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  1. Book: Optimierung kardiomyozytärer Umbauprozesse durch Aktivierung gezielter Signalkaskaden

    Petersen, Antonia

    (Edition Scientifique)

    2020  

    Abstract: Adulte ventrikuläre Ratten-Kardiomyozyten lassen sich isolieren und unter FCS-haltigen Bedingungen über einen längeren Zeitraum kultivieren. Hierbei lässt sich ein Anpassungsprozess beobachten, der mit der Degradation des kontraktilen Apparats und dem ... ...

    Series title Edition Scientifique
    Abstract Adulte ventrikuläre Ratten-Kardiomyozyten lassen sich isolieren und unter FCS-haltigen Bedingungen über einen längeren Zeitraum kultivieren. Hierbei lässt sich ein Anpassungsprozess beobachten, der mit der Degradation des kontraktilen Apparats und dem morphologischen Abrunden der Kardiomyozyten beginnt. Im weiteren Verlauf kommt es zur Reorganisation des kontraktilen Apparats und zur Ausbildung von Pseu-dopodien. Die vorliegende Untersuchung widmet sich den ersten 48 Stunden in Kultur, die du...
    Keywords Uni ; Wissenschaft ; Doktorarbeit
    Language German
    Size 95 p.
    Publisher VVB Laufersweiler Verlag
    Document type Book
    Note Hochschulschriften Medizin
    Format 146 x 210
    ISBN 9783835969001 ; 3835969005
    Database PDA

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  2. Article ; Online: Chest computed tomography findings typical of COVID-19 pneumonia in Germany as early as 30 December 2019: a case report.

    Petersen, Antonia / Nagel, Sebastian / Hamm, Bernd / Taupitz, Matthias

    Journal of medical case reports

    2023  Volume 17, Issue 1, Page(s) 117

    Abstract: Background: The first cases of coronavirus disease 2019 were officially confirmed in Germany and its European neighbors in late January 2020. In France and Italy, there is evidence that coronavirus disease 2019 was spreading as early as December 2019.!## ...

    Abstract Background: The first cases of coronavirus disease 2019 were officially confirmed in Germany and its European neighbors in late January 2020. In France and Italy, there is evidence that coronavirus disease 2019 was spreading as early as December 2019.
    Case presentation: We report on a 71-year-old male patient from Germany who was admitted to our hospital on 30 December 2019 with pneumonia of unclear etiology and chest computed tomography findings typical of COVID-19 pneumonia.
    Conclusion: This case may indicate that coronavirus disease 2019 was already spreading in Germany as early as December 2019.
    MeSH term(s) Male ; Humans ; Aged ; COVID-19/diagnostic imaging ; SARS-CoV-2 ; Tomography, X-Ray Computed ; Pneumonia/diagnostic imaging ; Germany
    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-023-03809-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chest computed tomography findings typical of COVID-19 pneumonia in Germany as early as 30 December 2019

    Antonia Petersen / Sebastian Nagel / Bernd Hamm / Matthias Taupitz

    Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-

    a case report

    2023  Volume 4

    Abstract: Abstract Background The first cases of coronavirus disease 2019 were officially confirmed in Germany and its European neighbors in late January 2020. In France and Italy, there is evidence that coronavirus disease 2019 was spreading as early as December ... ...

    Abstract Abstract Background The first cases of coronavirus disease 2019 were officially confirmed in Germany and its European neighbors in late January 2020. In France and Italy, there is evidence that coronavirus disease 2019 was spreading as early as December 2019. Case presentation We report on a 71-year-old male patient from Germany who was admitted to our hospital on 30 December 2019 with pneumonia of unclear etiology and chest computed tomography findings typical of COVID-19 pneumonia. Conclusion This case may indicate that coronavirus disease 2019 was already spreading in Germany as early as December 2019.
    Keywords COVID-19 ; Computed tomography ; Europe ; Germany ; 2019 ; Case report ; Medicine ; R
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: The influence of left bundle branch block on myocardial T1 mapping.

