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  1. Book: Pulmonary pathology

    Cagle, Philip T. / Kerr, Keith M.

    neoplastic and non-neoplastic

    (Encyclopedia of pathology ; Springer reference)

    2018  

    Author's details Philip T. Cagle, Keith M. Kerr editors
    Series title Encyclopedia of pathology
    Springer reference
    Keywords Adenocarcinoma ; Oncocytoma ; Rhabdomyosarcomas ; Coal Worker`s Pneumoconiosis ; Transplant-associated lymphoproliferative disorders
    Subject code 610
    Language English
    Size xxi, 453 Seiten, Illustrationen, 25.4 cm x 17.8 cm
    Publisher Springer International Publishing
    Publishing place Cham
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT019721635
    ISBN 978-3-319-69262-3 ; 3-319-69262-3 ; 9783319692630 ; 3319692631
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2018 A 918 available for loan (reading room) Lesesaal EG

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  2. Book: Soames' & Southam's oral pathology

    Robinson, Max / Hunter, Keith / Pemberton, Michael N. / Sloan, Philip

    2018  

    Title variant Oral pathology
    Author's details Max Robinson, Keith Hunter, Michael Pemberton, Philip Sloan
    Keywords Mouth/Diseases
    Language English
    Size xiv, 237 Seiten, Illustrationen, 28 cm
    Edition Fifth edition
    Publisher Oxford University Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    Note Previous edition: published as Oral pathology by J.V. Soames and J.C. Southam. 2005
    HBZ-ID HT019764600
    ISBN 978-0-19-969778-6 ; 0-19-969778-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2018 A 1205 available for loan (reading room) Lesesaal EG

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  3. Book: Chemistry, biochemistry and pharmacology of hydrogen sulfide

    Moore, Philip K. / Whiteman, Matt

    (Handbook of experimental pharmacology ; 230)

    2015  

    Author's details Philip K. Moore ; Matt Whiteman ed
    Series title Handbook of experimental pharmacology ; 230
    Collection
    Language English
    Size VI, 395 S., Ill., graph. Darst.
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    HBZ-ID HT018732859
    ISBN 978-3-319-18143-1 ; 9783319181448 ; 3-319-18143-2 ; 3319181440
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 2960 available for loan (reading room) Lesesaal EG

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  4. Article ; Online: Patient Outcomes After Peripheral Nerve Injury Depend on Bimanual Dexterity and Preserved Use of the Affected Hand.

    Kim, Taewon / Lohse, Keith R / Mackinnon, Susan E / Philip, Benjamin A

    Neurorehabilitation and neural repair

    2024  Volume 38, Issue 2, Page(s) 134–147

    Abstract: Background: Little is known about how peripheral nerve injury affects human performance, behavior, and life. Hand use choices are important for rehabilitation after unilateral impairment, but rarely measured, and are not changed by the normal course of ... ...

    Abstract Background: Little is known about how peripheral nerve injury affects human performance, behavior, and life. Hand use choices are important for rehabilitation after unilateral impairment, but rarely measured, and are not changed by the normal course of rehabilitation and daily life.
    Objective: To identify the relationship between hand use (L/R choices), motor performance, and patient-centered outcomes.
    Methods: Participants (n = 48) with unilateral peripheral nerve injury were assessed for hand use via Block Building Task, Motor Activity Log, and Edinburgh Handedness Inventory; dexterity (separately for each hand) via Nine-Hole Peg Test, Jebsen Taylor Hand Function Test, and a precision drawing task; patient-centered outcomes via surveys of disability, activity participation, and health-related quality of life; and injury-related factors including injury cause and affected nerve. Factor Analysis of Mixed Data was used to explore relationships between these variables. The data were analyzed under 2 approaches: comparing dominant hand (DH) versus non-dominant hand (NH), or affected versus unaffected hand.
    Results: The data were best explained by 5 dimensions. Good patient outcomes were associated with NH performance, DH performance (separately and secondarily to NH performance), and preserved function and use of the affected hand; whereas poor patient outcomes were associated with preserved but unused function of the affected hand.
    Conclusion: After unilateral peripheral nerve injury, hand function, hand usage, and patient life arise from a complex interaction of many factors. To optimize rehabilitation after unilateral impairment, new rehabilitation methods are needed to promote performance and use with the NH, as well as the injured hand.
    MeSH term(s) Humans ; Peripheral Nerve Injuries ; Quality of Life ; Hand ; Upper Extremity ; Functional Laterality/physiology
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1491637-x
    ISSN 1552-6844 ; 1545-9683 ; 0888-4390
    ISSN (online) 1552-6844
    ISSN 1545-9683 ; 0888-4390
    DOI 10.1177/15459683241227222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 3096: Show issues Location:
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  5. Book ; Online: Organic geochemistry of Cretaceous black shales from the Galicia Margin, supplementary data to: Meyers, Philip A; Dunham, Keith W; Ho, Eileen S (1987): Organic geochemistry of Cretaceous black shales from the Galicia Margin, Ocean Drilling Program Leg 103. Organic Geochemistry, 13(1-3), 89-96

