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Article ; Online: Acute myeloid leukemia with neutrophilic differentiation in a 12-year-old African lion (Panthera leo).

Losada-Medina, Daniela / Henao-Duque, Ana M / Buitrago-Grisales, Diana I / Peña-Stadlin, Juliana

Journal of the American Veterinary Medical Association

2024 Volume 262, Issue 3, Page(s) 1–5

Abstract: ... of acute myeloid leukemia (AML) with neutrophilic differentiation in an African lion (Panthera leo).: Animal: A 12-year ...

Abstract	Objective: To describe the clinical presentation, progression, and diagnosis of acute myeloid leukemia (AML) with neutrophilic differentiation in an African lion (Panthera leo). Animal: A 12-year-old male African lion kept at a zoological institution in Colombia. Clinical presentation, progression, and procedures: The lion presented for anorexia, pale mucous membranes, and a hind limb lameness of acute onset. Feline leukemia virus testing was negative, and repeated blood samples revealed severe anemia, intermittent thrombocytopenia, lymphopenia, and neutrophilia. Coinfection with Anaplasma and Mycoplasma spp and chronic kidney disease were diagnosed based on clinicopathological findings. Treatment and outcome: The lion received symptomatic treatment, doxycycline, and methylprednisolone or prednisolone. Euthanasia was elected due to clinical deterioration and unresponsive anemia, despite the resolution of Anaplasma and Mycoplasma spp infections. AML with neutrophilic differentiation was diagnosed based on bone marrow cytology, histopathology, and immunohistochemistry. Clinical relevance: AML is a rare, aggressive hematopoietic disorder in domestic cats, although it has not yet been reported in nondomestic cats. This is the first description of the clinicopathological, histological, and immunohistochemical features of AML with neutrophilic differentiation in an FeLV-negative African lion that lacked circulating blasts.
MeSH term(s)	Male ; Cats ; Animals ; Lions ; Leukemia, Myeloid, Acute/diagnosis ; Leukemia, Myeloid, Acute/veterinary ; Bone Marrow ; Mycoplasma Infections/veterinary ; Anemia/veterinary ; Cat Diseases
Language	English
Publishing date	2024-01-03
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	390811-2
ISSN	1943-569X ; 0003-1488
ISSN (online)	1943-569X
ISSN	0003-1488
DOI	10.2460/javma.23.09.0530
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: LEO to GEO-SAR Interferences

Antonio Leanza / Marco Manzoni / Andrea Monti-Guarnieri / Marco di Clemente

Remote Sensing, Vol 11, Iss 14, p

Modelling and Performance Evaluation

2019 Volume 1720

Abstract: ... Earth orbiting (LEO) synthetic aperture radar (SAR) and received by GEO-stationary orbiting SAR ... The model properly accounts for the bistatic backscatter, the number of LEO-SAR satellites and their duty ... of many LEO-SAR. Examples and evaluations are made here for X band. ...

Abstract	This paper proposes a statistical model to evaluate the impact of the signal backscattered by low Earth orbiting (LEO) synthetic aperture radar (SAR) and received by GEO-stationary orbiting SAR. The model properly accounts for the bistatic backscatter, the number of LEO-SAR satellites and their duty cycles. The presence of many sun-synchronous, dawn-dusk satellites creates a 24 h periodic pattern in interference that should be considered in the acquisition plan of future geostationary SAR. The model, implemented by a numerical simulator, allows also the prediction of performance in future scenarios of many LEO-SAR. Examples and evaluations are made here for X band.
Keywords	geostationary SAR ; synthetic aperture radar ; radio frequency interference ; bistatic scattering ; Science ; Q
Language	English
Publishing date	2019-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Novel Signal Design and Performance Analysis in NavCom Based on LEO Constellation.

Ji, Jing / Liu, Yuting / Chen, Wei / Wu, Di / Lu, Hongyang / Zhang, Jiantong

Sensors (Basel, Switzerland)

2021 Volume 21, Issue 24

Abstract: The mega-launch of low Earth orbit satellites (LEOs) represents a critical opportunity to integrate ...