    Petersen, Antonia / Nagel, Sebastian Niko / Hamm, Bernd / Elgeti, Thomas / Schaafs, Lars-Arne

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 5379

    Abstract: Tissue characterisation using T1 mapping has become an established magnetic resonance imaging (MRI) technique to detect myocardial diseases. This retrospective study aimed to determine the influence of left bundle branch block (LBBB) on T1 mapping at 1.5  ...

    Abstract Tissue characterisation using T1 mapping has become an established magnetic resonance imaging (MRI) technique to detect myocardial diseases. This retrospective study aimed to determine the influence of left bundle branch block (LBBB) on T1 mapping at 1.5 T. Datasets of 36 patients with LBBB and 27 healthy controls with T1 mapping (Modified Look-Locker inversion-recovery (MOLLI), 5(3)3 sampling) were included. T1 relaxation times were determined on mid-cavity short-axis images. R
    MeSH term(s) Humans ; Bundle-Branch Block/diagnostic imaging ; Retrospective Studies ; Myocardium ; Artifacts ; Chromosome Inversion
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-55821-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Postnatale Ernährung bei sehr kleinen Frühgeborenen

    Petersen, Hanna / Nomayo, Antonia / Jochum, Frank

    Neonatologie Scan

    2022  Volume 11, Issue 01, Page(s) 65–80

    Keywords parenteral ; enteral ; Nährstoffbedarf ; Stillen ; Programmierungseffekte
    Language German
    Publishing date 2022-02-18
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ISSN 2194-5470 ; 2194-5462
    ISSN (online) 2194-5470
    ISSN 2194-5462
    DOI 10.1055/a-0877-2985
    Database Thieme publisher's database

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  6. Article ; Online: Correction: Otten et al. Safety and Suitability of an Infant Formula Manufactured from Extensively Hydrolysed Protein in Healthy Term Infants.

    Otten, Lindsey / Schelker, Elisabeth / Petersen, Hanna / Nomayo, Antonia / Fleddermann, Manja / Arendt, Bianca M / Britzl, Theresa / Haberl, Elisabeth M / Jochum, Frank

    Nutrients

    2023  Volume 15, Issue 20

    Abstract: In the original publication [ ... ]. ...

    Abstract In the original publication [...].
    Language English
    Publishing date 2023-10-12
    Publishing country Switzerland
    Document type Published Erratum
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15204347
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  7. Article ; Online: Safety and Suitability of an Infant Formula Manufactured from Extensively Hydrolysed Protein in Healthy Term Infants.

    Otten, Lindsey / Schelker, Elisabeth / Petersen, Hanna / Nomayo, Antonia / Fleddermann, Manja / Arendt, Bianca M / Britzl, Theresa / Haberl, Elisabeth M / Jochum, Frank

    Nutrients

    2023  Volume 15, Issue 8

    Abstract: We aimed to demonstrate that healthy term infants experience noninferior growth with infant formula manufactured from extensively hydrolysed whey protein (eHF) compared to intact cow's milk protein (control formula, CF). This prospective, randomised, ... ...

    Abstract We aimed to demonstrate that healthy term infants experience noninferior growth with infant formula manufactured from extensively hydrolysed whey protein (eHF) compared to intact cow's milk protein (control formula, CF). This prospective, randomised, double-blind, parallel-group, controlled, multicentre trial included healthy term infants who were exclusively formula-fed. Infants ≤ 25 days of age received eHF or CF for at least three months up to 120 days of age, with a follow-up until 180 days of age. A reference group included exclusively breastfed infants (BF). Of 318 infants randomised, 297 (148 CF, 149 eHF) completed the study per protocol. Weight gain up to 120 days of age was noninferior (margin -3.0 g/day) in eHF (28.95 (95% CI: 27.21; 30.68) g/day) compared to CF (28.85 (95% CI: 27.10; 30.61) g/day) with a difference in means of 0.09 g/day and a lower limit of the one-sided 97.5% CI of -0.86 g/day (
    MeSH term(s) Animals ; Female ; Cattle ; Infant Formula ; Prospective Studies ; Whey Proteins ; Weight Gain ; Double-Blind Method ; Milk Hypersensitivity
    Chemical Substances Whey Proteins
    Language English
    Publishing date 2023-04-14
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Multicenter Study ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15081901
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  8. Article: Cardiac magnetic resonance imaging in patients with left bundle branch block: Patterns of dyssynchrony and implications for late gadolinium enhancement imaging.

