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  1. Article: Rhabdomyolysis due to warfarin and atorvastatin combination therapy in a patient with ischemic heart disease: (A drug interaction).

    Soliemanabad, Saeed Kargar / Rasouli, Kimia / Zakariaei, Zakaria / Soleymani, Mostafa / Aliabadi, Parastoo Karimi

    Annals of medicine and surgery (2012)

    2022  Volume 75, Page(s) 103384

    Abstract: Introduction: Although atorvastatin has serious adverse effects, including hepatotoxicity and myopathy, it can cause drug interactions and side effects such as rhabdomyolysis and acute kidney injury, especially when combined with warfarin, which uses ... ...

    Abstract Introduction: Although atorvastatin has serious adverse effects, including hepatotoxicity and myopathy, it can cause drug interactions and side effects such as rhabdomyolysis and acute kidney injury, especially when combined with warfarin, which uses the same enzyme pathway for metabolism.
    Case presentation: We describe a 66-year-old man with a history of ischemic heart disease who developed renal complications and rhabdomyolysis after concomitant use of atorvastatin and warfarin.
    Discussion: Statins reduce serum LDL cholesterol levels significantly. It is a safe and cost-effective medicine used in the treatment of DLP as well as the primary and secondary prevention of CAD, atherosclerosis, myocardial infarction, and stroke. Despite their benefits, statins can cause side effects in various organs of the body, including the gastrointestinal tract, CNS, liver, and kidneys.
    Conclusion: Statins are widely prescribed to patients with cardiovascular problems. Therefore, clinicians should pay attention to the patient's medical history, current prescribed doses, and drug interactions when adding new drugs or adjusting existing drugs.
    Language English
    Publishing date 2022-02-12
    Publishing country England
    Document type Case Reports
    ZDB-ID 2745440-X
    ISSN 2049-0801
    ISSN 2049-0801
    DOI 10.1016/j.amsu.2022.103384
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Impact of Fasting on Metabolic and Anthropometric Parameters in Type II Diabetic Patients

    Tayebeh Yazdanyar / Mehrnoush Sohrab / Atena Ramezani / Parastoo Karimi Aliabadi / Adele Bahar / Mahboobeh Shirzad / Elham Yousefi Abdolmaleki / Mohsen Aarabi

    Journal of Clinical and Diagnostic Research, Vol 14, Iss 12, Pp OC18-OC

    A Prospective Observational Study

    2020  Volume 23

    Abstract: Introduction: Fasting has certain effects on metabolic and anthropometric parameters in diabetic patients. It is therefore, necessary for patients to receive proper instructions about their physical activities, eating habits, blood glucose monitoring and ...

    Abstract Introduction: Fasting has certain effects on metabolic and anthropometric parameters in diabetic patients. It is therefore, necessary for patients to receive proper instructions about their physical activities, eating habits, blood glucose monitoring and medications. Aim: To investigate the effects of fasting on metabolic and anthropometric indices in type II diabetic patients. Materials and Methods: This prospective observational study was performed during Ramadan 2018. The study population consisted of 40 type II diabetic patients (33 females and 7 males) who wished to fast. They started to follow given instructions on their physical activity, eating habits, blood glucose monitoring, and medications before Ramadan. Anthropometric variables were measured pre and post-Ramadan. Fasting Blood/Plasma Glucose (FBG/FPG), Glucose 2 Hour Postprandial (2h PPG), glycosylated haemoglobin (HbA1c), and the lipids profile were assessed before and after Ramadan. FPG and 2h PPG were also evaluated on the fifteenth day of Ramadan. Data were presented as mean±SD. Paired t-test was employed and a p-value of <0.05 was considered statistically significant. Results: After completion of the study, anthropometric variables of patients, including weight (74.9±12.7 vs. 73.0±13.1 kg, p<0.001), BMI (29.9±5.2 vs. 29.0±5.1 kg/m2 , p=0.042), waist circumference (106.2±11.8 vs. 105.3±11.6 cm, p<0.001), conicity index (9.94±0.96 vs 9.80±0.99, p=0.085), systolic blood pressure (118.5±10.6 vs. 113.8±9.4 mmHg, p=0.018), Diastolic blood pressure (72.0±7.9 vs. 68.3±7.0 mmHg, p=0.02) and FPG (125.1±27.4 vs. 105.2±21.4 mg/dL, p<0.001) decreased significantly. However, serum triglyceride increased significantly (127.5±45.5 vs. 166.5±53.5 mg/dL, p<0.001) after fasting compared to pre-Ramadan measurements. Changes in other variables were not statistically significant. Conclusion: The results of this study indicate that fasting had beneficial effect on fasting blood glucose level and anthropometric parameters in type II diabetic patients.
    Keywords blood glucose ; body mass index ; cholesterol low density lipoprotein ; conicity index ; family physician ; high density lipoprotein cholesterol ; waist to hip ratio ; Medicine ; R
    Subject code 796 ; 610
    Language English
    Publishing date 2020-12-01T00:00:00Z
    Publisher JCDR Research and Publications Private Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: The role of spiritual intelligence in predicting the empathy levels of nurses with COVID-19 patients.