    Meyers, Philip A / Dunham, Keith W / Ho, Eileen S

    1987  

    Abstract: Organic-carbon-rich "black shales" from three different Cretaceous episodes sampled during Ocean Drilling Program Leg 103 have been studied by organic geochemical methods. Rock-Eval analysis, carbon isotope data, and lipid biomarkers show organic matter ... ...

    Abstract Organic-carbon-rich "black shales" from three different Cretaceous episodes sampled during Ocean Drilling Program Leg 103 have been studied by organic geochemical methods. Rock-Eval analysis, carbon isotope data, and lipid biomarkers show organic matter to contain varying proportions of marine and continental materials. In Hauterivian-Barremian organic-carbon-rich turbiditic marlstones, major amounts of land-derived organic matter are found. Aptian-Albian black-colored shales are interspersed within green claystones, from which they differ by containing more marine organic matter. An abbreviated layer of black shale from the Cenomanian-Turonian boundary is dominated by well-preserved marine organic matter. Downslope transport and rapid reburial within a predominantly oxygenated deepwater setting created most of these examples of black shales, except for the Cenomanian-Turonian deposits in which deepwater anoxia may have been involved.
    Language English
    Dates of publication 1987-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/0146-6380(88)90029-0
    DOI 10.1594/PANGAEA.757260
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  6. Book ; Online: Organic geochemistry from different DSDP Holes in the subtropical South Atlantic Ocean, supplementary data to: Keswani, Sushiel R; Dunham, Keith W; Meyers, Philip A (1984): Organic geochemistry of late Cenozoic sediments from the subtropical South Atlantic Ocean. Marine Geology, 61(1), 25-42

    Keswani, Sushiel R / Dunham, Keith W / Meyers, Philip A

    1984  

    Abstract: Organic matter has been characterized in samples of Pleistocene, Pliocene, and Miocene sediments from seven Deep Sea Drilling Project sites in the subtropical South Atlantic Ocean. Organic carbon concentrations average 0.3% for most samples, and n- ... ...

    Abstract Organic matter has been characterized in samples of Pleistocene, Pliocene, and Miocene sediments from seven Deep Sea Drilling Project sites in the subtropical South Atlantic Ocean. Organic carbon concentrations average 0.3% for most samples, and n-alkanoic acid, n-alkanol, and alkane biomarkers indicate extensive microbial reworking of organic matter in these organic-carbon-lean sediments. Samples from the easternmost parts of the South Atlantic contain an average of 4.1% organic carbon and reflect the high productivity associated with the Benguela Current. Lipid biomarkers show less microbial reworking in these sediments. Eolian transport of land-derived hydrocarbons is evident at most of these oceanic locations.
    Language English
    Dates of publication 1984-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Online
    Note This dataset is supplement to doi:10.1016/0025-3227(84)90106-3
    DOI 10.1594/PANGAEA.761244
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  7. Book ; Conference proceedings ; Online: Organic geochemistry of Cretaceous black shales, supplementary data to: Dunham, Keith W; Meyers, Philip A; Ho, Eileen S (1988): Organic geochemistry of Cretaceous black shales and adjacent strata from the Galicia margin, North Atlantic Ocean. In: Boillot, G; Winterer, EL; et al. (eds.), Proceedings of the Ocean Drilling Program, Scientific Results, College Station, TX (Ocean Drilling Program), 103, 557-565

