LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 69

Search options

  1. Article ; Online: Direct oral Xa inhibitors for the treatment of venous thromboembolism after bariatric surgery.

    Kushnir, Margarita / Gali, Radhika / Alexander, Mariam / Billett, Henny H

    Blood advances

    2022  Volume 7, Issue 2, Page(s) 224–226

    MeSH term(s) Humans ; Venous Thromboembolism/drug therapy ; Venous Thromboembolism/etiology ; Anticoagulants/therapeutic use ; Rivaroxaban ; Bariatric Surgery/adverse effects
    Chemical Substances Anticoagulants ; Rivaroxaban (9NDF7JZ4M3)
    Language English
    Publishing date 2022-05-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2915908-8
    ISSN 2473-9537 ; 2473-9529
    ISSN (online) 2473-9537
    ISSN 2473-9529
    DOI 10.1182/bloodadvances.2021006696
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 7153: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article: Repetitive nonreentrant ventriculoatrial synchrony inducing atrial fibrillation in setting of dofetilide.

    Garber, Leonid / Shulman, Eric / Kushnir, Alexander / Saraon, Tajinderpal / Park, David S / Chinitz, Larry A

    HeartRhythm case reports

    2022  Volume 8, Issue 5, Page(s) 320–324

    Language English
    Publishing date 2022-02-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2022.01.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Biochemical Dymorphism of Potassium Content and its Adaptive Significance in Domestic Reindeer

    Yuzhakov Alexander / Kushnir Anatoly / Laishev Kasim / Zabrodin Vasily

    E3S Web of Conferences, Vol 285, p

    2021  Volume 03005

    Abstract: The connection between the types of potassium concentration and the ecogenesis of the studied groups of animals, with the degree of extreme conditions of breeding, with types of potassium in extreme conditions of breeding is known. In this regard, ... ...

    Abstract The connection between the types of potassium concentration and the ecogenesis of the studied groups of animals, with the degree of extreme conditions of breeding, with types of potassium in extreme conditions of breeding is known. In this regard, studies on autochthonous species of ungulates in the Subarctic are of great interest, the most numerous of which is the reindeer (Rangifer tarandus). Comparative analysis of the adaptive responses of NK and LK types at different levels of organization confirmed the presence of the adaptive advantage of animals characterized by a hereditarily high concentration of potassium in the blood in ecological-geographical zones with extreme environmental conditions. As a result of a study on domesticated reindeer, a clearly expressed dimorphism in the level of potassium in the blood was revealed, due to a genetically controlled high NK and low LK concentration. The average level of potassium in whole blood in the studied population of reindeer is 26.94 ± 0.56 meq/l with a variability of 24.61%. It was revealed that the average level of potassium content in whole blood by sex and age was distributed as follows: whales 22.97 - 25.80 meq/l at P> 0.05, castrate bulls had indicators significantly higher than 28.37 - 29.58 meq / l, at P> 0.05, the young showed intermediate indicators - 27.37 - 28.13 at P> 0.05. The intragroup variability in potassium content in whole blood ranged from 15.5 to 31.05%. It was found that in domestic reindeer the ratio of animals of the high-potassium (HK) type is 88.02% and of the lowpotassium (LK) type - 11.98%, while the gene frequencies for highpotassium animals are 0.9381.
    Keywords Environmental sciences ; GE1-350
    Subject code 630
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Determination of phenols in natural and waste waters by capillary electrophoresis after preconcentration on magnetic nanoparticles coated with aminated hypercrosslinked polystyrene.

    Gubin, Alexander / Sukhanov, Pavel / Kushnir, Aleksei / Sannikova, Natalia / Konopleva, Victoria / Nikulina, Alla

    Journal of separation science

    2021  Volume 44, Issue 9, Page(s) 1978–1988

    Abstract: An efficient sorbent for magnetic solid-phase extraction was developed from ... ...

    Abstract An efficient sorbent for magnetic solid-phase extraction was developed from Fe
    Language English
    Publishing date 2021-03-13
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2047990-6
    ISSN 1615-9314 ; 1615-9306
    ISSN (online) 1615-9314
    ISSN 1615-9306
    DOI 10.1002/jssc.202001177
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Ryanodine receptor dysfunction in human disorders.

    Kushnir, Alexander / Wajsberg, Benjamin / Marks, Andrew R

    Biochimica et biophysica acta. Molecular cell research

    2018  Volume 1865, Issue 11 Pt B, Page(s) 1687–1697

    Abstract: Regulation of intracellular calcium ( ... ...

