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  1. Article ; Online: Cancer matters: Now more than ever!

    Ramalingam, Suresh S

    Cancer

    2021  Volume 127, Issue 13, Page(s) 2174–2176

    MeSH term(s) Humans ; Immunotherapy ; Neoplasms/epidemiology ; Neoplasms/therapy
    Language English
    Publishing date 2021-06-11
    Publishing country United States
    Document type Editorial
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.33669
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Neoadjuvant therapy gains FDA approval in non-small cell lung cancer.

    Leal, Ticiana A / Ramalingam, Suresh S

    Cell reports. Medicine

    2022  Volume 3, Issue 7, Page(s) 100691

    Abstract: Forde et al. ...

    Abstract Forde et al.
    MeSH term(s) Antineoplastic Agents, Immunological/administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Humans ; Lung Neoplasms/drug therapy ; Neoadjuvant Therapy ; Nivolumab/administration & dosage ; Progression-Free Survival
    Chemical Substances Antineoplastic Agents, Immunological ; Nivolumab (31YO63LBSN)
    Language English
    Publishing date 2022-07-13
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial ; Comment
    ISSN 2666-3791
    ISSN (online) 2666-3791
    DOI 10.1016/j.xcrm.2022.100691
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The National Cancer Act of 1971: A seminal milestone in the fight against cancer.

    Ramalingam, Suresh S / Khuri, Fadlo R

    Cancer

    2021  Volume 127, Issue 24, Page(s) 4532–4533

    MeSH term(s) Humans ; Immunotherapy ; Neoplasms/therapy
    Language English
    Publishing date 2021-12-07
    Publishing country United States
    Document type Editorial
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.34001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Harnessing CD8 T cell responses using PD-1-IL-2 combination therapy.

    Hashimoto, Masao / Ramalingam, Suresh S / Ahmed, Rafi

    Trends in cancer

    2023  Volume 10, Issue 4, Page(s) 332–346

    Abstract: There is considerable interest in developing more effective programmed cell death (PD)-1 combination therapies against cancer. One major obstacle to these efforts is a dysfunctional/exhausted state of CD8 T cells, which PD-1 monotherapy is not able to ... ...

    Abstract There is considerable interest in developing more effective programmed cell death (PD)-1 combination therapies against cancer. One major obstacle to these efforts is a dysfunctional/exhausted state of CD8 T cells, which PD-1 monotherapy is not able to overcome. Recent studies have highlighted that PD-1
    MeSH term(s) Humans ; Programmed Cell Death 1 Receptor/metabolism ; Interleukin-2/pharmacology ; Interleukin-2/therapeutic use ; Interleukin-2/metabolism ; CD8-Positive T-Lymphocytes ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Cell Differentiation
    Chemical Substances Programmed Cell Death 1 Receptor ; Interleukin-2
    Language English
    Publishing date 2023-12-20
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2852626-0
    ISSN 2405-8025 ; 2405-8033 ; 2405-8033
    ISSN (online) 2405-8025 ; 2405-8033
    ISSN 2405-8033
    DOI 10.1016/j.trecan.2023.11.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Lung-MAP: A Collaborative Roadmap to Improve Cancer Outcomes.

    Leal, Ticiana A / Dahlberg, Suzanne E / Ramalingam, Suresh S

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2022  Volume 40, Issue 21, Page(s) 2285–2287

    MeSH term(s) Humans ; Lung ; Neoplasms
    Language English
    Publishing date 2022-06-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.22.01035
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Advances in Immunotherapy and Implications for Current Practice in Non-Small-Cell Lung Cancer.

    Steuer, Conor E / Ramalingam, Suresh S

    JCO oncology practice

    2021  Volume 17, Issue 11, Page(s) 662–668

    Abstract: Treatment options for patients with non-small-cell lung cancer (NSCLC) have improved dramatically in recent years. For decades, harnessing a person's own immune system to fight cancer has been a major area of research in oncology. Recently, these efforts ...

