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  1. Article: National Institutes of Health discover naturopathic principle.

    Lamson, Davis W

    Alternative medicine review : a journal of clinical therapeutic

    2010  Volume 15, Issue 3, Page(s) 186

    MeSH term(s) Humans ; Immunity ; Integrative Medicine/organization & administration ; Methicillin-Resistant Staphylococcus aureus ; National Institutes of Health (U.S.)/organization & administration ; Naturopathy ; Staphylococcal Infections/therapy ; United States
    Language English
    Publishing date 2010-09
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The roles of complementary medicine in oncology.

    Lamson, Davis W

    Alternative medicine review : a journal of clinical therapeutic

    2007  Volume 12, Issue 4, Page(s) 313–318

    MeSH term(s) Antineoplastic Agents/therapeutic use ; Complementary Therapies ; Humans ; Neoplasm Recurrence, Local/prevention & control ; Neoplasms/therapy ; Remission Induction ; Research Support as Topic
    Chemical Substances Antineoplastic Agents
    Language English
    Publishing date 2007-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Immune-modifying and antimicrobial effects of Eucalyptus oil and simple inhalation devices.

    Sadlon, Angela E / Lamson, Davis W

    Alternative medicine review : a journal of clinical therapeutic

    2010  Volume 15, Issue 1, Page(s) 33–47

    Abstract: Eucalyptus oil (EO) and its major component, 1,8-cineole, have antimicrobial effects against many bacteria, including Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus (MRSA), viruses, and fungi (including Candida). Surprisingly ... ...

    Abstract Eucalyptus oil (EO) and its major component, 1,8-cineole, have antimicrobial effects against many bacteria, including Mycobacterium tuberculosis and methicillin-resistant Staphylococcus aureus (MRSA), viruses, and fungi (including Candida). Surprisingly for an antimicrobial substance, there are also immune-stimulatory, anti-inflammatory, antioxidant, analgesic, and spasmolytic effects. Of the white blood cells, monocytes and macrophages are most affected, especially with increased phagocytic activity. Application by either vapor inhalation or oral route provides benefit for both purulent and non-purulent respiratory problems, such as bronchitis, asthma, and chronic obstructive pulmonary disease (COPD). There is a long history of folk usage with a good safety record. More recently, the biochemical details behind these effects have been clarified. Although other plant oils may be more microbiologically active, the safety of moderate doses of EO and its broad-spectrum antimicrobial action make it an attractive alternative to pharmaceuticals. EO has also been shown to offset the myelotoxicity of one chemotherapy agent. Whether this is a general attribute that does not decrease the benefit of chemotherapy remains to be determined. This article also provides instruction on how to assemble inexpensive devices for vapor inhalation.
    MeSH term(s) Administration, Inhalation ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/pharmacology ; Asthma/drug therapy ; Bronchitis/drug therapy ; Eucalyptus ; Gram-Negative Bacteria/drug effects ; Gram-Positive Bacteria/drug effects ; Humans ; Immunity/drug effects ; Lymphocyte Activation/drug effects ; Monoterpenes/administration & dosage ; Monoterpenes/pharmacology ; Oils, Volatile/administration & dosage ; Oils, Volatile/pharmacology ; Pulmonary Disease, Chronic Obstructive/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Eucalyptus terpene oil ; Monoterpenes ; Oils, Volatile
    Language English
    Publishing date 2010-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A case of MRSA controlled: predisposing factors and immune stimulation.

    Lamson, Davis W / Sadlon, Angela E

    Alternative medicine review : a journal of clinical therapeutic

    2010  Volume 15, Issue 2, Page(s) 147–151

    Abstract: Most treatments for methicillin-resistant Staphylococcus aureus (MRSA) focus on agents to eliminate the bacterium. Since MRSA infection is not universal, susceptibility factors are possible. Immune resistance could be lowered in such individuals; ... ...

