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  1. Article ; Online: Vacuolated lymphocytes, a leading piece of diagnostic evidence for a rare storage disorder.

    Jamali, Elham / Ranjbaran, Reza

    Blood

    2023  Volume 141, Issue 21, Page(s) 2662

    MeSH term(s) Humans ; Lymphocytes ; Metabolic Diseases ; Leukocyte Disorders
    Language English
    Publishing date 2023-05-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80069-7
    ISSN 1528-0020 ; 0006-4971
    ISSN (online) 1528-0020
    ISSN 0006-4971
    DOI 10.1182/blood.2023019735
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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.140: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 364: Show issues

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  2. Article: Suprachoroidal hemorrhage during phacoemulsification surgery associated with recent COVID-19: A report of two cases.

    Jamali, Hossein / Sadeghi, Elham / Nowroozzadeh, Mohammad Hossein

    Clinical case reports

    2022  Volume 10, Issue 8, Page(s) e6204

    Abstract: To report two cases of suprachoroidal hemorrhage during otherwise uncomplicated phacoemulsification, in whom COVID-19 was documented with a positive PCR test about 1 month before the surgery and the importance of postponing elective surgeries for several ...

    Abstract To report two cases of suprachoroidal hemorrhage during otherwise uncomplicated phacoemulsification, in whom COVID-19 was documented with a positive PCR test about 1 month before the surgery and the importance of postponing elective surgeries for several months after infection.
    Language English
    Publishing date 2022-08-09
    Publishing country England
    Document type Editorial
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.6204
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  3. Article ; Online: Early induction of cytokine release syndrome by rapidly generated CAR T cells in preclinical models.

    Jamali, Arezoo / Ho, Naphang / Braun, Angela / Adabi, Elham / Thalheimer, Frederic B / Buchholz, Christian J

    EMBO molecular medicine

    2024  Volume 16, Issue 4, Page(s) 784–804

    Abstract: Cytokine release syndrome (CRS) is a significant side-effect of conventional chimeric antigen receptor (CAR) T-cell therapy. To facilitate patient accessibility, short-term (st) CAR T cells, which are administered to patients only 24 h after vector ... ...

    Abstract Cytokine release syndrome (CRS) is a significant side-effect of conventional chimeric antigen receptor (CAR) T-cell therapy. To facilitate patient accessibility, short-term (st) CAR T cells, which are administered to patients only 24 h after vector exposure, are in focus of current investigations. Their impact on the incidence and severity of CRS has been poorly explored. Here, we evaluated CD19-specific stCAR T cells in preclinical models. In co-culture with tumor cells and monocytes, stCAR T cells exhibited anti-tumoral activity and potent release of CRS-related cytokines (IL-6, IFN-γ, TNF-α, GM-CSF, IL-2, IL-10). When administered to NSG-SGM3 mice, stCAR T cells, but not conventional CAR T cells, induced severe acute adverse events within 24 h, including hypothermia and weight loss, as well as high body scores, independent of the presence of tumor target cells. Human (IFN-γ, TNF-α, IL-2, IL-10) and murine (MCP-1, IL-6, G-CSF) cytokines, typical for severe CRS, were systemically elevated. Our data highlight potential safety risks of rapidly manufactured CAR T cells and suggest NSG-SGM3 mice as sensitive model for their preclinical safety evaluation.
    MeSH term(s) Humans ; Animals ; Mice ; Cytokine Release Syndrome ; Interleukin-10 ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Interleukin-2 ; Cytokines ; Immunotherapy, Adoptive ; T-Lymphocytes ; Neoplasms
    Chemical Substances Interleukin-10 (130068-27-8) ; Interleukin-6 ; Tumor Necrosis Factor-alpha ; Interleukin-2 ; Cytokines
    Language English
    Publishing date 2024-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2467145-9
    ISSN 1757-4684 ; 1757-4676
    ISSN (online) 1757-4684
    ISSN 1757-4676
    DOI 10.1038/s44321-024-00055-9
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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Suprachoroidal hemorrhage during phacoemulsification surgery associated with recent COVID‐19