    Petersen, Antonia / Nagel, Sebastian Niko / Hamm, Bernd / Elgeti, Thomas / Schaafs, Lars-Arne

    Frontiers in cardiovascular medicine

    2022  Volume 9, Page(s) 977414

    Abstract: Background: Left bundle branch block (LBBB) is a ventricular conduction delay with high prevalence. Aim of our study is to identify possible recurring patterns of artefacts in late gadolinium enhancement (LGE) imaging in patients with LBBB who undergo ... ...

    Abstract Background: Left bundle branch block (LBBB) is a ventricular conduction delay with high prevalence. Aim of our study is to identify possible recurring patterns of artefacts in late gadolinium enhancement (LGE) imaging in patients with LBBB who undergo cardiac magnetic resonance imaging (MRI) and to define parameters of mechanical dyssynchrony associated with artefacts in LGE images.
    Materials and methods: Fifty-five patients with LBBB and 62 controls were retrospectively included. Inversion time (TI) scout and LGE images were reviewed for artefacts. Dyssynchrony was identified using cardiac MRI by determining left ventricular systolic dyssynchrony indices (global, septal segments, and free wall segments) derived from strain analysis and features of mechanical dyssynchrony (apical rocking and septal flash).
    Results: Thirty-seven patients (67%) with LBBB exhibited inhomogeneous myocardial nulling in TI scout images. Among them 25 (68%) patients also showed recurring artefact patterns in the septum or free wall on LGE images and artefacts also persisted in 18 (72%) of those cases when utilising phase sensitive inversion recovery. Only the systolic dyssynchrony index of septal segments allowed differentiation of patient subgroups (artefact/no artefact) and healthy controls (given as median, median ± interquartile range); LBBB with artefact: 10.44% (0.44-20.44%); LBBB without artefact: 6.82% (-2.18-15.83%); controls: 4.38% (1.38-7.38%);
    Conclusion: Patients with LBBB show recurring artefact patterns in LGE imaging. Use of strain analysis and evaluation of mechanical dyssynchrony may predict the occurrence of such artefacts already during the examination and counteract misinterpretation.
    Language English
    Publishing date 2022-10-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2022.977414
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  9. Article: A Care Concept of Community Health Nursing Interventions for Adults With Chronic Health Conditions in an Urban Area: Protocol for a Randomized Controlled Field Trial (CoSta Study).

    Nock, Annike Morgane / Iversen, Linda / Waidhas, Lukas / Zapf, Antonia / Seifert, Caroline / Petersen-Ewert, Corinna

    JMIR research protocols

    2022  Volume 11, Issue 9, Page(s) e37965

    Abstract: Background: Implementing community health nursing programs is a new field of application in the primary health sector of Germany. Hence, there is limited evidence of effective community-based and nurse-led interventions with regard to the German health ... ...