    Abstract Most treatments for methicillin-resistant Staphylococcus aureus (MRSA) focus on agents to eliminate the bacterium. Since MRSA infection is not universal, susceptibility factors are possible. Immune resistance could be lowered in such individuals; therefore, locating immune-inhibiting or immune-enhancing factors might decrease susceptibility. Such seemed to be the case in a 48-year-old female who presented with recurring MRSA despite multiple rounds of a variety of antibiotics. When the patient encountered an intensely stressful situation an outbreak of MRSA occurred. The patient had additional underlying health issues that suppressed her immune system and made her more susceptible to stress. Gluten allergy and hypothyroidism were discovered and alleviated but did not end the MRSA outbreaks. Implementation of a popular treatment from the 1930s, intravenous dilute hydrochloric acid (for immune stimulation), prevented most MRSA outbreaks when administered frequently. This case provides anecdotal support for the proposition that immune enhancement is a viable approach to forestall or clear recurring MRSA.
    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Female ; Humans ; Hydrochloric Acid/administration & dosage ; Immunity/drug effects ; Methicillin-Resistant Staphylococcus aureus/drug effects ; Middle Aged ; Staphylococcal Infections/drug therapy ; Staphylococcal Infections/physiopathology
    Chemical Substances Anti-Bacterial Agents ; Hydrochloric Acid (QTT17582CB)
    Language English
    Publishing date 2010-07
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Vitamin K2 in bone metabolism and osteoporosis.

    Plaza, Steven M / Lamson, Davis W

    Alternative medicine review : a journal of clinical therapeutic

    2005  Volume 10, Issue 1, Page(s) 24–35

    Abstract: This article covers in vitro, in vivo, and human data on the positive effect of vitamin K2 on osteoporosis. Data is available on vitamin K2 for osteoporosis caused by a number of conditions, including postmenopausal osteoporosis, Parkinson's disease, ... ...

    Abstract This article covers in vitro, in vivo, and human data on the positive effect of vitamin K2 on osteoporosis. Data is available on vitamin K2 for osteoporosis caused by a number of conditions, including postmenopausal osteoporosis, Parkinson's disease, biliary cirrhosis, stroke, and drug-induced osteoporosis. The activity of vitamin K2 involves both an increase in the bone-building process and a separate decrease in the bone-loss process. Vitamin K2 exerts a more powerful influence on bone than vitamin K1, and should be considered for prevention or treatment in those conditions known to contribute to osteoporosis.
    MeSH term(s) Animals ; Bone Diseases, Metabolic/etiology ; Bone Diseases, Metabolic/prevention & control ; Disease Models, Animal ; Humans ; Osteoporosis/drug therapy ; Osteoporosis/prevention & control ; Vitamin K 2/metabolism ; Vitamin K 2/therapeutic use
    Chemical Substances Vitamin K 2 (11032-49-8)
    Language English
    Publishing date 2005-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: A case of early renal functional impairment resolved with nutrients and botanicals.

    Lamson, Davis W / Wright, Jonathan V

    Alternative medicine review : a journal of clinical therapeutic

    2003  Volume 8, Issue 1, Page(s) 55–58

    Abstract: The use of three herbal/nutritional products over a period of two months normalized blood urea nitrogen (BUN), serum creatinine, and creatinine clearance in a case of early functional kidney impairment. Although previous use of intravenous EDTA resolved ... ...

    Abstract The use of three herbal/nutritional products over a period of two months normalized blood urea nitrogen (BUN), serum creatinine, and creatinine clearance in a case of early functional kidney impairment. Although previous use of intravenous EDTA resolved Raynaud's syndrome symptoms, it provided little improvement to abnormal creatinine clearance.
    MeSH term(s) Aged ; Aged, 80 and over ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Blood Urea Nitrogen ; Bromelains/therapeutic use ; Chelation Therapy/methods ; Chitin/therapeutic use ; Creatinine/metabolism ; Drugs, Chinese Herbal/therapeutic use ; Edetic Acid/therapeutic use ; Humans ; Male ; Medicine, Ayurvedic ; Phytotherapy/methods ; Plant Preparations/therapeutic use ; Raynaud Disease/therapy ; Renal Insufficiency/metabolism ; Renal Insufficiency/therapy
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Drugs, Chinese Herbal ; Plant Preparations ; Chitin (1398-61-4) ; Bromelains (9001-00-7) ; Edetic Acid (9G34HU7RV0) ; Creatinine (AYI8EX34EU)
    Language English
    Publishing date 2003-02
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The anticancer effects of vitamin K.

    Lamson, Davis W / Plaza, Steven M

    Alternative medicine review : a journal of clinical therapeutic

    2003  Volume 8, Issue 3, Page(s) 303–318

    Abstract: Vitamin K, an essential nutrient often associated with the clotting cascade, has been the focus of considerable research demonstrating an anticancer potential. Much of this research has focused on vitamin K3, although vitamins K2 and K1 have also been ... ...