    Abstract Treatment options for patients with non-small-cell lung cancer (NSCLC) have improved dramatically in recent years. For decades, harnessing a person's own immune system to fight cancer has been a major area of research in oncology. Recently, these efforts have proven successful with the development of immune checkpoint inhibitors; these agents have now become part of the routine care of NSCLC. Presently, five programmed cell death-1 and programmed cell death-1 ligand 1 inhibitors and one anti-cytotoxic T-cell lymphocyte-4 inhibitor are US Food and Drug Administration-approved in the treatment of NSCLC. These drugs have made a dramatic difference in the lives of patients with NSCLC, although durable benefits are limited to a subset of patients. In this review, we highlight the trials that led to our current treatment practices, discuss areas of active research, and address common clinical issues that have risen as immune therapy has become a mainstay of treatment in NSCLC.
    MeSH term(s) Carcinoma, Non-Small-Cell Lung/drug therapy ; Humans ; Immunotherapy ; Lung Neoplasms/drug therapy ; Programmed Cell Death 1 Receptor
    Chemical Substances Programmed Cell Death 1 Receptor
    Language English
    Publishing date 2021-06-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 3028198-2
    ISSN 2688-1535 ; 2688-1527
    ISSN (online) 2688-1535
    ISSN 2688-1527
    DOI 10.1200/OP.21.00305
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: EGFR tyrosine kinase inhibitors (TKIs) for adjuvant therapy of early-stage non-small cell lung cancer (NSCLC): ready for the clinic?

    Steuer, Conor E / Ramalingam, Suresh S

    Translational lung cancer research

    2020  Volume 9, Issue 5, Page(s) 1720–1723

    Language English
    Publishing date 2020-11-04
    Publishing country China
    Document type Editorial ; Comment
    ZDB-ID 2754335-3
    ISSN 2226-4477 ; 2218-6751
    ISSN (online) 2226-4477
    ISSN 2218-6751
    DOI 10.21037/tlcr-2020-13
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Nivolumab plus Ipilimumab in Non-Small-Cell Lung Cancer. Reply.

    Hellmann, Matthew D / Ramalingam, Suresh S

    The New England journal of medicine

    2020  Volume 382, Issue 9, Page(s) 875

    MeSH term(s) Antineoplastic Combined Chemotherapy Protocols ; Carcinoma, Non-Small-Cell Lung ; Humans ; Ipilimumab ; Lung Neoplasms ; Nivolumab
    Chemical Substances Ipilimumab ; Nivolumab (31YO63LBSN)
    Language English
    Publishing date 2020-02-26
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc1916859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Osimertinib in EGFR-Mutated Advanced NSCLC. Reply.

    Ramalingam, Suresh S / Soria, Jean-Charles

    The New England journal of medicine

    2020  Volume 382, Issue 19, Page(s) 1864–1865

    MeSH term(s) Acrylamides ; Aniline Compounds ; Carcinoma, Non-Small-Cell Lung ; ErbB Receptors ; Humans ; Lung Neoplasms
    Chemical Substances Acrylamides ; Aniline Compounds ; osimertinib (3C06JJ0Z2O) ; EGFR protein, human (EC 2.7.10.1) ; ErbB Receptors (EC 2.7.10.1)
    Language English
    Publishing date 2020-07-18
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2001514
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Reply to N. Hanna et al and L. Xie et al.

    Ramalingam, Suresh S / Dahlberg, Suzanne E

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology

    2020  Volume 38, Issue 7, Page(s) 771–772

    MeSH term(s) Bevacizumab ; Carcinoma, Non-Small-Cell Lung ; Humans ; Lung Neoplasms ; Pemetrexed
    Chemical Substances Pemetrexed (04Q9AIZ7NO) ; Bevacizumab (2S9ZZM9Q9V)
    Language English
    Publishing date 2020-01-02
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604914-x
    ISSN 1527-7755 ; 0732-183X
    ISSN (online) 1527-7755
    ISSN 0732-183X
    DOI 10.1200/JCO.19.02741
    Database MEDical Literature Analysis and Retrieval System OnLINE

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