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Article: The serendipitous impact of COVID-19 pandemic: A rare opportunity for research and practice.

Sein, Maung Kyaw

International journal of information management

2020 Volume 55, Page(s) 102164

Abstract: In this opinion paper, I argue that the Covid-19 pandemic, as tragic and disastrous as it undoubtedly is, has also given us a rare opportunity to deeply examine the research and practice of information management in particular and information systems in ... ...

Abstract	In this opinion paper, I argue that the Covid-19 pandemic, as tragic and disastrous as it undoubtedly is, has also given us a rare opportunity to deeply examine the research and practice of information management in particular and information systems in general. To cope with the pandemic, we have retreated to the digital world and drastically changed the way we work. Yet these very practices can well shape the way we work in the post-pandemic world. Moreover, the pandemic is also a sharp lens through which we can study deep-rooted theoretical issues that otherwise would not have surfaced, or at least remained in the background. My call to the research community is to seize this rare opportunity.
Keywords	covid19
Language	English
Publishing date	2020-05-31
Publishing country	Netherlands
Document type	Journal Article
ISSN	0268-4012
ISSN	0268-4012
DOI	10.1016/j.ijinfomgt.2020.102164
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The serendipitous impact of COVID-19 pandemic

Sein, Maung Kyaw

International Journal of Information Management

A rare opportunity for research and practice

2020 Volume 55, Page(s) 102164

Keywords	Computer Networks and Communications ; Library and Information Sciences ; Information Systems ; covid19
Language	English
Publisher	Elsevier BV
Publishing country	us
Document type	Article ; Online
ISSN	0268-4012
DOI	10.1016/j.ijinfomgt.2020.102164
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The serendipitous impact of COVID-19 pandemic: A rare opportunity for research and practice

Sein, Maung Kyaw

Int J Inf Manage

Abstract	In this opinion paper, I argue that the Covid-19 pandemic, as tragic and disastrous as it undoubtedly is, has also given us a rare opportunity to deeply examine the research and practice of information management in particular and information systems in general. To cope with the pandemic, we have retreated to the digital world and drastically changed the way we work. Yet these very practices can well shape the way we work in the post-pandemic world. Moreover, the pandemic is also a sharp lens through which we can study deep-rooted theoretical issues that otherwise would not have surfaced, or at least remained in the background. My call to the research community is to seize this rare opportunity.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #436827
Database	COVID19

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Article ; Online: High vaccination coverage and inadequate knowledge: Findings from a community-based cross-sectional study on Japanese Encephalitis in Yangon, Myanmar.

Kyaw, Pyae Phyo / Shewade, Hemant Deepak / Kyaw, Nang Thu Thu / Hnin Phyo, Khaing / Lin, Htar Htar / Kyaw, Aye Mon Mon / Mya, Mg Mg / Thaung, Sein / Maung Maung, Yan Naung

F1000Research

2020 Volume 9, Page(s) 6

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Adolescent ; Adult ; Animals ; Child ; Child, Preschool ; Cross-Sectional Studies ; Encephalitis, Japanese/epidemiology ; Encephalitis, Japanese/prevention & control ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Infant ; Japanese Encephalitis Vaccines/administration & dosage ; Male ; Middle Aged ; Mosquito Vectors/virology ; Myanmar ; Vaccination Coverage/statistics & numerical data ; Young Adult
Chemical Substances	Japanese Encephalitis Vaccines
Language	English
Publishing date	2020-01-06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.21702.3
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Article ; Online: High vaccination coverage, inadequate knowledge and high vector density: Findings from a community-based cross-sectional study on Japanese Encephalitis in Yangon, Myanmar.

Kyaw, Pyae Phyo / Shewade, Hemant Deepak / Kyaw, Nang Thu Thu / Hnin Phyo, Khaing / Lin, Htar Htar / Kyaw, Aye Mon Mon / Mya, Mg Mg / Thaung, Sein / Maung Maung, Yan Naung

F1000Research

2020 Volume 9, Page(s) 6

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Adolescent ; Adult ; Child ; Child, Preschool ; Cross-Sectional Studies ; Encephalitis, Japanese/epidemiology ; Encephalitis, Japanese/prevention & control ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Infant ; Japanese Encephalitis Vaccines/administration & dosage ; Male ; Middle Aged ; Myanmar ; Parents ; Vaccination Coverage/statistics & numerical data ; Young Adult
Chemical Substances	Japanese Encephalitis Vaccines
Language	English
Publishing date	2020-06-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2699932-8
ISSN	2046-1402 ; 2046-1402
ISSN (online)	2046-1402
ISSN	2046-1402
DOI	10.12688/f1000research.21702.2
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Article ; Online: High vaccination coverage and inadequate knowledge