    Abstract Vitamin K, an essential nutrient often associated with the clotting cascade, has been the focus of considerable research demonstrating an anticancer potential. Much of this research has focused on vitamin K3, although vitamins K2 and K1 have also been shown to have anticancer effects. Early studies of vitamin K3 employed an oxidative model to explain the anticancer effects seen in both in vitro and in vivo studies; however, this model does not adequately address the action of vitamins K1 and K2. Recent research has demonstrated the anticancer action of vitamin K may act at the level of tyrosine kinases and phosphatases, modulating various transcription factors such as Myc and Fos. Tyrosine kinases associated with cyclins have also been shown to be affected by vitamin K, which can lead to cell cycle arrest and cell death.
    MeSH term(s) Animals ; Anticarcinogenic Agents/therapeutic use ; Cell Cycle/drug effects ; Humans ; Mice ; Neoplasms/prevention & control ; Rats ; Transcription Factors/drug effects ; Vitamin K/physiology ; Vitamin K/therapeutic use ; Vitamin K 1/therapeutic use ; Vitamin K 2/therapeutic use ; Vitamin K 3/therapeutic use
    Chemical Substances Anticarcinogenic Agents ; Transcription Factors ; Vitamin K 2 (11032-49-8) ; Vitamin K (12001-79-5) ; Vitamin K 3 (723JX6CXY5) ; Vitamin K 1 (84-80-0)
    Language English
    Publishing date 2003-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Mitochondrial factors in the pathogenesis of diabetes: a hypothesis for treatment.

    Lamson, Davis W / Plaza, Steven M

    Alternative medicine review : a journal of clinical therapeutic

    2002  Volume 7, Issue 2, Page(s) 94–111

    Abstract: A growing body of evidence has demonstrated a link between various disturbances in mitochondrial functioning and type 2 diabetes. This review focuses on a range of mitochondrial factors important in the pathogenesis of this disease. The mitochondrion is ... ...

    Abstract A growing body of evidence has demonstrated a link between various disturbances in mitochondrial functioning and type 2 diabetes. This review focuses on a range of mitochondrial factors important in the pathogenesis of this disease. The mitochondrion is an integral part of the insulin system found in the islet cells of the pancreas. Because of the systemic complexity of mitochondrial functioning in terms of tissue and energetic thresholds, details of structure and function are reviewed. The expression of type 2 diabetes can be ascribed to a number of qualitative or quantitative changes in the mitochondria. Qualitative changes refer to genetic disturbances in mitochondrial DNA (mtDNA). Heteroplasmic as well as homoplasmic mutations of mtDNA can lead to the development of a number of genetic disorders that express the phenotype of type 2 diabetes. Quantitative decreases in mtDNA copy number have also been linked to the pathogenesis of diabetes. The study of the relationship of mtDNA to type 2 diabetes has revealed the influence of the mitochondria on nuclear-encoded glucose transporters and the influence of nuclear encoded uncoupling proteins on the mitochondria. This basic research into the pathogenesis of diabetes has led to the awareness of natural therapeutics (such as coenzyme Q10) that increase mitochondrial functioning and avoidance of trans-fatty acids that decrease mitochondrial functioning.
    MeSH term(s) Adenosine Triphosphate/metabolism ; Animals ; Carrier Proteins/physiology ; Coenzymes ; DNA, Mitochondrial/genetics ; Diabetes Mellitus, Type 2/etiology ; Diabetes Mellitus, Type 2/therapy ; Dietary Fats/adverse effects ; Glucose/metabolism ; Humans ; Insulin/metabolism ; Ion Channels ; Membrane Proteins/physiology ; Mitochondria/physiology ; Mitochondrial Proteins ; Mutation ; Rats ; Ubiquinone/analogs & derivatives ; Ubiquinone/therapeutic use ; Uncoupling Protein 1
    Chemical Substances Carrier Proteins ; Coenzymes ; DNA, Mitochondrial ; Dietary Fats ; Insulin ; Ion Channels ; Membrane Proteins ; Mitochondrial Proteins ; Uncoupling Protein 1 ; Ubiquinone (1339-63-5) ; Adenosine Triphosphate (8L70Q75FXE) ; coenzyme Q10 (EJ27X76M46) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2002-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: The safety and efficacy of high-dose chromium.

    Lamson, Davis W / Plaza, Steven M

    Alternative medicine review : a journal of clinical therapeutic

    2002  Volume 7, Issue 3, Page(s) 218–235

    Abstract: The data on the standards for chromium requirements and the safety of various chromium compounds and doses are reviewed. The 350-fold difference between the acceptable daily intake and the calculated reference dose for humans of 70 mg per day seems ... ...