    Abstract Background: Implementing community health nursing programs is a new field of application in the primary health sector of Germany. Hence, there is limited evidence of effective community-based and nurse-led interventions with regard to the German health care system. International research findings are mostly not transferable. The Community Health Nursing in der Stadt (CoSta; ie, "Community Health Nursing in the City") project is the first study that examines a community health nurse-led intervention for adults with chronic health conditions.
    Objective: This study protocol describes the design and methods of a randomized controlled field trial that will investigate if a community health nurse-based intervention has an impact on health-related quality of life in adults with chronic conditions.
    Methods: The study was designed as a randomized controlled trial that will be conducted under real-life conditions in the field. In a 4-month period, patients with at least 1 chronic International Classification of Diseases, Tenth Revision, diagnosis will be enrolled. Participants will be randomly allocated to an intervention group or a control group. The sample size was assumed based on an effect size of 0.50 with a significance level of .05, using a 2-sided (2-tailed), 2-sample unequal variance t test. The control group will be treated as usual. The intervention group will receive-in addition to the usual treatment-preventive home visits; consultations; and educative training, which will be offered by 2 community health nurses for up to 12 months. Both groups will be followed up at baseline, after 6 months, and after 12 months. The primary outcome measure is the mental component summary score from the 36-Item Short Form Health Survey after 12-months. Secondary patient outcomes will be included. The study received ethics approval from the Competence Health Center's institutional review board at the University of Applied Sciences Hamburg (procedure number: 2020-14).
    Results: The CoSta project was funded by the Federal Ministry of Education and Research Germany (contract number: 13FH019SX8). In total, 187 participants were recruited at the beginning of August 2021. Further, 92 were excluded and 94 were randomized. Data collection will be conducted until the end of 2022.
    Conclusions: Our study will provide data with regard to the effectiveness of community nurse-led interventions that focus on the treatment of vulnerable adults with chronic health conditions in a community health center. In secondary analyses, the associations among influencing social factors (education, income, and employment) will be examined. We expect results that will help reduce the research-to-practice gap.
    Trial registration: German Clinical Trials Register DRKS00026164; https://tinyurl.com/yckxc5ut.
    International registered report identifier (irrid): DERR1-10.2196/37965.
    Language English
    Publishing date 2022-09-28
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2719222-2
    ISSN 1929-0748
    ISSN 1929-0748
    DOI 10.2196/37965
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Gastrointestinal Tolerance of an Infant Formula Manufactured from Extensively Hydrolysed Protein in Healthy Term Infants.

    Otten, Lindsey / Schelker, Elisabeth / Petersen, Hanna / Nomayo, Antonia / Conzade, Romy / Günther, Julia / Grieger, Andrea / Jochum, Frank / On Behalf Of The Hasi Study Group

    Nutrients

    2023  Volume 15, Issue 21

    Abstract: The evaluation of secondary parameters of a prospective, randomised, controlled, multicentre intervention trial aimed to analyse gastrointestinal tolerance of an infant formula manufactured from extensively hydrolysed whey protein (eHF) compared to ... ...

    Abstract The evaluation of secondary parameters of a prospective, randomised, controlled, multicentre intervention trial aimed to analyse gastrointestinal tolerance of an infant formula manufactured from extensively hydrolysed whey protein (eHF) compared to intact cow's milk protein (control formula, CF) in healthy term infants. Infants ≤ 25 days of age, who were exclusively formula-fed, were randomised to receive eHF or CF for at least three months up to 120 days of age. An exclusively breastfed reference group (BF) was included for descriptive comparison. Infants' gastrointestinal tolerance was evaluated based on stool parameters, the Amsterdam Infant Stool Scale (AISS), the Infant Gastrointestinal Symptom Questionnaire (IGSQ), and sleeping patterns. Of 359 infants included, 297 randomised (eHF:
    MeSH term(s) Animals ; Female ; Cattle ; Infant ; Humans ; Infant Formula/analysis ; Prospective Studies ; Breast Feeding ; Whey Proteins ; Feces ; Gastrointestinal Diseases ; Milk Hypersensitivity
    Chemical Substances Whey Proteins
    Language English
    Publishing date 2023-11-04
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Multicenter Study ; Journal Article
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu15214674
    Database MEDical Literature Analysis and Retrieval System OnLINE

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