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  1. Article ; Online: Evaluation of the Nelson Criteria as an Indicator for Nonsurgical Admission in Trauma Patients.

    Lee, Janet S / Khan, Abid D / Schlitzkus, Lisa / Schmoekel, Nathan / Stassinopoulos, Jerry / Brockman, Valerie / Schroeppel, Thomas J

    The American surgeon

    2022  Volume 88, Issue 7, Page(s) 1537–1540

    Abstract: ... admission to nonsurgical services. The Nelson score provides an objective scoring system that helps identify ... of the Nelson criteria in determining the most appropriate admission service. A retrospective review was ... Patients with Nelson score ≥6 were older with more comorbidities, had a lower injury severity score (7.5 vs ...

    Abstract Geriatric patients with complex medical comorbidities who sustain minor injuries may warrant admission to nonsurgical services. The Nelson score provides an objective scoring system that helps identify patients appropriate for nonsurgical admission (NSA). The purpose of this study is to assess the utility of the Nelson criteria in determining the most appropriate admission service. A retrospective review was performed on patients ≥65 years admitted from 12/2016 to 11/2020. 2410 patients met the inclusion criteria. Patients with Nelson score ≥6 were older with more comorbidities, had a lower injury severity score (7.5 vs 12.5, p<0.0001), and a higher rate of NSA (29.2% vs 12.7%, p<0.0001) compared to patients with Nelson score <6. On the multivariable logistic regression, admission service was not identified as an independent predictor of mortality. Utilizing the Nelson criteria may provide an objective measure to stratify and identify patients who would benefit from NSA.
    MeSH term(s) Aged ; Comorbidity ; Hospitalization ; Humans ; Injury Severity Score ; Logistic Models ; Retrospective Studies ; Trauma Centers ; Wounds and Injuries/therapy
    Language English
    Publishing date 2022-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 202465-2
    ISSN 1555-9823 ; 0003-1348
    ISSN (online) 1555-9823
    ISSN 0003-1348
    DOI 10.1177/00031348221082272
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  2. Article ; Online: Relationship of the Nelson Denny Reading Test to scores on the National Physical Therapy Licensure Examination.

    Aldridge, Roy Lee / Keith, Becky / Sloas, Stacy / Mott-Murphree, Ashley

    Journal of allied health

    2010  Volume 39, Issue 2, Page(s) 72–75

    Abstract: ... by the Nelson Denny Reading Test and scaled scores on the National Physical Therapy Licensure Examination (NPTE ... Sixty-seven graduate students from Arkansas State University participated in this study. The Nelson ...

    Abstract This study examined the relationship between scaled scores of reading comprehension as measured by the Nelson Denny Reading Test and scaled scores on the National Physical Therapy Licensure Examination (NPTE). Sixty-seven graduate students from Arkansas State University participated in this study. The Nelson Denny Reading Test was given at the initiation of the physical therapy program, and the NPTE was taken after successful completion of the graduate program in physical therapy. A correlation analysis examined the scaled scores of these graduates from the Reading Test and the NPTE. Analysis revealed that a moderate positive relationship and statistically significant difference existed between scaled scores on the Reading Test and the NPTE for those graduates who passed the NPTE their first time.
    MeSH term(s) Education, Graduate ; Educational Measurement ; Educational Status ; Female ; Humans ; Licensure ; Male ; Physical Therapy Specialty/education
    Language English
    Publishing date 2010
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197884-6
    ISSN 1945-404X ; 0090-7421
    ISSN (online) 1945-404X
    ISSN 0090-7421
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  3. Article: [Rezension von: Nelson, Robert H., Public lands and private rights]

    Anderson, Terry Lee / Nelson, Robert H

    Journal of economic literature 34 ,4, S. 2000-2001

    1996  

    Author's details Terry L. Anderson
    Keywords 40;49
    Language English
    Publisher Assoc
    Publishing place Nashville, Tenn
    Document type Article
    ZDB-ID 3076-4 ; 2010159-4
    ISSN 0022-0515
    ISSN 0022-0515
    Database ECONomics Information System

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  4. Book ; Online: Cancer biomarkers and targets in digestive organs

    Yee, Nelson S. / Lee, Nikki P.

    (Biomedicines. Special issue)