    Hossein Jamali / Elham Sadeghi / Mohammad Hossein Nowroozzadeh

    Clinical Case Reports, Vol 10, Iss 8, Pp n/a-n/a (2022)

    A report of two cases

    2022  

    Abstract: Abstract To report two cases of suprachoroidal hemorrhage during otherwise uncomplicated phacoemulsification, in whom COVID‐19 was documented with a positive PCR test about 1 month before the surgery and the importance of postponing elective surgeries ... ...

    Abstract Abstract To report two cases of suprachoroidal hemorrhage during otherwise uncomplicated phacoemulsification, in whom COVID‐19 was documented with a positive PCR test about 1 month before the surgery and the importance of postponing elective surgeries for several months after infection.
    Keywords case report ; cataract surgery ; COVID‐19 ; phacoemulsification ; suprachoroidal hemorrhage ; Medicine ; R ; Medicine (General) ; R5-920
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Concise review: The heterogenous roles of BATF3 in cancer oncogenesis and dendritic cells and T cells differentiation and function considering the importance of BATF3-dependent dendritic cells.

    Dabbaghipour, Reza / Ahmadi, Elham / Entezam, Mona / Farzam, Omid Rahbar / Sohrabi, Sepideh / Jamali, Sajjad / Sichani, Ali Saber / Paydar, Hadi / Baradaran, Behzad

    Immunogenetics

    2024  Volume 76, Issue 2, Page(s) 75–91

    Abstract: The transcription factor, known as basic leucine zipper ATF-like 3 (BATF3), is a crucial contributor to the development of conventional type 1 dendritic cells (cDC1), which is definitely required for priming CD8 + T cell-mediated immunity against ... ...

    Abstract The transcription factor, known as basic leucine zipper ATF-like 3 (BATF3), is a crucial contributor to the development of conventional type 1 dendritic cells (cDC1), which is definitely required for priming CD8 + T cell-mediated immunity against intracellular pathogens and malignancies. In this respect, BATF3-dependent cDC1 can bring about immunological tolerance, an autoimmune response, graft immunity, and defense against infectious agents such as viruses, microbes, parasites, and fungi. Moreover, the important function of cDC1 in stimulating CD8 + T cells creates an excellent opportunity to develop a highly effective target for vaccination against intracellular pathogens and diseases. BATF3 has been clarified to control the development of CD8α
    MeSH term(s) Humans ; Animals ; Mice ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Basic-Leucine Zipper Transcription Factors/genetics ; Basic-Leucine Zipper Transcription Factors/metabolism ; CD8-Positive T-Lymphocytes ; Neoplasms/therapy ; Neoplasms/metabolism ; Dendritic Cells ; Carcinogenesis ; Mice, Inbred C57BL ; Mice, Knockout ; Tumor Microenvironment
    Chemical Substances Repressor Proteins ; Basic-Leucine Zipper Transcription Factors
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 186560-2
    ISSN 1432-1211 ; 0093-7711
    ISSN (online) 1432-1211
    ISSN 0093-7711
    DOI 10.1007/s00251-024-01335-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1052: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Risk factors associated with vitamin D deficiency in preterm neonates: a single-center step-wise regression analysis.

    Jamali, Zahra / Ghorbani, Fereshteh / Shafie'ei, Mohammad / Tolooefar, Fatemeh / Maleki, Elham

    BMC pediatrics

    2023  Volume 23, Issue 1, Page(s) 324

    Abstract: Background: Vitamin D deficiency is particularly concerning in pregnant women, leading to various health-related issues in mothers and their babies, especially those born prematurely, including neonatal skeletal and respiratory disorders. In addition, ... ...