Pyae Phyo Kyaw / Hemant Deepak Shewade / Nang Thu Thu Kyaw / Khaing Hnin Phyo / Htar Htar Lin / Aye Mon Mon Kyaw / Mg Mg Mya / Sein Thaung / Yan Naung Maung Maung

F1000Research, Vol

Findings from a community-based cross-sectional study on Japanese Encephalitis in Yangon, Myanmar [version 3; peer review: 2 approved]

2020 Volume 9

Abstract: Background: Japanese encephalitis (JE) is a mosquito-borne disease with high case fatality and no specific treatment. Little is known about the community’s (especially parents/guardians of children) awareness regarding JE and its vaccine in Yangon region, ...

Abstract	Background: Japanese encephalitis (JE) is a mosquito-borne disease with high case fatality and no specific treatment. Little is known about the community’s (especially parents/guardians of children) awareness regarding JE and its vaccine in Yangon region, which bears the highest JE burden in Myanmar. Methods: We conducted a community-based cross-sectional study in Yangon region (2019) to explore the knowledge and perception of parents/guardians of 1-15 year-old children about JE disease, its vaccination and to describe JE vaccine coverage among 1-15 year-old children. We followed multi-stage random sampling (three stages) to select the 600 households with 1-15 year-old children from 30 clusters in nine townships. Analyses were weighted (inverse probability sampling) for the multi-stage sampling design. Results: Of 600 parents/guardians, 38% exhibited good knowledge of JE, 55% perceived JE as serious in children younger than 15 years and 59% perceived the vaccine to be effective. Among all the children in the 600 households, the vaccination coverage was 97% (831/855). Conclusion: In order to reduce JE incidence in the community, focus on an intensified education program is necessary to sustain the high vaccine coverage in the community.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2020-09-01T00:00:00Z
Publisher	F1000 Research Ltd
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: High sustained virologic response in genotypes 3 and 6 with generic NS5A inhibitor and sofosbuvir regimens in chronic HCV in myanmar.

Hlaing, Naomi Khaing Than / Nangia, Gayatri / Tun, Kyaw Thet / Lin, Sithu / Maung, Moe Zaw / Myint, Khin Thuzar / Kyaw, A Mi Mi / Maung, Soe Thiha / Sein Win, Sithu / Bwa, Aung Hlaing / Loza, Bao-Li / Win, Khin Maung / Reddy, K Rajender

Journal of viral hepatitis

2019 Volume 26, Issue 10, Page(s) 1186–1199

Abstract: Exclusive HCV therapy clinical trials with genotype 6 patients in high prevalence areas have been sparse. We analysed the safety and efficacy of two generic, pangenotypic NS5A/NS5B combination oral DAA regimens, primarily in genotypes 3 and 6, in a real- ... ...

Abstract	Exclusive HCV therapy clinical trials with genotype 6 patients in high prevalence areas have been sparse. We analysed the safety and efficacy of two generic, pangenotypic NS5A/NS5B combination oral DAA regimens, primarily in genotypes 3 and 6, in a real-world setting: (a) daclatasvir/sofosbuvir (DCV/SOF) ± ribavirin (RBV) and (b) Velpatasvir/sofosbuvir (VEL/SOF ± RBV). Between December 2015 and November 2017, data from 522 patients were analysed, 311 of whom were treated with DCV/SOF ± RBV for 12/24 weeks (genotype 3: n = 193, genotype 6: n = 89) and 211 were treated with VEL/SOF ± RBV for 12/24 weeks (genotype 3: n = 83, genotype 6: n = 77). Overall SVR rates were high for both DCV/SOF ± RBV (96.1%, n = 299/311) and VEL/SOF ± RBV (95.3%, n = 201/211), and there was a good adverse event profile. Treatment naïve status and inclusion of RBV (in advanced fibrosis/cirrhosis) were significant independent predictors of achieving SVR12, while type of DAA regimen was not predictive. In this large cohort of genotypes 3 (n = 276) and 6 (n = 166; n = 127 unique subtype of 6c-l), high SVR rates of 94.9% (n = 262/276) and 95.2% (n = 158/166), respectively, were noted. In conclusion, generic and pangenotypic DCV/SOF and VEL/SOF ± RBV regimens were highly effective and safe, in genotypes 3 and 6 chronic HCV in Myanmar. These efficacious pangenotypic regimens suggest that baseline genotype testing can be eliminated moving forward. While RBV may still be needed for those with advanced fibrosis/cirrhosis, in a global elimination strategy it would not be practical even if it does compromise SVR in a minority with difficult to treat characteristics.
MeSH term(s)	Adult ; Aged ; Antiviral Agents/therapeutic use ; Carbamates/therapeutic use ; Drug Therapy, Combination/methods ; Female ; Genotype ; Hepacivirus/classification ; Hepacivirus/genetics ; Hepacivirus/isolation & purification ; Hepatitis C, Chronic/drug therapy ; Hepatitis C, Chronic/virology ; Heterocyclic Compounds, 4 or More Rings/therapeutic use ; Humans ; Imidazoles/therapeutic use ; Male ; Middle Aged ; Myanmar ; Ribavirin/therapeutic use ; Sofosbuvir/therapeutic use ; Sustained Virologic Response
Chemical Substances	Antiviral Agents ; Carbamates ; Heterocyclic Compounds, 4 or More Rings ; Imidazoles ; Ribavirin (49717AWG6K) ; velpatasvir (KCU0C7RS7Z) ; daclatasvir (LI2427F9CI) ; Sofosbuvir (WJ6CA3ZU8B)
Language	English
Publishing date	2019-06-10
Publishing country	England
Document type	Journal Article ; Observational Study
ZDB-ID	1212497-7
ISSN	1365-2893 ; 1352-0504
ISSN (online)	1365-2893
ISSN	1352-0504
DOI	10.1111/jvh.13133
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Article ; Online: Effectiveness of a novel long-lasting pyriproxyfen larvicide (SumiLarv®2MR) against Aedes mosquitoes in schools in Yangon, Myanmar.