    Abstract The data on the standards for chromium requirements and the safety of various chromium compounds and doses are reviewed. The 350-fold difference between the acceptable daily intake and the calculated reference dose for humans of 70 mg per day seems without precedent with respect to other nutritional minerals. Previous claims of mutagenic effects of chromium are of questionable relevance. While studies have found DNA fragmentation (clastogenic effects) by chromium picolinate, anecdotal reports of high-dose chromium picolinate toxicity are few and ambiguous. The beneficial effects of chromium on serum glucose and lipids and insulin resistance occur even in the healthy. Serum glucose can be improved by chromium supplementation in both types 1 and 2 diabetes, and the effect appears dose dependent. Relative absorption of various chromium compounds is summarized and the mechanism of low molecular weight chromium binding substance (LMWCr) in up-regulating the insulin effect eight-fold is discussed. There is evidence of hormonal effects of supplemental chromium besides the effect on insulin. Chromium supplementation does result in tissue retention, especially in the kidney, although no pathogenic effect has been demonstrated despite considerable study.
    MeSH term(s) Adult ; Blood Glucose/drug effects ; Chromium/administration & dosage ; Chromium/adverse effects ; Chromium/pharmacology ; Chromium Compounds/administration & dosage ; Chromium Compounds/adverse effects ; Chromium Compounds/pharmacology ; Diabetes Mellitus, Type 2/drug therapy ; Dietary Supplements ; Dose-Response Relationship, Drug ; Female ; Glucose/metabolism ; Humans ; Male ; Middle Aged ; Nutritional Requirements ; Randomized Controlled Trials as Topic
    Chemical Substances Blood Glucose ; Chromium Compounds ; Chromium (0R0008Q3JB) ; Glucose (IY9XDZ35W2)
    Language English
    Publishing date 2002-06
    Publishing country United States
    Document type Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The vitamin C:vitamin K3 system - enhancers and inhibitors of the anticancer effect.

    Lamson, Davis W / Gu, Yu-Huan / Plaza, Steven M / Brignall, Matthew S / Brinton, Cathy A / Sadlon, Angela E

    Alternative medicine review : a journal of clinical therapeutic

    2010  Volume 15, Issue 4, Page(s) 345–351

    Abstract: The oxidizing anticancer system of vitamin C and vitamin K₃ (VC:VK₃, producing hydrogen peroxide via superoxide) was combined individually with melatonin, curcumin, quercetin, or cholecalciferol (VD₃) to determine interactions. Substrates were LNCaP and ... ...

    Abstract The oxidizing anticancer system of vitamin C and vitamin K₃ (VC:VK₃, producing hydrogen peroxide via superoxide) was combined individually with melatonin, curcumin, quercetin, or cholecalciferol (VD₃) to determine interactions. Substrates were LNCaP and PC-3 prostate cancer cell lines. Three of the tested antioxidants displayed differences in cell line cytotoxicity. Melatonin combined with VC:VK₃ quenched the oxidizing effect, while VC:VK₃ applied 24 hours after melatonin showed no quenching. With increasing curcumin concentrations, an apparent combined effect of VC:VK₃ and curcumin occurred in LNCaP cells, but not PC-3 cells. Quercetin alone was cytotoxic on both cell lines, but demonstrated an additional 50-percent cytotoxicity on PC-3 cells when combined with VC:VK₃. VD₃ was effective against both cell lines, with more effect on PC-3. This effect was negated on LNCaP cells with the addition of VC:VK₃. In conclusion, a natural antioxidant can enhance or decrease the cytotoxicity of an oxidizing anticancer system in vitro, but generalizations about antioxidants cannot be made.
    MeSH term(s) Antineoplastic Agents/pharmacology ; Antioxidants/pharmacology ; Ascorbic Acid/pharmacology ; Cell Cycle/drug effects ; Cholecalciferol/pharmacology ; Curcumin/pharmacology ; Cytotoxins/pharmacology ; Drug Interactions ; Drug Therapy, Combination ; Humans ; Male ; Melatonin/pharmacology ; Oxidative Stress/drug effects ; Prostatic Neoplasms/drug therapy ; Quercetin/pharmacology ; Tumor Cells, Cultured ; Vitamin K 3/pharmacology
    Chemical Substances Antineoplastic Agents ; Antioxidants ; Cytotoxins ; Cholecalciferol (1C6V77QF41) ; Vitamin K 3 (723JX6CXY5) ; Quercetin (9IKM0I5T1E) ; Curcumin (IT942ZTH98) ; Melatonin (JL5DK93RCL) ; Ascorbic Acid (PQ6CK8PD0R)
    Language English
    Publishing date 2010-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1465535-4
    ISSN 1089-5159
    ISSN 1089-5159
    Database MEDical Literature Analysis and Retrieval System OnLINE

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