    Abstract Background: Vitamin D deficiency is particularly concerning in pregnant women, leading to various health-related issues in mothers and their babies, especially those born prematurely, including neonatal skeletal and respiratory disorders. In addition, there have been several reports indicating the presence of multiple impactful factors in the development of vitamin D deficiency. Therefore, we aimed to evaluate the vitamin D level in very preterm and moderately preterm newborns and investigate its association with presumed influential factors.
    Methods: This cross-sectional descriptive study was performed on 54 mothers and their preterm neonates with gestational ages less than 34 weeks at delivery (i.e., very preterm and moderately preterm). After the serum vitamin D levels were determined from samples obtained in the first 24 h after birth, the babies were divided into two groups based on the presence or absence of deficiency. The relationship between several factors and the neonatal serum vitamin D level was investigated separately and in a linear step-wise regression model.
    Results: The differences between the groups regarding maternal age, gestational age, neonate's gender, birth weight, and delivery method with neonatal vitamin D levels were not statistically significant. However, maternal vitamin D levels strongly correlated with neonatal vitamin D levels (P-value < 0.001, r = 0.636). The regression model also yielded a strong predictive capability (P-value < 0.001, Adjusted R
    Conclusions: Low vitamin D levels in pregnant mothers correlate with deficient levels in their preterm neonates. Therefore, as vitamin D deficiency significantly affects both the mother's and newborn's health, it is recommended that healthcare providers provide comprehensive plans for vitamin D supplementation during pregnancy.
    MeSH term(s) Infant, Newborn ; Humans ; Female ; Pregnancy ; Cross-Sectional Studies ; Vitamin D Deficiency/complications ; Vitamin D Deficiency/diagnosis ; Vitamin D ; Risk Factors ; Vitamins ; Regression Analysis
    Chemical Substances Vitamin D (1406-16-2) ; Vitamins
    Language English
    Publishing date 2023-06-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-023-04088-w
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  7. Article ; Online: Seroepidemiological study on Coxiella burnetii and associated risk factors in ruminants at Kurdistan Province, west of Iran.

    Fakour, Shahin / Jamali, Rojin / Ahmadi, Elham

    Comparative immunology, microbiology and infectious diseases

    2021  Volume 78, Page(s) 101691

    Abstract: Q fever is zoonotic disease caused by Coxiella burnetii. Ruminants are the main reservoir of this pathogen, which is often asymptomatic but lead to abortion. This study aims to survey the seroprevalence and risk factors of this zoonose among ruminants in ...

    Abstract Q fever is zoonotic disease caused by Coxiella burnetii. Ruminants are the main reservoir of this pathogen, which is often asymptomatic but lead to abortion. This study aims to survey the seroprevalence and risk factors of this zoonose among ruminants in Kurdistan province, the west of Iran. 480 blood samples were collected from ruminants including sheep, goats and cows, each 160 samples, in the age groups of <1, ≥1-3, >3-5 year with and without the history of abortion in two groups border and non-border cities in Kurdistan province. Serums were tested by use of indirect ELISA to determine specific antibodies against C. burnetii. The results indicate the seroprevalence of 46.6 % for Q fever. Seroprevalence in sheep, goats and cows were 28.58 % (n = 64), 45.53 % (n = 102) and 25.89 % (n = 58), respectively. Seroprevalence is significantly higher in animals with abortion than in those without such history (P < 0.05). The seroprevalence in the border cities has been significantly higher than other geographical areas (P < 0.05). Seroprevalence had no significant correlation with animal age (P> 0.05). This study is the first seroepidemiological study done on Q fever in ruminants of Kurdistan province, Iran. The results indicate the high seroprevalence of Coxiella burnetii in the area under the study. Therefore, doing an epidemiologically study aimed at isolating C. brunetii in the human population of Kurdistan province is recommended, so that the epidemiological aspect of this pathogen in the people of Kurdistan province be clarified and subsequently disease control and prevention programs be applied.
    MeSH term(s) Animals ; Antibodies, Bacterial ; Cattle ; Cattle Diseases/epidemiology ; Coxiella burnetii ; Female ; Goat Diseases/epidemiology ; Iran/epidemiology ; Pregnancy ; Risk Factors ; Ruminants ; Seroepidemiologic Studies ; Sheep ; Sheep Diseases/epidemiology
    Chemical Substances Antibodies, Bacterial
    Language English
    Publishing date 2021-07-07
    Publishing country England
    Document type Journal Article
    ZDB-ID 436522-7
    ISSN 1878-1667 ; 0147-9571
    ISSN (online) 1878-1667
    ISSN 0147-9571
    DOI 10.1016/j.cimid.2021.101691
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1443: Show issues Location:
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  8. Article ; Online: Personal Experience With COVID-19 and Community Screening of Diabetic Retinopathy in Iran.