Oo, Sai Zaw Min / Thaung, Sein / Maung, Yan Naung Maung / Aye, Khin Myo / Aung, Zar Zar / Thu, Hlaing Myat / Thant, Kyaw Zin / Minakawa, Noboru

Parasites & vectors

2018 Volume 11, Issue 1, Page(s) 16

Abstract: Background: Mosquito-borne diseases are prevalent in Myanmar, with the number of dengue cases showing a significant increase in recent years. Dengue vectors have developed resistance to insecticides and currently used larvicides show only short-term ... ...

Abstract	Background: Mosquito-borne diseases are prevalent in Myanmar, with the number of dengue cases showing a significant increase in recent years. Dengue vectors have developed resistance to insecticides and currently used larvicides show only short-term effectiveness. As a result, an alternative larvicide is urgently needed. The present study evaluated the larvicidal effectiveness of long-lasting pyriproxyfen resin discs (SumiLarv®2MR) against dengue virus vectors in schools in Hlaing Thar Yar Township, Yangon. Results: The proportion of Aedes mosquito-infested containers was significantly reduced in the schools applied with the larvicide (OR: 0.24, 95% CI: 0.12-0.48) while there was little reduction noted in the control schools (OR: 0.97, 95% CI: 0.55-1.72). The density of infested containers was also significantly reduced in the intervention schools (Beta: -1.50, 95% CI: -1.98- -1.04), but there was no significant reduction in density in the control schools (Beta: -0.19, 95% CI: -0.53-0.14). The proportion of adult emergence was less than 20% in the treated water collected from the intervention schools for six months, while the proportion was over 90% in the untreated water. In addition, eight-month-old SumiLarv®2MR resin discs were still 100% effective when tested in the laboratory. More than 50% of the discs disappeared from treated containers within two months of intervention. Conclusions: SumiLarv®2MR was effective in reducing Aedes-infested containers at least six months after its application in schools. This new pyriproxyfen formulation has great potential for improving the current dengue vector control program in Myanmar.
MeSH term(s)	Aedes/drug effects ; Animals ; Biological Assay ; Insecticides/pharmacology ; Mosquito Vectors/drug effects ; Myanmar ; Pyridines/pharmacology ; Schools
Chemical Substances	Insecticides ; Pyridines ; pyriproxyfen (3Q9VOR705O)
Language	English
Publishing date	2018--06
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2409480-8
ISSN	1756-3305 ; 1756-3305
ISSN (online)	1756-3305
ISSN	1756-3305
DOI	10.1186/s13071-017-2603-9
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Article ; Online: Clinical importance of the Mandalay spitting cobra (Naja mandalayensis) in Upper Myanmar - Bites, envenoming and ophthalmia.