Abstract	The mega-launch of low Earth orbit satellites (LEOs) represents a critical opportunity to integrate navigation and communication (NavCom), but first, challenges related to signal design must be overcome. This article proposes a novel signal scheme named CE-OFDM-PM. Via research on the in-band or adjacent band, it was found that the proposed signal scheme was suitable for S-band and had a wide normalized power spectrum density (PSD), high peak-to-side lobe ratio (PSR), and multiple peaks in autocorrelation. In an analysis of the simulation performance evaluation in navigation and communication, it is found that the proposed signal scheme has the potential for high accuracy, a code tracking accuracy of up to 0.85 m, a small mutual influence between the proposed signal scheme and other schemes, excellent anti-interference properties, and a better performance at both short and long distances in terms of its anti-multipath capability. Furthermore, the proposed signal scheme shows the ability to communicate between satellites and the ground and is outstanding in terms of its bit error rate (BER), CNR, and energy per bit to noise power spectral density ratio (Eb/N0). From the technical, theoretical, and application perspectives, our proposed signal scheme has potential as an alternative scheme in future BDS, PNTs, and even 5G/B5G.
Language	English
Publishing date	2021-12-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s21248235
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Article ; Online: A Disruption Tolerant Distributed Routing Algorithm in LEO Satellite Networks

Jifeng Jin / Feng Tian / Zijian Yang / Hao Di / Guotong Li

Applied Sciences, Vol 12, Iss 3802, p

2022 Volume 3802

Abstract: The low earth orbit (LEO) constellation network has become a promising approach to provide global ...

Abstract	The low earth orbit (LEO) constellation network has become a promising approach to provide global communication services, due to its advantages in wide global coverage, low transmission delay, and convenient networking. However, the instability of the intersatellite laser terminal and the high relative speed between adjacent satellites cause frequent network topology changing problems for data routing. In this paper, a disruption tolerant distributed routing algorithm (DTDR) is proposed, where the satellites calculate the alternate path for transmission when the network topology changes, which improves the performance of packet loss. Specifically, each satellite maintains the intersatellite link (ISL) information within a specified number of hops. When an ISL state changes within the specified number of hops, the corresponding satellite calculates and switches to the detour path. Furthermore, the traffic is balanced through the detour process. Various simulations were constructed and show that the proposed algorithm outperforms the existing algorithm in terms of packet loss ratio and transmission delay.
Keywords	LEO satellite network ; distributed routing algorithm ; disruption tolerant ; packet drop rate ; load balance ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	629
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: LEO to GEO-SAR Interferences: Modelling and Performance Evaluation

Leanza, Antonio / Manzoni, Marco / Monti-Guarnieri, Andrea / di Clemente, Marco

Remote Sensing. 2019 July 20, v. 11, no. 14

2019

Abstract	This paper proposes a statistical model to evaluate the impact of the signal backscattered by low Earth orbiting (LEO) synthetic aperture radar (SAR) and received by GEO-stationary orbiting SAR. The model properly accounts for the bistatic backscatter, the number of LEO-SAR satellites and their duty cycles. The presence of many sun-synchronous, dawn-dusk satellites creates a 24 h periodic pattern in interference that should be considered in the acquisition plan of future geostationary SAR. The model, implemented by a numerical simulator, allows also the prediction of performance in future scenarios of many LEO-SAR. Examples and evaluations are made here for X band.
Keywords	prediction ; remote sensing ; satellites ; statistical models ; synthetic aperture radar
Language	English
Dates of publication	2019-0720
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2513863-7
ISSN	2072-4292
ISSN	2072-4292
DOI	10.3390/rs11141720
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Performance of two portable blood glucose meters for measuring blood glucose concentration in tigers (Panthera tigris) and lions (Panthera leo).

Capasso, Michele / Girolamo, Nicola Di / Silvestre, Pasqualino / Laricchiuta, Piero

Journal of the American Veterinary Medical Association

2019 Volume 254, Issue 3, Page(s) 399–408

Abstract: ... concentration in tigers (Panthera tigris) and lions (Panthera leo). DESIGN Method comparison and diagnostic ...