    Dunham, Keith W / Ho, Eileen S / Meyers, Philip A

    1988  

    Abstract: Organic-carbon-rich 'black shales' and adjacent organic-carbon-poor rocks from three different Cretaceous settings encountered during ODP Leg 103 have been studied by organic geochemical methods. Rock-Eval analysis, carbon isotope data, and lipid ... ...

    Abstract Organic-carbon-rich 'black shales' and adjacent organic-carbon-poor rocks from three different Cretaceous settings encountered during ODP Leg 103 have been studied by organic geochemical methods. Rock-Eval analysis, carbon isotope data, and lipid biomarkers show organic matter to contain varying proportions of marine and continental materials. In Hauterivian-Barremian organic-carbon-rich marlstone turbidites, large amounts of land-derived organic matter are found. Aptian-Albian black-colored shales are interspersed within green claystones, from which they differ by containing more marine organic matter. An abbreviated layer of black shale from the Cenomanian/Turonian boundary is dominated by well-preserved marine organic matter. Downslope transport and rapid reburial within a predominantly oxygenated deep-water setting created most of these examples of black shales, except for the Cenomanian-Turonian deposits in which deep-water anoxia may have been involved.
    Language English
    Dates of publication 1988-9999
    Size Online-Ressource
    Publisher PANGAEA - Data Publisher for Earth & Environmental Science
    Publishing place Bremen/Bremerhaven
    Document type Book ; Conference proceedings ; Online
    Note This dataset is supplement to doi:10.2973/odp.proc.sr.103.157.1988
    DOI 10.1594/PANGAEA.743874
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

    Full text online

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  8. Book: Transbronchial and endobronchial biopsies

    Cagle, Philip T. / Allen, Timothy C. / Kerr, Keith M.

    2009  

    Author's details Philip T. Cagle ; Timothy C. Allen ; Keith M. Kerr
    Keywords Lung Diseases / pathology ; Bronchial Diseases / pathology ; Bronchi / pathology ; Lung / pathology ; Biopsy / methods
    Language English
    Size XIII, 168 S. : zahlr. Ill.
    Publisher Wolters Kluwer, Lippincott Williams & Wilkins
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT015629973
    ISBN 978-0-7817-8517-4 ; 0-7817-8517-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 A 4537 order for loan Magazin
    Zugang zu Internetausgabe aus lizenzrechtlichen Gründen nicht verfügbar

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  9. Article ; Online: Influence of therapeutic plasma exchange treatment on short-term mortality of critically ill adult patients with sepsis-induced organ dysfunction: a systematic review and meta-analysis.

    Kuklin, Vladimir / Sovershaev, Michael / Bjerner, Johan / Keith, Philip / Scott, L Keith / Thomas, Owen Matthew Truscott / Szpirt, Wladimir / Rock, Gail / Stegmayr, Bernd

    Critical care (London, England)

    2024  Volume 28, Issue 1, Page(s) 12

    Abstract: Introduction: The impact of therapeutic plasma exchange (TPE) on short-term mortality in adult patients with sepsis-induced organ dysfunction remains uncertain. The objective of the study is to assess the effect of adjunct TPE in this setting through a ... ...