    2019  

    Author's details special issue editors Nelson S. Yee, Nikki P. Lee
    Series title Biomedicines. Special issue
    Language English
    Size 1 Online-Ressource (vii, 136 Seiten), Illustrationen, Diagramme
    Publisher MDPI
    Publishing place Basel ; Beijing ; Wuhan ; Barcelona ; Belgrade
    Publishing country Switzerland
    Document type Book ; Online
    Note Reprint of articles from the special issue published online in the open access journal "Biomedicines" (ISSN 2227-9059) from 2017 to 2019 (available at: https://www.mdpi.com/journal/biomedicines/special_issues/organs ) ; Open Access
    HBZ-ID HT020259389
    ISBN 978-3-03921-464-8 ; 9783039214631 ; 3-03921-464-0 ; 3039214632
    DOI 10.3390/books978-3-03921-464-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  5. Article ; Online: Commentary on: "Inherited DNA-repair gene mutations in men with metastatic prostate cancer." Pritchard CC, Mateo J, Walsh MF, De Sarkar N, Abida W, Beltran H, Garofalo A, Gulati R, Carreira S, Eeles R, Elemento O, Rubin MA, Robinson D, Lonigro R, Hussain M, Chinnaiyan A, Vinson J, Filipenko J, Garraway L, Taplin ME, AlDubayan S, Han GC, Beightol M, Morrissey C, Nghiem B, Cheng HH, Montgomery B, Walsh T, Casadei S, Berger M, Zhang L, Zehir A, Vijai J, Scher HI, Sawyers C, Schultz N, Kantoff PW, Solit D, Robson M, Van Allen EM, Offit K, de Bono J, Nelson PS. N Engl J Med. 2016 Aug 4;375(5):443-53.

    Lee, Byron H

    Urologic oncology

    2017  Volume 35, Issue 9, Page(s) 575–576

    Abstract: Background: Inherited mutations in DNA-repair genes such as BRCA2 are associated with increased risks of lethal prostate cancer. Although the prevalence of germline mutations in DNA-repair genes among men with localized prostate cancer who are ... ...

    Abstract Background: Inherited mutations in DNA-repair genes such as BRCA2 are associated with increased risks of lethal prostate cancer. Although the prevalence of germline mutations in DNA-repair genes among men with localized prostate cancer who are unselected for family predisposition is insufficient to warrant routine testing, the frequency of such mutations in patients with metastatic prostate cancer has not been established.
    Methods: We recruited 692 men with documented metastatic prostate cancer who were unselected for family history of cancer or age at diagnosis. We isolated germline DNA and used multiplex sequencing assays to assess mutations in 20 DNA-repair genes associated with autosomal dominant cancer-predisposition syndromes.
    Results: A total of 84 germline DNA-repair gene mutations that were presumed to be deleterious were identified in 82 men (11.8%); mutations were found in 16 genes, including BRCA2 (37 men [5.3%]), ATM (11 [1.6%]), CHEK2 (10 [1.9% of 534 men with data]), BRCA1 (6 [0.9%]), RAD51D (3 [0.4%]), and PALB2 (3 [0.4%]). Mutation frequencies did not differ according to whether a family history of prostate cancer was present or according to age at diagnosis. Overall, the frequency of germline mutations in DNA-repair genes among men with metastatic prostate cancer significantly exceeded the prevalence of 4.6% among 499 men with localized prostate cancer (P<0.001), including men with high-risk disease, and the prevalence of 2.7% in the Exome Aggregation Consortium, which includes 53,105 persons without a known cancer diagnosis (P<0.001).
    Conclusions: In our multicenter study, the incidence of germline mutations in genes mediating DNA-repair processes among men with metastatic prostate cancer was 11.8%, which was significantly higher than the incidence among men with localized prostate cancer. The frequencies of germline mutations in DNA-repair genes among men with metastatic disease did not differ significantly according to age at diagnosis or family history of prostate cancer. (Funded by Stand Up To Cancer and others.).
    MeSH term(s) BRCA1 Protein/genetics ; BRCA2 Protein/genetics ; DNA Repair/genetics ; Genetic Predisposition to Disease ; Germ-Line Mutation ; Humans ; Male ; Neoplasm Metastasis ; Prostatic Neoplasms/genetics ; Prostatic Neoplasms/pathology
    Chemical Substances BRCA1 Protein ; BRCA1 protein, human ; BRCA2 Protein ; BRCA2 protein, human
    Language English
    Publishing date 2017
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1336505-8
    ISSN 1873-2496 ; 1078-1439
    ISSN (online) 1873-2496
    ISSN 1078-1439
    DOI 10.1016/j.urolonc.2017.07.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4817: Show issues Location:
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  6. Book ; Online: Cancer Biomarkers and Targets in Digestive Organs

    Yee, Nelson / Lee, Nikki

    2019  

    Abstract: Identification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also led ...

    Abstract Identification and development of cancer biomarkers and targets have greatly accelerated progress towards precision medicine in oncology. Studies of tumor biology have not only provided insights into the mechanisms underlying carcinogenesis, but also led to discovery of molecules that have been developed into cancer biomarkers and targets. Multi-platforms for molecular characterization of tumors using next-generation genomic sequencing, immunohistochemistry, in situ hybridization, and blood-based biopsies have greatly expanded the portfolio of potential biomarkers and targets. These cancer biomarkers have been developed for diagnosis, early detection, prognosis, and prediction of treatment response. The molecular targets have been exploited for anti-cancer therapy and delivery of therapeutic agents. This Special Issue of Biomedicines focuses on recent advances in the discovery, characterization, translation, and clinical application of cancer biomarkers and targets in malignant diseases of the digestive system. The goal is to stimulate basic and translational research and clinical collaboration in this exciting field with the hope of developing strategies for prevention and early detection/diagnosis of cancer in digestive organs, and improving therapeutic and psychosocial outcomes in patients with these malignant diseases
    Keywords Medicine (General)
    Size 1 electronic resource (146 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note eng ; Open Access
    HBZ-ID HT020323961
    ISBN 9783039214631 ; 9783039214648 ; 3039214632 ; 3039214640
    DOI 10.3390/books978-3-03921-464-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  7. Book: Lehninger principles of biochemistry

    Nelson, David L. / Cox, Michael M. / Lehninger, Albert L.

