

Abstract	Introduction: Transabdominal utilization (TAU) of the end to end anastomotic (EEA) stapler in low anterior resection (LAR) for rectal cancer is an excellent alternative to the most widely performed techhnique. Methods: We performed a retrospective analysis of a prospectively maintained database which obtained data on 104 patients with rectal disease who underwent EEA-assisted LAR with TAU. Records of all patients were used to evaluate demographics, complications, tumor location, margin status, postoperative complications, clinical sphincter function, adjuvant or neoadjuvant treatment, disease stage, and survival. Results: Of the 104 patients, 48% were women with a mean age of 64 years (range 34-85 years). The average tumor location was 8 cm above the dentate line, and the mean tumor distance from the distal margin was 1.9 cm. All distal margins in cases for patients with rectal cancer were negative. Hospital length of stay averaged 8.7 days (6-15 days). There were no anastomotic complications (leaks, bleeding, or obstruction), and there were no leaks at the separate colotomy site. All patients have had normal postoperative sphincter function. Conclusion: Transabdominal utilization of the EEA stapler in LAR for colorectal carcinoma is an alternative to the conventional approach and may be advantageous in avoidance of the lithotomy position with potential nerve injury, risk of deep venous thrombosis, and stapler-induced sphincter trauma.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Anal Canal/physiology ; Anal Canal/surgery ; Anastomosis, Surgical/adverse effects ; Anastomosis, Surgical/instrumentation ; Colon/surgery ; Female ; Humans ; Length of Stay ; Male ; Margins of Excision ; Middle Aged ; Postoperative Complications ; Rectal Neoplasms/surgery ; Rectum/surgery ; Retrospective Studies ; Surgical Staplers
Language	English
Publishing date	2020-12-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
DOI	10.1177/0003134820971626
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Article ; Online: Secondary Malignancies: The Cost of Progress.

Silberman, Allan W / Quadri, Humair S / Amersi, Farin

The American surgeon

2020 Volume 87, Issue 9, Page(s) 1368–1373

Abstract: Background: With advances in treatment of cancer, patients who survive their first malignancy are at risk of developing additional malignancies. Data on the risks of secondary malignancies after treatment of some of the more common cancers are lacking.!# ...

Abstract	Background: With advances in treatment of cancer, patients who survive their first malignancy are at risk of developing additional malignancies. Data on the risks of secondary malignancies after treatment of some of the more common cancers are lacking. Methods: Our prospectively maintained database was queried from 1996 to 2016 to identify patients with breast cancer, colorectal cancer, melanoma, sarcoma, gastric, and pancreatic adenocarcinoma who developed additional malignancies. Predisposing clinical factors were included in our analysis. Results: We identified 756 patients diagnosed with a solid malignancy who developed a second malignancy, of which 606 (80.1%) had one of the most common treated cancers. 59.5% of patients were women. 810 additional malignancies were identified in the 606 patients with breast and colon cancer being the most common secondary malignancies. Of these 606 patients, 460 (76%) patients had two malignancies; 145 (23.9%) had 3 or more malignancies. 15.2% of patients were diagnosed under the age of 40.63 years. 8.3% patients had a known genetic mutation, with BReast CAncer gene, and Lynch mutations being the most common. Conclusion: Advances in cancer treatment have led to higher cure rates. These patients should continue surveillance and undergo screening as they may be at risk of developing additional malignancies.
MeSH term(s)	Adult ; Aged ; Female ; Humans ; Male ; Mass Screening/methods ; Middle Aged ; Neoplasms, Multiple Primary/diagnosis ; Neoplasms, Multiple Primary/therapy ; Population Surveillance ; Prospective Studies ; Risk Factors
Language	English
Publishing date	2020-12-22
Publishing country	United States
Document type	Journal Article
ZDB-ID	202465-2
ISSN	1555-9823 ; 0003-1348
ISSN (online)	1555-9823
ISSN	0003-1348
DOI	10.1177/0003134820960081
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Article ; Online: Practice Patterns of Antibiotic Prophylaxis in Patients Undergoing Mastectomy: A Survey of Members of the American Society of Breast Surgeons.

Sattar, Abida K / Shahzad, Hania / Masroor, Taleaa / Martins, Russell Seth / Zahid, Nida / Amersi, Farin F

Annals of surgical oncology

2022 Volume 29, Issue 10, Page(s) 6314–6322

Abstract: Background: Surgical site infections after breast surgery range from 1 to 16%. Both the American Society of Breast Surgeons (ASBrS) and the American Association of Plastic Surgeons guidelines lack clarity on postoperative antibiotic prophylaxis (AP) ... ...