Sai-Sein-Lin-Oo / Myat-Thet-Nwe / Khin-Maung-Gyi / Than-Aye / Mi-Mi-Khine / Myat-Myat-Thein / Myo-Thant / Pyae-Phyo-Aung / Oakkar-Kyaw-Khant / Aye-Zarchi-San / Du-Wun-Moe / Htay-Aung / O'Shea, Mark / Mahmood, Mohammad Afzal / Peh, Chen Au / White, Julian / Warrell, David A

Toxicon : official journal of the International Society on Toxinology

2020 Volume 184, Page(s) 39–47

Abstract: Examination of 18 cobras brought to three hospitals in the Mandalay Region by patients bitten or spat at by them distinguished 3 monocled cobras (Naja kaouthia) and 15 Mandalay spitting cobras (N. mandalayensis), based on their morphological ... ...

Abstract	Examination of 18 cobras brought to three hospitals in the Mandalay Region by patients bitten or spat at by them distinguished 3 monocled cobras (Naja kaouthia) and 15 Mandalay spitting cobras (N. mandalayensis), based on their morphological characteristics. We confirm and extend the known distributions and habitats of both N. mandalayensis and N. kaouthia in Upper Myanmar. Clinical symptoms of local and systemic envenoming by N. mandalayensis are described for the first time. These included local swelling, blistering and necrosis and life-threatening systemic neurotoxicity. More information is needed about the clinical phenotype and management of bites by N. mandalayensis, the commoner of the two cobras in Upper Myanmar. Since the current cobra antivenom manufactured in Myanmar has lower pre-clinical efficacy against N. mandalayensis than N. kaouthia, there is a need for more specific antivenom therapy.
MeSH term(s)	Animals ; Antivenins ; Elapid Venoms ; Elapidae ; Endophthalmitis ; Myanmar ; Naja ; Snake Bites
Chemical Substances	Antivenins ; Elapid Venoms
Language	English
Publishing date	2020-06-03
Publishing country	England
Document type	Journal Article
ZDB-ID	204479-1
ISSN	1879-3150 ; 0041-0101
ISSN (online)	1879-3150
ISSN	0041-0101
DOI	10.1016/j.toxicon.2020.05.023
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Article: Effectiveness of a novel long-lasting pyriproxyfen larvicide (SumiLarv®2MR) against Aedes mosquitoes in schools in Yangon, Myanmar

Oo, Sai Zaw Min / Aung, Zar Zar / Aye, Khin Myo / Maung, Yan Naung Maung / Minakawa, Noboru / Thant, Kyaw Zin / Thaung, Sein / Thu, Hlaing Myat

Parasites & vectors. 2018 Dec., v. 11, no. 1

2018

Abstract: BACKGROUND: Mosquito-borne diseases are prevalent in Myanmar, with the number of dengue cases showing a significant increase in recent years. Dengue vectors have developed resistance to insecticides and currently used larvicides show only short-term ... ...

Abstract	BACKGROUND: Mosquito-borne diseases are prevalent in Myanmar, with the number of dengue cases showing a significant increase in recent years. Dengue vectors have developed resistance to insecticides and currently used larvicides show only short-term effectiveness. As a result, an alternative larvicide is urgently needed. The present study evaluated the larvicidal effectiveness of long-lasting pyriproxyfen resin discs (SumiLarv®2MR) against dengue virus vectors in schools in Hlaing Thar Yar Township, Yangon. RESULTS: The proportion of Aedes mosquito-infested containers was significantly reduced in the schools applied with the larvicide (OR: 0.24, 95% CI: 0.12–0.48) while there was little reduction noted in the control schools (OR: 0.97, 95% CI: 0.55–1.72). The density of infested containers was also significantly reduced in the intervention schools (Beta: -1.50, 95% CI: -1.98– -1.04), but there was no significant reduction in density in the control schools (Beta: -0.19, 95% CI: -0.53–0.14). The proportion of adult emergence was less than 20% in the treated water collected from the intervention schools for six months, while the proportion was over 90% in the untreated water. In addition, eight-month-old SumiLarv®2MR resin discs were still 100% effective when tested in the laboratory. More than 50% of the discs disappeared from treated containers within two months of intervention. CONCLUSIONS: SumiLarv®2MR was effective in reducing Aedes-infested containers at least six months after its application in schools. This new pyriproxyfen formulation has great potential for improving the current dengue vector control program in Myanmar.
Keywords	adults ; Aedes ; containers ; dengue ; Dengue virus ; insect infestations ; insecticide resistance ; larvicides ; mosquito-borne diseases ; pyriproxyfen ; schools ; vector control ; Myanmar
Language	English
Dates of publication	2018-12
Size	p. 16.
Publishing place	BioMed Central
Document type	Article
ZDB-ID	2409480-8
ISSN	1756-3305
ISSN	1756-3305
DOI	10.1186/s13071-017-2603-9
Database	NAL-Catalogue (AGRICOLA)

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