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  1. Article ; Online: Letter to the Editor From Jialal: "Higher Incidence of Metabolic Syndrome in Black Women With Polycystic Ovary Syndrome: A Longitudinal Study".

    Jialal, Ishwarlal

    The Journal of clinical endocrinology and metabolism

    2022  Volume 107, Issue 5, Page(s) e2198–e2199

    MeSH term(s) Female ; Humans ; Hyperandrogenism/complications ; Incidence ; Insulin Resistance ; Longitudinal Studies ; Male ; Metabolic Syndrome/epidemiology ; Metabolic Syndrome/etiology ; Polycystic Ovary Syndrome/complications ; Polycystic Ovary Syndrome/epidemiology ; Polycystic Ovary Syndrome/metabolism
    Language English
    Publishing date 2022-01-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 3029-6
    ISSN 1945-7197 ; 0021-972X
    ISSN (online) 1945-7197
    ISSN 0021-972X
    DOI 10.1210/clinem/dgab935
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chemerin levels in metabolic syndrome: a promising biomarker.

    Jialal, Ishwarlal

    Archives of physiology and biochemistry

    2021  Volume 129, Issue 5, Page(s) 1009–1011

    MeSH term(s) Humans ; Metabolic Syndrome/diagnosis ; Metabolic Syndrome/metabolism ; Biomarkers ; Obesity/metabolism ; Chemokines
    Chemical Substances Biomarkers ; Chemokines
    Language English
    Publishing date 2021-04-12
    Publishing country England
    Document type Editorial
    ZDB-ID 1238320-x
    ISSN 1744-4160 ; 1381-3455
    ISSN (online) 1744-4160
    ISSN 1381-3455
    DOI 10.1080/13813455.2021.1912103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Management of diabetic dyslipidemia: Navigating the new American and European Guidelines.

    Jialal, Ishwarlal

    Diabetes & metabolic syndrome

    2020  Volume 14, Issue 5, Page(s) 877–879

    Language English
    Publishing date 2020-06-08
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2273766-2
    ISSN 1878-0334 ; 1871-4021
    ISSN (online) 1878-0334
    ISSN 1871-4021
    DOI 10.1016/j.dsx.2020.06.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Bempedoic Acid, an Inhibitor of Cholesterol Biosynthesis, Reduces Cardiovascular Events.

    Jialal, Ishwarlal / Olatunbosun, Samuel

    Journal of clinical medicine

    2023  Volume 12, Issue 10

    Abstract: An elevated low-density lipoprotein cholesterol (LDL-C) is a major risk factor for premature atherosclerotic cardiovascular diseases (ASCVD) [ ... ]. ...

    Abstract An elevated low-density lipoprotein cholesterol (LDL-C) is a major risk factor for premature atherosclerotic cardiovascular diseases (ASCVD) [...].
    Language English
    Publishing date 2023-05-14
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12103463
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Validation of Fibroblast Growth Factor 23 Assays.

    Jialal, Ishwarlal

    The journal of applied laboratory medicine

    2020  Volume 5, Issue 4, Page(s) 819–821

    MeSH term(s) Biomarkers/blood ; Disease Progression ; Fibroblast Growth Factors/blood ; Glomerular Filtration Rate ; Humans ; Ontario/epidemiology ; Prospective Studies ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/mortality ; Renal Insufficiency, Chronic/therapy ; Renal Replacement Therapy/statistics & numerical data ; Risk Assessment/methods ; Severity of Illness Index
    Chemical Substances Biomarkers ; Fibroblast Growth Factors (62031-54-3) ; fibroblast growth factor 23 (7Q7P4S7RRE)
    Language English
    Publishing date 2020-06-30
    Publishing country England
    Document type Letter ; Validation Study
    ISSN 2576-9456
    ISSN 2576-9456
    DOI 10.1093/jalm/jfaa026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The Evolving Role of C-Reactive Protein in Heart Failure: Implications for Patients With Cardiovascular Disease.