Abstract	OBJECTIVE To investigate the performance of a portable blood glucose meter (PBGM) designed for use in humans (hPBGM) and a PBGM designed for use in dogs and cats (vPBGM) when measuring blood glucose (BG) concentration in tigers (Panthera tigris) and lions (Panthera leo). DESIGN Method comparison and diagnostic accuracy study. SAMPLES 53 blood samples from tigers (n = 27) and lions (26). PROCEDURES BG concentration was measured with 2 identical hPBGMs, 2 identical vPBGMs, and a reference laboratory analyzer. Bland-Altman bias plots and Passing-Bablok regression analysis were used to assess agreement. Sensitivity, specificity, and positive and negative predictive values with corresponding 95% confidence intervals were calculated for use in assessing diagnostic accuracy of the investigated PBGMs. RESULTS Bias (95% limits of agreement) was -4.3 mg/dL (-46.3 to 37.6 mg/dL) for the hPBGM, -9.3 mg/dL (-64.6 to 46.0 mg/dL) for the vPBGM on canine setting, and 2.3 mg/dL (-47.9 to 52.6 mg/dL) for the vPBGM on feline setting. The hPBGM had better overall repeatability (coefficient of variation, 3.73%) than the vPBGM on canine (9.29%) or feline (9.44%) setting. Total error for the hPBGM, vPBGM on canine setting, and vPBGM on feline setting was 11.8%, 27.7%, and 20.9%, respectively. None of the PBGMs complied with the maximum allowable total error suggested by current guidelines when measuring BG in tigers and lions with hypo-, normo-, or hyperglycemia. CONCLUSIONS AND CLINICAL RELEVANCE Results indicated that the PBGMs evaluated were inadequate for measuring BG concentration in tigers and lions.
MeSH term(s)	Animals ; Blood Glucose ; Cat Diseases ; Cats ; Dog Diseases ; Dogs ; Humans ; Lions ; Tigers
Chemical Substances	Blood Glucose
Language	English
Publishing date	2019-01-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	390811-2
ISSN	1943-569X ; 0003-1488
ISSN (online)	1943-569X
ISSN	0003-1488
DOI	10.2460/javma.254.3.399
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 423: Show issues

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ab Jg. 2022: Lesesaal (EG)

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Article ; Online: A case of adrenal tumour in a lion (Panthera leo)

Maurizio Longo / Giuliano Ravasio / Donatella De Zani / Mauro Di Giancamillo / Vanessa Rabbogliatti / Davide Danilo Zani

International Journal of Health, Animal Science and Food Safety, Vol 2, Iss 1s (2015)

tomographic and ultrasonographic findings.

2015

Abstract: Adrenal gland tumors are common in humans and in several animal species. Studies concerning this neoplasia in human medicine indicate that clinical signs have a high variability. Adrenal adenomas can be occasionally observed in asymptomatic patients ... ...

Abstract	Adrenal gland tumors are common in humans and in several animal species. Studies concerning this neoplasia in human medicine indicate that clinical signs have a high variability. Adrenal adenomas can be occasionally observed in asymptomatic patients during tomographic studies while estrogen-secreting tumors, known as "feminizing adrenal tumors" (FATs), have been rarely reported. The aim of this study is to describe for the first time the Imaging findings of a captivity lion affected by a neoplastic secreting adrenal tumour. An 8 year-old male lion with progressive lack of secondary sex characteristics, disorexia and weight loss was referred to our Institution. The patient was chemically immobilized to undergo general clinical evaluation, hematologic, serum biochemical and hormonal profile, FIV and FeLV tests. Three months later a total body computed tomography and abdominal ultrasonography were performed. Liver and left adrenal lesions FNABs were performed. Imaging findings showed the presence of an extended expansive neoplastic lesion on the left adrenal gland (40x39x37 mm) with right adrenal gland atrophy. Generalized hepatopathy associated with a suspected intrahepatic cholestasis was confirmed by ultrasonography. Cytological evaluation ruled out the presence of neuroendocrine cells without malignancy evidences compatible with the adenomatous nature of the lesion, associated with moderate degenerative hepatopathy. Blood tests reported an estradiol concentration of 462 ng/dl. To our knowledge, this is the first description of adrenal mass in a lion associated with secondary feminization, inappetence and high values of hematic estradiol, referable to a feminizing adrenal tumor (FAT).
Keywords	adrenal tumor ; FATs ; lion ; Animal culture ; SF1-1100 ; Ecology ; QH540-549.5 ; Genetics ; QH426-470 ; Economic biology ; QH705-705.5
Subject code	630
Language	English
Publishing date	2015-07-01T00:00:00Z
Publisher	Università degli Studi di Milano
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Blood thiamine values in captive adult African lions (Panthera leo).

Hoover, John P / DiGesualdo, Cynthia L

Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians

2005 Volume 36, Issue 3, Page(s) 417–421

Abstract: Heparinized whole-blood samples from 22 adult African lions (Panthera leo) fed diets considered ...