Abstract	Background: Surgical site infections after breast surgery range from 1 to 16%. Both the American Society of Breast Surgeons (ASBrS) and the American Association of Plastic Surgeons guidelines lack clarity on postoperative antibiotic prophylaxis (AP) after mastectomy. We surveyed the ASBrS membership to understand their practice patterns of AP after mastectomy and familiarity with ASBrS guidelines. Methods: A self-designed, 19-question survey was emailed to all 2934 ASBrS members. Information was obtained on the participants' training, familiarity with ASBrS guidelines, and practices of prescribing perioperative AP after mastectomy with/without reconstruction and with indwelling drains. Results: In total, 556 (19%) responses were analyzed. Half were fellowship-trained breast surgeons/surgical oncologists (50.2%), with 55.6% having practiced for > 15 years and 66.9% in community/private practice. Only 53.6% reported familiarity with ASBrS guidelines for perioperative AP. Most (> 90%) surgeons reported "always" placing drains after mastectomy and "always" prescribing preoperative AP. Postoperatively, preference for continuing AP in cases with drains in place varied by procedure: 7.7% when no reconstruction, 29.1% when autologous-only, and 52.5% when implant reconstruction. Academic surgeons were less likely than surgeons in community/private practice to continue postoperative AP, whether for the duration of indwelling drains (5.1% versus 9.4%) or even till 7 days postoperatively (0.6% versus 3.2%) (p < 0.05). Conclusions: Surgeons uniformly adhere to ASBrS guidelines for preoperative AP. However, there is wide variation in AP postoperatively in patients with/without reconstruction and with indwelling drains. Our results highlight the need for high-quality evidence based on which guidelines must be updated, and the need to familiarize surgeons with current guidelines.
MeSH term(s)	Antibiotic Prophylaxis ; Breast Neoplasms/surgery ; Female ; Humans ; Mammaplasty/methods ; Mastectomy/adverse effects ; Mastectomy/methods ; Practice Patterns, Physicians' ; Surgeons ; United States
Language	English
Publishing date	2022-07-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-022-12223-7
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Article ; Online: Comparison of Clinical Breast Exam to Breast MRI Surveillance in Patients Following Nipple-Sparing Mastectomy.

Weed, Christina / Wang, Ton / Mohan, Srivarshini C / Wang, Xuanji / Tseng, Joshua / Hu, Theodore / Jaswinder, Jutla / Boyle, Marissa K / Amersi, Farin / Giuliano, Armando / Chung, Alice

Clinical breast cancer

2024

Abstract: Background: Nipple sparing mastectomy (NSM) is increasingly being performed for patients with breast cancer. However, optimal postoperative surveillance has not been defined.: Methods: A prospectively maintained database identified patients with in- ... ...

Abstract	Background: Nipple sparing mastectomy (NSM) is increasingly being performed for patients with breast cancer. However, optimal postoperative surveillance has not been defined. Methods: A prospectively maintained database identified patients with in-situ and invasive cancer who underwent NSM between 2007-2021. Clinical data on postoperative breast surveillance and interventions were collected. Patients who had MRI surveillance versus clinical breast exam (CBE) alone were compared with respect to tumor characteristics, recurrence, and survival. Results: A total of 483 NSMs were performed on 399 patients. 255 (63.9%) patients had invasive ductal carcinoma, 31 (7.8%) invasive lobular carcinoma, 92 (23.1%) DCIS, 6 (1.5%) mixed ductal and lobular carcinoma, 9 (2.3%) others, and 6 (1.5%) unknown. Postoperatively, 265 (66.4%) patients were followed with CBE alone and 134 (33.6%) had surveillance MRIs. At a median follow-up of 33 months, 20 patients (5.0%) developed in-breast recurrence, 6 patients had (1.5%) an axillary recurrence, and 28 with (7.0%) distant recurrence. 14 (53.8%) LRR were detected in the CBE group and 12 (46.2%) were detected in the MRI group (P = .16). Overall survival (OS) was 99%, with no difference in OS between patients who had CBE alone versus MRI (P = .46). MRI was associated with higher biopsy rates compared to CBE alone (15.8% vs. 7.8%, P = .01). Conclusions: Compared to CBE alone, the use of screening MRI following NSM results in higher rate of biopsy and no difference in overall survival.
Language	English
Publishing date	2024-03-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	2106734-X
ISSN	1938-0666 ; 1526-8209
ISSN (online)	1938-0666
ISSN	1526-8209
DOI	10.1016/j.clbc.2024.03.011
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