    Jamali, Sepideh / Ashrafi, Elham / Mohammadi, Seyed Farzad

    Journal of diabetes science and technology

    2020  Volume 14, Issue 4, Page(s) 737–738

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/prevention & control ; Diabetes Mellitus/therapy ; Diabetic Retinopathy/diagnosis ; Humans ; Iran ; Mass Screening/methods ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Risk Factors ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-27
    Publishing country United States
    Document type Journal Article
    ISSN 1932-2968
    ISSN (online) 1932-2968
    DOI 10.1177/1932296820930045
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  9. Article ; Online: Comparison of Portable Cameras for Diabetic Retinopathy Community Screening.

    Jamali, Sepideh / Abrishami, Mojtaba / Lashay, Alireza / Ashrafi, Elham / Adibi, Hossein / Ghaderi, Ebrahim / Hatef, Elham / Mohammadi, Seyed Farzad

    Journal of diabetes science and technology

    2020  Volume 15, Issue 1, Page(s) 201–202

    MeSH term(s) Diabetes Mellitus ; Diabetic Retinopathy/diagnosis ; Humans ; Mass Screening ; Photography
    Language English
    Publishing date 2020-05-29
    Publishing country United States
    Document type Letter
    ISSN 1932-2968
    ISSN (online) 1932-2968
    DOI 10.1177/1932296820929357
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  10. Article ; Online: Natural antimicrobial-loaded nanoemulsions for the control of food spoilage/pathogenic microorganisms.

    Jamali, Seyedeh Narges / Assadpour, Elham / Feng, Jianguo / Jafari, Seid Mahdi

    Advances in colloid and interface science

    2021  Volume 295, Page(s) 102504

    Abstract: Both consumers and producers of food products are looking for natural ingredients and efficient formulation strategies to improve the shelf life of final products. Natural antimicrobial ingredients such as essential oils can be applied as alternatives to ...

    Abstract Both consumers and producers of food products are looking for natural ingredients and efficient formulation strategies to improve the shelf life of final products. Natural antimicrobial ingredients such as essential oils can be applied as alternatives to synthetic preservatives, but their main challenge is low stability, adverse effects on sensory properties, low solubility, high needed doses, etc. Formulation of these bioactive compounds into nanoemulsions can be an efficient strategy to improve their properties and practical applications in food products. In this review, after an overview on nanoemulsion formulation, ingredients and fabrication methods, different types of natural antimicrobial agents have been discussed briefly. In addition, properties and action mechanisms of antimicrobial-loaded nanoemulsions, along with their application in preservation and shelf life improvement of different food products have been explained. Finally, safety and regulatory issues of antimicrobial delivery via nanoemulsions have been examined. As a conclusion antimicrobial-loaded nanoemulsions can be promising candidates and alternatives for common synthetic preservatives in real food systems.
    MeSH term(s) Anti-Bacterial Agents ; Anti-Infective Agents/pharmacology ; Food ; Food Microbiology ; Oils, Volatile/pharmacology
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents ; Oils, Volatile
    Language English
    Publishing date 2021-08-06
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 210507-x
    ISSN 1873-3727 ; 0001-8686
    ISSN (online) 1873-3727
    ISSN 0001-8686
    DOI 10.1016/j.cis.2021.102504
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