Abstract	Heparinized whole-blood samples from 22 adult African lions (Panthera leo) fed diets considered nutritionally adequate in 10 American Zoo and Aquarium Association member zoos in North America were provided for this study. Blood thiamine values were estimated using a standard microbiological assay method. The mean +/- standard deviation for blood thiamine values was 249.3 +/- 43.5 nmol/L with a range in values from 160 to 350 nmol/L after exclusion of one outlier. There were no differences (P > 0.05) in the mean blood thiamine values of male and female lions, or of lions that were over and under 10 yr of age. This range (160 to 350 nmol/L) is proposed as a reasonable estimate of the expected range in blood thiamine values for captive adult African lions as currently fed in North American zoos.
MeSH term(s)	Age Factors ; Animal Nutritional Physiological Phenomena/physiology ; Animals ; Animals, Zoo/blood ; Female ; Lions/blood ; Male ; Nutritional Status ; Reference Values ; Sex Factors ; Thiamine/blood ; Vitamin B Complex/blood
Chemical Substances	Vitamin B Complex (12001-76-2) ; Thiamine (X66NSO3N35)
Language	English
Publishing date	2005-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2174930-9
ISSN	1937-2825 ; 1042-7260
ISSN (online)	1937-2825
ISSN	1042-7260
DOI	10.1638/04-071.1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Presumed primary thiamine deficiency in a young African lion (Panthera leo).

DiGesualdo, Cynthia L / Hoover, John P / Lorenz, Michael D

Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians

2005 Volume 36, Issue 3, Page(s) 512–514

Abstract: A 1-yr-old intact male African lion (Panthera leo) fed only beef muscle meat was evaluated ...

Abstract	A 1-yr-old intact male African lion (Panthera leo) fed only beef muscle meat was evaluated for episodes of hypermetric ataxia, generalized weakness and tonic-clonic front limb movements. A hemogram, biochemical profile, blood lead, electrocardiogram, survey radiographs, and brain computed tomography were normal. Cerebral spinal fluid analyses suggested mild inflammation. Acetylcholine receptor antibody and serologic tests for all infectious agents tested were negative. Clinical signs resolved completely 9 days after instituting oral thiamine (3 mg/kg/day) and a completely nutritional diet. This lion's pretreatment thiamine blood value (11 nmol/L) was markedly lower than that of a healthy lion (191 nmol/L) and a proposed reference range for adult African lions (160-350 nmol/L). The lion remained clinically normal 2 yr later when his blood thiamine value was 340 nmol/L. African lions can develop clinical primary thiamine deficiency and may respond favorably when thiamine treatment and adequate diet are instituted prior to irreversible neuronal necrosis.
MeSH term(s)	Animals ; Lions ; Male ; Thiamine/blood ; Thiamine/therapeutic use ; Thiamine Deficiency/blood ; Thiamine Deficiency/diagnosis ; Thiamine Deficiency/drug therapy ; Thiamine Deficiency/veterinary ; Treatment Outcome ; Vitamin B Complex/blood ; Vitamin B Complex/therapeutic use
Chemical Substances	Vitamin B Complex (12001-76-2) ; Thiamine (X66NSO3N35)
Language	English
Publishing date	2005-09
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2174930-9
ISSN	1937-2825 ; 1042-7260
ISSN (online)	1937-2825
ISSN	1042-7260
DOI	10.1638/04-070.1
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Book ; Online: Chapter Grain size, nutrients and heavy metals analysis to evaluate natural vs anthropogenic sources in the sea environment (Naples Bay, Eastern Tyrrhenian Sea)

MILIA, ALFONSA / francesco paolo, buonocunto / Di Leo, Antonella / Ferraro, Luciana / giandomenico, santina / Giordano, Laura / Violante, Crescenzo

(Monitoring of Mediterranean Coastal Areas: Problems and Measurement Techniques)

2022

Series title	Monitoring of Mediterranean Coastal Areas: Problems and Measurement Techniques
Keywords	The environment ; Heavy metals contamination ; Nutrients and grain size ; Submarine delta zone ; Naples Bay ; Tyrrhenian Sea
Language	English
Size	1 electronic resource (10 pages)
Publisher	Firenze University Press
Publishing place	Florence
Document type	Book ; Online
Note	English
HBZ-ID	HT030376199
ISBN	9791221500301
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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