    Abstract Regulation of intracellular calcium (Ca
    MeSH term(s) Animals ; Calcium/metabolism ; Calcium Signaling/drug effects ; Calmodulin/metabolism ; Carrier Proteins/metabolism ; Disease Susceptibility ; Endoplasmic Reticulum/metabolism ; Humans ; Ion Channel Gating/drug effects ; Ligands ; Phosphorylation ; Protein Binding ; Ryanodine Receptor Calcium Release Channel/chemistry ; Ryanodine Receptor Calcium Release Channel/genetics ; Ryanodine Receptor Calcium Release Channel/metabolism
    Chemical Substances Calmodulin ; Carrier Proteins ; Ligands ; Ryanodine Receptor Calcium Release Channel ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2018-07-21
    Publishing country Netherlands
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 60-7
    ISSN 1879-2596 ; 1879-260X ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 1879-2650 ; 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    ISSN (online) 1879-2596 ; 1879-260X ; 1872-8006 ; 1879-2642 ; 1879-2618 ; 1879-2650
    ISSN 0006-3002 ; 0005-2728 ; 0005-2736 ; 0304-4165 ; 0167-4838 ; 1388-1981 ; 0167-4889 ; 0167-4781 ; 0304-419X ; 1570-9639 ; 0925-4439 ; 1874-9399
    DOI 10.1016/j.bbamcr.2018.07.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uc I Zs.247: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: High-density substrate and activation mapping of epicardial ventricular tachycardia during left ventricular assist device implant.

    Kushnir, Alexander / Pallister, Kristin H / Chaudhary, Salma B / Cevasco, Marisa / Naka, Yoshifumi / Saluja, Deepak

    HeartRhythm case reports

    2020  Volume 6, Issue 10, Page(s) 690–693

    Language English
    Publishing date 2020-07-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2020.06.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: Structural plasticity of axon initial segment in spinal cord neurons underlies inflammatory pain.

    Caspi, Yaki / Mazar, Michael / Kushnir, Yishai / Mazor, Yoav / Katz, Ben / Lev, Shaya / Binshtok, Alexander M

    Pain

    2022  Volume 164, Issue 6, Page(s) 1388–1401

    Abstract: Abstract: Physiological or pathology-mediated changes in neuronal activity trigger structural plasticity of the action potential generation site-the axon initial segment (AIS). These changes affect intrinsic neuronal excitability, thus tuning neuronal ... ...

    Abstract Abstract: Physiological or pathology-mediated changes in neuronal activity trigger structural plasticity of the action potential generation site-the axon initial segment (AIS). These changes affect intrinsic neuronal excitability, thus tuning neuronal and overall network output. Using behavioral, immunohistochemical, electrophysiological, and computational approaches, we characterized inflammation-related AIS plasticity in rat's superficial (lamina II) spinal cord dorsal horn (SDH) neurons and established how AIS plasticity regulates the activity of SDH neurons, thus contributing to pain hypersensitivity. We show that in naive conditions, AIS in SDH inhibitory neurons is located closer to the soma than in excitatory neurons. Shortly after inducing inflammation, when the inflammatory hyperalgesia is at its peak, AIS in inhibitory neurons is shifted distally away from the soma. The shift in AIS location is accompanied by the decrease in excitability of SDH inhibitory neurons. These AIS location and excitability changes are selective for inhibitory neurons and reversible. We show that AIS shift back close to the soma, and SDH inhibitory neurons' excitability increases to baseline levels following recovery from inflammatory hyperalgesia. The computational model of SDH inhibitory neurons predicts that the distal shift of AIS is sufficient to decrease the intrinsic excitability of these neurons. Our results provide evidence of inflammatory pain-mediated AIS plasticity in the central nervous system, which differentially affects the excitability of inhibitory SDH neurons and contributes to inflammatory hyperalgesia.
    MeSH term(s) Animals ; Rats ; Axon Initial Segment/physiology ; Hyperalgesia ; Neurons/physiology ; Pain ; Inflammation ; Spinal Cord ; Neuronal Plasticity/physiology
    Language English
    Publishing date 2022-11-29
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 193153-2
    ISSN 1872-6623 ; 0304-3959
    ISSN (online) 1872-6623
    ISSN 0304-3959
    DOI 10.1097/j.pain.0000000000002829
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1158: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Reply to 'Mechanisms of ryanodine receptor 2 dysfunction in heart failure'.

    Dridi, Haikel / Kushnir, Alexander / Zalk, Ran / Yuan, Qi / Melville, Zephan / Marks, Andrew R

    Nature reviews. Cardiology

    2020  Volume 17, Issue 11, Page(s) 749–750

    MeSH term(s) Atrial Fibrillation ; Calcium ; Heart Failure ; Humans ; Ryanodine Receptor Calcium Release Channel
    Chemical Substances Ryanodine Receptor Calcium Release Channel ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2020-09-07
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2490375-9
    ISSN 1759-5010 ; 1759-5002
    ISSN (online) 1759-5010
    ISSN 1759-5002
    DOI 10.1038/s41569-020-00444-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6019: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 98: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: Ionic-liquid-modified magnetite nanoparticles for MSPE-GC-MS determination of 2,4-D butyl ester and its metabolites in water, soil, and bottom sediments

    Gubin, Alexander / Sukhanov, Pavel / Kushnir, Aleksei / Shikhaliev, Khidmet / Potapov, Mikhail / Kovaleva, Elena

    Environmental nanotechnology, monitoring & management. 2022 May, v. 17

    2022  

    Abstract: Efficient sorbents based on magnetite nanoparticles and ionic liquids are proposed for solid-phase extraction of the pesticide, butyl 2,4-dichlorophenoxyacetate (2,4-DB), and its metabolites, 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4-dichlorophenol (2, ... ...