    Aliabadi, Parastoo Karimi / Zazoly, Atefeh Zabihi / Sohrab, Mehrnoush / Neyestani, Farkhondeh / Nazari, Nahid / Mousavi, Seyed Hassan / Fallah, Abolghasem / Youneszadeh, Majid / Ghasemiyan, Masoumeh / Ferdowsi, Mohammad

    Archives of psychiatric nursing

    2021  Volume 35, Issue 6, Page(s) 658–663

    Abstract: Aim: Given the prolongation of the newly emerging COVID-19 pandemic and the significance of caring for the patients by nursing staff, investigating and planning for the different psychological dimensions of this group is of paramount importance. Hence, ... ...

    Abstract Aim: Given the prolongation of the newly emerging COVID-19 pandemic and the significance of caring for the patients by nursing staff, investigating and planning for the different psychological dimensions of this group is of paramount importance. Hence, this study investigated the role of spiritual intelligence in predicting nurses' empathizing with COVID-19 patients.
    Methods: This descriptive-correlation study was conducted in 2021 on nurses caring for COVID-19 patients in three public hospitals. The researchers used two standard questionnaires, including the Jefferson Scale of Empathy (JSE) and Spiritual Intelligence (SI), for data collection. The collected data were analyzed in SPSS16 using descriptive statistics and the following: The Mann-Whitney U test, Kruskal-Wallis test, Regression, chi-square test, and Pearson and Spearman correlations.
    Results: The statistical population consisted of 338 nurses with an average age of 34 and ten years of work experience. There was a significant positive relationship between the empathy scores and spiritual intelligence scores of the nurses caring for COVID-19 patients (P < 0.05). It was also concluded from the regression analysis that, spiritual intelligence affect empathy. Mean score of empathy was higher in hospitals where more nursing staff had MSc degrees. There was a significant difference between the empathy scores of the three hospitals (P < 0.05).
    Conclusion: The results indicated that there is a positive relationship between empathy and spiritual intelligence. Therefor improving spiritual intelligence is the appropriate strategy to ameliorate empathy during the COVID19 pandemic. At the same time, study indicated attention to the issue of nurses' mental health. Hence, it was suggested to incorporate these issues in the training programs and national/international decisions.
    MeSH term(s) Adult ; COVID-19 ; Empathy ; Humans ; Intelligence ; Pandemics ; SARS-CoV-2 ; Surveys and Questionnaires
    Language English
    Publishing date 2021-10-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639197-7
    ISSN 1532-8228 ; 0883-9417
    ISSN (online) 1532-8228
    ISSN 0883-9417
    DOI 10.1016/j.apnu.2021.10.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Association between liver enzymes and metabolic syndrome: results of the enrollment phase of Tabari cohort.

    Aliabadi, Parastoo Karimi / Sohrab, Mehrnoush / Hessami, Amirhossein / Afshari, Mahdi / Kashi, Zahra / Kheradmand, Motahareh / Hedayatizadeh-Omran, Akbar / Alizadeh-Navaei, Reza / Moosazadeh, Mahmood

    Irish journal of medical science

    2021  Volume 191, Issue 3, Page(s) 1201–1208

    Abstract: Background: The association between liver enzymes and metabolic syndrome (MetS) has been evaluated in several studies with different results. The purpose of this study is to determine the association between the serum levels of these liver enzymes and ... ...

    Abstract Background: The association between liver enzymes and metabolic syndrome (MetS) has been evaluated in several studies with different results. The purpose of this study is to determine the association between the serum levels of these liver enzymes and MetS in Tabari cohort population.
    Method: In this case-control study, data collected from the enrolment phase of the Tabari cohort population have been used. MetS was defined based on IDF (international diabetes federation) standards. Then, 476 patients with MetS (case group) and 476 age-sex matched controls were selected randomly.
    Results: Mean aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were higher in case group than control group (20.59 vs. 19.99 respectively, p = 0.339 and 24.64 vs. 20.16 respectively, p < 0.001). The chance of having MetS, high triglyceride, and fasting blood glucose (FBG) was significantly higher in people with ALT ≥ 40 (1.63, 2.35, and 2.02, respectively). The chance of having MetS in people with AST ≥ 40 was 1.45 times higher than that among those with normal AST level (p > 0.05).
    Conclusion: This study showed that there is an association between liver enzymes and MetS as well as some of its components. Liver enzymes, especially ALT, can be used as an early indicator of MetS in the at risk population.
    MeSH term(s) Alanine Transaminase/metabolism ; Aspartate Aminotransferases ; Case-Control Studies ; Humans ; Liver/metabolism ; Metabolic Syndrome/complications ; Metabolic Syndrome/epidemiology
    Chemical Substances Aspartate Aminotransferases (EC 2.6.1.1) ; Alanine Transaminase (EC 2.6.1.2)
    Language English
    Publishing date 2021-06-25
    Publishing country Ireland
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 390895-1
    ISSN 1863-4362 ; 0021-1265
    ISSN (online) 1863-4362
    ISSN 0021-1265
    DOI 10.1007/s11845-021-02694-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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