    Abstract Introduction: The impact of therapeutic plasma exchange (TPE) on short-term mortality in adult patients with sepsis-induced organ dysfunction remains uncertain. The objective of the study is to assess the effect of adjunct TPE in this setting through a comprehensive literature review.
    Methods: The National Library of Medicine's Medline, Ovid (Embase), the Cochrane Library database and clinicaltrial.gov from January 01, 1966, until October 01, 2022, were searched for terms: therapeutic plasma exchange, plasmapheresis, sepsis, and septic shock. We reviewed, selected and extracted data from relevant randomized clinical trials (RCTs) and matched cohort studies (MCSs) comparing short-term mortality in critically ill adult septic patients treated with standard therapy versus those receiving adjunct TPE. Risk of bias was assessed in the RCTs using Cochrane Collaboration tool and in MCSs using ROBINS-I tool. Summary statistics, risk ratios (RRs), and confidence intervals (CIs) were calculated using random effects model.
    Results: This systematic review included 937 adult critically ill septic patients from five RCTs (n = 367) and fifteen MCSs (n = 570). Of these total, 543 received treatment with TPE in addition to standard care. The meta-analysis includes all five RCTs and only six MCSs (n = 627). The adjunct TPE treatment (n = 300) showed a significant reduction in short-term mortality (RR 0.59, 95% CI 0.47-0.74, I2 3%) compared to standard therapy alone (n = 327). The systematic review of all 20 trials revealed that adding TPE to the standard therapy of critically ill septic patients resulted in faster clinical and/or laboratory recovery.
    Conclusions: Our comprehensive and up-to-date review demonstrates that adjunct TPE may provide potential survival benefits when compared to standard care for critically ill adult patients with sepsis-induced organ dysfunction. While results of this meta-analysis are encouraging, large well-designed randomized trials are required to identify the optimal patient population and TPE procedure characteristics prior to widespread adoption into practice.
    MeSH term(s) Adult ; Humans ; Plasma Exchange/methods ; Critical Illness/therapy ; Multiple Organ Failure/etiology ; Multiple Organ Failure/therapy ; Sepsis/therapy ; Sepsis/drug therapy ; Shock, Septic/drug therapy
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article ; Review
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04795-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5517: Show issues Location:
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  10. Article ; Online: Structural control of corneal transparency, refractive power and dynamics.

    Meek, Keith M / Knupp, Carlo / Lewis, Philip N / Morgan, Siân R / Hayes, Sally

    Eye (London, England)

    2024  

    Abstract: The cornea needs to be transparent to visible light and precisely curved to provide the correct refractive power. Both properties are governed by its structure. Corneal transparency arises from constructive interference of visible light due to the ... ...

    Abstract The cornea needs to be transparent to visible light and precisely curved to provide the correct refractive power. Both properties are governed by its structure. Corneal transparency arises from constructive interference of visible light due to the relatively ordered arrangement of collagen fibrils in the corneal stroma. The arrangement is controlled by the negatively charged proteoglycans surrounding the fibrils. Small changes in fibril organisation can be tolerated but larger changes cause light scattering. Corneal keratocytes do not scatter light because their refractive index matches that of the surrounding matrix. When activated, however, they become fibroblasts that have a lower refractive index. Modelling shows that this change in refractive index significantly increases light scatter. At the microscopic level, the corneal stroma has a lamellar structure, the parallel collagen fibrils within each lamella making a large angle with those of adjacent lamellae. X-ray scattering has shown that the lamellae have preferred orientations in the human cornea: inferior-superior and nasal-temporal in the central cornea and circumferential at the limbus. The directions at the centre of the cornea may help withstand the pull of the extraocular muscles whereas the pseudo-circular arrangement at the limbus supports the change in curvature between the cornea and sclera. Elastic fibres are also present; in the limbus they contain fibrillin microfibrils surrounding an elastin core, whereas at the centre of the cornea, they exist as thin bundles of fibrillin-rich microfibrils. We present a model based on the structure described above that may explain how the cornea withstands repeated pressure changes due to the ocular pulse.
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 91001-6
    ISSN 1476-5454 ; 0950-222X
    ISSN (online) 1476-5454
    ISSN 0950-222X
    DOI 10.1038/s41433-024-02969-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.B 3010: Show issues Location:
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    Zs.MO 603: Show issues

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