    Jialal, Ishwarlal / Ebong, Imo A

    Journal of the American College of Cardiology

    2023  Volume 82, Issue 5, Page(s) 427–429

    MeSH term(s) Humans ; C-Reactive Protein/metabolism ; Cardiovascular Diseases ; Heart Failure/metabolism ; Biomarkers ; Stroke Volume
    Chemical Substances C-Reactive Protein (9007-41-4) ; Biomarkers
    Language English
    Publishing date 2023-05-20
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.05.036
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Syndromes of autoantibodies to the insulin receptor.

    Jialal, Ishwarlal / Basheer, Hiba

    International journal of biochemistry and molecular biology

    2022  Volume 13, Issue 6, Page(s) 87–91

    Language English
    Publishing date 2022-12-15
    Publishing country United States
    Document type Editorial
    ZDB-ID 2588039-1
    ISSN 2152-4114
    ISSN 2152-4114
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Correlates of Insulin Resistance in Nascent Metabolic Syndrome.

    Adams-Huet, Beverley / Jialal, Ishwarlal

    Clinical medicine insights. Endocrinology and diabetes

    2023  Volume 16, Page(s) 11795514231168279

    Abstract: Background: Metabolic Syndrome (MetS), a major global problem, is a cluster of cardio-metabolic risk factors that predisposes to both type 2 diabetes mellitus (T2DM) and premature atherosclerotic cardiovascular disease (ASCVD). Insulin resistance is a ... ...

    Abstract Background: Metabolic Syndrome (MetS), a major global problem, is a cluster of cardio-metabolic risk factors that predisposes to both type 2 diabetes mellitus (T2DM) and premature atherosclerotic cardiovascular disease (ASCVD). Insulin resistance is a major underpinning of MetS.
    Objectives: We investigated the relationship between insulin resistance and biomarkers of inflammation, oxidative stress, free fatty acids (FFA) levels and adipokine dysregulation in a cohort of nascent MetS.
    Design: This was a cross-sectional study comparing patients with MetS with matched controls.
    Patients and methods: Participants included 47 patients with MetS and 41 controls. Persons with diabetes, ASCVD, smoking and macro-inflammation were excluded. Fasting blood was obtained for both plasma and monocyte isolation. Homeostasis model assessment insulin resistance index (HOMA-IR) was calculated from fasting glucose and insulin levels.
    Results: The patients were insulin resistant as determined by a valid measure, HOMA-IR. HOMA-IR increased with increasing severity of MetS and correlated with cardio-metabolic features, hsCRP, FFA levels, and adipose tissue insulin resistance. Insulin resistance also correlated with biomarkers of oxidative stress and both circulating and cellular biomarkers of inflammation. Receiver operating Characteristic (ROC) curve analysis revealed that HOMA-IR was an excellent predictor of MetS with an area under the curve of 0.80.
    Conclusion: In our patients with nascent MetS we show that they have significant insulin resistance. Based on our findings, elevated FFA levels, oxidative stress and inflammation could contribute to the insulin resistance.
    Language English
    Publishing date 2023-04-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2628990-8
    ISSN 1179-5514
    ISSN 1179-5514
    DOI 10.1177/11795514231168279
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book: Handbook of diagnostic endocrinology

    Jialal, Ishwarlal

    1999  

    Author's details ed. by Ishwarlal Jialal
    Language English
    Size 275 S. : graph. Darst.
    Publisher AACC Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    HBZ-ID HT011214849
    ISBN 1-890883-08-5 ; 978-1-890883-08-9
    Database Catalogue ZB MED Medicine, Health

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  10. Article: Increased Adipocyte Hypertrophy in Patients with Nascent Metabolic Syndrome.

    Jialal, Ishwarlal / Adams-Huet, Beverley / Devaraj, Sridevi

    Journal of clinical medicine

    2023  Volume 12, Issue 13

    Abstract: Background and Aims: ...

    Abstract Background and Aims:
    Language English
    Publishing date 2023-06-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12134247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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