    2017  

    Title variant Principles of biochemistry
    Author's details David L. Nelson (Professor Emeritus of Biochemistry, University of Wisconsin-Madison), Michael M. Cox (Professor of Biochemistry University of Wisconsin-Madison)
    Keywords Biochemical Phenomena / physiology ; Biochemical Phenomena / genetics ; Energy Metabolism ; Biochemie
    Subject Biologische Chemie
    Language English
    Size xxxiv, 1172, AS1-AS34, G1-G20, I1-I45 Seiten, Illustrationen, Diagramme
    Edition Seventh edition, international edition
    Publisher W.H. Freeman, Macmillan Learning
    Publishing place New York
    Publishing country United States
    Document type Book
    HBZ-ID HT019256476
    ISBN 978-1-319-10824-3 ; 1-319-10824-5 ; 1-4641-2611-9 ; 978-1-4641-2611-6
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2018 A 522 available for loan (reading room) Lesesaal EG

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  8. Article ; Online: Transforming Nursing Education: Developing Augmented Reality Procedural Training.

    Lee, Deborah / Bathish, Melissa A / Nelson, Jeremy

    Cyberpsychology, behavior and social networking

    2024  

    Abstract: The shortage of nursing faculty and the scarcity of clinical placements have compelled researchers to investigate innovative solutions for procedural development to bridge the gap between didactic teaching and clinical experiences. This feasibility study ...

    Abstract The shortage of nursing faculty and the scarcity of clinical placements have compelled researchers to investigate innovative solutions for procedural development to bridge the gap between didactic teaching and clinical experiences. This feasibility study uses augmented reality (AR) with Microsoft HoloLens2 and Dynamics 365 Guides to train graduate nursing students on advanced nursing procedures, focusing on lumbar puncture. A convenience sample of 24 nurse practitioner students participated in the study. The System Usability Scale, Acceptability Scale, and Engagement Scale were used to assess participant's experiences and perceptions. The results are positive for the feasibility and acceptance of AR technology for procedural training. Participants found the HoloLens2 device easy to use and showed confidence in its functionality. The step-by-step instructions provided by Microsoft 365 Guides were understandable, useful, and satisfactory. The students reported high levels of engagement and found the AR experience to be helpful and motivating for learning. Faculty time was significantly reduced using the HoloLens2 for procedural training compared to traditional methods. This study demonstrates the potential for AR as an effective and efficient modality for nursing education. The findings support the integration of AR technology to enhance procedural development, address the challenges of limited clinical sites, and provide students with an immersive and self-paced learning experience. Additional studies will need to explore the impact of AR on clinical competency, patient outcomes, and cost-effectiveness. Overall, the use of AR technology may be useful and effective for nursing pedagogy.
    Language English
    Publishing date 2024-02-26
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2545735-4
    ISSN 2152-2723 ; 2152-2715
    ISSN (online) 2152-2723
    ISSN 2152-2715
    DOI 10.1089/cyber.2023.0403
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  9. Article ; Online: Computational Exploration of the Nature of Li

    Lee, Woojin / Nelson, Hosea M / Houk, K N

    The Journal of organic chemistry

    2023  Volume 88, Issue 6, Page(s) 3403–3408

    Abstract: The mechanisms of the C-H insertion reactions of vinyl carbocations formed by heterolysis of vinyl trifluoromethanesulfonates (triflates) by catalytic lithiated 1,3-bis[3,5-bis(trifluoromethyl)phenyl]urea ( ... ...

    Abstract The mechanisms of the C-H insertion reactions of vinyl carbocations formed by heterolysis of vinyl trifluoromethanesulfonates (triflates) by catalytic lithiated 1,3-bis[3,5-bis(trifluoromethyl)phenyl]urea (Li
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 123490-0
    ISSN 1520-6904 ; 0022-3263
    ISSN (online) 1520-6904
    ISSN 0022-3263
    DOI 10.1021/acs.joc.2c02178
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  10. Article ; Online: Ozone mitigations beyond the control of nitrogen oxides and volatile organic compounds.

    Lu, Keding / Zhou, Houhua / Lee, James / Nelson, Beth / Zhang, Yuanhang

    Science bulletin

    2023  Volume 68, Issue 18, Page(s) 1989–1992

    Language English
    Publishing date 2023-08-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2816140-3
    ISSN 2095-9281 ; 2095-9273
    ISSN (online) 2095-9281
    ISSN 2095-9273
    DOI 10.1016/j.scib.2023.07.051
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