    Abstract Efficient sorbents based on magnetite nanoparticles and ionic liquids are proposed for solid-phase extraction of the pesticide, butyl 2,4-dichlorophenoxyacetate (2,4-DB), and its metabolites, 2,4-dichlorophenoxyacetic acid (2,4-D), 2,4-dichlorophenol (2,4-DCP), and 4-chlorophenol (4-CP). Fe₃O₄ nanoparticles were modified with 1-carboxymethyl-3-methylimidazolium chloride, 1,3-dimethylimidazolium-2-carboxylate, and 1,3-dimethylimidazolium-2-carboxylate. The obtained sorbents possess a saturation magnetization of 29–37 emu/g and a specific surface area of 89.7–119.5 m²g⁻¹. The highest extraction efficiency was achieved for the sorbent modified with 1,3-dimethylimidazolium-2-carboxylate. Upon single extraction (the sorbent weight was 0.02 g, pH 4–5, t = 20 min), 98–99% of 2,4-D and 2,4-DB, 92% of 2,4-DCP, and 94% of 4-CP were extracted. The enrichment factor after desorption reached 1602–1710. The limit equilibrium sorption was 303.1–520.8 mg g⁻¹. The combination of MSPE with GC-MS was used to monitor the pollution of soils, ground and river waters, and bottom sediments by 2,4-DB and its metabolites. Also, the distribution of the pesticide and its metabolites over the profile of typical and residual-calcareous chernozems up to a depth of 110 cm was studied. The limits of detection of 2,4-D and 2,4-DB were 0.1 ngL⁻¹ upon determination in distilled water, 0.5–0.6 ngL⁻¹ in river and ground waters, 10 ng kg⁻¹ in soil, and 25–30 ng kg⁻¹ in bottom sediments. The limits of detection of 4-CP and 2,4-DCP were slightly lower to be 5 ngL⁻¹ in distilled water and 8–10 ngL⁻¹ in river and ground waters. Upon determination in complex matrices, such as soils, the limits of detection of 4-CP and 2,4-DCP were 10–15 ng kg⁻¹.
    Keywords 2,4-D ; 2,4-DB ; 2,4-dichlorophenol ; 4-chlorophenol ; Chernozems ; administrative management ; chlorides ; desorption ; magnetite ; metabolites ; pH ; rivers ; solid phase extraction ; sorbents ; sorption ; surface area
    Language English
    Dates of publication 2022-05
    Publishing place Elsevier B.V.
    Document type Article
    ZDB-ID 2821777-9
    ISSN 2215-1532
    ISSN 2215-1532
    DOI 10.1016/j.enmm.2022.100652
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: Comparison of combined substrate-based mapping techniques to identify critical sites for ventricular tachycardia ablation.

    Khan, Hassan / Bonvissuto, Matthew R / Rosinski, Elizabeth / Shokr, Mohamed / Metcalf, Kara / Jankelson, Lior / Kushnir, Alexander / Park, David S / Bernstein, Scott A / Spinelli, Michael A / Aizer, Anthony / Holmes, Douglas / Chinitz, Larry A / Barbhaiya, Chirag R

    Heart rhythm

    2023  Volume 20, Issue 6, Page(s) 808–814

    Abstract: Background: Established electroanatomic mapping techniques for substrate mapping for ventricular tachycardia (VT) ablation includes voltage mapping, isochronal late activation mapping (ILAM), and fractionation mapping. Omnipolar mapping (Abbott Medical, ...

    Abstract Background: Established electroanatomic mapping techniques for substrate mapping for ventricular tachycardia (VT) ablation includes voltage mapping, isochronal late activation mapping (ILAM), and fractionation mapping. Omnipolar mapping (Abbott Medical, Inc.) is a novel optimized bipolar electrogram creation technique with integrated local conduction velocity annotation. The relative utilities of these mapping techniques are unknown.
    Objective: The purpose of this study was to evaluate the relative utility of various substrate mapping techniques for the identification of critical sites for VT ablation.
    Methods: Electroanatomic substrate maps were created and retrospectively analyzed in 27 patients in whom 33 VT critical sites were identified.
    Results: Both abnormal bipolar voltage and omnipolar voltage encompassed all critical sites and were observed over a median of 66 cm
    Conclusion: ILAM, fractionation, and CV mapping each identified distinct critical sites and provided a smaller area of interest than did voltage mapping alone. The sensitivity of novel mapping modalities improved with greater local point density.
    MeSH term(s) Humans ; Tachycardia, Ventricular/diagnosis ; Tachycardia, Ventricular/surgery ; Retrospective Studies ; Electrophysiologic Techniques, Cardiac/methods ; Catheter Ablation/methods
    Language English
    Publishing date 2023-02-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2229357-7
    ISSN 1556-3871 ; 1547-5271
    ISSN (online) 1556-3871
    ISSN 1547-5271
    DOI 10.1016/j.hrthm.2023.02.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6278: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top